Compile Data Set for Download or QSAR

Found 97 hits with Last Name = 'd''amico' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4567 (4-anilinoquinazoline deriv. 2 | BMC163482 Compound...) Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 Show InChI InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR-TK in human A431 cell lysate assessed as reduction in EGF stimulated kinase activity after 60 mins using biotinylated peptide subs...				Eur J Med Chem 117: 283-91 (2016) Article DOI: 10.1016/j.ejmech.2016.04.002 BindingDB Entry DOI: 10.7270/Q2V126QC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468648 (CHEMBL4291851) Show SMILES CCOC(=O)c1c(Cc2ccc(Cl)c(Cl)c2)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H17Cl2NO3/c1-2-28-22(27)20-15-11-19(26)13-5-3-4-6-14(13)21(15)25-18(20)10-12-7-8-16(23)17(24)9-12/h3-9,11,25-26H,2,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468648 (CHEMBL4291851) Show SMILES CCOC(=O)c1c(Cc2ccc(Cl)c(Cl)c2)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H17Cl2NO3/c1-2-28-22(27)20-15-11-19(26)13-5-3-4-6-14(13)21(15)25-18(20)10-12-7-8-16(23)17(24)9-12/h3-9,11,25-26H,2,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM31133 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11l) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClNO3/c1-2-26-21(25)18-16-11-17(24)14-5-3-4-6-15(14)20(16)23-19(18)12-7-9-13(22)10-8-12/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468659 (CHEMBL4286295) Show SMILES CCOC(=O)c1c(Cc2c(F)cccc2F)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H17F2NO3/c1-2-28-22(27)20-15-11-19(26)12-6-3-4-7-13(12)21(15)25-18(20)10-14-16(23)8-5-9-17(14)24/h3-9,11,25-26H,2,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468641 (CHEMBL4285282) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1F Show InChI InChI=1S/C21H16FNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468667 (CHEMBL4282714) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cc(Br)ccc1F Show InChI InChI=1S/C21H15BrFNO3/c1-2-27-21(26)18-15-10-17(25)12-5-3-4-6-13(12)19(15)24-20(18)14-9-11(22)7-8-16(14)23/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468647 (CHEMBL4292906) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1C Show InChI InChI=1S/C22H19NO3/c1-3-26-22(25)19-17-12-18(24)15-10-6-7-11-16(15)20(17)23-21(19)14-9-5-4-8-13(14)2/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468646 (CHEMBL4289519) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C23H21NO3/c1-4-27-23(26)20-18-12-19(25)16-7-5-6-8-17(16)22(18)24-21(20)15-10-13(2)9-14(3)11-15/h5-12,24-25H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468652 (CHEMBL4281636) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cccc(C)c1 Show InChI InChI=1S/C22H19NO3/c1-3-26-22(25)19-17-12-18(24)15-9-4-5-10-16(15)21(17)23-20(19)14-8-6-7-13(2)11-14/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468671 (CHEMBL4282533) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H15ClO4/c1-2-25-21(24)18-16-11-17(23)14-5-3-4-6-15(14)20(16)26-19(18)12-7-9-13(22)10-8-12/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468655 (CHEMBL4286090) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H15Cl2NO3/c1-2-27-21(26)18-14-10-17(25)12-5-3-4-6-13(12)20(14)24-19(18)11-7-8-15(22)16(23)9-11/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468656 (CHEMBL4291203) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cccc(Br)c1 Show InChI InChI=1S/C21H16BrNO3/c1-2-26-21(25)18-16-11-17(24)14-8-3-4-9-15(14)20(16)23-19(18)12-6-5-7-13(22)10-12/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468658 (CHEMBL4278385) Show SMILES CCOC(=O)c1c(Cc2c(C)cc(C)cc2C)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C25H25NO3/c1-5-29-25(28)23-20-13-22(27)17-8-6-7-9-18(17)24(20)26-21(23)12-19-15(3)10-14(2)11-16(19)4/h6-11,13,26-27H,5,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468655 (CHEMBL4286090) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H15Cl2NO3/c1-2-27-21(26)18-14-10-17(25)12-5-3-4-6-13(12)20(14)24-19(18)11-7-8-15(22)16(23)9-11/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468672 (CHEMBL4281844) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1Cl Show InChI InChI=1S/C21H16ClNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468652 (CHEMBL4281636) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cccc(C)c1 Show InChI InChI=1S/C22H19NO3/c1-3-26-22(25)19-17-12-18(24)15-9-4-5-10-16(15)21(17)23-20(19)14-8-6-7-13(2)11-14/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468641 (CHEMBL4285282) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1F Show InChI InChI=1S/C21H16FNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468643 (CHEMBL4289715) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1Br Show InChI InChI=1S/C21H16BrNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468640 (CHEMBL4281231) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1Br Show InChI InChI=1S/C21H15BrO4/c1-2-25-21(24)18-15-11-17(23)12-7-3-4-8-13(12)19(15)26-20(18)14-9-5-6-10-16(14)22/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468659 (CHEMBL4286295) Show SMILES CCOC(=O)c1c(Cc2c(F)cccc2F)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H17F2NO3/c1-2-28-22(27)20-15-11-19(26)12-6-3-4-7-13(12)21(15)25-18(20)10-14-16(23)8-5-9-17(14)24/h3-9,11,25-26H,2,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468653 (CHEMBL4285059) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1OC Show InChI InChI=1S/C22H19NO4/c1-3-27-22(25)19-16-12-17(24)13-8-4-5-9-14(13)20(16)23-21(19)15-10-6-7-11-18(15)26-2/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468643 (CHEMBL4289715) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1Br Show InChI InChI=1S/C21H16BrNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468653 (CHEMBL4285059) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1OC Show InChI InChI=1S/C22H19NO4/c1-3-27-22(25)19-16-12-17(24)13-8-4-5-9-14(13)20(16)23-21(19)15-10-6-7-11-18(15)26-2/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468656 (CHEMBL4291203) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cccc(Br)c1 Show InChI InChI=1S/C21H16BrNO3/c1-2-26-21(25)18-16-11-17(24)14-8-3-4-9-15(14)20(16)23-19(18)12-6-5-7-13(22)10-12/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468662 (CHEMBL4289327) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1OC Show InChI InChI=1S/C22H18O5/c1-3-26-22(24)19-16-12-17(23)13-8-4-5-9-14(13)20(16)27-21(19)15-10-6-7-11-18(15)25-2/h4-12,23H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468667 (CHEMBL4282714) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cc(Br)ccc1F Show InChI InChI=1S/C21H15BrFNO3/c1-2-27-21(26)18-15-10-17(25)12-5-3-4-6-13(12)19(15)24-20(18)14-9-11(22)7-8-16(14)23/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468672 (CHEMBL4281844) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1Cl Show InChI InChI=1S/C21H16ClNO3/c1-2-26-21(25)18-15-11-17(24)12-7-3-4-8-13(12)19(15)23-20(18)14-9-5-6-10-16(14)22/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468654 (CHEMBL4293319) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Br)cc1F Show InChI InChI=1S/C21H15BrFNO3/c1-2-27-21(26)18-15-10-17(25)12-5-3-4-6-13(12)19(15)24-20(18)14-8-7-11(22)9-16(14)23/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468658 (CHEMBL4278385) Show SMILES CCOC(=O)c1c(Cc2c(C)cc(C)cc2C)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C25H25NO3/c1-5-29-25(28)23-20-13-22(27)17-8-6-7-9-18(17)24(20)26-21(23)12-19-15(3)10-14(2)11-16(19)4/h6-11,13,26-27H,5,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468646 (CHEMBL4289519) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C23H21NO3/c1-4-27-23(26)20-18-12-19(25)16-7-5-6-8-17(16)22(18)24-21(20)15-10-13(2)9-14(3)11-15/h5-12,24-25H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM31123 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11b) Show SMILES CCOC(=O)c1c(Cc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H18ClNO3/c1-2-27-22(26)20-16-12-19(25)14-8-4-5-9-15(14)21(16)24-18(20)11-13-7-3-6-10-17(13)23/h3-10,12,24-25H,2,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	301	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM31123 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11b) Show SMILES CCOC(=O)c1c(Cc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H18ClNO3/c1-2-27-22(26)20-16-12-19(25)14-8-4-5-9-15(14)21(16)24-18(20)11-13-7-3-6-10-17(13)23/h3-10,12,24-25H,2,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM31133 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11l) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClNO3/c1-2-26-21(25)18-16-11-17(24)14-5-3-4-6-15(14)20(16)23-19(18)12-7-9-13(22)10-8-12/h3-11,23-24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468651 (CHEMBL4286990) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1Cl Show InChI InChI=1S/C21H15ClO4/c1-2-25-21(24)18-15-11-17(23)12-7-3-4-8-13(12)19(15)26-20(18)14-9-5-6-10-16(14)22/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468673 (CHEMBL4291848) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1F Show InChI InChI=1S/C21H15FO4/c1-2-25-21(24)18-15-11-17(23)12-7-3-4-8-13(12)19(15)26-20(18)14-9-5-6-10-16(14)22/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468657 (CHEMBL601110 | GNF-Pf-3537) Show SMILES CCOC(=O)c1c(C)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C16H15NO3/c1-3-20-16(19)14-9(2)17-15-11-7-5-4-6-10(11)13(18)8-12(14)15/h4-8,17-18H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468647 (CHEMBL4292906) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccccc1C Show InChI InChI=1S/C22H19NO3/c1-3-26-22(25)19-17-12-18(24)15-10-6-7-11-16(15)20(17)23-21(19)14-9-5-4-8-13(14)2/h4-12,23-24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468650 (CHEMBL4290404) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1cccc(Cl)c1 Show InChI InChI=1S/C21H15ClO4/c1-2-25-21(24)18-16-11-17(23)14-8-3-4-9-15(14)20(16)26-19(18)12-6-5-7-13(22)10-12/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468657 (CHEMBL601110 | GNF-Pf-3537) Show SMILES CCOC(=O)c1c(C)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C16H15NO3/c1-3-20-16(19)14-9(2)17-15-11-7-5-4-6-10(11)13(18)8-12(14)15/h4-8,17-18H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50468655 (CHEMBL4286090) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H15Cl2NO3/c1-2-27-21(26)18-14-10-17(25)12-5-3-4-6-13(12)20(14)24-19(18)11-7-8-15(22)16(23)9-11/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of mPGES-1 in microsomal membranes isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by PGH2 addition m...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468673 (CHEMBL4291848) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1F Show InChI InChI=1S/C21H15FO4/c1-2-25-21(24)18-15-11-17(23)12-7-3-4-8-13(12)19(15)26-20(18)14-9-5-6-10-16(14)22/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468642 (CHEMBL4292720) Show SMILES CCOC(=O)c1c(oc2ccc(O)cc12)-c1ccccc1Cl Show InChI InChI=1S/C17H13ClO4/c1-2-21-17(20)15-12-9-10(19)7-8-14(12)22-16(15)11-5-3-4-6-13(11)18/h3-9,19H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468660 (CHEMBL4283989) Show SMILES CCOC(=O)c1c(Cc2c(Cl)cccc2Cl)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H17Cl2NO3/c1-2-28-22(27)20-15-11-19(26)12-6-3-4-7-13(12)21(15)25-18(20)10-14-16(23)8-5-9-17(14)24/h3-9,11,25-26H,2,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	782	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468640 (CHEMBL4281231) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccccc1Br Show InChI InChI=1S/C21H15BrO4/c1-2-25-21(24)18-15-11-17(23)12-7-3-4-8-13(12)19(15)26-20(18)14-9-5-6-10-16(14)22/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468644 (CHEMBL4279062) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1cccc(Br)c1 Show InChI InChI=1S/C21H15BrO4/c1-2-25-21(24)18-16-11-17(23)14-8-3-4-9-15(14)20(16)26-19(18)12-6-5-7-13(22)10-12/h3-11,23H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468654 (CHEMBL4293319) Show SMILES CCOC(=O)c1c([nH]c2c1cc(O)c1ccccc21)-c1ccc(Br)cc1F Show InChI InChI=1S/C21H15BrFNO3/c1-2-27-21(26)18-15-10-17(25)12-5-3-4-6-13(12)19(15)24-20(18)14-8-7-11(22)9-16(14)23/h3-10,24-25H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50174346 (CHEMBL3809045) Show SMILES Brc1cccc(Nc2ncnc3ccc(cc23)N=C=S)c1 Show InChI InChI=1S/C15H9BrN4S/c16-10-2-1-3-12(6-10)20-15-13-7-11(19-9-21)4-5-14(13)17-8-18-15/h1-8H,(H,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR-TK in human A431 cell lysate assessed as reduction in EGF stimulated kinase activity after 60 mins using biotinylated peptide subs...				Eur J Med Chem 117: 283-91 (2016) Article DOI: 10.1016/j.ejmech.2016.04.002 BindingDB Entry DOI: 10.7270/Q2V126QC
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM31123 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11b) Show SMILES CCOC(=O)c1c(Cc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C22H18ClNO3/c1-2-27-22(26)20-16-12-19(25)14-8-4-5-9-15(14)21(16)24-18(20)11-13-7-3-6-10-17(13)23/h3-10,12,24-25H,2,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of mPGES-1 in microsomal membranes isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by PGH2 addition m...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50468661 (CHEMBL4285919) Show SMILES CCOC(=O)c1c(oc2c1cc(O)c1ccccc21)-c1ccc(Br)cc1F Show InChI InChI=1S/C21H14BrFO4/c1-2-26-21(25)18-15-10-17(24)12-5-3-4-6-13(12)19(15)27-20(18)14-8-7-11(22)9-16(14)23/h3-10,24H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi della Campania Luigi Vanvitelli Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...				Eur J Med Chem 155: 946-960 (2018) Article DOI: 10.1016/j.ejmech.2018.05.041 BindingDB Entry DOI: 10.7270/Q2WM1H3T
					More data for this Ligand-Target Pair

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