Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'd''andrea' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50355501 (INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...) Show SMILES N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 |r| Show InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50355501 (INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...) Show SMILES N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 |r| Show InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332294 (CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...) Show SMILES Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50355501 (INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...) Show SMILES N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 |r| Show InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332296 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)S(N)(=O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N6O3S/c16-10-5-2-6-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-3-1-4-9(7-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332302 ((5-amino-3-(3-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-6-3-5-10(9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)7-4-8-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332300 (4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2ccc(cc2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-2-1-3-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-6-4-8(5-7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332300 (4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2ccc(cc2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-2-1-3-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-6-4-8(5-7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332302 ((5-amino-3-(3-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-6-3-5-10(9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)7-4-8-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332296 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)S(N)(=O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N6O3S/c16-10-5-2-6-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-3-1-4-9(7-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332303 ((5-amino-3-(4-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-8-6-10(7-9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)4-3-5-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332303 ((5-amino-3-(4-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-8-6-10(7-9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)4-3-5-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332294 (CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...) Show SMILES Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332294 (CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...) Show SMILES Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332304 ((5-amino-3-(pyridin-3-ylamino)-1H-1,2,4-triazol-1-...) Show SMILES Nc1nc(Nc2cccnc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C14H10F2N6O/c15-9-4-1-5-10(16)11(9)12(23)22-13(17)20-14(21-22)19-8-3-2-6-18-7-8/h1-7H,(H3,17,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332301 ((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...) Show SMILES Nc1nc(Nc2ccccc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H11F2N5O/c16-10-7-4-8-11(17)12(10)13(23)22-14(18)20-15(21-22)19-9-5-2-1-3-6-9/h1-8H,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332304 ((5-amino-3-(pyridin-3-ylamino)-1H-1,2,4-triazol-1-...) Show SMILES Nc1nc(Nc2cccnc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C14H10F2N6O/c15-9-4-1-5-10(16)11(9)12(23)22-13(17)20-14(21-22)19-8-3-2-6-18-7-8/h1-7H,(H3,17,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332301 ((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...) Show SMILES Nc1nc(Nc2ccccc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H11F2N5O/c16-10-7-4-8-11(17)12(10)13(23)22-14(18)20-15(21-22)19-9-5-2-1-3-6-9/h1-8H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50355501 (INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...) Show SMILES N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 |r| Show InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332299 (CHEMBL1287940 | methyl 4-(5-amino-1-(2,6-difluorob...) Show SMILES COC(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H13F2N5O3/c1-27-15(26)9-5-7-10(8-6-9)21-17-22-16(20)24(23-17)14(25)13-11(18)3-2-4-12(13)19/h2-8H,1H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332298 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-5-2-6-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-4-1-3-8(7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332298 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-5-2-6-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-4-1-3-8(7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332299 (CHEMBL1287940 | methyl 4-(5-amino-1-(2,6-difluorob...) Show SMILES COC(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H13F2N5O3/c1-27-15(26)9-5-7-10(8-6-9)21-17-22-16(20)24(23-17)14(25)13-11(18)3-2-4-12(13)19/h2-8H,1H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332303 ((5-amino-3-(4-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-8-6-10(7-9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)4-3-5-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50332297 (CHEMBL1287812 | ethyl 3-(5-amino-1-(2,6-difluorobe...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C18H15F2N5O3/c1-2-28-16(27)10-5-3-6-11(9-10)22-18-23-17(21)25(24-18)15(26)14-12(19)7-4-8-13(14)20/h3-9H,2H2,1H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK1 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332294 (CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...) Show SMILES Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332296 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)S(N)(=O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N6O3S/c16-10-5-2-6-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-3-1-4-9(7-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332300 (4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2ccc(cc2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-2-1-3-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-6-4-8(5-7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332297 (CHEMBL1287812 | ethyl 3-(5-amino-1-(2,6-difluorobe...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C18H15F2N5O3/c1-2-28-16(27)10-5-3-6-11(9-10)22-18-23-17(21)25(24-18)15(26)14-12(19)7-4-8-13(14)20/h3-9H,2H2,1H3,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332302 ((5-amino-3-(3-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-6-3-5-10(9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)7-4-8-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332300 (4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2ccc(cc2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-2-1-3-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-6-4-8(5-7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332296 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)S(N)(=O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H12F2N6O3S/c16-10-5-2-6-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-3-1-4-9(7-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332303 ((5-amino-3-(4-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-8-6-10(7-9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)4-3-5-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332301 ((5-amino-3-(phenylamino)-1H-1,2,4-triazol-1-yl)(2,...) Show SMILES Nc1nc(Nc2ccccc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C15H11F2N5O/c16-10-7-4-8-11(17)12(10)13(23)22-14(18)20-15(21-22)19-9-5-2-1-3-6-9/h1-8H,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332302 ((5-amino-3-(3-(dimethylamino)phenylamino)-1H-1,2,4...) Show SMILES CN(C)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C17H16F2N6O/c1-24(2)11-6-3-5-10(9-11)21-17-22-16(20)25(23-17)15(26)14-12(18)7-4-8-13(14)19/h3-9H,1-2H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332304 ((5-amino-3-(pyridin-3-ylamino)-1H-1,2,4-triazol-1-...) Show SMILES Nc1nc(Nc2cccnc2)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C14H10F2N6O/c15-9-4-1-5-10(16)11(9)12(23)22-13(17)20-14(21-22)19-8-3-2-6-18-7-8/h1-7H,(H3,17,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332305 (CHEMBL1288062 | ethyl 3-(5-amino-1-(2-fluorobenzoy...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccccc2F)c1 Show InChI InChI=1S/C18H16FN5O3/c1-2-27-16(26)11-6-5-7-12(10-11)21-18-22-17(20)24(23-18)15(25)13-8-3-4-9-14(13)19/h3-10H,2H2,1H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332298 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-5-2-6-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-4-1-3-8(7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332299 (CHEMBL1287940 | methyl 4-(5-amino-1-(2,6-difluorob...) Show SMILES COC(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H13F2N5O3/c1-27-15(26)9-5-7-10(8-6-9)21-17-22-16(20)24(23-17)14(25)13-11(18)3-2-4-12(13)19/h2-8H,1H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332305 (CHEMBL1288062 | ethyl 3-(5-amino-1-(2-fluorobenzoy...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccccc2F)c1 Show InChI InChI=1S/C18H16FN5O3/c1-2-27-16(26)11-6-5-7-12(10-11)21-18-22-17(20)24(23-18)15(25)13-8-3-4-9-14(13)19/h3-10H,2H2,1H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332306 (CHEMBL1287970 | ethyl 3-(3-amino-1-(2,6-difluorobe...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)nn2C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C18H15F2N5O3/c1-2-28-16(27)10-5-3-6-11(9-10)22-18-23-17(21)24-25(18)15(26)14-12(19)7-4-8-13(14)20/h3-9H,2H2,1H3,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332307 (CHEMBL1288769 | ethyl 3-(5-amino-1H-1,2,4-triazol-...) Show SMILES CCOC(=O)c1cccc(Nc2nnc(N)[nH]2)c1 Show InChI InChI=1S/C11H13N5O2/c1-2-18-9(17)7-4-3-5-8(6-7)13-11-14-10(12)15-16-11/h3-6H,2H2,1H3,(H4,12,13,14,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332299 (CHEMBL1287940 | methyl 4-(5-amino-1-(2,6-difluorob...) Show SMILES COC(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C17H13F2N5O3/c1-27-15(26)9-5-7-10(8-6-9)21-17-22-16(20)24(23-17)14(25)13-11(18)3-2-4-12(13)19/h2-8H,1H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332298 (3-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazo...) Show SMILES Nc1nc(Nc2cccc(c2)C(O)=O)nn1C(=O)c1c(F)cccc1F Show InChI InChI=1S/C16H11F2N5O3/c17-10-5-2-6-11(18)12(10)13(24)23-15(19)21-16(22-23)20-9-4-1-3-8(7-9)14(25)26/h1-7H,(H,25,26)(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50332297 (CHEMBL1287812 | ethyl 3-(5-amino-1-(2,6-difluorobe...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C18H15F2N5O3/c1-2-28-16(27)10-5-3-6-11(9-10)22-18-23-17(21)25(24-18)15(26)14-12(19)7-4-8-13(14)20/h3-9H,2H2,1H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332308 (CHEMBL1288033 | ethyl 3-(5-amino-1-benzoyl-1H-1,2,...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C18H17N5O3/c1-2-26-16(25)13-9-6-10-14(11-13)20-18-21-17(19)23(22-18)15(24)12-7-4-3-5-8-12/h3-11H,2H2,1H3,(H3,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332309 (CHEMBL1288063 | ethyl 3-(5-amino-1-(4-(trifluorome...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C19H16F3N5O3/c1-2-30-16(29)12-4-3-5-14(10-12)24-18-25-17(23)27(26-18)15(28)11-6-8-13(9-7-11)19(20,21)22/h3-10H,2H2,1H3,(H3,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332310 (CHEMBL1288093 | ethyl 3-(5-amino-1-(4-(dimethylami...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccc(cc2)N(C)C)c1 Show InChI InChI=1S/C20H22N6O3/c1-4-29-18(28)14-6-5-7-15(12-14)22-20-23-19(21)26(24-20)17(27)13-8-10-16(11-9-13)25(2)3/h5-12H,4H2,1-3H3,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50332297 (CHEMBL1287812 | ethyl 3-(5-amino-1-(2,6-difluorobe...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C18H15F2N5O3/c1-2-28-16(27)10-5-3-6-11(9-10)22-18-23-17(21)25(24-18)15(26)14-12(19)7-4-8-13(14)20/h3-9H,2H2,1H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant JAK3 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50332311 (CHEMBL1288094 | ethyl 3-(5-amino-1-(furan-2-carbon...) Show SMILES CCOC(=O)c1cccc(Nc2nc(N)n(n2)C(=O)c2ccco2)c1 Show InChI InChI=1S/C16H15N5O4/c1-2-24-14(23)10-5-3-6-11(9-10)18-16-19-15(17)21(20-16)13(22)12-7-4-8-25-12/h3-9H,2H2,1H3,(H3,17,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Inhibition of human recombinant TYK2 by TR-FRET assay				Bioorg Med Chem Lett 20: 7454-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.026 BindingDB Entry DOI: 10.7270/Q22B901J
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 60 total )  |  Next  |  Last  >>

Jump to: