Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'deleuze-masquefa' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061323 (1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-piperidin-3...) Show SMILES OC1CCCN(C1)C1(CCCCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C19H25NOS/c21-16-8-6-12-20(14-16)19(10-4-1-5-11-19)18-13-15-7-2-3-9-17(15)22-18/h2-3,7,9,13,16,21H,1,4-6,8,10-12,14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity of compound against [3H]-BTCP binding to neuronal dopamine transporter of rat striatal membrane				J Med Chem 40: 4019-25 (1998) Article DOI: 10.1021/jm970078z BindingDB Entry DOI: 10.7270/Q26972P1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005534 (1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity of compound against [3H]-BTCP binding to neuronal dopamine transporter of rat striatal membrane				J Med Chem 40: 4019-25 (1998) Article DOI: 10.1021/jm970078z BindingDB Entry DOI: 10.7270/Q26972P1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061320 (1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-piperidin-4...) Show SMILES OC1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C19H25NOS/c21-16-8-12-20(13-9-16)19(10-4-1-5-11-19)18-14-15-6-2-3-7-17(15)22-18/h2-3,6-7,14,16,21H,1,4-5,8-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.9	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity of compound against [3H]-BTCP binding to neuronal dopamine transporter of rat striatal membrane				J Med Chem 40: 4019-25 (1998) Article DOI: 10.1021/jm970078z BindingDB Entry DOI: 10.7270/Q26972P1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061321 (4-Benzo[b]thiophen-2-yl-4-piperidin-1-yl-cyclohexa...) Show SMILES O[C@H]1CC[C@](CC1)(N1CCCCC1)c1cc2ccccc2s1 |wU:4.7,1.0,(9.01,-15.85,;9.01,-14.31,;7.68,-13.54,;7.68,-12,;9.01,-11.23,;10.34,-12,;10.34,-13.54,;10.34,-10.45,;11.67,-11.21,;13,-10.44,;12.98,-8.9,;11.65,-8.14,;10.32,-8.91,;8.24,-9.89,;8.84,-8.45,;7.68,-7.44,;7.66,-5.9,;6.33,-5.13,;4.99,-5.93,;5,-7.47,;6.35,-8.22,;6.68,-9.74,)| Show InChI InChI=1S/C19H25NOS/c21-16-8-10-19(11-9-16,20-12-4-1-5-13-20)18-14-15-6-2-3-7-17(15)22-18/h2-3,6-7,14,16,21H,1,4-5,8-13H2/t16-,19+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53.4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity of compound against [3H]-BTCP binding to neuronal dopamine transporter of rat striatal membrane				J Med Chem 40: 4019-25 (1998) Article DOI: 10.1021/jm970078z BindingDB Entry DOI: 10.7270/Q26972P1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50061322 (4-Benzo[b]thiophen-2-yl-4-piperidin-1-yl-cyclohexa...) Show SMILES O[C@H]1CC[C@@](CC1)(N1CCCCC1)c1cc2ccccc2s1 |wU:4.7,wD:1.0,(9.01,-15.85,;9.01,-14.31,;10.34,-13.54,;10.34,-12,;9.01,-11.23,;7.68,-12,;7.68,-13.54,;10.34,-10.45,;11.67,-11.21,;13,-10.44,;12.98,-8.9,;11.65,-8.14,;10.32,-8.91,;8.24,-9.89,;8.84,-8.45,;7.68,-7.44,;7.66,-5.9,;6.33,-5.13,;4.99,-5.93,;5,-7.47,;6.35,-8.22,;6.68,-9.74,)| Show InChI InChI=1S/C19H25NOS/c21-16-8-10-19(11-9-16,20-12-4-1-5-13-20)18-14-15-6-2-3-7-17(15)22-18/h2-3,6-7,14,16,21H,1,4-5,8-13H2/t16-,19-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity of compound against [3H]-BTCP binding to neuronal dopamine transporter of rat striatal membrane				J Med Chem 40: 4019-25 (1998) Article DOI: 10.1021/jm970078z BindingDB Entry DOI: 10.7270/Q26972P1
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515285 (CHEMBL4560840) Show SMILES CCCCc1cc2c(N)nc3ccccc3n2n1 Show InChI InChI=1S/C14H16N4/c1-2-3-6-10-9-13-14(15)16-11-7-4-5-8-12(11)18(13)17-10/h4-5,7-9H,2-3,6H2,1H3,(H2,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515291 (CHEMBL4580838) Show SMILES CC(C)Cc1cc2c(N)nc3ccccc3n2n1 Show InChI InChI=1S/C14H16N4/c1-9(2)7-10-8-13-14(15)16-11-5-3-4-6-12(11)18(13)17-10/h3-6,8-9H,7H2,1-2H3,(H2,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515296 (CHEMBL4471676) Show SMILES CCCCc1cc2c(N)nc3ccc(C)cc3n2n1 Show InChI InChI=1S/C15H18N4/c1-3-4-5-11-9-14-15(16)17-12-7-6-10(2)8-13(12)19(14)18-11/h6-9H,3-5H2,1-2H3,(H2,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515297 (CHEMBL4438604) Show SMILES CCCCc1ncc2c(N)nc3ccccc3n12 Show InChI InChI=1S/C14H16N4/c1-2-3-8-13-16-9-12-14(15)17-10-6-4-5-7-11(10)18(12)13/h4-7,9H,2-3,8H2,1H3,(H2,15,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515288 (CHEMBL4476592) Show SMILES CC(C)CCc1ncc2c(N)nc3ccccc3n12 Show InChI InChI=1S/C15H18N4/c1-10(2)7-8-14-17-9-13-15(16)18-11-5-3-4-6-12(11)19(13)14/h3-6,9-10H,7-8H2,1-2H3,(H2,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515287 (CHEMBL4576117) Show SMILES CCCCCc1ncc2c(N)nc3ccccc3n12 Show InChI InChI=1S/C15H18N4/c1-2-3-4-9-14-17-10-13-15(16)18-11-7-5-6-8-12(11)19(13)14/h5-8,10H,2-4,9H2,1H3,(H2,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515280 (CHEMBL4473255) Show SMILES COCC#Cc1cnc2c(N)nccn12 Show InChI InChI=1S/C10H10N4O/c1-15-6-2-3-8-7-13-10-9(11)12-4-5-14(8)10/h4-5,7H,6H2,1H3,(H2,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515293 (CHEMBL4563826) Show SMILES CCCC#Cc1cnc2c(N)nccn12 Show InChI InChI=1S/C11H12N4/c1-2-3-4-5-9-8-14-11-10(12)13-6-7-15(9)11/h6-8H,2-3H2,1H3,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515283 (CHEMBL4439607) Show SMILES CC(C)CCc1cnc2c(N)nccn12 Show InChI InChI=1S/C11H16N4/c1-8(2)3-4-9-7-14-11-10(12)13-5-6-15(9)11/h5-8H,3-4H2,1-2H3,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515286 (CHEMBL4473248) Show SMILES CCCCc1cc2c(N)nc3cccc(C)c3n2n1 Show InChI InChI=1S/C15H18N4/c1-3-4-7-11-9-13-15(16)17-12-8-5-6-10(2)14(12)19(13)18-11/h5-6,8-9H,3-4,7H2,1-2H3,(H2,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515284 (CHEMBL4568083) Show SMILES COCCCc1cnc2c(N)nccn12 Show InChI InChI=1S/C10H14N4O/c1-15-6-2-3-8-7-13-10-9(11)12-4-5-14(8)10/h4-5,7H,2-3,6H2,1H3,(H2,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515278 (CHEMBL4547833) Show SMILES CC(C)C#Cc1cnc2c(N)nccn12 Show InChI InChI=1S/C11H12N4/c1-8(2)3-4-9-7-14-11-10(12)13-5-6-15(9)11/h5-8H,1-2H3,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515290 (CHEMBL4550776) Show SMILES CCCCCc1cnc2c(N)nccn12 Show InChI InChI=1S/C11H16N4/c1-2-3-4-5-9-8-14-11-10(12)13-6-7-15(9)11/h6-8H,2-5H2,1H3,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515281 (CHEMBL4548717) Show SMILES CCCCC#Cc1cnc2c(N)nccn12 Show InChI InChI=1S/C12H14N4/c1-2-3-4-5-6-10-9-15-12-11(13)14-7-8-16(10)12/h7-9H,2-4H2,1H3,(H2,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515282 (CHEMBL4470846) Show SMILES Nc1nccn2c(cnc12)C#CCCCO Show InChI InChI=1S/C11H12N4O/c12-10-11-14-8-9(4-2-1-3-7-16)15(11)6-5-13-10/h5-6,8,16H,1,3,7H2,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515289 (CHEMBL4467863) Show SMILES CCCCCCc1ncc2c(N)nc3ccccc3n12 Show InChI InChI=1S/C16H20N4/c1-2-3-4-5-10-15-18-11-14-16(17)19-12-8-6-7-9-13(12)20(14)15/h6-9,11H,2-5,10H2,1H3,(H2,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515292 (CHEMBL4588791) Show SMILES Nc1nccn2c(CCCCCO)cnc12 Show InChI InChI=1S/C11H16N4O/c12-10-11-14-8-9(4-2-1-3-7-16)15(11)6-5-13-10/h5-6,8,16H,1-4,7H2,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515294 (CHEMBL4462769) Show SMILES Nc1nccn2c(cnc12)C#CCCO Show InChI InChI=1S/C10H10N4O/c11-9-10-13-7-8(3-1-2-6-15)14(10)5-4-12-9/h4-5,7,15H,2,6H2,(H2,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515279 (CHEMBL4467162) Show SMILES Nc1nccn2c(CCCCO)cnc12 Show InChI InChI=1S/C10H14N4O/c11-9-10-13-7-8(3-1-2-6-15)14(10)5-4-12-9/h4-5,7,15H,1-3,6H2,(H2,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50515295 (CHEMBL4462477) Show SMILES CCCCCCc1cnc2c(N)nccn12 Show InChI InChI=1S/C12H18N4/c1-2-3-4-5-6-10-9-15-12-11(13)14-7-8-16(10)12/h7-9H,2-6H2,1H3,(H2,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...				J Med Chem 62: 7015-7031 (2019) Article DOI: 10.1021/acs.jmedchem.9b00411 BindingDB Entry DOI: 10.7270/Q2HX1H1M
					More data for this Ligand-Target Pair