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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM50515291'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM50515291
PNG
(CHEMBL4580838)
Show SMILES CC(C)Cc1cc2c(N)nc3ccccc3n2n1
Show InChI InChI=1S/C14H16N4/c1-9(2)7-10-8-13-14(15)16-11-5-3-4-6-12(11)18(13)17-10/h3-6,8-9H,7H2,1-2H3,(H2,15,16)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universit£ de Montpellier

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR7 expressed in HEK-blue cells assessed as inhibition of CL264-induced NFkappaB activation after 24 hrs using qunati-b...

J Med Chem 62: 7015-7031 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00411
BindingDB Entry DOI: 10.7270/Q2HX1H1M
More data for this
Ligand-Target Pair