Found 44 hits with Last Name = 'enthoven' and Initial = 'm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375439
(CHEMBL410304)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C)C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C34H37NO2/c1-33(32(37)23-9-10-23)16-15-30-28-13-11-24-18-26(36)12-14-27(24)31(28)29(19-34(30,33)2)22-7-5-21(6-8-22)25-4-3-17-35-20-25/h3-8,17-18,20,23,28-30H,9-16,19H2,1-2H3/t28-,29+,30-,33+,34-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375423
(ASOPRISNIL)Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375424
(ULIPRISTAL ACETATE | Ulipristal)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]2(OC(C)=O)C(C)=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:29,36| Show InChI InChI=1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1-5H3/t25-,26+,27-,29-,30-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375445
(CHEMBL445946)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]22CCCC2=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:28,35| Show InChI InChI=1S/C30H37NO2/c1-29-18-25(19-6-9-21(10-7-19)31(2)3)28-23-13-11-22(32)17-20(23)8-12-24(28)26(29)14-16-30(29)15-4-5-27(30)33/h6-7,9-10,17,24-26H,4-5,8,11-16,18H2,1-3H3/t24-,25+,26-,29-,30+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation relative to Org 31710 |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375444
(CHEMBL258861)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3[C@@H]12 |t:28| Show InChI InChI=1S/C30H39NO2/c1-19-14-16-33-30(19)15-13-27-25-11-7-21-17-23(32)10-12-24(21)28(25)26(18-29(27,30)2)20-5-8-22(9-6-20)31(3)4/h5-6,8-9,17,24-28H,1,7,10-16,18H2,2-4H3/t24?,25-,26+,27-,28+,29-,30+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation relative to Org 31710 |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375438
(CHEMBL410923)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-16-30-28-13-11-24-17-26(36)12-14-27(24)31(28)29(18-34(30,2)32(20)33(37)23-9-10-23)22-7-5-21(6-8-22)25-4-3-15-35-19-25/h3-8,15,17,19-20,23,28-30,32H,9-14,16,18H2,1-2H3/t20-,28+,29-,30+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375425
(CHEMBL259879)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC21CCCC1=O)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C33H35NO2/c1-32-19-28(22-8-6-21(7-9-22)24-4-3-17-34-20-24)31-26-13-11-25(35)18-23(26)10-12-27(31)29(32)14-16-33(32)15-2-5-30(33)36/h3-4,6-9,17-18,20,27-29H,2,5,10-16,19H2,1H3/t27-,28+,29-,32-,33?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375440
(CHEMBL411522)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H37NO3/c1-34-18-28(21-5-3-20(4-6-21)24-10-16-31(38-2)35-19-24)32-26-13-11-25(36)17-23(26)9-12-27(32)29(34)14-15-30(34)33(37)22-7-8-22/h3-6,10,16-17,19,22,27-30H,7-9,11-15,18H2,1-2H3/t27-,28+,29-,30+,34-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375433
(CHEMBL258522)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(Cl)nc1 |c:14,t:7| Show InChI InChI=1S/C34H36ClNO2/c1-19-15-29-27-12-9-23-16-25(37)11-13-26(23)31(27)28(17-34(29,2)32(19)33(38)22-7-8-22)21-5-3-20(4-6-21)24-10-14-30(35)36-18-24/h3-6,10,14,16,18-19,22,27-29,32H,7-9,11-13,15,17H2,1-2H3/t19-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375441
(CHEMBL260330)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CCC22CCCC2=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H37NO3/c1-33-19-28(22-7-5-21(6-8-22)24-10-14-31(38-2)35-20-24)32-26-13-11-25(36)18-23(26)9-12-27(32)29(33)15-17-34(33)16-3-4-30(34)37/h5-8,10,14,18,20,27-29H,3-4,9,11-13,15-17,19H2,1-2H3/t27-,28+,29-,33-,34?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375442
(CHEMBL260764)Show SMILES CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:15,t:8| Show InChI InChI=1S/C35H39NO2/c1-3-21-18-31-29-14-12-25-17-27(37)13-15-28(25)32(29)30(19-35(31,2)33(21)34(38)24-10-11-24)23-8-6-22(7-9-23)26-5-4-16-36-20-26/h4-9,16-17,20-21,24,29-31,33H,3,10-15,18-19H2,1-2H3/t21-,29+,30-,31+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375437
(CHEMBL409661)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1C[C@@H](C=C)[C@@H]2C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C35H37NO2/c1-3-21-18-31-29-14-12-25-17-27(37)13-15-28(25)32(29)30(19-35(31,2)33(21)34(38)24-10-11-24)23-8-6-22(7-9-23)26-5-4-16-36-20-26/h3-9,16-17,20-21,24,29-31,33H,1,10-15,18-19H2,2H3/t21-,29+,30-,31+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375436
(CHEMBL260869)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](C[C@@H](C)[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:35,42| Show InChI InChI=1S/C35H39NO3/c1-20-16-30-28-13-10-24-17-26(37)12-14-27(24)32(28)29(18-35(30,2)33(20)34(38)23-8-9-23)22-6-4-21(5-7-22)25-11-15-31(39-3)36-19-25/h4-7,11,15,17,19-20,23,28-30,33H,8-10,12-14,16,18H2,1-3H3/t20-,28+,29-,30+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375443
(CHEMBL408424)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C33H35NO2/c1-33-18-28(21-6-4-20(5-7-21)24-3-2-16-34-19-24)31-26-13-11-25(35)17-23(26)10-12-27(31)29(33)14-15-30(33)32(36)22-8-9-22/h2-7,16-17,19,22,27-30H,8-15,18H2,1H3/t27-,28+,29-,30+,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375434
(CHEMBL407371)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](C[C@@H](C=C)[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C36H39NO3/c1-4-21-18-31-29-14-11-25-17-27(38)13-15-28(25)33(29)30(19-36(31,2)34(21)35(39)24-9-10-24)23-7-5-22(6-8-23)26-12-16-32(40-3)37-20-26/h4-8,12,16-17,20-21,24,29-31,34H,1,9-11,13-15,18-19H2,2-3H3/t21-,29+,30-,31+,34-,36+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375427
(CHEMBL411086)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnccn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-15-28-26-11-9-23-16-24(36)10-12-25(23)30(26)27(17-33(28,2)31(19)32(37)22-7-8-22)20-3-5-21(6-4-20)29-18-34-13-14-35-29/h3-6,13-14,16,18-19,22,26-28,31H,7-12,15,17H2,1-2H3/t19-,26+,27-,28+,31-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375430
(CHEMBL409905)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccncc1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-17-30-28-11-9-25-18-26(36)10-12-27(25)31(28)29(19-34(30,2)32(20)33(37)24-7-8-24)23-5-3-21(4-6-23)22-13-15-35-16-14-22/h3-6,13-16,18,20,24,28-30,32H,7-12,17,19H2,1-2H3/t20-,28+,29-,30+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375426
(CHEMBL268788)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnc2ccccc2c1 |c:14,t:7| Show InChI InChI=1S/C38H39NO2/c1-22-17-33-31-15-13-26-19-29(40)14-16-30(26)35(31)32(20-38(33,2)36(22)37(41)25-11-12-25)24-9-7-23(8-10-24)28-18-27-5-3-4-6-34(27)39-21-28/h3-10,18-19,21-22,25,31-33,36H,11-17,20H2,1-2H3/t22-,31+,32-,33+,36-,38+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.14 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375428
(CHEMBL411063)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ncccn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-16-28-26-12-10-23-17-24(36)11-13-25(23)29(26)27(18-33(28,2)30(19)31(37)21-6-7-21)20-4-8-22(9-5-20)32-34-14-3-15-35-32/h3-5,8-9,14-15,17,19,21,26-28,30H,6-7,10-13,16,18H2,1-2H3/t19-,26+,27-,28+,30-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.25 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375429
(CHEMBL438593)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-16-28-26-13-11-23-17-24(36)12-14-25(23)30(26)27(18-33(28,2)31(19)32(37)22-9-10-22)20-5-7-21(8-6-20)29-4-3-15-34-35-29/h3-8,15,17,19,22,26-28,31H,9-14,16,18H2,1-2H3/t19-,26+,27-,28+,31-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.64 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375435
(CHEMBL406439)Show SMILES CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(OC)nc1 |c:15,t:8| Show InChI InChI=1S/C36H41NO3/c1-4-21-18-31-29-14-11-25-17-27(38)13-15-28(25)33(29)30(19-36(31,2)34(21)35(39)24-9-10-24)23-7-5-22(6-8-23)26-12-16-32(40-3)37-20-26/h5-8,12,16-17,20-21,24,29-31,34H,4,9-11,13-15,18-19H2,1-3H3/t21-,29+,30-,31+,34-,36+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.89 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375432
(CHEMBL258521)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(F)nc1 |c:14,t:7| Show InChI InChI=1S/C34H36FNO2/c1-19-15-29-27-12-9-23-16-25(37)11-13-26(23)31(27)28(17-34(29,2)32(19)33(38)22-7-8-22)21-5-3-20(4-6-21)24-10-14-30(35)36-18-24/h3-6,10,14,16,18-19,22,27-29,32H,7-9,11-13,15,17H2,1-2H3/t19-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.48 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375431
(CHEMBL261650)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccccn1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-17-29-27-14-12-24-18-25(36)13-15-26(24)31(27)28(19-34(29,2)32(20)33(37)23-10-11-23)21-6-8-22(9-7-21)30-5-3-4-16-35-30/h3-9,16,18,20,23,27-29,32H,10-15,17,19H2,1-2H3/t20-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14.8 | n/a | n/a | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375427
(CHEMBL411086)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnccn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-15-28-26-11-9-23-16-24(36)10-12-25(23)30(26)27(17-33(28,2)31(19)32(37)22-7-8-22)20-3-5-21(6-4-20)29-18-34-13-14-35-29/h3-6,13-14,16,18-19,22,26-28,31H,7-12,15,17H2,1-2H3/t19-,26+,27-,28+,31-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.13 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375426
(CHEMBL268788)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnc2ccccc2c1 |c:14,t:7| Show InChI InChI=1S/C38H39NO2/c1-22-17-33-31-15-13-26-19-29(40)14-16-30(26)35(31)32(20-38(33,2)36(22)37(41)25-11-12-25)24-9-7-23(8-10-24)28-18-27-5-3-4-6-34(27)39-21-28/h3-10,18-19,21-22,25,31-33,36H,11-17,20H2,1-2H3/t22-,31+,32-,33+,36-,38+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375425
(CHEMBL259879)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC21CCCC1=O)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C33H35NO2/c1-32-19-28(22-8-6-21(7-9-22)24-4-3-17-34-20-24)31-26-13-11-25(35)18-23(26)10-12-27(31)29(32)14-16-33(32)15-2-5-30(33)36/h3-4,6-9,17-18,20,27-29H,2,5,10-16,19H2,1H3/t27-,28+,29-,32-,33?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375442
(CHEMBL260764)Show SMILES CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:15,t:8| Show InChI InChI=1S/C35H39NO2/c1-3-21-18-31-29-14-12-25-17-27(37)13-15-28(25)32(29)30(19-35(31,2)33(21)34(38)24-10-11-24)23-8-6-22(7-9-23)26-5-4-16-36-20-26/h4-9,16-17,20-21,24,29-31,33H,3,10-15,18-19H2,1-2H3/t21-,29+,30-,31+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375443
(CHEMBL408424)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C33H35NO2/c1-33-18-28(21-6-4-20(5-7-21)24-3-2-16-34-19-24)31-26-13-11-25(35)17-23(26)10-12-27(31)29(33)14-15-30(33)32(36)22-8-9-22/h2-7,16-17,19,22,27-30H,8-15,18H2,1H3/t27-,28+,29-,30+,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375424
(ULIPRISTAL ACETATE | Ulipristal)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]2(OC(C)=O)C(C)=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:29,36| Show InChI InChI=1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1-5H3/t25-,26+,27-,29-,30-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375423
(ASOPRISNIL)Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| MMDB
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375428
(CHEMBL411063)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ncccn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-16-28-26-12-10-23-17-24(36)11-13-25(23)29(26)27(18-33(28,2)30(19)31(37)21-6-7-21)20-4-8-22(9-5-20)32-34-14-3-15-35-32/h3-5,8-9,14-15,17,19,21,26-28,30H,6-7,10-13,16,18H2,1-2H3/t19-,26+,27-,28+,30-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.54 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375441
(CHEMBL260330)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CCC22CCCC2=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H37NO3/c1-33-19-28(22-7-5-21(6-8-22)24-10-14-31(38-2)35-20-24)32-26-13-11-25(36)18-23(26)9-12-27(32)29(33)15-17-34(33)16-3-4-30(34)37/h5-8,10,14,18,20,27-29H,3-4,9,11-13,15-17,19H2,1-2H3/t27-,28+,29-,33-,34?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375440
(CHEMBL411522)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H37NO3/c1-34-18-28(21-5-3-20(4-6-21)24-10-16-31(38-2)35-19-24)32-26-13-11-25(36)17-23(26)9-12-27(32)29(34)14-15-30(34)33(37)22-7-8-22/h3-6,10,16-17,19,22,27-30H,7-9,11-15,18H2,1-2H3/t27-,28+,29-,30+,34-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375439
(CHEMBL410304)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C)C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C34H37NO2/c1-33(32(37)23-9-10-23)16-15-30-28-13-11-24-18-26(36)12-14-27(24)31(28)29(19-34(30,33)2)22-7-5-21(6-8-22)25-4-3-17-35-20-25/h3-8,17-18,20,23,28-30H,9-16,19H2,1-2H3/t28-,29+,30-,33+,34-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375438
(CHEMBL410923)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-16-30-28-13-11-24-17-26(36)12-14-27(24)31(28)29(18-34(30,2)32(20)33(37)23-9-10-23)22-7-5-21(6-8-22)25-4-3-15-35-19-25/h3-8,15,17,19-20,23,28-30,32H,9-14,16,18H2,1-2H3/t20-,28+,29-,30+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375437
(CHEMBL409661)Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1C[C@@H](C=C)[C@@H]2C(=O)C1CC1)c1ccc(cc1)-c1cccnc1 |c:4,10| Show InChI InChI=1S/C35H37NO2/c1-3-21-18-31-29-14-12-25-17-27(37)13-15-28(25)32(29)30(19-35(31,2)33(21)34(38)24-10-11-24)23-8-6-22(7-9-23)26-5-4-16-36-20-26/h3-9,16-17,20-21,24,29-31,33H,1,10-15,18-19H2,2H3/t21-,29+,30-,31+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375436
(CHEMBL260869)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](C[C@@H](C)[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:35,42| Show InChI InChI=1S/C35H39NO3/c1-20-16-30-28-13-10-24-17-26(37)12-14-27(24)32(28)29(18-35(30,2)33(20)34(38)23-8-9-23)22-6-4-21(5-7-22)25-11-15-31(39-3)36-19-25/h4-7,11,15,17,19-20,23,28-30,33H,8-10,12-14,16,18H2,1-3H3/t20-,28+,29-,30+,33-,35+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375435
(CHEMBL406439)Show SMILES CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(OC)nc1 |c:15,t:8| Show InChI InChI=1S/C36H41NO3/c1-4-21-18-31-29-14-11-25-17-27(38)13-15-28(25)33(29)30(19-36(31,2)34(21)35(39)24-9-10-24)23-7-5-22(6-8-23)26-12-16-32(40-3)37-20-26/h5-8,12,16-17,20-21,24,29-31,34H,4,9-11,13-15,18-19H2,1-3H3/t21-,29+,30-,31+,34-,36+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375434
(CHEMBL407371)Show SMILES COc1ccc(cn1)-c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](C[C@@H](C=C)[C@@H]2C(=O)C2CC2)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C36H39NO3/c1-4-21-18-31-29-14-11-25-17-27(38)13-15-28(25)33(29)30(19-36(31,2)34(21)35(39)24-9-10-24)23-7-5-22(6-8-23)26-12-16-32(40-3)37-20-26/h4-8,12,16-17,20-21,24,29-31,34H,1,9-11,13-15,18-19H2,2-3H3/t21-,29+,30-,31+,34-,36+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375433
(CHEMBL258522)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(Cl)nc1 |c:14,t:7| Show InChI InChI=1S/C34H36ClNO2/c1-19-15-29-27-12-9-23-16-25(37)11-13-26(23)31(27)28(17-34(29,2)32(19)33(38)22-7-8-22)21-5-3-20(4-6-21)24-10-14-30(35)36-18-24/h3-6,10,14,16,18-19,22,27-29,32H,7-9,11-13,15,17H2,1-2H3/t19-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375432
(CHEMBL258521)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccc(F)nc1 |c:14,t:7| Show InChI InChI=1S/C34H36FNO2/c1-19-15-29-27-12-9-23-16-25(37)11-13-26(23)31(27)28(17-34(29,2)32(19)33(38)22-7-8-22)21-5-3-20(4-6-21)24-10-14-30(35)36-18-24/h3-6,10,14,16,18-19,22,27-29,32H,7-9,11-13,15,17H2,1-2H3/t19-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375429
(CHEMBL438593)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cccnn1 |c:14,t:7| Show InChI InChI=1S/C33H36N2O2/c1-19-16-28-26-13-11-23-17-24(36)12-14-25(23)30(26)27(18-33(28,2)31(19)32(37)22-9-10-22)20-5-7-21(8-6-20)29-4-3-15-34-35-29/h3-8,15,17,19,22,26-28,31H,9-14,16,18H2,1-2H3/t19-,26+,27-,28+,31-,33+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375430
(CHEMBL409905)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccncc1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-17-30-28-11-9-25-18-26(36)10-12-27(25)31(28)29(19-34(30,2)32(20)33(37)24-7-8-24)23-5-3-21(4-6-23)22-13-15-35-16-14-22/h3-6,13-16,18,20,24,28-30,32H,7-12,17,19H2,1-2H3/t20-,28+,29-,30+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50375431
(CHEMBL261650)Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1ccccn1 |c:14,t:7| Show InChI InChI=1S/C34H37NO2/c1-20-17-29-27-14-12-24-18-25(36)13-15-26(24)31(27)28(19-34(29,2)32(20)33(37)23-10-11-23)21-6-8-22(9-7-21)30-5-3-4-16-35-30/h3-9,16,18,20,23,27-29,32H,10-15,17,19H2,1-2H3/t20-,27+,28-,29+,32-,34+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
NV Organon
Curated by ChEMBL
| Assay Description
Agonist activity at human PRB expressed in CHO cells |
Bioorg Med Chem 16: 2753-63 (2008)
Article DOI: 10.1016/j.bmc.2008.01.010
BindingDB Entry DOI: 10.7270/Q2Z89D9G |
More data for this
Ligand-Target Pair | |
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