Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50375445'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375445 (CHEMBL445946) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]22CCCC2=O)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:28,35| Show InChI InChI=1S/C30H37NO2/c1-29-18-25(19-6-9-21(10-7-19)31(2)3)28-23-13-11-22(32)17-20(23)8-12-24(28)26(29)14-16-30(29)15-4-5-27(30)33/h6-7,9-10,17,24-26H,4-5,8,11-16,18H2,1-3H3/t24-,25+,26-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
NV Organon Curated by ChEMBL					Assay Description Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation relative to Org 31710				Bioorg Med Chem 16: 2753-63 (2008) Article DOI: 10.1016/j.bmc.2008.01.010 BindingDB Entry DOI: 10.7270/Q2Z89D9G
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