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Compile Data Set for Download or QSAR

Found 132 hits with Last Name = 'fantasia' and Initial = 'sm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233803
PNG
(US9353081, 1 | US9353081, 2 | US9353081, 3)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)
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n/an/an/an/a 30n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233803
PNG
(US9353081, 1 | US9353081, 2 | US9353081, 3)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)
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n/an/an/an/a 1.02E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233803
PNG
(US9353081, 1 | US9353081, 2 | US9353081, 3)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)
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n/an/an/an/a 14n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233806
PNG
(US9353081, 3-1)
Show SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O2/c1-3-21(26)24-19-6-4-5-16-17(12-23-13-18(16)19)14-7-9-20-15(11-14)8-10-22(27)25(20)2/h7,9,11-13,19H,3-6,8,10H2,1-2H3,(H,24,26)/t19-/m1/s1
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n/an/an/an/a 14n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233807
PNG
(US9353081, 4 | US9353081, 5 | US9353081, 6)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H25N3O3S/c1-3-28(26,27)23-19-6-4-5-16-17(12-22-13-18(16)19)14-7-9-20-15(11-14)8-10-21(25)24(20)2/h7,9,11-13,19,23H,3-6,8,10H2,1-2H3
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n/an/an/an/a 97n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233807
PNG
(US9353081, 4 | US9353081, 5 | US9353081, 6)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H25N3O3S/c1-3-28(26,27)23-19-6-4-5-16-17(12-22-13-18(16)19)14-7-9-20-15(11-14)8-10-21(25)24(20)2/h7,9,11-13,19,23H,3-6,8,10H2,1-2H3
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n/an/an/an/a 1.29E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233807
PNG
(US9353081, 4 | US9353081, 5 | US9353081, 6)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H25N3O3S/c1-3-28(26,27)23-19-6-4-5-16-17(12-22-13-18(16)19)14-7-9-20-15(11-14)8-10-21(25)24(20)2/h7,9,11-13,19,23H,3-6,8,10H2,1-2H3
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n/an/an/an/a 48n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233810
PNG
(US9353081, 7 | US9353081, 9)
Show SMILES CCC(=O)NC1CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H23N3O2/c1-3-20(25)23-18-7-6-15-16(11-22-12-17(15)18)13-4-8-19-14(10-13)5-9-21(26)24(19)2/h4,8,10-12,18H,3,5-7,9H2,1-2H3,(H,23,25)
PDB

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n/an/an/an/a 12n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233810
PNG
(US9353081, 7 | US9353081, 9)
Show SMILES CCC(=O)NC1CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H23N3O2/c1-3-20(25)23-18-7-6-15-16(11-22-12-17(15)18)13-4-8-19-14(10-13)5-9-21(26)24(19)2/h4,8,10-12,18H,3,5-7,9H2,1-2H3,(H,23,25)
PDB

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n/an/an/an/a 13n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233812
PNG
(US9353081, 10)
Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C20H23N3O3S/c1-3-27(25,26)22-18-7-6-15-16(11-21-12-17(15)18)13-4-8-19-14(10-13)5-9-20(24)23(19)2/h4,8,10-12,18,22H,3,5-7,9H2,1-2H3
PDB

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n/an/an/an/a 59n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233813
PNG
(US9353081, 11)
Show SMILES CN1C(=O)CCc2cc(ccc12)-c1cncc2N(CCNC(=O)OC(C)(C)C)CCCc12
Show InChI InChI=1S/C25H32N4O3/c1-25(2,3)32-24(31)27-11-13-29-12-5-6-19-20(15-26-16-22(19)29)17-7-9-21-18(14-17)8-10-23(30)28(21)4/h7,9,14-16H,5-6,8,10-13H2,1-4H3,(H,27,31)
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n/an/an/an/a 23n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233814
PNG
(US9353081, 12)
Show SMILES CN1C(=O)CCc2cc(ccc12)-c1cncc2N(CCN)CCCc12
Show InChI InChI=1S/C20H24N4O/c1-23-18-6-4-14(11-15(18)5-7-20(23)25)17-12-22-13-19-16(17)3-2-9-24(19)10-8-21/h4,6,11-13H,2-3,5,7-10,21H2,1H3
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n/an/an/an/a 4n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233815
PNG
(US9353081, 13)
Show SMILES CCC(=O)NCCN1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C23H28N4O2/c1-3-22(28)25-10-12-27-11-4-5-18-19(14-24-15-21(18)27)16-6-8-20-17(13-16)7-9-23(29)26(20)2/h6,8,13-15H,3-5,7,9-12H2,1-2H3,(H,25,28)
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n/an/an/an/a 14n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233816
PNG
(US9353081, 14)
Show SMILES CCS(=O)(=O)NCCN1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H28N4O3S/c1-3-30(28,29)24-10-12-26-11-4-5-18-19(14-23-15-21(18)26)16-6-8-20-17(13-16)7-9-22(27)25(20)2/h6,8,13-15,24H,3-5,7,9-12H2,1-2H3
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n/an/an/an/a 11n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233817
PNG
(US9353081, 15)
Show SMILES CC(O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)
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n/an/an/an/a 77.3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233818
PNG
(US9353081, 16 | US9353081, 18 | US9353081, 19)
Show SMILES C[C@@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m1/s1
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n/an/an/an/a 30.8n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233819
PNG
(US9353081, 17 | US9353081, 20 | US9353081, 21)
Show SMILES C[C@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m0/s1
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n/an/an/an/a 31.6n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233818
PNG
(US9353081, 16 | US9353081, 18 | US9353081, 19)
Show SMILES C[C@@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m1/s1
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n/an/an/an/a 27.9n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233818
PNG
(US9353081, 16 | US9353081, 18 | US9353081, 19)
Show SMILES C[C@@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m1/s1
PDB

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n/an/an/an/a 493n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233819
PNG
(US9353081, 17 | US9353081, 20 | US9353081, 21)
Show SMILES C[C@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m0/s1
PDB

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n/an/an/an/a 823n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233819
PNG
(US9353081, 17 | US9353081, 20 | US9353081, 21)
Show SMILES C[C@H](O)C(=O)NC1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H25N3O3/c1-13(26)22(28)24-19-5-3-4-16-17(11-23-12-18(16)19)14-6-8-20-15(10-14)7-9-21(27)25(20)2/h6,8,10-13,19,26H,3-5,7,9H2,1-2H3,(H,24,28)/t13-,19?/m0/s1
PDB

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n/an/an/an/a 28n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233824
PNG
(US9353081, 22 | US9353081, 23 | US9353081, 24)
Show SMILES CCC(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C21H22FN3O2/c1-3-20(26)24-18-6-5-13-15(10-23-11-16(13)18)14-8-12-4-7-21(27)25(2)19(12)9-17(14)22/h8-11,18H,3-7H2,1-2H3,(H,24,26)
PDB

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n/an/an/an/a 10.2n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233824
PNG
(US9353081, 22 | US9353081, 23 | US9353081, 24)
Show SMILES CCC(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C21H22FN3O2/c1-3-20(26)24-18-6-5-13-15(10-23-11-16(13)18)14-8-12-4-7-21(27)25(2)19(12)9-17(14)22/h8-11,18H,3-7H2,1-2H3,(H,24,26)
PDB

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n/an/an/an/a 1.38E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233824
PNG
(US9353081, 22 | US9353081, 23 | US9353081, 24)
Show SMILES CCC(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C21H22FN3O2/c1-3-20(26)24-18-6-5-13-15(10-23-11-16(13)18)14-8-12-4-7-21(27)25(2)19(12)9-17(14)22/h8-11,18H,3-7H2,1-2H3,(H,24,26)
PDB

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n/an/an/an/a 3.80n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233826
PNG
(US9353081, 25 | US9353081, 26 | US9353081, 27)
Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C20H22FN3O3S/c1-3-28(26,27)23-18-6-5-13-15(10-22-11-16(13)18)14-8-12-4-7-20(25)24(2)19(12)9-17(14)21/h8-11,18,23H,3-7H2,1-2H3
PDB

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n/an/an/an/a 33.4n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233826
PNG
(US9353081, 25 | US9353081, 26 | US9353081, 27)
Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C20H22FN3O3S/c1-3-28(26,27)23-18-6-5-13-15(10-22-11-16(13)18)14-8-12-4-7-20(25)24(2)19(12)9-17(14)21/h8-11,18,23H,3-7H2,1-2H3
PDB

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n/an/an/an/a 4.55E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233826
PNG
(US9353081, 25 | US9353081, 26 | US9353081, 27)
Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C20H22FN3O3S/c1-3-28(26,27)23-18-6-5-13-15(10-22-11-16(13)18)14-8-12-4-7-20(25)24(2)19(12)9-17(14)21/h8-11,18,23H,3-7H2,1-2H3
PDB

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n/an/an/an/a 11.2n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233828
PNG
(US9353081, 28 | US9353081, 29 | US9353081, 30)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C22H24FN3O2/c1-3-21(27)25-19-6-4-5-14-16(11-24-12-17(14)19)15-9-13-7-8-22(28)26(2)20(13)10-18(15)23/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 74.9n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233828
PNG
(US9353081, 28 | US9353081, 29 | US9353081, 30)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C22H24FN3O2/c1-3-21(27)25-19-6-4-5-14-16(11-24-12-17(14)19)15-9-13-7-8-22(28)26(2)20(13)10-18(15)23/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 1.79E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233828
PNG
(US9353081, 28 | US9353081, 29 | US9353081, 30)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C22H24FN3O2/c1-3-21(27)25-19-6-4-5-14-16(11-24-12-17(14)19)15-9-13-7-8-22(28)26(2)20(13)10-18(15)23/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 30n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233830
PNG
(US9353081, 31 | US9353081, 32)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C21H24FN3O3S/c1-3-29(27,28)24-19-6-4-5-14-16(11-23-12-17(14)19)15-9-13-7-8-21(26)25(2)20(13)10-18(15)22/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 1.04E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233830
PNG
(US9353081, 31 | US9353081, 32)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F
Show InChI InChI=1S/C21H24FN3O3S/c1-3-29(27,28)24-19-6-4-5-14-16(11-23-12-17(14)19)15-9-13-7-8-21(26)25(2)20(13)10-18(15)22/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 78.2n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233831
PNG
(US9353081, 33 | US9353081, 40 | US9353081, 41)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H24ClN3O2/c1-3-20(27)25-19-6-4-5-15-16(11-24-12-17(15)19)14-9-13-7-8-21(28)26(2)22(13)18(23)10-14/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 79.8n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233832
PNG
(US9353081, 34)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1Cl
Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-14-16(11-23-12-17(14)19)15-9-13-7-8-21(26)25(2)20(13)10-18(15)22/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 386n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233833
PNG
(US9353081, 35)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1Cl
Show InChI InChI=1S/C22H24ClN3O2/c1-3-21(27)25-19-6-4-5-14-16(11-24-12-17(14)19)15-9-13-7-8-22(28)26(2)20(13)10-18(15)23/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 1.77E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233834
PNG
(US9353081, 36)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(F)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H24FN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 239n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233835
PNG
(US9353081, 37 | US9353081, 38 | US9353081, 39)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 199n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233835
PNG
(US9353081, 37 | US9353081, 38 | US9353081, 39)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 422n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233835
PNG
(US9353081, 37 | US9353081, 38 | US9353081, 39)
Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3
PDB

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n/an/an/an/a 130n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233831
PNG
(US9353081, 33 | US9353081, 40 | US9353081, 41)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H24ClN3O2/c1-3-20(27)25-19-6-4-5-15-16(11-24-12-17(15)19)14-9-13-7-8-21(28)26(2)22(13)18(23)10-14/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 126n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233831
PNG
(US9353081, 33 | US9353081, 40 | US9353081, 41)
Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1
Show InChI InChI=1S/C22H24ClN3O2/c1-3-20(27)25-19-6-4-5-15-16(11-24-12-17(15)19)14-9-13-7-8-21(28)26(2)22(13)18(23)10-14/h9-12,19H,3-8H2,1-2H3,(H,25,27)
PDB

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n/an/an/an/a 16.6n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233838
PNG
(US9353081, 42)
Show SMILES CCC(=O)N[C@H]1[C@H](C)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C23H27N3O2/c1-4-21(27)25-23-14(2)5-8-17-18(12-24-13-19(17)23)15-6-9-20-16(11-15)7-10-22(28)26(20)3/h6,9,11-14,23H,4-5,7-8,10H2,1-3H3,(H,25,27)/t14-,23+/m1/s1
PDB

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n/an/an/an/a 14.5n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233839
PNG
(US9353081, 43)
Show SMILES CCC(=O)N[C@@H]1[C@H](C)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r|
Show InChI InChI=1S/C23H26FN3O2/c1-4-21(28)26-23-13(2)5-7-15-17(11-25-12-18(15)23)16-9-14-6-8-22(29)27(3)20(14)10-19(16)24/h9-13,23H,4-8H2,1-3H3,(H,26,28)/t13-,23-/m1/s1
PDB

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n/an/an/an/a 452n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233840
PNG
(US9353081, 44)
Show SMILES CCC(=O)N[C@@H]1[C@@H](C)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r|
Show InChI InChI=1S/C23H26FN3O2/c1-4-21(28)26-23-13(2)5-7-15-17(11-25-12-18(15)23)16-9-14-6-8-22(29)27(3)20(14)10-19(16)24/h9-13,23H,4-8H2,1-3H3,(H,26,28)/t13-,23+/m0/s1
PDB

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n/an/an/an/a 529n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233841
PNG
(US9353081, 45)
Show SMILES CCC(=O)N[C@H]1[C@H](C)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r|
Show InChI InChI=1S/C23H26FN3O2/c1-4-21(28)26-23-13(2)5-7-15-17(11-25-12-18(15)23)16-9-14-6-8-22(29)27(3)20(14)10-19(16)24/h9-13,23H,4-8H2,1-3H3,(H,26,28)/t13-,23+/m1/s1
PDB

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n/an/an/an/a 54.9n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233842
PNG
(US9353081, 46)
Show SMILES CCC(=O)N[C@@H]1[C@H](C)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C23H27N3O2/c1-4-21(27)25-23-14(2)5-8-17-18(12-24-13-19(17)23)15-6-9-20-16(11-15)7-10-22(28)26(20)3/h6,9,11-14,23H,4-5,7-8,10H2,1-3H3,(H,25,27)/t14-,23-/m1/s1
PDB

UniProtKB/SwissProt

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n/an/an/an/a 467n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233843
PNG
(US9353081, 47)
Show SMILES CCC(=O)N[C@@H]1[C@@H](C)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C23H27N3O2/c1-4-21(27)25-23-14(2)5-8-17-18(12-24-13-19(17)23)15-6-9-20-16(11-15)7-10-22(28)26(20)3/h6,9,11-14,23H,4-5,7-8,10H2,1-3H3,(H,25,27)/t14-,23+/m0/s1
PDB

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n/an/an/an/a 1.82E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233844
PNG
(US9353081, 48)
Show SMILES CCC(=O)N[C@H]1[C@@H](C)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r|
Show InChI InChI=1S/C23H26FN3O2/c1-4-21(28)26-23-13(2)5-7-15-17(11-25-12-18(15)23)16-9-14-6-8-22(29)27(3)20(14)10-19(16)24/h9-13,23H,4-8H2,1-3H3,(H,26,28)/t13-,23-/m0/s1
PDB

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n/an/an/an/a 26.1n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233845
PNG
(US9353081, 49)
Show SMILES CCC(=O)N[C@H]1[C@@H](C)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C23H27N3O2/c1-4-21(27)25-23-14(2)5-8-17-18(12-24-13-19(17)23)15-6-9-20-16(11-15)7-10-22(28)26(20)3/h6,9,11-14,23H,4-5,7-8,10H2,1-3H3,(H,25,27)/t14-,23-/m0/s1
PDB

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n/an/an/an/a 44.2n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))
BDBM233846
PNG
(US9353081, 50)
Show SMILES CCC(=O)N[C@@H]1[C@@H](F)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r|
Show InChI InChI=1S/C22H24FN3O2/c1-3-20(27)25-22-17-12-24-11-16(15(17)6-7-18(22)23)13-4-8-19-14(10-13)5-9-21(28)26(19)2/h4,8,10-12,18,22H,3,5-7,9H2,1-2H3,(H,25,27)/t18-,22-/m0/s1
PDB

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n/an/an/an/a 4.32E+3n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...


US Patent US9353081 (2016)


BindingDB Entry DOI: 10.7270/Q2ZW1JT1
More data for this
Ligand-Target Pair
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