Compile Data Set for Download or QSAR

Found 39 hits with Last Name = 'finan' and Initial = 'pm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156294 (CHEMBL3781415) Show SMILES Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H17N7/c18-16-21-10-13(15(23-16)9-11-1-2-11)14-5-8-20-17(24-14)22-12-3-6-19-7-4-12/h3-8,10-11H,1-2,9H2,(H2,18,21,23)(H,19,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156296 (CHEMBL3781466) Show SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7O/c1-21(2,29)13-25-19-24-12-16(18(28-19)11-14-3-4-14)17-7-10-23-20(27-17)26-15-5-8-22-9-6-15/h5-10,12,14,29H,3-4,11,13H2,1-2H3,(H,24,25,28)(H,22,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156294 (CHEMBL3781415) Show SMILES Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H17N7/c18-16-21-10-13(15(23-16)9-11-1-2-11)14-5-8-20-17(24-14)22-12-3-6-19-7-4-12/h3-8,10-11H,1-2,9H2,(H2,18,21,23)(H,19,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156296 (CHEMBL3781466) Show SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7O/c1-21(2,29)13-25-19-24-12-16(18(28-19)11-14-3-4-14)17-7-10-23-20(27-17)26-15-5-8-22-9-6-15/h5-10,12,14,29H,3-4,11,13H2,1-2H3,(H,24,25,28)(H,22,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156298 (CHEMBL3781926) Show SMILES CC(C)(C)Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7/c1-21(2,3)28-20-24-13-16(18(27-20)12-14-4-5-14)17-8-11-23-19(26-17)25-15-6-9-22-10-7-15/h6-11,13-14H,4-5,12H2,1-3H3,(H,24,27,28)(H,22,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156295 (CHEMBL3781615) Show SMILES C(Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1)c1ccccc1 Show InChI InChI=1S/C24H23N7/c1-2-4-18(5-3-1)15-27-23-28-16-20(22(31-23)14-17-6-7-17)21-10-13-26-24(30-21)29-19-8-11-25-12-9-19/h1-5,8-13,16-17H,6-7,14-15H2,(H,27,28,31)(H,25,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156297 (CHEMBL3780339) Show SMILES CC(C)(C)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C22H27N7/c1-22(2,3)14-26-20-25-13-17(19(29-20)12-15-4-5-15)18-8-11-24-21(28-18)27-16-6-9-23-10-7-16/h6-11,13,15H,4-5,12,14H2,1-3H3,(H,25,26,29)(H,23,24,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156300 (CHEMBL3781634) Show SMILES COc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H18N6O/c1-25-18-21-11-14(16(24-18)10-12-2-3-12)15-6-9-20-17(23-15)22-13-4-7-19-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156337 (CHEMBL3781236) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccc(OC)cc2)n1 Show InChI InChI=1S/C20H22N6O/c1-21-19-23-12-16(18(26-19)11-13-3-4-13)17-9-10-22-20(25-17)24-14-5-7-15(27-2)8-6-14/h5-10,12-13H,3-4,11H2,1-2H3,(H,21,23,26)(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156338 (CHEMBL3782016) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2cnc3ccccc3c2)n1 Show InChI InChI=1S/C22H21N7/c1-23-21-26-13-17(20(29-21)10-14-6-7-14)19-8-9-24-22(28-19)27-16-11-15-4-2-3-5-18(15)25-12-16/h2-5,8-9,11-14H,6-7,10H2,1H3,(H,23,26,29)(H,24,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156301 (CHEMBL3781020) Show SMILES C(C1CC1)c1ncncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H16N6/c1-2-12(1)9-16-14(10-19-11-21-16)15-5-8-20-17(23-15)22-13-3-6-18-7-4-13/h3-8,10-12H,1-2,9H2,(H,18,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156299 (CHEMBL3780762) Show SMILES C(C1CC1)c1nc(NC2CCOCC2)ncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C22H25N7O/c1-2-15(1)13-20-18(14-25-22(29-20)27-17-6-11-30-12-7-17)19-5-10-24-21(28-19)26-16-3-8-23-9-4-16/h3-5,8-10,14-15,17H,1-2,6-7,11-13H2,(H,25,27,29)(H,23,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156299 (CHEMBL3780762) Show SMILES C(C1CC1)c1nc(NC2CCOCC2)ncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C22H25N7O/c1-2-15(1)13-20-18(14-25-22(29-20)27-17-6-11-30-12-7-17)19-5-10-24-21(28-19)26-16-3-8-23-9-4-16/h3-5,8-10,14-15,17H,1-2,6-7,11-13H2,(H,25,27,29)(H,23,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156336 (CHEMBL3780896) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C19H20N6/c1-20-18-22-12-15(17(25-18)11-13-7-8-13)16-9-10-21-19(24-16)23-14-5-3-2-4-6-14/h2-6,9-10,12-13H,7-8,11H2,1H3,(H,20,22,25)(H,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156301 (CHEMBL3781020) Show SMILES C(C1CC1)c1ncncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H16N6/c1-2-12(1)9-16-14(10-19-11-21-16)15-5-8-20-17(23-15)22-13-3-6-18-7-4-13/h3-8,10-12H,1-2,9H2,(H,18,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156333 (CHEMBL3781964) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C18H24N6O/c1-19-17-21-11-14(16(24-17)10-12-2-3-12)15-4-7-20-18(23-15)22-13-5-8-25-9-6-13/h4,7,11-13H,2-3,5-6,8-10H2,1H3,(H,19,21,24)(H,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156332 (CHEMBL3780864) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](N)CC2)n1 |r,wU:21.23,wD:18.19,(-1.08,8.31,;-.01,7.7,;-0,6.16,;-1.34,5.39,;-1.33,3.85,;,3.08,;1.33,3.85,;2.67,3.09,;4,3.86,;5.46,3.82,;4.68,5.15,;1.33,5.39,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.67,-1.54,;2.66,-3.08,;1.33,-3.85,;1.32,-5.39,;2.65,-6.16,;2.65,-7.4,;3.99,-5.4,;4,-3.86,;1.33,.77,)| Show InChI InChI=1S/C19H27N7/c1-21-18-23-11-15(17(26-18)10-12-2-3-12)16-8-9-22-19(25-16)24-14-6-4-13(20)5-7-14/h8-9,11-14H,2-7,10,20H2,1H3,(H,21,23,26)(H,22,24,25)/t13-,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156297 (CHEMBL3780339) Show SMILES CC(C)(C)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C22H27N7/c1-22(2,3)14-26-20-25-13-17(19(29-20)12-15-4-5-15)18-8-11-24-21(28-18)27-16-6-9-23-10-7-16/h6-11,13,15H,4-5,12,14H2,1-3H3,(H,25,26,29)(H,23,24,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156298 (CHEMBL3781926) Show SMILES CC(C)(C)Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7/c1-21(2,3)28-20-24-13-16(18(27-20)12-14-4-5-14)17-8-11-23-19(26-17)25-15-6-9-22-10-7-15/h6-11,13-14H,4-5,12H2,1-3H3,(H,24,27,28)(H,22,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156296 (CHEMBL3781466) Show SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C21H25N7O/c1-21(2,29)13-25-19-24-12-16(18(28-19)11-14-3-4-14)17-7-10-23-20(27-17)26-15-5-8-22-9-6-15/h5-10,12,14,29H,3-4,11,13H2,1-2H3,(H,24,25,28)(H,22,23,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156294 (CHEMBL3781415) Show SMILES Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H17N7/c18-16-21-10-13(15(23-16)9-11-1-2-11)14-5-8-20-17(24-14)22-12-3-6-19-7-4-12/h3-8,10-11H,1-2,9H2,(H2,18,21,23)(H,19,20,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156334 (CHEMBL3780077) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(NC2CCCCC2)n1 Show InChI InChI=1S/C19H26N6/c1-20-18-22-12-15(17(25-18)11-13-7-8-13)16-9-10-21-19(24-16)23-14-5-3-2-4-6-14/h9-10,12-14H,2-8,11H2,1H3,(H,20,22,25)(H,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156295 (CHEMBL3781615) Show SMILES C(Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1)c1ccccc1 Show InChI InChI=1S/C24H23N7/c1-2-4-18(5-3-1)15-27-23-28-16-20(22(31-23)14-17-6-7-17)21-10-13-26-24(30-21)29-19-8-11-25-12-9-19/h1-5,8-13,16-17H,6-7,14-15H2,(H,27,28,31)(H,25,26,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI4Kbeta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156299 (CHEMBL3780762) Show SMILES C(C1CC1)c1nc(NC2CCOCC2)ncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C22H25N7O/c1-2-15(1)13-20-18(14-25-22(29-20)27-17-6-11-30-12-7-17)19-5-10-24-21(28-19)26-16-3-8-23-9-4-16/h3-5,8-10,14-15,17H,1-2,6-7,11-13H2,(H,25,27,29)(H,23,24,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50156335 (CHEMBL3781076) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(NCCCO)n1 Show InChI InChI=1S/C16H22N6O/c1-17-15-20-10-12(14(22-15)9-11-3-4-11)13-5-7-19-16(21-13)18-6-2-8-23/h5,7,10-11,23H,2-4,6,8-9H2,1H3,(H,17,20,22)(H,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assay				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156300 (CHEMBL3781634) Show SMILES COc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H18N6O/c1-25-18-21-11-14(16(24-18)10-12-2-3-12)15-6-9-20-17(23-15)22-13-4-7-19-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50156301 (CHEMBL3781020) Show SMILES C(C1CC1)c1ncncc1-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C17H16N6/c1-2-12(1)9-16-14(10-19-11-21-16)15-5-8-20-17(23-15)22-13-3-6-18-7-4-13/h3-8,10-12H,1-2,9H2,(H,18,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50156302 (CHEMBL3780029) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1 Show InChI InChI=1S/C18H19N7/c1-19-17-22-11-14(16(25-17)10-12-2-3-12)15-6-9-21-18(24-15)23-13-4-7-20-8-5-13/h4-9,11-12H,2-3,10H2,1H3,(H,19,22,25)(H,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50156293 (CHEMBL3781916) Show SMILES CNc1ncc(c(CC2CC2)n1)-c1ccnc(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:21.23,wD:18.19,(-9.3,9.74,;-9.31,8.51,;-7.98,7.73,;-6.64,8.49,;-5.31,7.71,;-5.32,6.17,;-6.66,5.41,;-6.67,3.87,;-8.01,3.11,;-8.71,1.83,;-9.47,3.17,;-7.99,6.19,;-3.99,5.4,;-2.65,6.16,;-1.32,5.39,;-1.33,3.85,;-2.66,3.08,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;2.4,-1.39,;1.33,.77,;,1.54,;-4,3.86,)| Show InChI InChI=1S/C19H26N6O/c1-20-18-22-11-15(17(25-18)10-12-2-3-12)16-8-9-21-19(24-16)23-13-4-6-14(26)7-5-13/h8-9,11-14,26H,2-7,10H2,1H3,(H,20,22,25)(H,21,23,24)/t13-,14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin)				ACS Med Chem Lett 7: 72-6 (2016) Article DOI: 10.1021/acsmedchemlett.5b00335 BindingDB Entry DOI: 10.7270/Q2K35WK6
					More data for this Ligand-Target Pair