Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrase (Human immunodeficiency virus 1) | BDBM23399 (4-{1-[(4-fluorophenyl)methyl]-1H-pyrrol-2-yl}-2,4-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM23399 (4-{1-[(4-fluorophenyl)methyl]-1H-pyrrol-2-yl}-2,4-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50190612 ((2Z)-4-[1-(4-fluoro-benzyl)-1H-pyrrol-2-yl]-2-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50115579 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50115579 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity in presence of exogenous cobalt ion | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50115579 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity in presence of exogenous cobalt ion | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50190612 ((2Z)-4-[1-(4-fluoro-benzyl)-1H-pyrrol-2-yl]-2-hydr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.87E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50125832 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50115579 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >3.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3' processing activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50125832 ((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Sassari Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity | J Med Chem 49: 4248-60 (2006) Article DOI: 10.1021/jm060193m BindingDB Entry DOI: 10.7270/Q2T15384 | |||||||||||
More data for this Ligand-Target Pair |