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Compile Data Set for Download or QSAR

Found 2 hits with Last Name = 'florence' and Initial = 'x'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11


(Homo sapiens (Human))
BDBM86248
PNG
(CAS_364-98-7 | NSC_3019 | diazoxide)
Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1|
Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/an/an/a 2.35E+4n/an/an/an/a



Universite de Liege

Curated by ChEMBL


Assay Description
Activation of human recombinant SUR1/Kir6.2 channel expressed in HEK293 cells assessed as increase in ionic current by whole cell patch clamp assay


J Med Chem 53: 147-54 (2010)


Article DOI: 10.1021/jm9010093
BindingDB Entry DOI: 10.7270/Q2C82B7T
More data for this
Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11


(Homo sapiens (Human))
BDBM50378565
PNG
(CHEMBL568795)
Show SMILES Clc1ccc2c(c1)N=C(NC1CCC1)NS2(=O)=O |t:8|
Show InChI InChI=1S/C11H12ClN3O2S/c12-7-4-5-10-9(6-7)14-11(15-18(10,16)17)13-8-2-1-3-8/h4-6,8H,1-3H2,(H2,13,14,15)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 80n/an/an/an/a



Universite de Liege

Curated by ChEMBL


Assay Description
Activation of human recombinant SUR1/Kir6.2 channel expressed in HEK293 cells assessed as increase in ionic current by whole cell patch clamp assay


J Med Chem 53: 147-54 (2010)


Article DOI: 10.1021/jm9010093
BindingDB Entry DOI: 10.7270/Q2C82B7T
More data for this
Ligand-Target Pair