Found 30 hits with Last Name = 'flores-morales' and Initial = 'v' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102746
(CHEMBL3343062)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C39H54O4/c1-34(2)21-23-39(33(41)42)24-22-37(6)27(28(39)25-34)14-15-30-36(5)19-18-31(35(3,4)29(36)17-20-38(30,37)7)43-32(40)16-13-26-11-9-8-10-12-26/h8-14,16,28-31H,15,17-25H2,1-7H3,(H,41,42)/b16-13+/t28-,29-,30+,31-,36-,37+,38+,39-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Mixed-type inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot method |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50158368
(CHEMBL3787288)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C)(C)C=C21)C(=O)OC |r,t:34| Show InChI InChI=1S/C31H48O3/c1-26(2)15-17-31(25(33)34-8)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(32)27(3,4)22(28)11-14-30(23,29)7/h19-20,22-23H,9-18H2,1-8H3/t20-,22+,23-,28+,29-,30-,31+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Competitive inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate by Lineweaver-Burk pl... |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102748
(CHEMBL3343064)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H52O3/c1-9-35-25-13-14-29(6)23(28(25,4)5)12-15-31(8)24(29)11-10-21-22-20-27(2,3)16-18-32(22,26(33)34)19-17-30(21,31)7/h10,22-25H,9,11-20H2,1-8H3,(H,33,34)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Non-competitive inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot method |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Mixed-type inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot method |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102748
(CHEMBL3343064)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H52O3/c1-9-35-25-13-14-29(6)23(28(25,4)5)12-15-31(8)24(29)11-10-21-22-20-27(2,3)16-18-32(22,26(33)34)19-17-30(21,31)7/h10,22-25H,9,11-20H2,1-8H3,(H,33,34)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102746
(CHEMBL3343062)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C39H54O4/c1-34(2)21-23-39(33(41)42)24-22-37(6)27(28(39)25-34)14-15-30-36(5)19-18-31(35(3,4)29(36)17-20-38(30,37)7)43-32(40)16-13-26-11-9-8-10-12-26/h8-14,16,28-31H,15,17-25H2,1-7H3,(H,41,42)/b16-13+/t28-,29-,30+,31-,36-,37+,38+,39-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50102746
(CHEMBL3343062)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C39H54O4/c1-34(2)21-23-39(33(41)42)24-22-37(6)27(28(39)25-34)14-15-30-36(5)19-18-31(35(3,4)29(36)17-20-38(30,37)7)43-32(40)16-13-26-11-9-8-10-12-26/h8-14,16,28-31H,15,17-25H2,1-7H3,(H,41,42)/b16-13+/t28-,29-,30+,31-,36-,37+,38+,39-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50160399
(CHEMBL3786595)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC5(OCCO5)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]1(CO)CCC(C)(C)C=C21 |r,t:40| Show InChI InChI=1S/C32H52O3/c1-26(2)12-15-31(21-33)16-14-29(6)22(23(31)20-26)8-9-25-28(5)13-17-32(34-18-19-35-32)27(3,4)24(28)10-11-30(25,29)7/h20,22,24-25,33H,8-19,21H2,1-7H3/t22-,24+,25-,28+,29-,30-,31-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102747
(CHEMBL3343063)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C31H50O3/c1-26(2)15-17-31(25(32)33)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(34-8)27(3,4)22(28)11-14-30(23,29)7/h9,21-24H,10-19H2,1-8H3,(H,32,33)/t21-,22-,23+,24-,28-,29+,30+,31-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50218200
((3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(hydroxymet...)Show SMILES CC1(C)CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:12| Show InChI InChI=1S/C30H50O2/c1-25(2)14-16-30(19-31)17-15-28(6)20(21(30)18-25)8-9-23-27(5)12-11-24(32)26(3,4)22(27)10-13-29(23,28)7/h8,21-24,31-32H,9-19H2,1-7H3/t21-,22-,23+,24-,27-,28+,29+,30+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50158368
(CHEMBL3787288)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C)(C)C=C21)C(=O)OC |r,t:34| Show InChI InChI=1S/C31H48O3/c1-26(2)15-17-31(25(33)34-8)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(32)27(3,4)22(28)11-14-30(23,29)7/h19-20,22-23H,9-18H2,1-8H3/t20-,22+,23-,28+,29-,30-,31+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50102746
(CHEMBL3343062)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C39H54O4/c1-34(2)21-23-39(33(41)42)24-22-37(6)27(28(39)25-34)14-15-30-36(5)19-18-31(35(3,4)29(36)17-20-38(30,37)7)43-32(40)16-13-26-11-9-8-10-12-26/h8-14,16,28-31H,15,17-25H2,1-7H3,(H,41,42)/b16-13+/t28-,29-,30+,31-,36-,37+,38+,39-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of TC-PTP (unknown origin) using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50102746
(CHEMBL3343062)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C39H54O4/c1-34(2)21-23-39(33(41)42)24-22-37(6)27(28(39)25-34)14-15-30-36(5)19-18-31(35(3,4)29(36)17-20-38(30,37)7)43-32(40)16-13-26-11-9-8-10-12-26/h8-14,16,28-31H,15,17-25H2,1-7H3,(H,41,42)/b16-13+/t28-,29-,30+,31-,36-,37+,38+,39-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM54263
((4aS,6aR,6aR,6bR,8aR,12aR,14aS)-10-keto-2,2,6a,6b,...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@@]34C)C2=C1)C(O)=O |c:32| Show InChI InChI=1S/C30H46O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h18-19,21-22H,8-17H2,1-7H3,(H,32,33)/t19-,21+,22-,27+,28-,29-,30+/m1/s1 | PDB
MMDB
NCI pathway
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| n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50160399
(CHEMBL3786595)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC5(OCCO5)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]1(CO)CCC(C)(C)C=C21 |r,t:40| Show InChI InChI=1S/C32H52O3/c1-26(2)12-15-31(21-33)16-14-29(6)22(23(31)20-26)8-9-25-28(5)13-17-32(34-18-19-35-32)27(3,4)24(28)10-11-30(25,29)7/h20,22,24-25,33H,8-19,21H2,1-7H3/t22-,24+,25-,28+,29-,30-,31-/m1/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL
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PubMed
| n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human LMW-PTP isoform 1 expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102742
(CHEMBL3126477)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)c4ccccc4)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C37H52O4/c1-32(2)19-21-37(31(39)40)22-20-35(6)25(26(37)23-32)13-14-28-34(5)17-16-29(41-30(38)24-11-9-8-10-12-24)33(3,4)27(34)15-18-36(28,35)7/h8-13,26-29H,14-23H2,1-7H3,(H,39,40)/t26-,27-,28+,29-,34-,35+,36+,37-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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PubMed
| n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50102748
(CHEMBL3343064)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H52O3/c1-9-35-25-13-14-29(6)23(28(25,4)5)12-15-31(8)24(29)11-10-21-22-20-27(2,3)16-18-32(22,26(33)34)19-17-30(21,31)7/h10,22-25H,9,11-20H2,1-8H3,(H,33,34)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102744
(CHEMBL3343061)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)\C=C\C)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C34H52O4/c1-9-10-27(35)38-26-14-15-31(6)24(30(26,4)5)13-16-33(8)25(31)12-11-22-23-21-29(2,3)17-19-34(23,28(36)37)20-18-32(22,33)7/h9-11,23-26H,12-21H2,1-8H3,(H,36,37)/b10-9+/t23-,24-,25+,26-,31-,32+,33+,34-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
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PubMed
| n/a | n/a | 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102741
(3-O-Acetyloleanolic Acid | Acetyl Oleanolic Acid)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OC(C)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H50O4/c1-20(33)36-25-12-13-29(6)23(28(25,4)5)11-14-31(8)24(29)10-9-21-22-19-27(2,3)15-17-32(22,26(34)35)18-16-30(21,31)7/h9,22-25H,10-19H2,1-8H3,(H,34,35)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| Purchase
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PC sid
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| Article
PubMed
| n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
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KEGG
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| Article
PubMed
| n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50102748
(CHEMBL3343064)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H52O3/c1-9-35-25-13-14-29(6)23(28(25,4)5)12-15-31(8)24(29)11-10-21-22-20-27(2,3)16-18-32(22,26(33)34)19-17-30(21,31)7/h10,22-25H,9,11-20H2,1-8H3,(H,33,34)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of TC-PTP (unknown origin) using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50160399
(CHEMBL3786595)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC5(OCCO5)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]1(CO)CCC(C)(C)C=C21 |r,t:40| Show InChI InChI=1S/C32H52O3/c1-26(2)12-15-31(21-33)16-14-29(6)22(23(31)20-26)8-9-25-28(5)13-17-32(34-18-19-35-32)27(3,4)24(28)10-11-30(25,29)7/h20,22,24-25,33H,8-19,21H2,1-7H3/t22-,24+,25-,28+,29-,30-,31-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human LMW-PTP isoform 2 expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50158368
(CHEMBL3787288)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C)(C)C=C21)C(=O)OC |r,t:34| Show InChI InChI=1S/C31H48O3/c1-26(2)15-17-31(25(33)34-8)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(32)27(3,4)22(28)11-14-30(23,29)7/h19-20,22-23H,9-18H2,1-8H3/t20-,22+,23-,28+,29-,30-,31+/m1/s1 | PDB
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antibodypedia
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| Article
PubMed
| n/a | n/a | 3.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human LMW-PTP isoform 1 expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50102749
(CHEMBL3343065)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C33H54O3/c1-9-20-36-26-13-14-30(6)24(29(26,4)5)12-15-32(8)25(30)11-10-22-23-21-28(2,3)16-18-33(23,27(34)35)19-17-31(22,32)7/h10,23-26H,9,11-21H2,1-8H3,(H,34,35)/t23-,24-,25+,26-,30-,31+,32+,33-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50102748
(CHEMBL3343064)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](OCC)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C32H52O3/c1-9-35-25-13-14-29(6)23(28(25,4)5)12-15-31(8)24(29)11-10-21-22-20-27(2,3)16-18-32(22,26(33)34)19-17-30(21,31)7/h10,22-25H,9,11-20H2,1-8H3,(H,33,34)/t22-,23-,24+,25-,29-,30+,31+,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometry |
Eur J Med Chem 87: 316-27 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.036
BindingDB Entry DOI: 10.7270/Q2DB83NK |
More data for this
Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Homo sapiens (Human)) | BDBM50158368
(CHEMBL3787288)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C)(C)C=C21)C(=O)OC |r,t:34| Show InChI InChI=1S/C31H48O3/c1-26(2)15-17-31(25(33)34-8)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(32)27(3,4)22(28)11-14-30(23,29)7/h19-20,22-23H,9-18H2,1-8H3/t20-,22+,23-,28+,29-,30-,31+/m1/s1 | PDB
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antibodypedia
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CHEMBL
PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human LMW-PTP isoform 2 expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50158368
(CHEMBL3787288)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@]1(CCC(C)(C)C=C21)C(=O)OC |r,t:34| Show InChI InChI=1S/C31H48O3/c1-26(2)15-17-31(25(33)34-8)18-16-29(6)20(21(31)19-26)9-10-23-28(5)13-12-24(32)27(3,4)22(28)11-14-30(23,29)7/h19-20,22-23H,9-18H2,1-8H3/t20-,22+,23-,28+,29-,30-,31+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human TC-PTP expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50160399
(CHEMBL3786595)Show SMILES [H][C@]12CC[C@]3([H])[C@@]4(C)CCC5(OCCO5)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]1(CO)CCC(C)(C)C=C21 |r,t:40| Show InChI InChI=1S/C32H52O3/c1-26(2)12-15-31(21-33)16-14-29(6)22(23(31)20-26)8-9-25-28(5)13-17-32(34-18-19-35-32)27(3,4)24(28)10-11-30(25,29)7/h20,22,24-25,33H,8-19,21H2,1-7H3/t22-,24+,25-,28+,29-,30-,31-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Aut£noma del Estado de Morelos
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human TC-PTP expressed in Escherichia coli TB1 |
Bioorg Med Chem Lett 26: 2018-22 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.082
BindingDB Entry DOI: 10.7270/Q20Z7557 |
More data for this
Ligand-Target Pair | |
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