Compile Data Set for Download or QSAR

Found 41 hits with Last Name = 'flouquet' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50314074 (2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...) Show SMILES CP(C)(=O)c1ccc(Nc2nc(nc3n(CCc4cccc(O)c4)cnc23)C2CCCC2)cc1 Show InChI InChI=1S/C26H30N5O2P/c1-34(2,33)22-12-10-20(11-13-22)28-25-23-26(30-24(29-25)19-7-3-4-8-19)31(17-27-23)15-14-18-6-5-9-21(32)16-18/h5-6,9-13,16-17,19,32H,3-4,7-8,14-15H2,1-2H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
University of Lille Curated by ChEMBL					Assay Description Inhibition of Src				Eur J Med Chem 45: 5678-84 (2010) Article DOI: 10.1016/j.ejmech.2010.09.022 BindingDB Entry DOI: 10.7270/Q2B27Z30
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156464 (CHEMBL3793652) Show SMILES COc1ccc(cc1O)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C17H14N4O3/c1-20-16(23)11-5-3-4-6-12(11)21-15(18-19-17(20)21)10-7-8-14(24-2)13(22)9-10/h3-9,22H,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007118 (4-Amino-3-(5-chloro-thiophen-2-yl)-butyric acid | ...) Show SMILES NCC(CC(O)=O)c1ccc(Cl)s1 Show InChI InChI=1S/C8H10ClNO2S/c9-7-2-1-6(13-7)5(4-10)3-8(11)12/h1-2,5H,3-4,10H2,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007121 (4-Amino-3-(2-chloro-phenyl)-butyric acid | CHEMBL8...) Show SMILES NCC(CC(O)=O)c1ccccc1Cl Show InChI InChI=1S/C10H12ClNO2/c11-9-4-2-1-3-8(9)7(6-12)5-10(13)14/h1-4,7H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50368295 (CHEMBL301492) Show SMILES NC[C@H](CC(O)=O)c1ccc(F)cc1 Show InChI InChI=1S/C10H12FNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007107 (4-Amino-3-(5-methyl-thiophen-2-yl)-butyric acid | ...) Show SMILES Cc1ccc(s1)C(CN)CC(O)=O Show InChI InChI=1S/C9H13NO2S/c1-6-2-3-8(13-6)7(5-10)4-9(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007108 (4-Amino-3-(5-bromo-thiophen-2-yl)-butyric acid | C...) Show SMILES NCC(CC(O)=O)c1ccc(Br)s1 Show InChI InChI=1S/C8H10BrNO2S/c9-7-2-1-6(13-7)5(4-10)3-8(11)12/h1-2,5H,3-4,10H2,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156382 (CHEMBL3794202) Show SMILES COc1ccc(cc1O)-c1nnc2[nH]c(=O)c3ccccc3n12 Show InChI InChI=1S/C16H12N4O3/c1-23-13-7-6-9(8-12(13)21)14-18-19-16-17-15(22)10-4-2-3-5-11(10)20(14)16/h2-8,21H,1H3,(H,17,19,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021755 (4-Amino-3-(5-methoxy-benzofuran-2-yl)-butyric acid...) Show SMILES COc1ccc2oc(cc2c1)C(CN)CC(O)=O Show InChI InChI=1S/C13H15NO4/c1-17-10-2-3-11-8(4-10)5-12(18-11)9(7-14)6-13(15)16/h2-5,9H,6-7,14H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007117 (4-Amino-3-thiophen-2-yl-butyric acid | CHEMBL31547...) Show SMILES NCC(CC(O)=O)c1cccs1 Show InChI InChI=1S/C8H11NO2S/c9-5-6(4-8(10)11)7-2-1-3-12-7/h1-3,6H,4-5,9H2,(H,10,11)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156466 (CHEMBL3792479) Show SMILES COc1ccc(cc1OC)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C18H16N4O3/c1-21-17(23)12-6-4-5-7-13(12)22-16(19-20-18(21)22)11-8-9-14(24-2)15(10-11)25-3/h4-10H,1-3H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156467 (CHEMBL3794178) Show SMILES COc1ccc(cc1)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C17H14N4O2/c1-20-16(22)13-5-3-4-6-14(13)21-15(18-19-17(20)21)11-7-9-12(23-2)10-8-11/h3-10H,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156381 (CHEMBL3794460) Show SMILES COc1cc(ccc1O)-c1nnc2[nH]c(=O)c3ccccc3n12 Show InChI InChI=1S/C16H12N4O3/c1-23-13-8-9(6-7-12(13)21)14-18-19-16-17-15(22)10-4-2-3-5-11(10)20(14)16/h2-8,21H,1H3,(H,17,19,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156465 (CHEMBL3793967) Show SMILES COc1cc(cc(OC)c1OC)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C19H18N4O4/c1-22-18(24)12-7-5-6-8-13(12)23-17(20-21-19(22)23)11-9-14(25-2)16(27-4)15(10-11)26-3/h5-10H,1-4H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156463 (CHEMBL3793124) Show SMILES COc1cc(ccc1O)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C17H14N4O3/c1-20-16(23)11-5-3-4-6-12(11)21-15(18-19-17(20)21)10-7-8-13(22)14(9-10)24-2/h3-9,22H,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156462 (CHEMBL3793323) Show SMILES Cn1c2nnc(-c3ccc(O)c(O)c3)n2c2ccccc2c1=O Show InChI InChI=1S/C16H12N4O3/c1-19-15(23)10-4-2-3-5-11(10)20-14(17-18-16(19)20)9-6-7-12(21)13(22)8-9/h2-8,21-22H,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156447 (CHEMBL3792513) Show SMILES COc1ccc(cc1N)-c1nnc2n(C)c(=O)c3ccccc3n12 Show InChI InChI=1S/C17H15N5O2/c1-21-16(23)11-5-3-4-6-13(11)22-15(19-20-17(21)22)10-7-8-14(24-2)12(18)9-10/h3-9H,18H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156445 (CHEMBL3793547) Show SMILES COc1ccc(cc1)-c1nnc2[nH]c(=O)c3ccccc3n12 Show InChI InChI=1S/C16H12N4O2/c1-22-11-8-6-10(7-9-11)14-18-19-16-17-15(21)12-4-2-3-5-13(12)20(14)16/h2-9H,1H3,(H,17,19,21)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156384 (CHEMBL3793564) Show SMILES COc1cc(cc(OC)c1OC)-c1nnc2[nH]c(=O)c3ccccc3n12 Show InChI InChI=1S/C18H16N4O4/c1-24-13-8-10(9-14(25-2)15(13)26-3)16-20-21-18-19-17(23)11-6-4-5-7-12(11)22(16)18/h4-9H,1-3H3,(H,19,21,23)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50156444 (CHEMBL3792547) Show SMILES COc1ccc(cc1OC)-c1nnc2[nH]c(=O)c3ccccc3n12 Show InChI InChI=1S/C17H14N4O3/c1-23-13-8-7-10(9-14(13)24-2)15-19-20-17-18-16(22)11-5-3-4-6-12(11)21(15)17/h3-9H,1-2H3,(H,18,20,22)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry				Eur J Med Chem 115: 393-405 (2016) Article DOI: 10.1016/j.ejmech.2016.03.056 BindingDB Entry DOI: 10.7270/Q2RN39RQ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021756 (4-Amino-3-benzofuran-2-yl-butyric acid | CHEMBL349...) Show SMILES NCC(CC(O)=O)c1cc2ccccc2o1 Show InChI InChI=1S/C12H13NO3/c13-7-9(6-12(14)15)11-5-8-3-1-2-4-10(8)16-11/h1-5,9H,6-7,13H2,(H,14,15)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007109 (4-Amino-3-(3-chloro-phenyl)-butyric acid | CHEMBL3...) Show SMILES NCC(CC(O)=O)c1cccc(Cl)c1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-2-7(4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007113 (4-Amino-3-thiophen-3-yl-butyric acid | CHEMBL87856) Show SMILES NCC(CC(O)=O)c1ccsc1 Show InChI InChI=1S/C8H11NO2S/c9-4-7(3-8(10)11)6-1-2-12-5-6/h1-2,5,7H,3-4,9H2,(H,10,11)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007110 (4-Amino-3-(4-bromo-thiophen-2-yl)-butyric acid | C...) Show SMILES NCC(CC(O)=O)c1cc(Br)cs1 Show InChI InChI=1S/C8H10BrNO2S/c9-6-2-7(13-4-6)5(3-10)1-8(11)12/h2,4-5H,1,3,10H2,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007111 (4-Amino-3-(4-chloro-thiophen-2-yl)-butyric acid | ...) Show SMILES NCC(CC(O)=O)c1cc(Cl)cs1 Show InChI InChI=1S/C8H10ClNO2S/c9-6-2-7(13-4-6)5(3-10)1-8(11)12/h2,4-5H,1,3,10H2,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007120 (4-Amino-3-(4-hydroxy-phenyl)-butyric acid | CHEMBL...) Show SMILES NCC(CC(O)=O)c1ccc(O)cc1 Show InChI InChI=1S/C10H13NO3/c11-6-8(5-10(13)14)7-1-3-9(12)4-2-7/h1-4,8,12H,5-6,11H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007119 (4-Amino-3-phenyl-butyric acid | CHEMBL53073) Show SMILES NC[C@H](CC(O)=O)c1ccccc1 Show InChI InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007114 (4-Amino-3-furan-2-yl-butyric acid | CHEMBL85880) Show SMILES NCC(CC(O)=O)c1ccco1 Show InChI InChI=1S/C8H11NO3/c9-5-6(4-8(10)11)7-2-1-3-12-7/h1-3,6H,4-5,9H2,(H,10,11)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007112 (4-Amino-3-(5-methyl-furan-2-yl)-butyric acid | CHE...) Show SMILES Cc1ccc(o1)C(CN)CC(O)=O Show InChI InChI=1S/C9H13NO3/c1-6-2-3-8(13-6)7(5-10)4-9(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021761 (4-Amino-3-[4-(4-fluoro-benzyloxy)-phenyl]-butyric ...) Show SMILES NCC(CC(O)=O)c1ccc(OCc2ccc(F)cc2)cc1 Show InChI InChI=1S/C17H18FNO3/c18-15-5-1-12(2-6-15)11-22-16-7-3-13(4-8-16)14(10-19)9-17(20)21/h1-8,14H,9-11,19H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021759 (4-Amino-3-(5-methoxy-2,3-dihydro-benzofuran-2-yl)-...) Show SMILES COc1ccc2OC(Cc2c1)C(CN)CC(O)=O Show InChI InChI=1S/C13H17NO4/c1-17-10-2-3-11-8(4-10)5-12(18-11)9(7-14)6-13(15)16/h2-4,9,12H,5-7,14H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021763 (4-Amino-3-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-...) Show SMILES Cn1c2ccc(cc2oc1=O)C(CN)CC(O)=O Show InChI InChI=1S/C12H14N2O4/c1-14-9-3-2-7(4-10(9)18-12(14)17)8(6-13)5-11(15)16/h2-4,8H,5-6,13H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021758 (4-Amino-3-(2,3-dihydro-benzofuran-2-yl)-butyric ac...) Show SMILES NCC(CC(O)=O)C1Cc2ccccc2O1 Show InChI InChI=1S/C12H15NO3/c13-7-9(6-12(14)15)11-5-8-3-1-2-4-10(8)16-11/h1-4,9,11H,5-7,13H2,(H,14,15)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007120 (4-Amino-3-(4-hydroxy-phenyl)-butyric acid | CHEMBL...) Show SMILES NCC(CC(O)=O)c1ccc(O)cc1 Show InChI InChI=1S/C10H13NO3/c11-6-8(5-10(13)14)7-1-3-9(12)4-2-7/h1-4,8,12H,5-6,11H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50021757 (4-Amino-3-(4-benzyloxy-phenyl)-butyric acid; hydro...) Show SMILES NCC(CC(O)=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H19NO3/c18-11-15(10-17(19)20)14-6-8-16(9-7-14)21-12-13-4-2-1-3-5-13/h1-9,15H,10-12,18H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM50007116 (4-Amino-3-(3-methyl-thiophen-2-yl)-butyric acid | ...) Show SMILES Cc1ccsc1C(CN)CC(O)=O Show InChI InChI=1S/C9H13NO2S/c1-6-2-3-13-9(6)7(5-10)4-8(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair