Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'francotte' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032241 (CHEMBL2441067) Show SMILES Fc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C10H11FN2O2S/c11-7-1-4-9-10(5-7)16(14,15)12-6-13(9)8-2-3-8/h1,4-5,8,12H,2-3,6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Binding affinity to GluA2-LBD-L483Y-N754S complex (unknown origin) by isothermal titration calorimetry				J Med Chem 57: 9539-53 (2014) Article DOI: 10.1021/jm501268r BindingDB Entry DOI: 10.7270/Q2Q241VZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Rattus norvegicus)	BDBM50493771 (CHEMBL2441069) Show SMILES Brc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C10H11BrN2O2S/c11-7-1-4-9-10(5-7)16(14,15)12-6-13(9)8-2-3-8/h1,4-5,8,12H,2-3,6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 receptor in rat embryonic cortex neuron assessed as increase of AMPA-induced membrane depolarization by fluor...				J Med Chem 56: 8736-45 (2013) Article DOI: 10.1021/jm4012092 BindingDB Entry DOI: 10.7270/Q2C250D0
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032245 (CHEMBL99732) Show SMILES CCN1CNS(=O)(=O)c2cnccc12 Show InChI InChI=1S/C8H11N3O2S/c1-2-11-6-10-14(12,13)8-5-9-4-3-7(8)11/h3-5,10H,2,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.20E+6	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Binding affinity to GluA2-LBD-L483Y-N754S complex (unknown origin) by isothermal titration calorimetry				J Med Chem 57: 9539-53 (2014) Article DOI: 10.1021/jm501268r BindingDB Entry DOI: 10.7270/Q2Q241VZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032248 (CHEMBL103741) Show SMILES CCN1CNS(=O)(=O)c2ncccc12 Show InChI InChI=1S/C8H11N3O2S/c1-2-11-6-10-14(12,13)8-7(11)4-3-5-9-8/h3-5,10H,2,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Binding affinity to GluA2-LBD-L483Y-N754S complex (unknown origin) by isothermal titration calorimetry				J Med Chem 57: 9539-53 (2014) Article DOI: 10.1021/jm501268r BindingDB Entry DOI: 10.7270/Q2Q241VZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251223 (CHEMBL4091590) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccccc3C)ccc12 Show InChI InChI=1S/C15H16N2O3S/c1-11-5-3-4-6-14(11)20-12-7-8-13-15(9-12)21(18,19)16-10-17(13)2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251225 (CHEMBL4073898) Show SMILES Cc1ccccc1Oc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C17H18N2O3S/c1-12-4-2-3-5-16(12)22-14-8-9-15-17(10-14)23(20,21)18-11-19(15)13-6-7-13/h2-5,8-10,13,18H,6-7,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251226 (CHEMBL4071167) Show SMILES COc1ccccc1Oc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C17H18N2O4S/c1-22-15-4-2-3-5-16(15)23-13-8-9-14-17(10-13)24(20,21)18-11-19(14)12-6-7-12/h2-5,8-10,12,18H,6-7,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251227 (CHEMBL4084231) Show SMILES Cc1ccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)cc1 Show InChI InChI=1S/C17H18N2O3S/c1-12-2-6-14(7-3-12)22-15-8-9-16-17(10-15)23(20,21)18-11-19(16)13-4-5-13/h2-3,6-10,13,18H,4-5,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.19E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251228 (CHEMBL4100668) Show SMILES O=S1(=O)NCN(C2CC2)c2ccc(Oc3ccccc3)cc12 Show InChI InChI=1S/C16H16N2O3S/c19-22(20)16-10-14(21-13-4-2-1-3-5-13)8-9-15(16)18(11-17-22)12-6-7-12/h1-5,8-10,12,17H,6-7,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251230 (CHEMBL4062069) Show SMILES COc1ccccc1Oc1ccc2N(C)CNS(=O)(=O)c2c1 Show InChI InChI=1S/C15H16N2O4S/c1-17-10-16-22(18,19)15-9-11(7-8-12(15)17)21-14-6-4-3-5-13(14)20-2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251231 (CHEMBL4083809) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccc(C)cc3)ccc12 Show InChI InChI=1S/C15H16N2O3S/c1-11-3-5-12(6-4-11)20-13-7-8-14-15(9-13)21(18,19)16-10-17(14)2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	950	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251224 (CHEMBL4073431) Show SMILES CC1N(C)c2ccc(Cl)cc2S(=O)(=O)N1C Show InChI InChI=1S/C10H13ClN2O2S/c1-7-12(2)9-5-4-8(11)6-10(9)16(14,15)13(7)3/h4-7H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251234 (CHEMBL4081714) Show SMILES COc1ccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)cc1 Show InChI InChI=1S/C17H18N2O4S/c1-22-13-4-6-14(7-5-13)23-15-8-9-16-17(10-15)24(20,21)18-11-19(16)12-2-3-12/h4-10,12,18H,2-3,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251233 (CHEMBL4092527) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccccc3)ccc12 Show InChI InChI=1S/C14H14N2O3S/c1-16-10-15-20(17,18)14-9-12(7-8-13(14)16)19-11-5-3-2-4-6-11/h2-9,15H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.62E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032241 (CHEMBL2441067) Show SMILES Fc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C10H11FN2O2S/c11-7-1-4-9-10(5-7)16(14,15)12-6-13(9)8-2-3-8/h1,4-5,8,12H,2-3,6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251239 (CHEMBL581906) Show SMILES FCCN1CNS(=O)(=O)c2cc(Cl)ccc12 Show InChI InChI=1S/C9H10ClFN2O2S/c10-7-1-2-8-9(5-7)16(14,15)12-6-13(8)4-3-11/h1-2,5,12H,3-4,6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251229 (CHEMBL4089172) Show SMILES COc1ccc(Oc2ccc3N(C)CNS(=O)(=O)c3c2)cc1 Show InChI InChI=1S/C15H16N2O4S/c1-17-10-16-22(18,19)15-9-13(7-8-14(15)17)21-12-5-3-11(20-2)4-6-12/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251232 (CHEMBL4070694) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3cccc(C)c3)ccc12 Show InChI InChI=1S/C15H16N2O3S/c1-11-4-3-5-12(8-11)20-13-6-7-14-15(9-13)21(18,19)16-10-17(14)2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251235 (CHEMBL4066717) Show SMILES O=S1(=O)NCN(C2CC2)c2ccc(Oc3cccc(c3)C#N)cc12 Show InChI InChI=1S/C17H15N3O3S/c18-10-12-2-1-3-14(8-12)23-15-6-7-16-17(9-15)24(21,22)19-11-20(16)13-4-5-13/h1-3,6-9,13,19H,4-5,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	454	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251237 (CHEMBL4062524) Show SMILES Cc1cccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)c1 Show InChI InChI=1S/C17H18N2O3S/c1-12-3-2-4-14(9-12)22-15-7-8-16-17(10-15)23(20,21)18-11-19(16)13-5-6-13/h2-4,7-10,13,18H,5-6,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251238 (CHEMBL4060993) Show SMILES COc1cccc(Oc2ccc3N(C)CNS(=O)(=O)c3c2)c1 Show InChI InChI=1S/C15H16N2O4S/c1-17-10-16-22(18,19)15-9-13(6-7-14(15)17)21-12-5-3-4-11(8-12)20-2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	371	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032248 (CHEMBL103741) Show SMILES CCN1CNS(=O)(=O)c2ncccc12 Show InChI InChI=1S/C8H11N3O2S/c1-2-11-6-10-14(12,13)8-7(11)4-3-5-9-8/h3-5,10H,2,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	5.06E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251236 (CHEMBL4091984) Show SMILES COc1cccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)c1 Show InChI InChI=1S/C17H18N2O4S/c1-22-13-3-2-4-14(9-13)23-15-7-8-16-17(10-15)24(20,21)18-11-19(16)12-5-6-12/h2-4,7-10,12,18H,5-6,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457614 (CHEMBL4202524) Show SMILES CN1CNS(=O)(=O)c2ccc(CCc3ccc4c(c3)N(C)CNS4(=O)=O)cc12 Show InChI InChI=1S/C18H22N4O4S2/c1-21-11-19-27(23,24)17-7-5-13(9-15(17)21)3-4-14-6-8-18-16(10-14)22(2)12-20-28(18,25)26/h5-10,19-20H,3-4,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457615 (CHEMBL226584) Show SMILES CN1CNS(=O)(=O)c2ccccc12 Show InChI InChI=1S/C8H10N2O2S/c1-10-6-9-13(11,12)8-5-3-2-4-7(8)10/h2-5,9H,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457616 (CHEMBL4218628) Show SMILES O=S1(=O)NCN(C2CC2)c2cc(CCc3ccc4c(c3)N(CNS4(=O)=O)C3CC3)ccc12 Show InChI InChI=1S/C22H26N4O4S2/c27-31(28)21-9-3-15(11-19(21)25(13-23-31)17-5-6-17)1-2-16-4-10-22-20(12-16)26(18-7-8-18)14-24-32(22,29)30/h3-4,9-12,17-18,23-24H,1-2,5-8,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457615 (CHEMBL226584) Show SMILES CN1CNS(=O)(=O)c2ccccc12 Show InChI InChI=1S/C8H10N2O2S/c1-10-6-9-13(11,12)8-5-3-2-4-7(8)10/h2-5,9H,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.76E+5	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457617 (CHEMBL4206371) Show SMILES Cc1ccc2c(c1)N(CNS2(=O)=O)C1CC1 Show InChI InChI=1S/C11H14N2O2S/c1-8-2-5-11-10(6-8)13(9-3-4-9)7-12-16(11,14)15/h2,5-6,9,12H,3-4,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457614 (CHEMBL4202524) Show SMILES CN1CNS(=O)(=O)c2ccc(CCc3ccc4c(c3)N(C)CNS4(=O)=O)cc12 Show InChI InChI=1S/C18H22N4O4S2/c1-21-11-19-27(23,24)17-7-5-13(9-15(17)21)3-4-14-6-8-18-16(10-14)22(2)12-20-28(18,25)26/h5-10,19-20H,3-4,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	14.5	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457617 (CHEMBL4206371) Show SMILES Cc1ccc2c(c1)N(CNS2(=O)=O)C1CC1 Show InChI InChI=1S/C11H14N2O2S/c1-8-2-5-11-10(6-8)13(9-3-4-9)7-12-16(11,14)15/h2,5-6,9,12H,3-4,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457618 (CHEMBL4206883) Show SMILES CN1CNS(=O)(=O)c2ccc(C)cc12 Show InChI InChI=1S/C9H12N2O2S/c1-7-3-4-9-8(5-7)11(2)6-10-14(9,12)13/h3-5,10H,6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.07E+5	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457619 (CHEMBL2441066) Show SMILES O=S1(=O)NCN(C2CC2)c2ccccc12 Show InChI InChI=1S/C10H12N2O2S/c13-15(14)10-4-2-1-3-9(10)12(7-11-15)8-5-6-8/h1-4,8,11H,5-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.06E+3	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457619 (CHEMBL2441066) Show SMILES O=S1(=O)NCN(C2CC2)c2ccccc12 Show InChI InChI=1S/C10H12N2O2S/c13-15(14)10-4-2-1-3-9(10)12(7-11-15)8-5-6-8/h1-4,8,11H,5-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.12E+3	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457616 (CHEMBL4218628) Show SMILES O=S1(=O)NCN(C2CC2)c2cc(CCc3ccc4c(c3)N(CNS4(=O)=O)C3CC3)ccc12 Show InChI InChI=1S/C22H26N4O4S2/c27-31(28)21-9-3-15(11-19(21)25(13-23-31)17-5-6-17)1-2-16-4-10-22-20(12-16)26(18-7-8-18)14-24-32(22,29)30/h3-4,9-12,17-18,23-24H,1-2,5-8,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.26	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50457618 (CHEMBL4206883) Show SMILES CN1CNS(=O)(=O)c2ccc(C)cc12 Show InChI InChI=1S/C9H12N2O2S/c1-7-3-4-9-8(5-7)11(2)6-10-14(9,12)13/h3-5,10H,6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.03E+5	n/a	n/a	n/a	n/a
University of Liege Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2Q flop isoform (unknown origin) expressed in HEK293 cells assessed as increase in L-glutamate induced calcium ...				J Med Chem 61: 5279-5291 (2018) Article DOI: 10.1021/acs.jmedchem.8b00250 BindingDB Entry DOI: 10.7270/Q20C4ZCF
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251231 (CHEMBL4083809) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccc(C)cc3)ccc12 Show InChI InChI=1S/C15H16N2O3S/c1-11-3-5-12(6-4-11)20-13-7-8-14-15(9-13)21(18,19)16-10-17(14)2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	955	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251235 (CHEMBL4066717) Show SMILES O=S1(=O)NCN(C2CC2)c2ccc(Oc3cccc(c3)C#N)cc12 Show InChI InChI=1S/C17H15N3O3S/c18-10-12-2-1-3-14(8-12)23-15-6-7-16-17(9-15)24(21,22)19-11-20(16)13-4-5-13/h1-3,6-9,13,19H,4-5,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251234 (CHEMBL4081714) Show SMILES COc1ccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)cc1 Show InChI InChI=1S/C17H18N2O4S/c1-22-13-4-6-14(7-5-13)23-15-8-9-16-17(10-15)24(20,21)18-11-19(16)12-2-3-12/h4-10,12,18H,2-3,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251237 (CHEMBL4062524) Show SMILES Cc1cccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)c1 Show InChI InChI=1S/C17H18N2O3S/c1-12-3-2-4-14(9-12)22-15-7-8-16-17(10-15)23(20,21)18-11-19(16)13-5-6-13/h2-4,7-10,13,18H,5-6,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251224 (CHEMBL4073431) Show SMILES CC1N(C)c2ccc(Cl)cc2S(=O)(=O)N1C Show InChI InChI=1S/C10H13ClN2O2S/c1-7-12(2)9-5-4-8(11)6-10(9)16(14,15)13(7)3/h4-7H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251223 (CHEMBL4091590) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccccc3C)ccc12 Show InChI InChI=1S/C15H16N2O3S/c1-11-5-3-4-6-14(11)20-12-7-8-13-15(9-12)21(18,19)16-10-17(13)2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251236 (CHEMBL4091984) Show SMILES COc1cccc(Oc2ccc3N(CNS(=O)(=O)c3c2)C2CC2)c1 Show InChI InChI=1S/C17H18N2O4S/c1-22-13-3-2-4-14(9-13)23-15-7-8-16-17(10-15)24(20,21)18-11-19(16)12-5-6-12/h2-4,7-10,12,18H,5-6,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251226 (CHEMBL4071167) Show SMILES COc1ccccc1Oc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C17H18N2O4S/c1-22-15-4-2-3-5-16(15)23-13-8-9-14-17(10-13)24(20,21)18-11-19(14)12-6-7-12/h2-5,8-10,12,18H,6-7,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032241 (CHEMBL2441067) Show SMILES Fc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C10H11FN2O2S/c11-7-1-4-9-10(5-7)16(14,15)12-6-13(9)8-2-3-8/h1,4-5,8,12H,2-3,6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251238 (CHEMBL4060993) Show SMILES COc1cccc(Oc2ccc3N(C)CNS(=O)(=O)c3c2)c1 Show InChI InChI=1S/C15H16N2O4S/c1-17-10-16-22(18,19)15-9-13(6-7-14(15)17)21-12-5-3-4-11(8-12)20-2/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50032248 (CHEMBL103741) Show SMILES CCN1CNS(=O)(=O)c2ncccc12 Show InChI InChI=1S/C8H11N3O2S/c1-2-11-6-10-14(12,13)8-7(11)4-3-5-9-8/h3-5,10H,2,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	5.06E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251229 (CHEMBL4089172) Show SMILES COc1ccc(Oc2ccc3N(C)CNS(=O)(=O)c3c2)cc1 Show InChI InChI=1S/C15H16N2O4S/c1-17-10-16-22(18,19)15-9-13(7-8-14(15)17)21-12-5-3-11(20-2)4-6-12/h3-9,16H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251228 (CHEMBL4100668) Show SMILES O=S1(=O)NCN(C2CC2)c2ccc(Oc3ccccc3)cc12 Show InChI InChI=1S/C16H16N2O3S/c19-22(20)16-10-14(21-13-4-2-1-3-5-13)8-9-15(16)18(11-17-22)12-6-7-12/h1-5,8-10,12,17H,6-7,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	713	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251233 (CHEMBL4092527) Show SMILES CN1CNS(=O)(=O)c2cc(Oc3ccccc3)ccc12 Show InChI InChI=1S/C14H14N2O3S/c1-16-10-15-20(17,18)14-9-12(7-8-13(14)16)19-11-5-3-2-4-6-11/h2-9,15H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.62E+3	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50251225 (CHEMBL4073898) Show SMILES Cc1ccccc1Oc1ccc2N(CNS(=O)(=O)c2c1)C1CC1 Show InChI InChI=1S/C17H18N2O3S/c1-12-4-2-3-5-16(12)22-14-8-9-15-17(10-14)23(20,21)18-11-19(15)13-6-7-13/h2-5,8-10,13,18H,6-7,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
Laboratory of Medicinal Chemistry, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège , Quartier Hôpital B36 Av. Hippocrate 15 B-4000 Liège, Belgium. Curated by ChEMBL					Assay Description Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...				J Med Chem 61: 251-264 (2018) Article DOI: 10.1021/acs.jmedchem.7b01323 BindingDB Entry DOI: 10.7270/Q2Z89FV2
					More data for this Ligand-Target Pair

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