BindingDB PrimarySearch

Found 26 hits with Last Name = 'fremming' and Initial = 't'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.96E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	7.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM56470 (2-(2-Imino-3-methyl-2,3-dihydro-benzoimidazol-1-yl...) Show SMILES Cn1c2ccccc2n(CC(=O)c2cccs2)c1=N Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as activation of K+ currents				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210318 (6-chloro-4-hydroxy-2-oxo-N-1,3-thiazol-2-yl-2H-chr...) Show SMILES Oc1c(C(=O)Nc2nccs2)c(=O)oc2ccc(Cl)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210319 (4-amino-6-methoxy-2-(trifluoromethyl)quinoline-3-c...) Show SMILES COc1ccc2nc(c(C#N)c(N)c2c1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210320 (CHEMBL226918 \| [(2Z)-4-(4-fluorophenyl)-2-[(4-fluo...) Show SMILES OCCn1c(cs\c1=N/c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as activation of K+ currents				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210321 (5-methoxy-2-piperidin-1-yl-1H-benzimidazole \| CHEM...) Show SMILES COc1ccc2nc([nH]c2c1)N1CCCCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50130735 ((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda6-benzo[1...) Show SMILES CC(C)NC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:4\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210322 (CHEMBL374743 \| N-[1-(2-pyrrolidin-1-ylethyl)-1H-be...) Show SMILES CC(=O)Nc1nc2ccccc2n1CCN1CCCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210324 (6-phenylpteridin-4(3H)-one \| CHEMBL228035) Show SMILES O=c1[nH]cnc2ncc(nc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210323 (2-{[(4-chlorophenyl)sulfonyl]amino}benzamide \| CHE...) Show SMILES NC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50210325 (3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-carboni...) Show SMILES O=c1[nH]nc(-c2ccccc2)c(-c2ccccc2)c1C#N Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190502 (6-bromo-3-(1-methylcyclopropyl)amino-4H-thieno[3,2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190496 (6-chloro-3-(1-phenylcyclopropyl)amino-4H-thieno[3,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 \| NSC_3019 \| diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 \|t:1\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190501 (6-chloro-3-{[1-(trifluoromethyl)cyclopropyl]-amino...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
Novo Nordisk Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarization				J Med Chem 50: 2117-26 (2007) Article DOI: 10.1021/jm061440p BindingDB Entry DOI: 10.7270/Q2PK0FTT
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair