Compile Data Set for Download or QSAR

Found 54 hits with Last Name = 'fuchibe' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285498 (4-[4-Cyano-2-({[(1R,2R)-6′-(methylcarbamoyl)...) Show SMILES CNC(=O)c1ccc2CC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C25H25N3O4/c1-27-23(31)18-8-7-16-9-10-25(19(16)12-18)13-20(25)24(32)28-21-11-15(14-26)5-6-17(21)3-2-4-22(29)30/h5-8,11-12,20H,2-4,9-10,13H2,1H3,(H,27,31)(H,28,32)(H,29,30)/t20-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285464 (4-{4-Cyano-2-[({2′R, 4S)-6-[(1-methyl 1H-pyr...) Show SMILES Cn1cc(NC(=O)c2ccc3OCC[C@]4(C[C@H]4C(=O)Nc4cc(ccc4CCCC(O)=O)C#N)c3c2)cn1 |r| Show InChI InChI=1S/C28H27N5O5/c1-33-16-20(15-30-33)31-26(36)19-7-8-24-21(12-19)28(9-10-38-24)13-22(28)27(37)32-23-11-17(14-29)5-6-18(23)3-2-4-25(34)35/h5-8,11-12,15-16,22H,2-4,9-10,13H2,1H3,(H,31,36)(H,32,37)(H,34,35)/t22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285502 (US10077247, Example 20-2) Show SMILES COCCNC(=O)c1cc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)cc1F |r| Show InChI InChI=1S/C27H28FN3O6/c1-36-10-8-30-25(34)18-12-19-23(13-21(18)28)37-9-7-27(19)14-20(27)26(35)31-22-11-16(15-29)5-6-17(22)3-2-4-24(32)33/h5-6,11-13,20H,2-4,7-10,14H2,1H3,(H,30,34)(H,31,35)(H,32,33)/t20-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285487 (4-[4-Cyano-2-({[(2′R,4S)-6-(1H-pyrazol-1-yl)...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-n1cccn1)C#N |r| Show InChI InChI=1S/C26H24N4O4/c27-16-17-5-6-18(3-1-4-24(31)32)22(13-17)29-25(33)21-15-26(21)9-12-34-23-8-7-19(14-20(23)26)30-11-2-10-28-30/h2,5-8,10-11,13-14,21H,1,3-4,9,12,15H2,(H,29,33)(H,31,32)/t21-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285480 (4-[4-Cyano-2-({[(2′R,4S)-6-(propylcarbamoyl)...) Show SMILES CCCNC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C27H29N3O5/c1-2-11-29-25(33)19-8-9-23-20(14-19)27(10-12-35-23)15-21(27)26(34)30-22-13-17(16-28)6-7-18(22)4-3-5-24(31)32/h6-9,13-14,21H,2-5,10-12,15H2,1H3,(H,29,33)(H,30,34)(H,31,32)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285036 (US10077247, Example 1) Show SMILES CNC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C25H25N3O5/c1-27-23(31)17-7-8-21-18(12-17)25(9-10-33-21)13-19(25)24(32)28-20-11-15(14-26)5-6-16(20)3-2-4-22(29)30/h5-8,11-12,19H,2-4,9-10,13H2,1H3,(H,27,31)(H,28,32)(H,29,30)/t19-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285470 (4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridazinylcar...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1cccnn1)C#N |r| Show InChI InChI=1S/C28H25N5O5/c29-16-17-6-7-18(3-1-5-25(34)35)22(13-17)31-27(37)21-15-28(21)10-12-38-23-9-8-19(14-20(23)28)26(36)32-24-4-2-11-30-33-24/h2,4,6-9,11,13-14,21H,1,3,5,10,12,15H2,(H,31,37)(H,34,35)(H,32,33,36)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285483 (4-[4-Cyano-2-({[(2′R,4S)-6-(5-methyl-1,3,4-o...) Show SMILES Cc1nnc(o1)-c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C26H24N4O5/c1-15-29-30-25(35-15)18-7-8-22-19(12-18)26(9-10-34-22)13-20(26)24(33)28-21-11-16(14-27)5-6-17(21)3-2-4-23(31)32/h5-8,11-12,20H,2-4,9-10,13H2,1H3,(H,28,33)(H,31,32)/t20-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285500 (4-{4-Cyano-2-[({(1R,2R)-6′-[(1-methyl-1H-pyr...) Show SMILES Cn1cc(NC(=O)c2ccc3CC[C@]4(C[C@H]4C(=O)Nc4cc(ccc4CCCC(O)=O)C#N)c3c2)cn1 |r| Show InChI InChI=1S/C28H27N5O4/c1-33-16-21(15-30-33)31-26(36)20-8-7-18-9-10-28(22(18)12-20)13-23(28)27(37)32-24-11-17(14-29)5-6-19(24)3-2-4-25(34)35/h5-8,11-12,15-16,23H,2-4,9-10,13H2,1H3,(H,31,36)(H,32,37)(H,34,35)/t23-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285484 (US10077247, Example 5) Show SMILES Cc1noc(n1)-c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C26H24N4O5/c1-15-28-25(35-30-15)18-7-8-22-19(12-18)26(9-10-34-22)13-20(26)24(33)29-21-11-16(14-27)5-6-17(21)3-2-4-23(31)32/h5-8,11-12,20H,2-4,9-10,13H2,1H3,(H,29,33)(H,31,32)/t20-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285499 (4-{4-Cyano-2-[({(1R,2R)-6′-[(2-methoxyethyl)...) Show SMILES COCCNC(=O)c1ccc2CC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C27H29N3O5/c1-35-12-11-29-25(33)20-8-7-18-9-10-27(21(18)14-20)15-22(27)26(34)30-23-13-17(16-28)5-6-19(23)3-2-4-24(31)32/h5-8,13-14,22H,2-4,9-12,15H2,1H3,(H,29,33)(H,30,34)(H,31,32)/t22-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285482 (4-[4-Cyano-2-({[(2′R,4S)-6-(ethylcarbamoyl)-...) Show SMILES CCNC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C26H27N3O5/c1-2-28-24(32)18-8-9-22-19(13-18)26(10-11-34-22)14-20(26)25(33)29-21-12-16(15-27)6-7-17(21)4-3-5-23(30)31/h6-9,12-13,20H,2-5,10-11,14H2,1H3,(H,28,32)(H,29,33)(H,30,31)/t20-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285463 (US10077247, Example 2-4) Show SMILES COC[C@H](C)NC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C28H31N3O6/c1-17(16-36-2)30-26(34)20-8-9-24-21(13-20)28(10-11-37-24)14-22(28)27(35)31-23-12-18(15-29)6-7-19(23)4-3-5-25(32)33/h6-9,12-13,17,22H,3-5,10-11,14,16H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)/t17-,22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285476 (US10077247, Example 2-39) Show SMILES CC(C)(C)n1cc(NC(=O)c2ccc3OCC[C@]4(C[C@H]4C(=O)Nc4cc(ccc4CCCC(O)=O)C#N)c3c2)cn1 |r| Show InChI InChI=1S/C31H33N5O5/c1-30(2,3)36-18-22(17-33-36)34-28(39)21-9-10-26-23(14-21)31(11-12-41-26)15-24(31)29(40)35-25-13-19(16-32)7-8-20(25)5-4-6-27(37)38/h7-10,13-14,17-18,24H,4-6,11-12,15H2,1-3H3,(H,34,39)(H,35,40)(H,37,38)/t24-,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285478 (4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-5-ylc...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1ccno1)C#N |r| Show InChI InChI=1S/C27H24N4O6/c28-15-16-4-5-17(2-1-3-24(32)33)21(12-16)30-26(35)20-14-27(20)9-11-36-22-7-6-18(13-19(22)27)25(34)31-23-8-10-29-37-23/h4-8,10,12-13,20H,1-3,9,11,14H2,(H,30,35)(H,31,34)(H,32,33)/t20-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285474 (4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-3-ylc...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1ccon1)C#N |r| Show InChI InChI=1S/C27H24N4O6/c28-15-16-4-5-17(2-1-3-24(32)33)21(12-16)29-26(35)20-14-27(20)9-11-36-22-7-6-18(13-19(22)27)25(34)30-23-8-10-37-31-23/h4-8,10,12-13,20H,1-3,9,11,14H2,(H,29,35)(H,32,33)(H,30,31,34)/t20-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285495 (4-[4-Cyano-2-({[(2′R,4S)-6-(1-methyl-1H-1,2,...) Show SMILES Cn1cc(nn1)-c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C26H25N5O4/c1-31-15-22(29-30-31)18-7-8-23-19(12-18)26(9-10-35-23)13-20(26)25(34)28-21-11-16(14-27)5-6-17(21)3-2-4-24(32)33/h5-8,11-12,15,20H,2-4,9-10,13H2,1H3,(H,28,34)(H,32,33)/t20-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285462 (US10077247, Example 2-3) Show SMILES CC(C)(C)NC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C28H31N3O5/c1-27(2,3)31-25(34)19-9-10-23-20(14-19)28(11-12-36-23)15-21(28)26(35)30-22-13-17(16-29)7-8-18(22)5-4-6-24(32)33/h7-10,13-14,21H,4-6,11-12,15H2,1-3H3,(H,30,35)(H,31,34)(H,32,33)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285489 (4-[4-Cyano-2-({[(2′R,4S)-6-(6-methoxy-3-pyri...) Show SMILES COc1ccc(cn1)-c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C29H27N3O5/c1-36-26-10-8-21(17-31-26)20-7-9-25-22(14-20)29(11-12-37-25)15-23(29)28(35)32-24-13-18(16-30)5-6-19(24)3-2-4-27(33)34/h5-10,13-14,17,23H,2-4,11-12,15H2,1H3,(H,32,35)(H,33,34)/t23-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285479 (4-{4-Cyano-2-[({(2′R,4S)-6-[(1-methyl-1H-pyr...) Show SMILES Cn1nccc1NC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C28H27N5O5/c1-33-24(9-11-30-33)32-26(36)19-7-8-23-20(14-19)28(10-12-38-23)15-21(28)27(37)31-22-13-17(16-29)5-6-18(22)3-2-4-25(34)35/h5-9,11,13-14,21H,2-4,10,12,15H2,1H3,(H,31,37)(H,32,36)(H,34,35)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285471 (4-{4-Cyano-2-[({(2′R,4S)-6-[(2,2-difluoroeth...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)NCC(F)F)C#N |r| Show InChI InChI=1S/C26H25F2N3O5/c27-22(28)14-30-24(34)17-6-7-21-18(11-17)26(8-9-36-21)12-19(26)25(35)31-20-10-15(13-29)4-5-16(20)2-1-3-23(32)33/h4-7,10-11,19,22H,1-3,8-9,12,14H2,(H,30,34)(H,31,35)(H,32,33)/t19-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285486 (4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridinyl)-2,3...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1cccnc1)C#N |r| Show InChI InChI=1S/C28H25N3O4/c29-16-18-6-7-19(3-1-5-26(32)33)24(13-18)31-27(34)23-15-28(23)10-12-35-25-9-8-20(14-22(25)28)21-4-2-11-30-17-21/h2,4,6-9,11,13-14,17,23H,1,3,5,10,12,15H2,(H,31,34)(H,32,33)/t23-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285466 (4-[4-cyano-2-({[(2′R,4S)-6-(cyclopropylcarba...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)NC1CC1)C#N |r| Show InChI InChI=1S/C27H27N3O5/c28-15-16-4-5-17(2-1-3-24(31)32)22(12-16)30-26(34)21-14-27(21)10-11-35-23-9-6-18(13-20(23)27)25(33)29-19-7-8-19/h4-6,9,12-13,19,21H,1-3,7-8,10-11,14H2,(H,29,33)(H,30,34)(H,31,32)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285496 (4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridazinyl)-2...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1cccnn1)C#N |r| Show InChI InChI=1S/C27H24N4O4/c28-16-17-6-7-18(3-1-5-25(32)33)23(13-17)30-26(34)21-15-27(21)10-12-35-24-9-8-19(14-20(24)27)22-4-2-11-29-31-22/h2,4,6-9,11,13-14,21H,1,3,5,10,12,15H2,(H,30,34)(H,32,33)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285512 (4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl...) Show SMILES CNC(=O)c1ccc2c(c1)[C@@]1(C[C@H]1C(=O)Nc1cc(ccc1CCCC(O)=O)C#N)CC2(C)C |r| Show InChI InChI=1S/C27H29N3O4/c1-26(2)15-27(20-12-18(24(33)29-3)9-10-19(20)26)13-21(27)25(34)30-22-11-16(14-28)7-8-17(22)5-4-6-23(31)32/h7-12,21H,4-6,13,15H2,1-3H3,(H,29,33)(H,30,34)(H,31,32)/t21-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285508 (4-[4-Cyano-2-({[(2′R,3S)-5-(3-pyridinyl)spir...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11COc2ccc(cc12)-c1cccnc1)C#N |r| Show InChI InChI=1S/C27H23N3O4/c28-14-17-6-7-18(3-1-5-25(31)32)23(11-17)30-26(33)22-13-27(22)16-34-24-9-8-19(12-21(24)27)20-4-2-10-29-15-20/h2,4,6-12,15,22H,1,3,5,13,16H2,(H,30,33)(H,31,32)/t22-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285465 (4-{4-Cyano-2-[({(2′R,4S)-6-[(1-methyl-1H-pyr...) Show SMILES Cn1ccc(NC(=O)c2ccc3OCC[C@]4(C[C@H]4C(=O)Nc4cc(ccc4CCCC(O)=O)C#N)c3c2)n1 |r| Show InChI InChI=1S/C28H27N5O5/c1-33-11-9-24(32-33)31-26(36)19-7-8-23-20(14-19)28(10-12-38-23)15-21(28)27(37)30-22-13-17(16-29)5-6-18(22)3-2-4-25(34)35/h5-9,11,13-14,21H,2-4,10,12,15H2,1H3,(H,30,37)(H,34,35)(H,31,32,36)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285468 (4-[4 Cyano 2-({[(2′R,4S)-6-(cyclopentylcarba...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)NC1CCCC1)C#N |r| Show InChI InChI=1S/C29H31N3O5/c30-17-18-8-9-19(4-3-7-26(33)34)24(14-18)32-28(36)23-16-29(23)12-13-37-25-11-10-20(15-22(25)29)27(35)31-21-5-1-2-6-21/h8-11,14-15,21,23H,1-7,12-13,16H2,(H,31,35)(H,32,36)(H,33,34)/t23-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285469 (4-[4-Cyano-2-({[(2′R,4S)-6-(2-pyridinylcarba...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1ccccn1)C#N |r| Show InChI InChI=1S/C29H26N4O5/c30-17-18-7-8-19(4-3-6-26(34)35)23(14-18)32-28(37)22-16-29(22)11-13-38-24-10-9-20(15-21(24)29)27(36)33-25-5-1-2-12-31-25/h1-2,5,7-10,12,14-15,22H,3-4,6,11,13,16H2,(H,32,37)(H,34,35)(H,31,33,36)/t22-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285492 (4-[4-Cyano-2-({[(2′R,4S)-6-(1H-pyrrolo[2,3-b...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1cnc2[nH]ccc2c1)C#N |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285475 (US10077247, Example 2-38) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)NC1CCC1)[N+]#[C-] |r| Show InChI InChI=1S/C28H29N3O5/c1-29-20-10-8-17(4-2-7-25(32)33)23(15-20)31-27(35)22-16-28(22)12-13-36-24-11-9-18(14-21(24)28)26(34)30-19-5-3-6-19/h8-11,14-15,19,22H,2-7,12-13,16H2,(H,30,34)(H,31,35)(H,32,33)/t22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285461 (US10077247, Example 2-2) Show SMILES COCCNC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C27H29N3O6/c1-35-12-10-29-25(33)19-7-8-23-20(14-19)27(9-11-36-23)15-21(27)26(34)30-22-13-17(16-28)5-6-18(22)3-2-4-24(31)32/h5-8,13-14,21H,2-4,9-12,15H2,1H3,(H,29,33)(H,30,34)(H,31,32)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285511 (4-[4-Cyano-2-({[(1S,2R)-6′-[(2-methoxyethyl)...) Show SMILES COCCNC(=O)c1ccc2c(c1)[C@@]1(C[C@H]1C(=O)Nc1cc(ccc1CCCC(O)=O)C#N)CC2(C)C |r| Show InChI InChI=1S/C29H33N3O5/c1-28(2)17-29(22-14-20(9-10-21(22)28)26(35)31-11-12-37-3)15-23(29)27(36)32-24-13-18(16-30)7-8-19(24)5-4-6-25(33)34/h7-10,13-14,23H,4-6,11-12,15,17H2,1-3H3,(H,31,35)(H,32,36)(H,33,34)/t23-,29+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285473 (4-[4-Cyano-2-({[(2′R,4S)-6-(2-pyrimidinylcar...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)Nc1ncccn1)C#N |r| Show InChI InChI=1S/C28H25N5O5/c29-16-17-5-6-18(3-1-4-24(34)35)22(13-17)32-26(37)21-15-28(21)9-12-38-23-8-7-19(14-20(23)28)25(36)33-27-30-10-2-11-31-27/h2,5-8,10-11,13-14,21H,1,3-4,9,12,15H2,(H,32,37)(H,34,35)(H,30,31,33,36)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285494 (4-[4-Cyano-2-({[(2′R,4S)-6-(1,3-oxazol-2-yl)...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1ncco1)C#N |r| Show InChI InChI=1S/C26H23N3O5/c27-15-16-4-5-17(2-1-3-23(30)31)21(12-16)29-24(32)20-14-26(20)8-10-33-22-7-6-18(13-19(22)26)25-28-9-11-34-25/h4-7,9,11-13,20H,1-3,8,10,14H2,(H,29,32)(H,30,31)/t20-,26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285490 (4-[4-Cyano-2-({[(2′R,4S)-6-(6-methyl-3-pyrid...) Show SMILES Cc1ccc(cn1)-c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C29H27N3O4/c1-18-5-7-22(17-31-18)21-9-10-26-23(14-21)29(11-12-36-26)15-24(29)28(35)32-25-13-19(16-30)6-8-20(25)3-2-4-27(33)34/h5-10,13-14,17,24H,2-4,11-12,15H2,1H3,(H,32,35)(H,33,34)/t24-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285513 (4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl...) Show SMILES CC1(C)C[C@]2(C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)c2cc(ccc12)-c1cccnc1 |r| Show InChI InChI=1S/C30H29N3O3/c1-29(2)18-30(24-14-21(10-11-23(24)29)22-6-4-12-32-17-22)15-25(30)28(36)33-26-13-19(16-31)8-9-20(26)5-3-7-27(34)35/h4,6,8-14,17,25H,3,5,7,15,18H2,1-2H3,(H,33,36)(H,34,35)/t25-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285491 (4-[4-Cyano-2-({[(2′R,4S)-6-(6-fluoro-3-pyrid...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1ccc(F)nc1)C#N |r| Show InChI InChI=1S/C28H24FN3O4/c29-25-9-7-20(16-31-25)19-6-8-24-21(13-19)28(10-11-36-24)14-22(28)27(35)32-23-12-17(15-30)4-5-18(23)2-1-3-26(33)34/h4-9,12-13,16,22H,1-3,10-11,14H2,(H,32,35)(H,33,34)/t22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285510 (4-{4-Cyano-2-[({(2′R,3S)-5-[(2-methoxyethyl)...) Show SMILES COCCNC(=O)c1ccc2OC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C26H27N3O6/c1-34-10-9-28-24(32)18-7-8-22-19(12-18)26(15-35-22)13-20(26)25(33)29-21-11-16(14-27)5-6-17(21)3-2-4-23(30)31/h5-8,11-12,20H,2-4,9-10,13,15H2,1H3,(H,28,32)(H,29,33)(H,30,31)/t20-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285504 (4-[4-Cyano-2-({[(2′R,4S)-7-(methylcarbamoyl)...) Show SMILES CNC(=O)c1ccc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)c1 |r| Show InChI InChI=1S/C25H25N3O5/c1-27-23(31)17-7-8-18-21(12-17)33-10-9-25(18)13-19(25)24(32)28-20-11-15(14-26)5-6-16(20)3-2-4-22(29)30/h5-8,11-12,19H,2-4,9-10,13H2,1H3,(H,27,31)(H,28,32)(H,29,30)/t19-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285497 (4-[4-Cyano-2-({[(2′R,4S)-6-(5-fluoro-2-pyrid...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)-c1ccc(F)cn1)C#N |r| Show InChI InChI=1S/C28H24FN3O4/c29-20-7-8-23(31-16-20)19-6-9-25-21(13-19)28(10-11-36-25)14-22(28)27(35)32-24-12-17(15-30)4-5-18(24)2-1-3-26(33)34/h4-9,12-13,16,22H,1-3,10-11,14H2,(H,32,35)(H,33,34)/t22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285505 (4-{4-Cyano-2-[({(2′R,4S)-7-[(2-methoxyethyl)...) Show SMILES COCCNC(=O)c1ccc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)c1 |r| Show InChI InChI=1S/C27H29N3O6/c1-35-12-10-29-25(33)19-7-8-20-23(14-19)36-11-9-27(20)15-21(27)26(34)30-22-13-17(16-28)5-6-18(22)3-2-4-24(31)32/h5-8,13-14,21H,2-4,9-12,15H2,1H3,(H,29,33)(H,30,34)(H,31,32)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285477 (4-[4-Cyano-2-({[(2′R,4S)-6-(tetrahydro-2H-py...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)C(=O)NC1CCOCC1)C#N |r| Show InChI InChI=1S/C29H31N3O6/c30-17-18-4-5-19(2-1-3-26(33)34)24(14-18)32-28(36)23-16-29(23)10-13-38-25-7-6-20(15-22(25)29)27(35)31-21-8-11-37-12-9-21/h4-7,14-15,21,23H,1-3,8-13,16H2,(H,31,35)(H,32,36)(H,33,34)/t23-,29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285509 (4-[4-Cyano-2-({[(2′R,3S)-5-(methylcarbamoyl)...) Show SMILES CNC(=O)c1ccc2OC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C24H23N3O5/c1-26-22(30)16-7-8-20-17(10-16)24(13-32-20)11-18(24)23(31)27-19-9-14(12-25)5-6-15(19)3-2-4-21(28)29/h5-10,18H,2-4,11,13H2,1H3,(H,26,30)(H,27,31)(H,28,29)/t18-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285467 (4-[4-Cyano-2-({[(2′R,4S)-6-(isopropylcarbamo...) Show SMILES CC(C)NC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C27H29N3O5/c1-16(2)29-25(33)19-8-9-23-20(13-19)27(10-11-35-23)14-21(27)26(34)30-22-12-17(15-28)6-7-18(22)4-3-5-24(31)32/h6-9,12-13,16,21H,3-5,10-11,14H2,1-2H3,(H,29,33)(H,30,34)(H,31,32)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285481 (4-{4-Cyano-2-[({(2′R,4S)-6-[(2-ethoxyethyl)c...) Show SMILES CCOCCNC(=O)c1ccc2OCC[C@]3(C[C@H]3C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1 |r| Show InChI InChI=1S/C28H31N3O6/c1-2-36-13-11-30-26(34)20-8-9-24-21(15-20)28(10-12-37-24)16-22(28)27(35)31-23-14-18(17-29)6-7-19(23)4-3-5-25(32)33/h6-9,14-15,22H,2-5,10-13,16H2,1H3,(H,30,34)(H,31,35)(H,32,33)/t22-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285507 (4-{4-Cyano-2-[({(2′R,4S)-7-methoxy-6-[(2-met...) Show SMILES COCCNC(=O)c1cc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)cc1OC |r| Show InChI InChI=1S/C28H31N3O7/c1-36-11-9-30-26(34)19-13-20-24(14-23(19)37-2)38-10-8-28(20)15-21(28)27(35)31-22-12-17(16-29)6-7-18(22)4-3-5-25(32)33/h6-7,12-14,21H,3-5,8-11,15H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)/t21-,28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285501 (4-[4-Cyano-2-(({[(2′R,4S)-7-fluoro-6-(methyl...) Show SMILES CNC(=O)c1cc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)cc1F |r| Show InChI InChI=1S/C25H24FN3O5/c1-28-23(32)16-10-17-21(11-19(16)26)34-8-7-25(17)12-18(25)24(33)29-20-9-14(13-27)5-6-15(20)3-2-4-22(30)31/h5-6,9-11,18H,2-4,7-8,12H2,1H3,(H,28,32)(H,29,33)(H,30,31)/t18-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285488 (4-[4-Cyano-2-({[(2′R,4S)-6-(2-oxo-1-pyrrolid...) Show SMILES OC(=O)CCCc1ccc(cc1NC(=O)[C@@H]1C[C@]11CCOc2ccc(cc12)N1CCCC1=O)C#N |r| Show InChI InChI=1S/C27H27N3O5/c28-16-17-6-7-18(3-1-5-25(32)33)22(13-17)29-26(34)21-15-27(21)10-12-35-23-9-8-19(14-20(23)27)30-11-2-4-24(30)31/h6-9,13-14,21H,1-5,10-12,15H2,(H,29,34)(H,32,33)/t21-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM285503 (4-[4-Cyano-2-({[(2′R,4S)-7-fluoro-6-(isoprop...) Show SMILES CC(C)NC(=O)c1cc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)cc1F |r| Show InChI InChI=1S/C27H28FN3O5/c1-15(2)30-25(34)18-11-19-23(12-21(18)28)36-9-8-27(19)13-20(27)26(35)31-22-10-16(14-29)6-7-17(22)4-3-5-24(32)33/h6-7,10-12,15,20H,3-5,8-9,13H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)/t20-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	25
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...				US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN
					More data for this Ligand-Target Pair

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