Compile Data Set for Download or QSAR

Found 124 hits with Last Name = 'fujimori' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559528 (CHEMBL3950588) Show SMILES CCc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559538 (CHEMBL3908950) Show SMILES CSc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559527 (CHEMBL3907970) Show SMILES CCCc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559522 (CHEMBL3960449) Show SMILES CC(C)Oc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559524 (CHEMBL3923809) Show SMILES CCOc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559529 (CHEMBL3896936) Show SMILES Cc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559525 (CHEMBL3934976) Show SMILES COc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559523 (CHEMBL3915296) Show SMILES CCCOc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559539 (CHEMBL3980689) Show SMILES CSc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C(F)(F)F)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559526 (CHEMBL3969998) Show SMILES CC(C)c1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559517 (Remogliflozin | Remogliflozin a) Show SMILES CC(C)Oc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)nn(C(C)C)c2C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559519 (CHEMBL4786882) Show SMILES CCn1nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(Cc2ccc(OC(C)C)cc2)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552414 (CHEMBL4791592) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559537 (CHEMBL3972664) Show SMILES CCc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(SC)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559518 (CHEMBL4787524) Show SMILES CCCn1nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(Cc2ccc(OC(C)C)cc2)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50552408 (CHEMBL4750971) Show SMILES Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at rat TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Fluo-...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559532 (CHEMBL4765036) Show SMILES OC[C@H]1O[C@@H](Oc2n[nH]c3cccc(CCc4ccccc4)c23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM based ...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552420 (CHEMBL4759917) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccc(F)cc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207659 (CHEMBL3944840) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H21ClN2O3/c1-15(17-10-7-11-18(24)14-17)26(23(29)19-12-5-6-13-20(19)27)21(22(25)28)16-8-3-2-4-9-16/h2-15,21,27H,1H3,(H2,25,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552416 (CHEMBL4763262) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(F)cc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559539 (CHEMBL3980689) Show SMILES CSc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C(F)(F)F)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552411 (CHEMBL4762495) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1cccnc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552413 (CHEMBL4780270) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1N)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552412 (CHEMBL4752955) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(F)cc2F)C(=O)c1cccnc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559520 (CHEMBL4785821) Show SMILES CC(C)Oc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)nn(C)c2C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552419 (CHEMBL4785984) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccc(Cl)cc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552418 (CHEMBL4749804) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cccc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559532 (CHEMBL4765036) Show SMILES OC[C@H]1O[C@@H](Oc2n[nH]c3cccc(CCc4ccccc4)c23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559536 (CHEMBL4795938) Show SMILES CSc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C(C)C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552410 (CHEMBL4795385) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1cccnc1N)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207647 (CHEMBL3926952) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(Cl)c1 |r| Show InChI InChI=1S/C23H20ClFN2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50559535 (CHEMBL4793115) Show SMILES Cc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207568 (CHEMBL3980601) Show SMILES COC(=O)[C@H](N(Cc1cccc(OC)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H23NO4/c1-28-21-15-9-10-18(16-21)17-25(23(26)20-13-7-4-8-14-20)22(24(27)29-2)19-11-5-3-6-12-19/h3-16,22H,17H2,1-2H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552408 (CHEMBL4750971) Show SMILES Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559528 (CHEMBL3950588) Show SMILES CCc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207657 (CHEMBL3917717) Show SMILES COc1cccc(c1)[C@@H](C)N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H24N2O3/c1-17(20-14-9-15-21(16-20)29-2)26(24(28)19-12-7-4-8-13-19)22(23(25)27)18-10-5-3-6-11-18/h3-17,22H,1-2H3,(H2,25,27)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552423 (CHEMBL4748099) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccccc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552415 (CHEMBL4749601) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559529 (CHEMBL3896936) Show SMILES Cc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559527 (CHEMBL3907970) Show SMILES CCCc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559537 (CHEMBL3972664) Show SMILES CCc1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(SC)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552409 (CHEMBL4785621) Show SMILES COc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207649 (CHEMBL3907933) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H23ClN2O2/c1-16-9-6-7-14-21(16)24(29)27(17(2)19-12-8-13-20(25)15-19)22(23(26)28)18-10-4-3-5-11-18/h3-15,17,22H,1-2H3,(H2,26,28)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207658 (CHEMBL3898642) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H21ClN2O2/c1-16(19-13-8-14-20(24)15-19)26(23(28)18-11-6-3-7-12-18)21(22(25)27)17-9-4-2-5-10-17/h2-16,21H,1H3,(H2,25,27)/t16-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50559538 (CHEMBL3908950) Show SMILES CSc1ccc(Cc2c(C)[nH]nc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake				Citation and Details Article DOI: 10.1016/j.bmc.2021.116033 BindingDB Entry DOI: 10.7270/Q29G5RHZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 Show InChI InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	414	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207670 (CHEMBL3889978) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1N)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H22ClN3O2/c1-15(17-10-7-11-18(24)14-17)27(23(29)19-12-5-6-13-20(19)25)21(22(26)28)16-8-3-2-4-9-16/h2-15,21H,25H2,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair

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