Found 29 hits with Last Name = 'fujimoto' and Initial = 'y' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50006909
(2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) | PDB
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| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50049108
(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...)Show SMILES CCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H22N2O5/c1-2-5-19-23-18(13-25)20(22(28)29)24(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21(26)27/h3-4,6-11,25H,2,5,12-13H2,1H3,(H,26,27)(H,28,29) | PDB
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| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50282291
(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-hydro...)Show SMILES CCCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H24N2O5/c1-2-3-8-20-24-19(14-26)21(23(29)30)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28)(H,29,30) | PDB
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| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50009714
(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) | PDB
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50009505
(2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chlor...)Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H21ClN2O4/c1-2-3-8-18-24-20(23)19(22(28)29)25(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21(26)27/h4-7,9-12H,2-3,8,13H2,1H3,(H,26,27)(H,28,29) | PDB
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| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50282290
(3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-ethyl-5-hydro...)Show SMILES CCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C21H20N2O5/c1-2-18-22-17(12-24)19(21(27)28)23(18)11-13-7-9-14(10-8-13)15-5-3-4-6-16(15)20(25)26/h3-10,24H,2,11-12H2,1H3,(H,25,26)(H,27,28) | PDB
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| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50049119
(1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imi...)Show SMILES CCCc1nc(C(O)=O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H20N2O6/c1-2-5-17-23-18(21(27)28)19(22(29)30)24(17)12-13-8-10-14(11-9-13)15-6-3-4-7-16(15)20(25)26/h3-4,6-11H,2,5,12H2,1H3,(H,25,26)(H,27,28)(H,29,30) | PDB
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| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50399457
(CHEMBL2179400)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCCCCCCCCCC |r| Show InChI InChI=1S/C65H126N10O12S/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-41-58(77)86-48-51(87-59(78)42-28-26-24-22-20-18-16-14-12-10-8-6-4-2)49-88-50-52(70)60(79)75-57(47-76)64(83)73-54(38-30-34-44-67)62(81)71-53(37-29-33-43-66)61(80)72-55(39-31-35-45-68)63(82)74-56(65(84)85)40-32-36-46-69/h51-57,76H,3-50,66-70H2,1-2H3,(H,71,81)(H,72,80)(H,73,83)(H,74,82)(H,75,79)(H,84,85)/t51-,52+,53+,54+,55+,56+,57+/m1/s1 | PDB
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| n/a | n/a | 349 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50399457
(CHEMBL2179400)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCCCCCCCCCC |r| Show InChI InChI=1S/C65H126N10O12S/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-41-58(77)86-48-51(87-59(78)42-28-26-24-22-20-18-16-14-12-10-8-6-4-2)49-88-50-52(70)60(79)75-57(47-76)64(83)73-54(38-30-34-44-67)62(81)71-53(37-29-33-43-66)61(80)72-55(39-31-35-45-68)63(82)74-56(65(84)85)40-32-36-46-69/h51-57,76H,3-50,66-70H2,1-2H3,(H,71,81)(H,72,80)(H,73,83)(H,74,82)(H,75,79)(H,84,85)/t51-,52+,53+,54+,55+,56+,57+/m1/s1 | PDB
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| n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50003399
(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H23ClN2O3/c1-2-3-8-20-24-21(23)19(14-26)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28) | PDB
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| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50049105
(3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...)Show SMILES CCCc1nc(CO)c(C(=O)OCC)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H26N2O5/c1-3-7-21-25-20(15-27)22(24(30)31-4-2)26(21)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)23(28)29/h5-6,8-13,27H,3-4,7,14-15H2,1-2H3,(H,28,29) | PDB
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| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50461184
(CHEMBL4225423)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCNC(=O)CCCCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-13-14-15-16-18-20-22-24-38-57(78)87-46-49(88-58(79)39-44-70-56(77)37-23-21-19-17-12-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-26-30-41-66)61(82)71-51(33-25-29-40-65)60(81)72-53(35-27-31-42-67)62(83)74-54(64(85)86)36-28-32-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50461188
(CHEMBL4226256)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCNC(=O)CCCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-13-14-15-16-17-19-21-23-38-57(78)87-46-49(88-58(79)39-32-44-70-56(77)37-22-20-18-12-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461184
(CHEMBL4225423)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCNC(=O)CCCCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-13-14-15-16-18-20-22-24-38-57(78)87-46-49(88-58(79)39-44-70-56(77)37-23-21-19-17-12-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-26-30-41-66)61(82)71-51(33-25-29-40-65)60(81)72-53(35-27-31-42-67)62(83)74-54(64(85)86)36-28-32-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461188
(CHEMBL4226256)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCNC(=O)CCCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-13-14-15-16-17-19-21-23-38-57(78)87-46-49(88-58(79)39-32-44-70-56(77)37-22-20-18-12-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50282289
(1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-hydroxymethyl...)Show SMILES CCCc1cc(C(O)=O)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H23NO5/c1-2-5-17-12-20(23(28)29)21(14-25)24(17)13-15-8-10-16(11-9-15)18-6-3-4-7-19(18)22(26)27/h3-4,6-12,25H,2,5,13-14H2,1H3,(H,26,27)(H,28,29) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50049114
(4'-(4,5-Bis-hydroxymethyl-2-propyl-imidazol-1-ylme...)Show SMILES CCCc1nc(CO)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H24N2O4/c1-2-5-21-23-19(13-25)20(14-26)24(21)12-15-8-10-16(11-9-15)17-6-3-4-7-18(17)22(27)28/h3-4,6-11,25-26H,2,5,12-14H2,1H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461181
(CHEMBL4224884)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCNC(=O)CCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-10-11-12-13-14-15-16-18-22-38-57(78)87-46-49(88-58(79)39-23-19-20-32-44-70-56(77)37-21-17-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461183
(CHEMBL4226518)Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCCCNC(=O)CC)CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-6-7-8-9-10-11-12-14-18-21-24-39-58(79)88-49(46-87-57(78)38-23-20-17-15-13-16-19-22-33-44-70-56(77)4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(35-26-30-41-66)61(82)71-51(34-25-29-40-65)60(81)72-53(36-27-31-42-67)62(83)74-54(64(85)86)37-28-32-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461182
(CHEMBL4226658)Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCCNC(=O)CCC)CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-6-7-8-9-10-11-12-13-17-20-23-39-58(79)88-49(46-87-57(78)38-22-19-16-14-15-18-21-32-44-70-56(77)33-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(35-25-29-41-66)61(82)71-51(34-24-28-40-65)60(81)72-53(36-26-30-42-67)62(83)74-54(64(85)86)37-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50282288
(1-(2'-Carboxy-biphenyl-4-ylmethyl)-3-methoxymethyl...)Show SMILES CCCc1cc(COC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H25NO5/c1-3-6-19-13-18(15-30-2)22(24(28)29)25(19)14-16-9-11-17(12-10-16)20-7-4-5-8-21(20)23(26)27/h4-5,7-13H,3,6,14-15H2,1-2H3,(H,26,27)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461185
(CHEMBL4225148)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCNC(=O)CCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-12-13-14-15-16-18-20-22-38-57(78)87-46-49(88-58(79)39-27-32-44-70-56(77)37-21-19-17-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-24-29-41-66)61(82)71-51(33-23-28-40-65)60(81)72-53(35-25-30-42-67)62(83)74-54(64(85)86)36-26-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50461186
(CHEMBL4227905)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCNC(=O)CCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-12-13-14-15-16-17-19-22-38-57(78)87-46-49(88-58(79)39-23-20-32-44-70-56(77)37-21-18-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461186
(CHEMBL4227905)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCNC(=O)CCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-12-13-14-15-16-17-19-22-38-57(78)87-46-49(88-58(79)39-23-20-32-44-70-56(77)37-21-18-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50461185
(CHEMBL4225148)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCNC(=O)CCCCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-11-12-13-14-15-16-18-20-22-38-57(78)87-46-49(88-58(79)39-27-32-44-70-56(77)37-21-19-17-10-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-24-29-41-66)61(82)71-51(33-23-28-40-65)60(81)72-53(35-25-30-42-67)62(83)74-54(64(85)86)36-26-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50461181
(CHEMBL4224884)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCNC(=O)CCCCCCC |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-9-10-11-12-13-14-15-16-18-22-38-57(78)87-46-49(88-58(79)39-23-19-20-32-44-70-56(77)37-21-17-8-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461189
(CHEMBL4229084)Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCCNC(=O)CCCC)CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-8-9-10-11-12-13-14-16-20-23-39-58(79)88-49(46-87-57(78)38-22-19-17-15-18-21-32-44-70-56(77)37-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Toll-like receptor 2
(Homo sapiens (Human)) | BDBM50461187
(CHEMBL4227041)Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCCCCCCNC(=O)CCCCC)CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C64H123N11O13S/c1-3-5-7-8-9-10-11-12-13-14-15-19-23-39-58(79)88-49(46-87-57(78)38-22-18-16-17-20-32-44-70-56(77)37-21-6-4-2)47-89-48-50(69)59(80)75-55(45-76)63(84)73-52(34-25-29-41-66)61(82)71-51(33-24-28-40-65)60(81)72-53(35-26-30-42-67)62(83)74-54(64(85)86)36-27-31-43-68/h49-55,76H,3-48,65-69H2,1-2H3,(H,70,77)(H,71,82)(H,72,81)(H,73,84)(H,74,83)(H,75,80)(H,85,86)/t49-,50+,51+,52+,53+,54+,55+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University
Curated by ChEMBL
| Assay Description
Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assay |
Bioorg Med Chem Lett 28: 1638-1641 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.042
BindingDB Entry DOI: 10.7270/Q2CC139G |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Bos taurus) | BDBM50049121
(1-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...)Show SMILES CCCc1nc(C(O)=O)c(CO)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H22N2O5/c1-2-5-19-23-20(22(28)29)18(13-25)24(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21(26)27/h3-4,6-11,25H,2,5,12-13H2,1H3,(H,26,27)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of [125l]-All binding to bovine adrenal cortex |
Bioorg Med Chem Lett 4: 177-182 (1994)
Article DOI: 10.1016/S0960-894X(01)81143-4
BindingDB Entry DOI: 10.7270/Q2BG2NZQ |
More data for this
Ligand-Target Pair | |
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