BindingDB PrimarySearch

Found 35 hits with Last Name = 'fullagar' and Initial = 'jl'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50236983 (2-Hydroxy-cyclohepta-2,4,6-trienone \| 2-hydroxycyc...) Show SMILES Oc1cccccc1=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 10 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485657 (CHEMBL2146996) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335802 (4-Fluoro-N-(8-hydroxyquinolin-7-yl)benzenesulfonam...) Show SMILES Oc1c(NS(=O)(=O)c2ccc(F)cc2)ccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485648 (CHEMBL2146995) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485651 (CHEMBL2146997) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 10 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335813 (CHEMBL1650642 \| N-(8-Hydroxyquinolin-7-yl)-[1,1-bi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335814 (CHEMBL1650643 \| N-(8-Hydroxyquinolin-7-yl)thiophen...) Show SMILES Oc1c(NS(=O)(=O)c2cccs2)ccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485646 (CHEMBL2146998) Show SMILES Cc1c(O)c(=S)ccn1Cc1ccc(cc1)-c1ccc(F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485653 (CHEMBL2147001) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335807 (CHEMBL1650640 \| N-(8-Hydroxyquinolin-7-yl)benzenes...) Show SMILES Oc1c(NS(=O)(=O)c2ccccc2)ccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485647 (CHEMBL2146999) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2ccc(=S)c(O)c2C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335805 (4-Fluoro-N-(8-hydroxyquinolin-5-yl)benzenesulfonam...) Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(F)cc2)c2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335812 (CHEMBL1650639 \| N-(8-Hydroxyquinolin-5-yl)thiophen...) Show SMILES Oc1ccc(NS(=O)(=O)c2cccs2)c2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485654 (CHEMBL2147000) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335804 (CHEMBL1650636 \| N-(8-Hydroxyquinolin-5-yl)benzenes...) Show SMILES Oc1ccc(NS(=O)(=O)c2ccccc2)c2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335801 (CHEMBL1650638 \| N-(8-Hydroxyquinolin-5-yl)-[1,1'-b...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assay				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50015094 (CHEMBL152665 \| N-Hydroxy-2-phenyl-acetamide \| N-hy...) Show SMILES ONC(=O)Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485655 (CHEMBL2146994) Show SMILES ONC(=O)Cc1cccc(F)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50335808 (2,5-Dihydroxybenzoate, VI \| 2,5-dihydroxybenzoic a...) Show SMILES OC(=O)c1cc(O)ccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assay				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335806 (3-hydroxy-4H-pyran-4-thione \| CHEMBL1649594) Show SMILES Oc1coccc1=S Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485649 (CHEMBL1650620) Show SMILES Cc1c(O)c(=S)ccn1C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485656 (CHEMBL1650624) Show SMILES CCn1ccc(=S)c(O)c1C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26193 (2-Hydroxybenzoate, I \| 2-hydroxybenzoic acid \| CHE...) Show SMILES OC(=O)c1ccccc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 10 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335810 (2-thiouracil \| 4-mercaptopyrimidin-2-ol \| CHEMBL16...) Show SMILES O=c1[nH]ccc(=S)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM32203 (8-quinolinol \| CHEMBL310555 \| US10005735, Table 1....) Show SMILES Oc1cccc2cccnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50236983 (2-Hydroxy-cyclohepta-2,4,6-trienone \| 2-hydroxycyc...) Show SMILES Oc1cccccc1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50335809 (6-hydroxypicolinic acid \| CHEMBL1650602) Show SMILES OC(=O)c1cccc(=O)[nH]1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 10 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Lethal factor (Bacillus anthracis)	BDBM50335806 (3-hydroxy-4H-pyran-4-thione \| CHEMBL1649594) Show SMILES Oc1coccc1=S Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant anthrax lethal factor after 30 mins by fluorescence assay				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485652 (CHEMBL1650621) Show SMILES Cn1cccc(O)c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50335811 (3-amino-2-hydroxybenzoic acid \| CHEMBL1650630) Show SMILES Nc1cccc(C(O)=O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Elastase (Pseudomonas aeruginosa)	BDBM50485650 (CHEMBL1650623) Show SMILES CCc1c(O)c(=S)ccn1CC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at Pseudomonas aeruginosa LasB using Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide as substrate incubated for 30 mins prior to substra...				ACS Med Chem Lett 3: 668-672 (2012) Article DOI: 10.1021/ml300128f BindingDB Entry DOI: 10.7270/Q2BG2RVM
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lethal factor (Bacillus anthracis)	BDBM50099857 (ACETOHYDROXAMIC ACID (AHA) \| AHA \| Acethydroxamsae...) Show SMILES CC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.14E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of recombinant anthrax lethal factor after 30 mins by fluorescence assay				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50099857 (ACETOHYDROXAMIC ACID (AHA) \| AHA \| Acethydroxamsae...) Show SMILES CC(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.50E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins				J Med Chem 54: 591-602 (2011) Article DOI: 10.1021/jm101266s BindingDB Entry DOI: 10.7270/Q2154HBV
University of California Curated by ChEMBL					More data for this Ligand-Target Pair