Compile Data Set for Download or QSAR

Found 67 hits with Last Name = 'furnari' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383332 (CHEMBL2029786) Show SMILES CC(C)CCn1ccc(-c2ccccc2)c(C#N)c1=O Show InChI InChI=1S/C17H18N2O/c1-13(2)8-10-19-11-9-15(16(12-18)17(19)20)14-6-4-3-5-7-14/h3-7,9,11,13H,8,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.51E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383333 (CHEMBL2029787) Show SMILES COc1ccc(cc1)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H20N2O2/c1-13(2)8-10-20-11-9-16(17(12-19)18(20)21)14-4-6-15(22-3)7-5-14/h4-7,9,11,13H,8,10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383334 (CHEMBL2029788) Show SMILES COc1cccc(c1)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H20N2O2/c1-13(2)7-9-20-10-8-16(17(12-19)18(20)21)14-5-4-6-15(11-14)22-3/h4-6,8,10-11,13H,7,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383335 (CHEMBL2029789) Show SMILES COc1ccccc1-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H20N2O2/c1-13(2)8-10-20-11-9-14(16(12-19)18(20)21)15-6-4-5-7-17(15)22-3/h4-7,9,11,13H,8,10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383336 (CHEMBL2029790) Show SMILES COc1ccc(cc1F)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H19FN2O2/c1-12(2)6-8-21-9-7-14(15(11-20)18(21)22)13-4-5-17(23-3)16(19)10-13/h4-5,7,9-10,12H,6,8H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383337 (CHEMBL2029791) Show SMILES COc1ccc(cc1Cl)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H19ClN2O2/c1-12(2)6-8-21-9-7-14(15(11-20)18(21)22)13-4-5-17(23-3)16(19)10-13/h4-5,7,9-10,12H,6,8H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383338 (CHEMBL2029792) Show SMILES COc1ccc(cc1OC)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C19H22N2O3/c1-13(2)7-9-21-10-8-15(16(12-20)19(21)22)14-5-6-17(23-3)18(11-14)24-4/h5-6,8,10-11,13H,7,9H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383339 (CHEMBL2029793) Show SMILES CC(C)CCn1ccc(-c2ccc(OCC3CC3)cc2)c(C#N)c1=O Show InChI InChI=1S/C21H24N2O2/c1-15(2)9-11-23-12-10-19(20(13-22)21(23)24)17-5-7-18(8-6-17)25-14-16-3-4-16/h5-8,10,12,15-16H,3-4,9,11,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383340 (CHEMBL2029794) Show SMILES CC(C)CCn1ccc(-c2ccc(OCC3CC3)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C21H23ClN2O2/c1-14(2)7-9-24-10-8-17(18(12-23)21(24)25)16-5-6-20(19(22)11-16)26-13-15-3-4-15/h5-6,8,10-11,14-15H,3-4,7,9,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383341 (CHEMBL2029795) Show SMILES CC(C)CCn1ccc(-c2ccc(OC3CCCC3)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C22H25ClN2O2/c1-15(2)9-11-25-12-10-18(19(14-24)22(25)26)16-7-8-21(20(23)13-16)27-17-5-3-4-6-17/h7-8,10,12-13,15,17H,3-6,9,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383342 (CHEMBL2029796) Show SMILES CC(C)CCn1ccc(-c2ccc(OC3CCOCC3)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C22H25ClN2O3/c1-15(2)5-9-25-10-6-18(19(14-24)22(25)26)16-3-4-21(20(23)13-16)28-17-7-11-27-12-8-17/h3-4,6,10,13,15,17H,5,7-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	186	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383343 (CHEMBL2029805) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2)c(C#N)c1=O Show InChI InChI=1S/C23H23N3O2/c1-16(2)9-12-26-13-10-21(22(15-24)23(26)27)18-4-6-19(7-5-18)28-20-8-11-25-17(3)14-20/h4-8,10-11,13-14,16H,9,12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	447	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383344 (CHEMBL2029806) Show SMILES Cc1cc(Oc2ccc(cc2)-c2ccn(CC3CCC3)c(=O)c2C#N)ccn1 Show InChI InChI=1S/C23H21N3O2/c1-16-13-20(9-11-25-16)28-19-7-5-18(6-8-19)21-10-12-26(15-17-3-2-4-17)23(27)22(21)14-24/h5-13,17H,2-4,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383345 (CHEMBL2029807) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H21N3O2/c1-3-4-12-25-13-10-20(21(15-23)22(25)26)17-5-7-18(8-6-17)27-19-9-11-24-16(2)14-19/h5-11,13-14H,3-4,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383346 (CHEMBL2029808) Show SMILES Cc1cc(Oc2ccc(cc2)-c2ccn(CC3CC3)c(=O)c2C#N)ccn1 Show InChI InChI=1S/C22H19N3O2/c1-15-12-19(8-10-24-15)27-18-6-4-17(5-7-18)20-9-11-25(14-16-2-3-16)22(26)21(20)13-23/h4-12,16H,2-3,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	832	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383347 (CHEMBL2029809) Show SMILES CCCCn1ccc(-c2ccc(Oc3cccnc3C)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H21N3O2/c1-3-4-13-25-14-11-19(20(15-23)22(25)26)17-7-9-18(10-8-17)27-21-6-5-12-24-16(21)2/h5-12,14H,3-4,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383348 (CHEMBL2029810) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3cccnc3C)cc2)c(C#N)c1=O Show InChI InChI=1S/C23H23N3O2/c1-16(2)10-13-26-14-11-20(21(15-24)23(26)27)18-6-8-19(9-7-18)28-22-5-4-12-25-17(22)3/h4-9,11-12,14,16H,10,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	275	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383349 (CHEMBL2029811) Show SMILES Cc1ncccc1Oc1ccc(cc1)-c1ccn(CC2CC2)c(=O)c1C#N Show InChI InChI=1S/C22H19N3O2/c1-15-21(3-2-11-24-15)27-18-8-6-17(7-9-18)19-10-12-25(14-16-4-5-16)22(26)20(19)13-23/h2-3,6-12,16H,4-5,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383350 (CHEMBL2029812) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccc(C)nc3C)cc2)c(C#N)c1=O Show InChI InChI=1S/C23H23N3O2/c1-4-5-13-26-14-12-20(21(15-24)23(26)27)18-7-9-19(10-8-18)28-22-11-6-16(2)25-17(22)3/h6-12,14H,4-5,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383351 (CHEMBL2029813) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccc(C)nc3C)cc2)c(C#N)c1=O Show InChI InChI=1S/C24H25N3O2/c1-16(2)11-13-27-14-12-21(22(15-25)24(27)28)19-6-8-20(9-7-19)29-23-10-5-17(3)26-18(23)4/h5-10,12,14,16H,11,13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383352 (CHEMBL2029814) Show SMILES Cc1ccc(Oc2ccc(cc2)-c2ccn(CC3CC3)c(=O)c2C#N)c(C)n1 Show InChI InChI=1S/C23H21N3O2/c1-15-3-10-22(16(2)25-15)28-19-8-6-18(7-9-19)20-11-12-26(14-17-4-5-17)23(27)21(20)13-24/h3,6-12,17H,4-5,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	263	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383353 (CHEMBL2029815) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C22H20ClN3O2/c1-3-4-10-26-11-8-18(19(14-24)22(26)27)16-5-6-21(20(23)13-16)28-17-7-9-25-15(2)12-17/h5-9,11-13H,3-4,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	166	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383354 (CHEMBL2029798) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccccn3)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H21N3O2/c1-16(2)10-13-25-14-11-19(20(15-23)22(25)26)17-6-8-18(9-7-17)27-21-5-3-4-12-24-21/h3-9,11-12,14,16H,10,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383355 (CHEMBL2029799) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3cccnc3)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H21N3O2/c1-16(2)9-12-25-13-10-20(21(14-23)22(25)26)17-5-7-18(8-6-17)27-19-4-3-11-24-15-19/h3-8,10-11,13,15-16H,9,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383356 (CHEMBL2029800) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccncc3)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H21N3O2/c1-16(2)9-13-25-14-10-20(21(15-23)22(25)26)17-3-5-18(6-4-17)27-19-7-11-24-12-8-19/h3-8,10-12,14,16H,9,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383357 (CHEMBL2029801) Show SMILES CNc1ccc(cc1)-c1ccn(CCC(C)C)c(=O)c1C#N Show InChI InChI=1S/C18H21N3O/c1-13(2)8-10-21-11-9-16(17(12-19)18(21)22)14-4-6-15(20-3)7-5-14/h4-7,9,11,13,20H,8,10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383358 (CHEMBL2029802) Show SMILES CC(C)CCn1ccc(-c2ccc(NC3CCOCC3)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C22H26ClN3O2/c1-15(2)5-9-26-10-6-18(19(14-24)22(26)27)16-3-4-21(20(23)13-16)25-17-7-11-28-12-8-17/h3-4,6,10,13,15,17,25H,5,7-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383359 (CHEMBL2029803) Show SMILES CC(C)CCn1ccc(-c2ccc(cc2)N2CCOCC2)c(C#N)c1=O Show InChI InChI=1S/C21H25N3O2/c1-16(2)7-9-24-10-8-19(20(15-22)21(24)25)17-3-5-18(6-4-17)23-11-13-26-14-12-23/h3-6,8,10,16H,7,9,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383360 (CHEMBL2029804) Show SMILES CC(C)CCn1ccc(-c2ccc(Nc3ccncc3)cc2)c(C#N)c1=O Show InChI InChI=1S/C22H22N4O/c1-16(2)9-13-26-14-10-20(21(15-23)22(26)27)17-3-5-18(6-4-17)25-19-7-11-24-12-8-19/h3-8,10-12,14,16H,9,13H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383361 (CHEMBL2029816) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2Cl)c(C#N)c1=O Show InChI InChI=1S/C22H20ClN3O2/c1-3-4-10-26-11-8-18(20(14-24)22(26)27)19-6-5-16(13-21(19)23)28-17-7-9-25-15(2)12-17/h5-9,11-13H,3-4,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	933	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383362 (CHEMBL2029817) Show SMILES CCCCn1ccc(-c2ccc(Oc3cccnc3C)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C22H20ClN3O2/c1-3-4-11-26-12-9-17(18(14-24)22(26)27)16-7-8-21(19(23)13-16)28-20-6-5-10-25-15(20)2/h5-10,12-13H,3-4,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383363 (CHEMBL2029818) Show SMILES Cc1ncccc1Oc1ccc(cc1Cl)-c1ccn(CC2CC2)c(=O)c1C#N Show InChI InChI=1S/C22H18ClN3O2/c1-14-20(3-2-9-25-14)28-21-7-6-16(11-19(21)23)17-8-10-26(13-15-4-5-15)22(27)18(17)12-24/h2-3,6-11,15H,4-5,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383364 (CHEMBL2029819) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccc(C)nc3C)c(Cl)c2)c(C#N)c1=O Show InChI InChI=1S/C23H22ClN3O2/c1-4-5-11-27-12-10-18(19(14-25)23(27)28)17-7-9-22(20(24)13-17)29-21-8-6-15(2)26-16(21)3/h6-10,12-13H,4-5,11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383365 (CHEMBL2029820) Show SMILES Cc1ccc(Oc2ccc(cc2Cl)-c2ccn(CC3CC3)c(=O)c2C#N)c(C)n1 Show InChI InChI=1S/C23H20ClN3O2/c1-14-3-7-21(15(2)26-14)29-22-8-6-17(11-20(22)24)18-9-10-27(13-16-4-5-16)23(28)19(18)12-25/h3,6-11,16H,4-5,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383366 (CHEMBL2029821) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)c(F)c2)c(C#N)c1=O Show InChI InChI=1S/C22H20FN3O2/c1-3-4-10-26-11-8-18(19(14-24)22(26)27)16-5-6-21(20(23)13-16)28-17-7-9-25-15(2)12-17/h5-9,11-13H,3-4,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383367 (CHEMBL2029822) Show SMILES CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2F)c(C#N)c1=O Show InChI InChI=1S/C22H20FN3O2/c1-3-4-10-26-11-8-18(20(14-24)22(26)27)19-6-5-16(13-21(19)23)28-17-7-9-25-15(2)12-17/h5-9,11-13H,3-4,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383368 (CHEMBL2029823) Show SMILES CCCCn1ccc(-c2ccc(Oc3cc(C)nc(C)c3)c(F)c2)c(C#N)c1=O Show InChI InChI=1S/C23H22FN3O2/c1-4-5-9-27-10-8-19(20(14-25)23(27)28)17-6-7-22(21(24)13-17)29-18-11-15(2)26-16(3)12-18/h6-8,10-13H,4-5,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	372	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383369 (CHEMBL2029797) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccccc3)cc2)c(C#N)c1=O Show InChI InChI=1S/C23H22N2O2/c1-17(2)12-14-25-15-13-21(22(16-24)23(25)26)18-8-10-20(11-9-18)27-19-6-4-3-5-7-19/h3-11,13,15,17H,12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417815 (CHEMBL1669391) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1cnc(OC)c(F)c1 Show InChI InChI=1S/C18H16ClFN2O2/c1-3-5-22-6-4-11-7-12(8-14(19)16(11)18(22)23)13-9-15(20)17(24-2)21-10-13/h4,6-10H,3,5H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417816 (CHEMBL1669392) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(Oc2ccccc2)nc1 Show InChI InChI=1S/C23H19ClN2O2/c1-2-11-26-12-10-16-13-18(14-20(24)22(16)23(26)27)17-8-9-21(25-15-17)28-19-6-4-3-5-7-19/h3-10,12-15H,2,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417817 (CHEMBL1669393) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCCc2ccccc2)nc1 Show InChI InChI=1S/C25H23ClN2O2/c1-2-12-28-13-10-19-15-21(16-22(26)24(19)25(28)29)20-8-9-23(27-17-20)30-14-11-18-6-4-3-5-7-18/h3-10,13,15-17H,2,11-12,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417818 (CHEMBL1669394) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCc2cccnc2)nc1 Show InChI InChI=1S/C23H20ClN3O2/c1-2-9-27-10-7-17-11-19(12-20(24)22(17)23(27)28)18-5-6-21(26-14-18)29-15-16-4-3-8-25-13-16/h3-8,10-14H,2,9,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417819 (CHEMBL1669395) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C19H18ClNO2/c1-3-9-21-10-8-14-11-15(12-17(20)18(14)19(21)22)13-4-6-16(23-2)7-5-13/h4-8,10-12H,3,9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417820 (CHEMBL1669396) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H20ClNO2/c1-2-13-26-14-12-18-15-19(16-22(25)23(18)24(26)27)17-8-10-21(11-9-17)28-20-6-4-3-5-7-20/h3-12,14-16H,2,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417821 (CHEMBL1669397) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C23H19ClN2O2/c1-2-12-26-13-9-17-14-18(15-21(24)22(17)23(26)27)16-3-5-19(6-4-16)28-20-7-10-25-11-8-20/h3-11,13-15H,2,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417822 (CHEMBL1669398) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCc2cccnc2)cc1 Show InChI InChI=1S/C24H21ClN2O2/c1-2-11-27-12-9-19-13-20(14-22(25)23(19)24(27)28)18-5-7-21(8-6-18)29-16-17-4-3-10-26-15-17/h3-10,12-15H,2,11,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417823 (CHEMBL1669399) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCc2ccc(Cl)nc2)cc1 Show InChI InChI=1S/C24H20Cl2N2O2/c1-2-10-28-11-9-18-12-19(13-21(25)23(18)24(28)29)17-4-6-20(7-5-17)30-15-16-3-8-22(26)27-14-16/h3-9,11-14H,2,10,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417824 (CHEMBL1669400) Show SMILES CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCc2ccc(nc2)C(F)(F)F)cc1 Show InChI InChI=1S/C25H20ClF3N2O2/c1-2-10-31-11-9-18-12-19(13-21(26)23(18)24(31)32)17-4-6-20(7-5-17)33-15-16-3-8-22(30-14-16)25(27,28)29/h3-9,11-14H,2,10,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417825 (CHEMBL1669401) Show SMILES CCCn1ccc2cc(ccc2c1=O)N1CCOCC1 Show InChI InChI=1S/C16H20N2O2/c1-2-6-18-7-5-13-12-14(3-4-15(13)16(18)19)17-8-10-20-11-9-17/h3-5,7,12H,2,6,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417826 (CHEMBL1669402) Show SMILES CCCn1ccc2cc(ccc2c1=O)-c1cccnc1 Show InChI InChI=1S/C17H16N2O/c1-2-9-19-10-7-14-11-13(5-6-16(14)17(19)20)15-4-3-8-18-12-15/h3-8,10-12H,2,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 67 total )  |  Next  |  Last  >>

Jump to: