Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247405 (US9452985, THK-5125) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.20 | -45.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247403 (US9452985, THK-5117) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 10.5 | -45.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247407 (US9452985, THK-5129) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 21.4 | -43.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247404 (US9452985, THK-5122) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 34.9 | -42.6 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247402 (US9452985, THK-5116) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 36 | -42.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247406 (US9452985, THK-5151) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 40.1 | -42.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM247408 (US9452985, THK-523 (reference for comparison)) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 59.3 | -41.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microtubule-associated protein tau (Homo sapiens (Human)) | BDBM50185987 (2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | US Patent | 256 | -37.6 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
GE Healthcare Limited US Patent | Assay Description For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a... | US Patent US9452985 (2016) BindingDB Entry DOI: 10.7270/Q2FB51VM | |||||||||||
More data for this Ligand-Target Pair |