| Reaction Details |
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 | Report a problem with these data |
| Target | Microtubule-associated protein tau |
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| Ligand | BDBM247406 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Binding Assay |
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| Temperature | 298.15±n/a K |
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| Ki | 40.1±n/a nM |
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| Comments | extracted |
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| Citation |  Kudo, Y; Furumoto, S; Okamura, N Tau imaging probe US Patent US9452985 Publication Date 9/27/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Microtubule-associated protein tau |
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| Name: | Microtubule-associated protein tau |
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| Synonyms: | MAPT | MAPTL | MTBT1 | Microtubule-associated protein tau | Neurofibrillary tangle protein | PHF-tau | Paired helical filament-tau | TAU | TAU_HUMAN | Tau Protein |
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| Type: | Protein |
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| Mol. Mass.: | 78928.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10636 |
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| Residue: | 758 |
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| Sequence: | MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
DPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP
KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD
LSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEK
LDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDT
SPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
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| BDBM247406 |
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| n/a |
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| Name | BDBM247406 |
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| Synonyms: | US9452985, THK-5151 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18FN3O2 |
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| Mol. Mass. | 327.3528 |
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| SMILES | CNc1ccc(cn1)-c1ccc2cc(OCC(O)CF)ccc2n1 |
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| Structure | 
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