Compile Data Set for Download or QSAR

Found 202 hits with Last Name = 'gómez' and Initial = 'la'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131579 (4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-ben...) Show SMILES CCOc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16ClN3O3S/c1-2-24-14-7-3-12(4-8-14)16-17(18)20-11-21(16)13-5-9-15(10-6-13)25(19,22)23/h3-11H,2H2,1H3,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cells				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131567 (4-[4-Chloro-5-(3,5-dichloro-phenyl)-imidazol-1-yl]...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C15H10Cl3N3O2S/c16-10-5-9(6-11(17)7-10)14-15(18)20-8-21(14)12-1-3-13(4-2-12)24(19,22)23/h1-8H,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cells				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía. S.A. Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma				J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131569 (4-(4-Chloro-5-p-tolyl-imidazol-1-yl)-benzenesulfon...) Show SMILES Cc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H14ClN3O2S/c1-11-2-4-12(5-3-11)15-16(17)19-10-20(15)13-6-8-14(9-7-13)23(18,21)22/h2-10H,1H3,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131585 (4-Chloro-5-(4-ethoxy-phenyl)-1-(4-methanesulfonyl-...) Show SMILES CCOc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H17ClN2O3S/c1-3-24-15-8-4-13(5-9-15)17-18(19)20-12-21(17)14-6-10-16(11-7-14)25(2,22)23/h4-12H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131622 (4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-1-(4-methan...) Show SMILES COc1ccc(cc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H14ClFN2O3S/c1-24-15-8-3-11(9-14(15)19)16-17(18)20-10-21(16)12-4-6-13(7-5-12)25(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131646 (4-[4-Chloro-5-(3-chloro-4-methoxy-phenyl)-imidazol...) Show SMILES COc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H13Cl2N3O3S/c1-24-14-7-2-10(8-13(14)17)15-16(18)20-9-21(15)11-3-5-12(6-4-11)25(19,22)23/h2-9H,1H3,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131593 (4-[4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-imidazol...) Show SMILES COc1ccc(cc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H13ClFN3O3S/c1-24-14-7-2-10(8-13(14)18)15-16(17)20-9-21(15)11-3-5-12(6-4-11)25(19,22)23/h2-9H,1H3,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131608 (4-Chloro-5-(2,3-dichloro-phenyl)-1-(4-methanesulfo...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1cccc(Cl)c1Cl |(14.99,-4.85,;13.47,-5.19,;13.82,-6.69,;13.14,-3.68,;11.97,-5.52,;10.92,-4.4,;9.42,-4.75,;8.96,-6.22,;10.01,-7.35,;11.51,-7.01,;7.46,-6.57,;6.93,-8,;5.41,-7.93,;4.99,-6.46,;3.65,-5.69,;6.27,-5.61,;6.27,-4.05,;4.94,-3.28,;4.94,-1.74,;6.27,-.97,;7.6,-1.74,;8.94,-.96,;7.6,-3.28,;8.94,-4.07,)| Show InChI InChI=1S/C16H11Cl3N2O2S/c1-24(22,23)11-7-5-10(6-8-11)21-9-20-16(19)15(21)12-3-2-4-13(17)14(12)18/h2-9H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131604 (5-Benzo[1,3]dioxol-5-yl-4-chloro-1-(4-methanesulfo...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc2OCOc2c1 Show InChI InChI=1S/C17H13ClN2O4S/c1-25(21,22)13-5-3-12(4-6-13)20-9-19-17(18)16(20)11-2-7-14-15(8-11)24-10-23-14/h2-9H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131602 (4-Chloro-5-(3-fluoro-4-methyl-phenyl)-1-(4-methane...) Show SMILES Cc1ccc(cc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H14ClFN2O2S/c1-11-3-4-12(9-15(11)19)16-17(18)20-10-21(16)13-5-7-14(8-6-13)24(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131650 (4-Chloro-5-(2,4-difluoro-phenyl)-1-(4-methanesulfo...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(F)cc1F |(14.99,-4.85,;13.47,-5.19,;13.82,-6.69,;13.14,-3.68,;11.97,-5.52,;10.92,-4.4,;9.42,-4.75,;8.96,-6.22,;10.01,-7.35,;11.51,-7.01,;7.46,-6.57,;6.93,-8,;5.41,-7.93,;4.99,-6.46,;3.65,-5.69,;6.27,-5.61,;6.27,-4.05,;4.94,-3.28,;4.94,-1.74,;6.27,-.97,;6.27,.58,;7.6,-1.74,;7.6,-3.28,;8.94,-4.07,)| Show InChI InChI=1S/C16H11ClF2N2O2S/c1-24(22,23)12-5-3-11(4-6-12)21-9-20-16(17)15(21)13-7-2-10(18)8-14(13)19/h2-9H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131591 (4-Chloro-5-(3-chloro-4-ethoxy-phenyl)-1-(4-methane...) Show SMILES CCOc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H16Cl2N2O3S/c1-3-25-16-9-4-12(10-15(16)19)17-18(20)21-11-22(17)13-5-7-14(8-6-13)26(2,23)24/h4-11H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131614 (4-[4-Chloro-5-(3-chloro-4-ethoxy-phenyl)-imidazol-...) Show SMILES CCOc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15Cl2N3O3S/c1-2-25-15-8-3-11(9-14(15)18)16-17(19)21-10-22(16)12-4-6-13(7-5-12)26(20,23)24/h3-10H,2H2,1H3,(H2,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131611 (4-Chloro-5-(3,5-dichloro-4-methoxy-phenyl)-1-(4-me...) Show SMILES COc1c(Cl)cc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H13Cl3N2O3S/c1-25-16-13(18)7-10(8-14(16)19)15-17(20)21-9-22(15)11-3-5-12(6-4-11)26(2,23)24/h3-9H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131616 (4-Chloro-5-(3-chloro-4-methoxy-phenyl)-1-(4-methan...) Show SMILES COc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H14Cl2N2O3S/c1-24-15-8-3-11(9-14(15)18)16-17(19)20-10-21(16)12-4-6-13(7-5-12)25(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131647 (4-[4-Chloro-5-(4-fluoro-3-methoxy-phenyl)-imidazol...) Show SMILES COc1cc(ccc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H13ClFN3O3S/c1-24-14-8-10(2-7-13(14)18)15-16(17)20-9-21(15)11-3-5-12(6-4-11)25(19,22)23/h2-9H,1H3,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131621 (4-Chloro-5-(2,3-dihydro-benzofuran-5-yl)-1-(4-meth...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc2OCCc2c1 Show InChI InChI=1S/C18H15ClN2O3S/c1-25(22,23)15-5-3-14(4-6-15)21-11-20-18(19)17(21)13-2-7-16-12(10-13)8-9-24-16/h2-7,10-11H,8-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131586 (4-(4-Chloro-5-phenyl-imidazol-1-yl)-benzenesulfona...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccccc1 Show InChI InChI=1S/C15H12ClN3O2S/c16-15-14(11-4-2-1-3-5-11)19(10-18-15)12-6-8-13(9-7-12)22(17,20)21/h1-10H,(H2,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía. S.A. Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells				J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131619 (4-Chloro-1-(4-methanesulfonyl-phenyl)-5-(4-methoxy...) Show SMILES COc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H15ClN2O3S/c1-23-14-7-3-12(4-8-14)16-17(18)19-11-20(16)13-5-9-15(10-6-13)24(2,21)22/h3-11H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131588 (4-Chloro-5-(4-chloro-3-methyl-phenyl)-1-(4-methane...) Show SMILES Cc1cc(ccc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H14Cl2N2O2S/c1-11-9-12(3-8-15(11)18)16-17(19)20-10-21(16)13-4-6-14(7-5-13)24(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131648 (4-Chloro-1-(4-methanesulfonyl-phenyl)-5-(4-methyls...) Show SMILES CSc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H15ClN2O2S2/c1-23-14-7-3-12(4-8-14)16-17(18)19-11-20(16)13-5-9-15(10-6-13)24(2,21)22/h3-11H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cells				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50102309 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-7...) Show SMILES Cc1ccnc2c(c(nn12)-c1ccc(cc1)S(C)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C20H16FN3O2S/c1-13-11-12-22-20-18(14-3-7-16(21)8-4-14)19(23-24(13)20)15-5-9-17(10-6-15)27(2,25)26/h3-12H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía. S.A. Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells				J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50102311 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...) Show SMILES Cc1cnc2c(c(nn2c1C)-c1ccc(cc1)S(C)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C21H18FN3O2S/c1-13-12-23-21-19(15-4-8-17(22)9-5-15)20(24-25(21)14(13)2)16-6-10-18(11-7-16)28(3,26)27/h4-12H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía. S.A. Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells				J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131632 (4-Chloro-1-(4-methanesulfonyl-phenyl)-5-(4-methoxy...) Show SMILES COc1ccc(cc1C)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H17ClN2O3S/c1-12-10-13(4-9-16(12)24-2)17-18(19)20-11-21(17)14-5-7-15(8-6-14)25(3,22)23/h4-11H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131590 (4-Chloro-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(F)cc1 Show InChI InChI=1S/C16H12ClFN2O2S/c1-23(21,22)14-8-6-13(7-9-14)20-10-19-16(17)15(20)11-2-4-12(18)5-3-11/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131596 (2-Chloro-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(Cl)n1-c1ccc(F)cc1 Show InChI InChI=1S/C16H12ClFN2O2S/c1-23(21,22)14-8-2-11(3-9-14)15-10-19-16(17)20(15)13-6-4-12(18)5-7-13/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131638 (4-Chloro-5-(2-fluoro-4-methoxy-phenyl)-1-(4-methan...) Show SMILES COc1ccc(-c2c(Cl)ncn2-c2ccc(cc2)S(C)(=O)=O)c(F)c1 |(4.93,1.36,;6.27,.58,;6.27,-.97,;4.94,-1.74,;4.94,-3.28,;6.27,-4.05,;6.27,-5.61,;4.98,-6.46,;3.65,-5.69,;5.4,-7.93,;6.92,-8,;7.46,-6.57,;8.96,-6.22,;9.42,-4.75,;10.92,-4.4,;11.96,-5.52,;11.5,-7.01,;10.01,-7.34,;13.47,-5.19,;14.98,-4.84,;13.82,-6.69,;13.13,-3.68,;7.6,-3.28,;8.93,-4.07,;7.6,-1.74,)| Show InChI InChI=1S/C17H14ClFN2O3S/c1-24-12-5-8-14(15(19)9-12)16-17(18)20-10-21(16)11-3-6-13(7-4-11)25(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131633 (4-Chloro-1-(4-methanesulfonyl-phenyl)-5-(3-methoxy...) Show SMILES COc1cc(ccc1C)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H17ClN2O3S/c1-12-4-5-13(10-16(12)24-2)17-18(19)20-11-21(17)14-6-8-15(9-7-14)25(3,22)23/h4-11H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131618 (4-Chloro-1-(4-methanesulfonyl-phenyl)-5-p-tolyl-1H...) Show SMILES Cc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H15ClN2O2S/c1-12-3-5-13(6-4-12)16-17(18)19-11-20(16)14-7-9-15(10-8-14)23(2,21)22/h3-11H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131644 (4-Chloro-5-(4-fluoro-3-methoxy-phenyl)-1-(4-methan...) Show SMILES COc1cc(ccc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H14ClFN2O3S/c1-24-15-9-11(3-8-14(15)19)16-17(18)20-10-21(16)12-4-6-13(7-5-12)25(2,22)23/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131624 (4-[4-Chloro-5-(4-fluoro-phenyl)-imidazol-1-yl]-ben...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(F)cc1 Show InChI InChI=1S/C15H11ClFN3O2S/c16-15-14(10-1-3-11(17)4-2-10)20(9-19-15)12-5-7-13(8-6-12)23(18,21)22/h1-9H,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131627 (4-Chloro-5-(4-chloro-phenyl)-1-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2O2S/c1-23(21,22)14-8-6-13(7-9-14)20-10-19-16(18)15(20)11-2-4-12(17)5-3-11/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131645 (4-[4-Chloro-5-(4-ethoxy-3-fluoro-phenyl)-imidazol-...) Show SMILES CCOc1ccc(cc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15ClFN3O3S/c1-2-25-15-8-3-11(9-14(15)19)16-17(18)21-10-22(16)12-4-6-13(7-5-12)26(20,23)24/h3-10H,2H2,1H3,(H2,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131577 (4-Chloro-5-(4-ethoxy-3-fluoro-phenyl)-1-(4-methane...) Show SMILES CCOc1ccc(cc1F)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H16ClFN2O3S/c1-3-25-16-9-4-12(10-15(16)20)17-18(19)21-11-22(17)13-5-7-14(8-6-13)26(2,23)24/h4-11H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131587 (CHEMBL324048 | {2-Chloro-4-[5-chloro-3-(4-methanes...) Show SMILES CN(C)c1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H17Cl2N3O2S/c1-22(2)16-9-4-12(10-15(16)19)17-18(20)21-11-23(17)13-5-7-14(8-6-13)26(3,24)25/h4-11H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131579 (4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-ben...) Show SMILES CCOc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H16ClN3O3S/c1-2-24-14-7-3-12(4-8-14)16-17(18)20-11-21(16)13-5-9-15(10-6-13)25(19,22)23/h3-11H,2H2,1H3,(H2,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131581 (4-Chloro-5-(2-fluoro-phenyl)-1-(4-methanesulfonyl-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccccc1F |(15.11,-4.85,;13.59,-5.19,;13.94,-6.69,;13.26,-3.68,;12.09,-5.53,;11.04,-4.4,;9.54,-4.75,;9.08,-6.23,;10.13,-7.35,;11.63,-7.01,;7.58,-6.57,;7.05,-8,;5.53,-7.93,;5.11,-6.46,;3.77,-5.69,;6.39,-5.61,;6.39,-4.05,;5.06,-3.28,;5.06,-1.74,;6.39,-.97,;7.72,-1.74,;7.72,-3.28,;9.06,-4.05,)| Show InChI InChI=1S/C16H12ClFN2O2S/c1-23(21,22)12-8-6-11(7-9-12)20-10-19-16(17)15(20)13-4-2-3-5-14(13)18/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131631 (CHEMBL331278 | [1-(4-Fluoro-phenyl)-5-(4-methanesu...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(C(=O)c2ccccc2)n1-c1ccc(F)cc1 Show InChI InChI=1S/C23H17FN2O3S/c1-30(28,29)20-13-7-16(8-14-20)21-15-25-23(22(27)17-5-3-2-4-6-17)26(21)19-11-9-18(24)10-12-19/h2-15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131592 (4-Bromo-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-p...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Br)c1-c1ccc(F)cc1 Show InChI InChI=1S/C16H12BrFN2O2S/c1-23(21,22)14-8-6-13(7-9-14)20-10-19-16(17)15(20)11-2-4-12(18)5-3-11/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131615 (4-Chloro-5-(4-isopropyl-phenyl)-1-(4-methanesulfon...) Show SMILES CC(C)c1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H19ClN2O2S/c1-13(2)14-4-6-15(7-5-14)18-19(20)21-12-22(18)16-8-10-17(11-9-16)25(3,23)24/h4-13H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131629 (4-[4-Chloro-5-(6-chloro-pyridin-3-yl)-imidazol-1-y...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc(Cl)nc1 Show InChI InChI=1S/C14H10Cl2N4O2S/c15-12-6-1-9(7-18-12)13-14(16)19-8-20(13)10-2-4-11(5-3-10)23(17,21)22/h1-8H,(H2,17,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131606 (4-Chloro-3-[5-chloro-3-(4-methanesulfonyl-phenyl)-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1cnccc1Cl |(15.2,-4.77,;13.68,-5.12,;14.03,-6.63,;13.35,-3.6,;12.18,-5.46,;11.14,-4.32,;9.64,-4.67,;9.18,-6.14,;10.23,-7.28,;11.72,-6.94,;7.68,-6.49,;7.15,-7.93,;5.63,-7.86,;5.21,-6.38,;3.88,-5.61,;6.49,-5.54,;6.49,-3.99,;7.82,-3.22,;7.82,-1.66,;6.49,-.89,;5.16,-1.66,;5.16,-3.22,;3.83,-4,)| Show InChI InChI=1S/C15H11Cl2N3O2S/c1-23(21,22)11-4-2-10(3-5-11)20-9-19-15(17)14(20)12-8-18-7-6-13(12)16/h2-9H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131600 (2-Bromo-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-p...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(Br)n1-c1ccc(F)cc1 Show InChI InChI=1S/C16H12BrFN2O2S/c1-23(21,22)14-8-2-11(3-9-14)15-10-19-16(17)20(15)13-6-4-12(18)5-7-13/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131601 (1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...) Show SMILES Cc1ncc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C17H15FN2O2S/c1-12-19-11-17(20(12)15-7-5-14(18)6-8-15)13-3-9-16(10-4-13)23(2,21)22/h3-11H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50131578 (1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(C#N)n1-c1ccc(F)cc1 Show InChI InChI=1S/C17H12FN3O2S/c1-24(22,23)15-8-2-12(3-9-15)16-11-20-17(10-19)21(16)14-6-4-13(18)5-7-14/h2-9,11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Domp&egrove; pha.r.ma s.p.a. Curated by ChEMBL					Assay Description In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determined				J Med Chem 46: 3463-75 (2003) Article DOI: 10.1021/jm030765s BindingDB Entry DOI: 10.7270/Q2HQ3Z98
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 202 total )  |  Next  |  Last  >>

Jump to: