Compile Data Set for Download or QSAR

Found 17 hits with Last Name = 'gallagher' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50025695 (3-Allyl-1-(4-hydroxy-phenyl)-6-methyl-2,3,4,5-tetr...) Show SMILES Cc1c(O)c(O)cc2C(CN(CC=C)CCc12)c1ccc(O)cc1 Show InChI InChI=1S/C20H23NO3/c1-3-9-21-10-8-16-13(2)20(24)19(23)11-17(16)18(12-21)14-4-6-15(22)7-5-14/h3-7,11,18,22-24H,1,8-10,12H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of the constrictor response to electrical stimulation in an isolated perfused rab...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50225360 (CHEMBL39845) Show SMILES CCCN(CCC)CCc1cccc(O)c1 Show InChI InChI=1S/C14H23NO/c1-3-9-15(10-4-2)11-8-13-6-5-7-14(16)12-13/h5-7,12,16H,3-4,8-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004918 ((+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50019389 (3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12 Show InChI InChI=1S/C19H20ClNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of release of NE in an isolated perfused rabbit ear artery preparation				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50025697 (3-Allyl-1-(4-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2cc(O)c(O)cc12 Show InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-14-10-18(22)19(23)11-16(14)17(12-20)13-3-5-15(21)6-4-13/h2-6,10-11,17,21-23H,1,7-9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50025698 (3-Allyl-6-fluoro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(F)c(O)c(O)cc12 Show InChI InChI=1S/C19H20FNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50025698 (3-Allyl-6-fluoro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(F)c(O)c(O)cc12 Show InChI InChI=1S/C19H20FNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	137	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of the constrictor response to electrical stimulation in an isolated perfused rab...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50025697 (3-Allyl-1-(4-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2cc(O)c(O)cc12 Show InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-14-10-18(22)19(23)11-16(14)17(12-20)13-3-5-15(21)6-4-13/h2-6,10-11,17,21-23H,1,7-9,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	253	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of the constrictor response to electrical stimulation in an isolated perfused rab...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50019389 (3-Allyl-6-chloro-1-(4-hydroxy-phenyl)-2,3,4,5-tetr...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12 Show InChI InChI=1S/C19H20ClNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50004918 ((+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of the constrictor response to electrical stimulation in an isolated perfused rab...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50025695 (3-Allyl-1-(4-hydroxy-phenyl)-6-methyl-2,3,4,5-tetr...) Show SMILES Cc1c(O)c(O)cc2C(CN(CC=C)CCc12)c1ccc(O)cc1 Show InChI InChI=1S/C20H23NO3/c1-3-9-21-10-8-16-13(2)20(24)19(23)11-17(16)18(12-21)14-4-6-15(22)7-5-14/h3-7,11,18,22-24H,1,8-10,12H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50025696 (3-Allyl-6-bromo-1-(4-hydroxy-phenyl)-2,3,4,5-tetra...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12 Show InChI InChI=1S/C19H20BrNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine agonist (Dopamine receptor D1) activity was measured as increase in cAMP formation relative to maximum increase in dopamine-sensitive adenyl...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50225359 (CHEMBL284803) Show SMILES CCCN(CCC)CCc1cccc(NC(C)=O)c1 Show InChI InChI=1S/C16H26N2O/c1-4-10-18(11-5-2)12-9-15-7-6-8-16(13-15)17-14(3)19/h6-8,13H,4-5,9-12H2,1-3H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020686 (4-(2-Amino-ethyl)-7-hydroxy-1,3-dihydro-indol-2-on...) Show SMILES NCCc1ccc(O)c2NC(=O)Cc12 Show InChI InChI=1S/C10H12N2O2/c11-4-3-6-1-2-8(13)10-7(6)5-9(14)12-10/h1-2,13H,3-5,11H2,(H,12,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50019393 (4-(2-Dipropylamino-ethyl)-7-hydroxy-1,3-dihydro-in...) Show SMILES CCCN(CCC)CCc1ccc(O)c2NC(=O)Cc12 Show InChI InChI=1S/C16H24N2O2/c1-3-8-18(9-4-2)10-7-12-5-6-14(19)16-13(12)11-15(20)17-16/h5-6,19H,3-4,7-11H2,1-2H3,(H,17,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50025696 (3-Allyl-6-bromo-1-(4-hydroxy-phenyl)-2,3,4,5-tetra...) Show SMILES Oc1ccc(cc1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12 Show InChI InChI=1S/C19H20BrNO3/c1-2-8-21-9-7-14-15(10-17(23)19(24)18(14)20)16(11-21)12-3-5-13(22)6-4-12/h2-6,10,16,22-24H,1,7-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D2 agonist activity was determined for inhibition of the constrictor response to electrical stimulation in an isolated perfused rab...				J Med Chem 30: 35-40 (1987) BindingDB Entry DOI: 10.7270/Q2X92BV6
					More data for this Ligand-Target Pair