Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349916 (5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isopropylmorpho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349917 (5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isobutylmorphol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349917 (5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-isobutylmorphol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349919 ((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349919 ((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349920 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(methoxymethyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349920 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(methoxymethyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349921 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(ethoxymethyl)m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349921 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(ethoxymethyl)m...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349922 ((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349922 ((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349923 (2-((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349923 (2-((2R,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349924 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(2-methoxypropa...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349924 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(2-methoxypropa...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349925 ((R)-5-(2-(4-chlorobenzyl)-[1,4′-bipiperidin]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349925 ((R)-5-(2-(4-chlorobenzyl)-[1,4′-bipiperidin]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349926 (US10208020, Example 16 | US10538508, Example 16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349926 (US10208020, Example 16 | US10538508, Example 16 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349927 ((6R)-1′-(5-amino-4H-1,2,4-triazol-3-yl)-6-(4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349928 ((6R)-1′-(5-amino-4H-1,2,4-triazol-3-yl)-6-(4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349929 (5-((2S,4R)-2-(4-chlorobenzyl)-4-methoxy-[1,4′...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349930 (5-((2S,4S)-2-(4-chlorobenzyl)-4-methoxy-[1,4′...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM430048 ((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM430048 ((R)-5-(4-(2-(4-chlorobenzyl)pyrrolidin-1-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388665 (5-(4-((2S,5S)-2-(4-chlorobenzyl)-4,5-dimethylpiper...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388669 (5-(4-((2S,5S)-2,5-bis(4-chlorobenzyl)-4-methylpipe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388670 (5-(4-((2S,5S)-2-(4-chlorobenzyl)-5-(cyclohexylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388671 (5-(4-((2S,5S)-2-(4-chlorobenzyl)-5-isobutyl-4-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388678 (US10538508, Example 40 | US9944624, Ex. 40 | methy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388679 (2-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349956 (5-(4-((2S,4S)-2-(4-chlorobenzyl)-4-methoxypyrrolid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349956 (5-(4-((2S,4S)-2-(4-chlorobenzyl)-4-methoxypyrrolid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349957 ((3S,5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349957 ((3S,5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349958 ((5S)-1-(1-(5-amino-4H-1,2,4-triazol-3-yl)piperidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM388687 (5-(4-((3S,8aS)-3-(4-chlorobenzyl)hexahydropyrrolo[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349960 ((3R,5S)-1-(1-(5-amino-1H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349960 ((3R,5S)-1-(1-(5-amino-1H-1,2,4-triazol-3-yl)piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349961 (3-(4-((2S,4R)-2-(4-chlorobenzyl)-4-methoxypyrrolid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349961 (3-(4-((2S,4R)-2-(4-chlorobenzyl)-4-methoxypyrrolid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349965 ((S)-5-(4-(3-(4-chlorobenzyl)-6-methylene-1,4-oxaze...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349967 ((S)-5-(4-(3-(4-chlorobenzyl)-1-methyl-2,3-dihydro-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349968 ((S)-5-(4-(7-chloro-3-(4-chlorobenzyl)-1-methyl-2,3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349969 ((S)-5-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349970 ((S)-5-(4-(3-(4-chlorobenzyl)-7-fluoro-2,3-dihydrob...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349971 ((S)-5-(4-(7-chloro-3-(4-chlorobenzyl)-2,3-dihydrob...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349972 ((S)-5-(4-(7,9-dichloro-3-(4-chlorobenzyl)-2,3-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic mammalian chitinase (Homo sapiens (Human)) | BDBM349973 ((S)-5-(4-(3-(4-chlorobenzyl)-2,3-dihydropyrido[4,3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human AMCase was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). T... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM349920 (5-(4-((2R,5S)-5-(4-chlorobenzyl)-2-(methoxymethyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | Bioorg Med Chem Lett 19: 1164-7 (2009) BindingDB Entry DOI: 10.7270/Q22N54MD | |||||||||||
More data for this Ligand-Target Pair |
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