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Compile Data Set for Download or QSAR

Found 735 hits with Last Name = 'gomez' and Initial = 'r'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50479471
PNG
(CHEMBL491019 | MK-1107)
Show SMILES Clc1cc(Oc2cc(OCc3n[nH]c4ncccc34)ccc2Cl)cc(c1)C#N
Show InChI InChI=1S/C20H12Cl2N4O2/c21-13-6-12(10-23)7-15(8-13)28-19-9-14(3-4-17(19)22)27-11-18-16-2-1-5-24-20(16)26-25-18/h1-9H,11H2,(H,24,25,26)
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 0.220n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50479470
PNG
(CHEMBL489586 | MK-4965)
Show SMILES Nc1ccc2c(COc3ccc(Cl)c(Oc4cc(Cl)cc(c4)C#N)c3)n[nH]c2n1
Show InChI InChI=1S/C20H13Cl2N5O2/c21-12-5-11(9-23)6-14(7-12)29-18-8-13(1-3-16(18)22)28-10-17-15-2-4-19(24)25-20(15)27-26-17/h1-8H,10H2,(H3,24,25,26,27)
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 0.390n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50479470
PNG
(CHEMBL489586 | MK-4965)
Show SMILES Nc1ccc2c(COc3ccc(Cl)c(Oc4cc(Cl)cc(c4)C#N)c3)n[nH]c2n1
Show InChI InChI=1S/C20H13Cl2N5O2/c21-12-5-11(9-23)6-14(7-12)29-18-8-13(1-3-16(18)22)28-10-17-15-2-4-19(24)25-20(15)27-26-17/h1-8H,10H2,(H3,24,25,26,27)
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 0.390n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484635
PNG
(CHEMBL1939500)
Show SMILES Clc1cc(Oc2c(Cl)ccc3n(Cc4n[nH]c5ncccc45)nnc23)cc(c1)C#N
Show InChI InChI=1S/C20H11Cl2N7O/c21-12-6-11(9-23)7-13(8-12)30-19-15(22)3-4-17-18(19)26-28-29(17)10-16-14-2-1-5-24-20(14)27-25-16/h1-8H,10H2,(H,24,25,27)
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 0.430n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484496
PNG
(CHEMBL1928648)
Show SMILES Clc1cc(Oc2cc(Cc3n[nH]c4ncccc34)ccc2Cl)cc(c1)C#N
Show InChI InChI=1S/C20H12Cl2N4O/c21-14-6-13(11-23)7-15(10-14)27-19-9-12(3-4-17(19)22)8-18-16-2-1-5-24-20(16)26-25-18/h1-7,9-10H,8H2,(H,24,25,26)
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 0.480n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484632
PNG
(Mk-6186 | Mk6186)
Show SMILES Clc1cc(Oc2c(Cl)ccc3n(Cc4n[nH]c5ncccc45)ncc23)cc(c1)C#N
Show InChI InChI=1S/C21H12Cl2N6O/c22-13-6-12(9-24)7-14(8-13)30-20-16-10-26-29(19(16)4-3-17(20)23)11-18-15-2-1-5-25-21(15)28-27-18/h1-8,10H,11H2,(H,25,27,28)
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 0.580n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484629
PNG
(CHEMBL1939503)
Show SMILES Nc1ccc2c(Cn3nnc4c(Oc5cc(Cl)cc(c5)C#N)c(Cl)ccc34)n[nH]c2n1
Show InChI InChI=1S/C20H12Cl2N8O/c21-11-5-10(8-23)6-12(7-11)31-19-14(22)2-3-16-18(19)27-29-30(16)9-15-13-1-4-17(24)25-20(13)28-26-15/h1-7H,9H2,(H3,24,25,26,28)
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 0.940n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484495
PNG
(CHEMBL1928645)
Show SMILES Clc1cc(Oc2c(Cl)ccn(Cc3n[nH]c4ncccc34)c2=O)cc(c1)C#N
Show InChI InChI=1S/C19H11Cl2N5O2/c20-12-6-11(9-22)7-13(8-12)28-17-15(21)3-5-26(19(17)27)10-16-14-2-1-4-23-18(14)25-24-16/h1-8H,10H2,(H,23,24,25)
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 1.5n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484493
PNG
(CHEMBL1928646)
Show SMILES Clc1cc(Oc2c(Cl)c(Cl)cn(Cc3n[nH]c4ncccc34)c2=O)cc(c1)C#N
Show InChI InChI=1S/C19H10Cl3N5O2/c20-11-4-10(7-23)5-12(6-11)29-17-16(22)14(21)8-27(19(17)28)9-15-13-2-1-3-24-18(13)26-25-15/h1-6,8H,9H2,(H,24,25,26)
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 1.60n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484630
PNG
(CHEMBL1939502 | MK-7445)
Show SMILES Nc1ccc2c(Cn3ncc4c(Oc5cc(Cl)cc(c5)C#N)c(Cl)ccc34)n[nH]c2n1
Show InChI InChI=1S/C21H13Cl2N7O/c22-12-5-11(8-24)6-13(7-12)31-20-15-9-26-30(18(15)3-2-16(20)23)10-17-14-1-4-19(25)27-21(14)29-28-17/h1-7,9H,10H2,(H3,25,27,28,29)
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 1.70n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484494
PNG
(CHEMBL1928647)
Show SMILES Nc1ccc2c(Cn3ccc(Cl)c(Oc4cc(Cl)cc(c4)C#N)c3=O)n[nH]c2n1
Show InChI InChI=1S/C19H12Cl2N6O2/c20-11-5-10(8-22)6-12(7-11)29-17-14(21)3-4-27(19(17)28)9-15-13-1-2-16(23)24-18(13)26-25-15/h1-7H,9H2,(H3,23,24,25,26)
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 2.10n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484492
PNG
(CHEMBL1928643)
Show SMILES Cc1ccn(Cc2n[nH]c3ncccc23)c(=O)c1Oc1cc(Cl)cc(c1)C#N
Show InChI InChI=1S/C20H14ClN5O2/c1-12-4-6-26(11-17-16-3-2-5-23-19(16)25-24-17)20(27)18(12)28-15-8-13(10-22)7-14(21)9-15/h2-9H,11H2,1H3,(H,23,24,25)
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 3.70n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484624
PNG
(CHEMBL1939510)
Show SMILES Nc1cc(Cl)c(Oc2cc(Cl)cc(c2)C#N)cc1NCc1n[nH]c2ncccc12
Show InChI InChI=1S/C20H14Cl2N6O/c21-12-4-11(9-23)5-13(6-12)29-19-8-17(16(24)7-15(19)22)26-10-18-14-2-1-3-25-20(14)28-27-18/h1-8,26H,10,24H2,(H,25,27,28)
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 3.80n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484631
PNG
(CHEMBL1939501)
Show SMILES NCc1cc(Cl)cc(Oc2c(Cl)ccc3n(Cc4n[nH]c5ncccc45)nnc23)c1Cl
Show InChI InChI=1S/C20H14Cl3N7O/c21-11-6-10(8-24)17(23)16(7-11)31-19-13(22)3-4-15-18(19)27-29-30(15)9-14-12-2-1-5-25-20(12)28-26-14/h1-7H,8-9,24H2,(H,25,26,28)
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 4.30n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484634
PNG
(CHEMBL1939504)
Show SMILES Clc1cc(Oc2c(Cl)ccc3n(Cc4n[nH]c5ncccc45)cnc23)cc(c1)C#N
Show InChI InChI=1S/C21H12Cl2N6O/c22-13-6-12(9-24)7-14(8-13)30-20-16(23)3-4-18-19(20)26-11-29(18)10-17-15-2-1-5-25-21(15)28-27-17/h1-8,11H,10H2,(H,25,27,28)
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 5.30n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484633
PNG
(CHEMBL1939507)
Show SMILES Clc1nn(Cc2n[nH]c3ncccc23)c2ccc(Cl)c(Oc3cc(Cl)cc(c3)C#N)c12
Show InChI InChI=1S/C21H11Cl3N6O/c22-12-6-11(9-25)7-13(8-12)31-19-15(23)3-4-17-18(19)20(24)29-30(17)10-16-14-2-1-5-26-21(14)28-27-16/h1-8H,10H2,(H,26,27,28)
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 28n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484497
PNG
(CHEMBL1928644)
Show SMILES Cc1ccn(CCc2n[nH]c3ncccc23)c(=O)c1Oc1cc(Cl)cc(c1)C#N
Show InChI InChI=1S/C21H16ClN5O2/c1-13-4-7-27(8-5-18-17-3-2-6-24-20(17)26-25-18)21(28)19(13)29-16-10-14(12-23)9-15(22)11-16/h2-4,6-7,9-11H,5,8H2,1H3,(H,24,25,26)
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 58n/an/an/an/an/an/an/an/a



Merck Research Labs.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

Bioorg Med Chem Lett 21: 7344-50 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.027
BindingDB Entry DOI: 10.7270/Q25Q4ZZ2
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484625
PNG
(CHEMBL1939509)
Show SMILES Clc1cc(Oc2cc3n(Cc4n[nH]c5ncccc45)cnc3cc2Cl)cc(c1)C#N
Show InChI InChI=1S/C21H12Cl2N6O/c22-13-4-12(9-24)5-14(6-13)30-20-8-19-17(7-16(20)23)26-11-29(19)10-18-15-2-1-3-25-21(15)28-27-18/h1-8,11H,10H2,(H,25,27,28)
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>100n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484626
PNG
(CHEMBL1939508)
Show SMILES Clc1cc(Oc2cc3n(Cc4n[nH]c5ncccc45)nnc3cc2Cl)cc(c1)C#N
Show InChI InChI=1S/C20H11Cl2N7O/c21-12-4-11(9-23)5-13(6-12)30-19-8-18-16(7-15(19)22)26-28-29(18)10-17-14-2-1-3-24-20(14)27-25-17/h1-8H,10H2,(H,24,25,27)
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>300n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484628
PNG
(CHEMBL1939505)
Show SMILES Clc1cc(Oc2c(Cl)ccc3n(Cc4n[nH]c5ncccc45)c(=O)[nH]c23)cc(c1)C#N
Show InChI InChI=1S/C21H12Cl2N6O2/c22-12-6-11(9-24)7-13(8-12)31-19-15(23)3-4-17-18(19)26-21(30)29(17)10-16-14-2-1-5-25-20(14)28-27-16/h1-8H,10H2,(H,26,30)(H,25,27,28)
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>600n/an/an/an/an/an/an/an/a



Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50484627
PNG
(CHEMBL1939506)
Show SMILES Cc1nc2c(Oc3cc(Cl)cc(c3)C#N)c(Cl)ccc2n1Cc1n[nH]c2ncccc12
Show InChI InChI=1S/C22H14Cl2N6O/c1-12-27-20-19(30(12)11-18-16-3-2-6-26-22(16)29-28-18)5-4-17(24)21(20)31-15-8-13(10-25)7-14(23)9-15/h2-9H,11H2,1H3,(H,26,28,29)
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Merck Co.

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay

J Med Chem 54: 7920-33 (2011)


Article DOI: 10.1021/jm2010173
BindingDB Entry DOI: 10.7270/Q2W66PMC
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079961
PNG
((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-2-ylmet...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc2ccccc2c1
Show InChI InChI=1S/C40H47N5O4S/c1-4-28(2)37(43-38(46)21-34-22-41-27-45(34)23-29-16-17-30-10-5-6-12-32(30)20-29)25-44(26-39(47)42-36(40(48)49)18-19-50-3)24-33-14-9-13-31-11-7-8-15-35(31)33/h5-17,20,22,27-28,36-37H,4,18-19,21,23-26H2,1-3H3,(H,42,47)(H,43,46)(H,48,49)/t28?,36-,37+/m0/s1
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n/an/a 0.120n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079974
PNG
((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-1-ylmet...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1cccc2ccccc12
Show InChI InChI=1S/C40H47N5O4S/c1-4-28(2)37(43-38(46)21-33-22-41-27-45(33)24-32-16-10-14-30-12-6-8-18-35(30)32)25-44(26-39(47)42-36(40(48)49)19-20-50-3)23-31-15-9-13-29-11-5-7-17-34(29)31/h5-18,22,27-28,36-37H,4,19-21,23-26H2,1-3H3,(H,42,47)(H,43,46)(H,48,49)/t28?,36-,37+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079956
PNG
((S)-2-[2-({(S)-2-[2-(3-Benzyl-3H-imidazol-4-yl)-ac...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccccc1
Show InChI InChI=1S/C36H45N5O4S/c1-4-26(2)33(39-34(42)19-30-20-37-25-41(30)21-27-11-6-5-7-12-27)23-40(24-35(43)38-32(36(44)45)17-18-46-3)22-29-15-10-14-28-13-8-9-16-31(28)29/h5-16,20,25-26,32-33H,4,17-19,21-24H2,1-3H3,(H,38,43)(H,39,42)(H,44,45)/t26?,32-,33+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50369443
PNG
(CHEMBL252953)
Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc(cc1)C#N
Show InChI InChI=1S/C37H44N6O4S/c1-4-26(2)34(41-35(44)18-31-20-39-25-43(31)21-28-14-12-27(19-38)13-15-28)23-42(24-36(45)40-33(37(46)47)16-17-48-3)22-30-10-7-9-29-8-5-6-11-32(29)30/h5-15,20,25-26,33-34H,4,16-18,21-24H2,1-3H3,(H,40,45)(H,41,44)(H,46,47)/t26-,33+,34-/m1/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079966
PNG
((S)-2-{2-[((S)-3-Methyl-2-{2-[3-(4-nitro-benzyl)-3...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C36H44N6O6S/c1-4-25(2)33(39-34(43)18-30-19-37-24-41(30)20-26-12-14-29(15-13-26)42(47)48)22-40(23-35(44)38-32(36(45)46)16-17-49-3)21-28-10-7-9-27-8-5-6-11-31(27)28/h5-15,19,24-25,32-33H,4,16-18,20-23H2,1-3H3,(H,38,44)(H,39,43)(H,45,46)/t25?,32-,33+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079978
PNG
((S)-2-{2-[((S)-2-{2-[3-((E)-3,7-Dimethyl-octa-2,6-...)
Show SMILES [#6]-[#6]-[#6](-[#6])-[#6@@H](-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#16]-[#6])-[#6](-[#8])=O)-[#6]-c1cccc2ccccc12)-[#7]-[#6](=O)-[#6]-c1cncn1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]
Show InChI InChI=1S/C39H55N5O4S/c1-7-30(5)36(42-37(45)22-33-23-40-27-44(33)20-18-29(4)13-10-12-28(2)3)25-43(26-38(46)41-35(39(47)48)19-21-49-6)24-32-16-11-15-31-14-8-9-17-34(31)32/h8-9,11-12,14-18,23,27,30,35-36H,7,10,13,19-22,24-26H2,1-6H3,(H,41,46)(H,42,45)(H,47,48)/b29-18+/t30?,35-,36+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079971
PNG
((S)-2-{2-[((S)-2-{2-[3-(4-Fluoro-benzyl)-3H-imidaz...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc(F)cc1
Show InChI InChI=1S/C36H44FN5O4S/c1-4-25(2)33(40-34(43)18-30-19-38-24-42(30)20-26-12-14-29(37)15-13-26)22-41(23-35(44)39-32(36(45)46)16-17-47-3)21-28-10-7-9-27-8-5-6-11-31(27)28/h5-15,19,24-25,32-33H,4,16-18,20-23H2,1-3H3,(H,39,44)(H,40,43)(H,45,46)/t25?,32-,33+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079968
PNG
((S)-2-{2-[((S)-2-{2-[3-(4-Methoxy-benzyl)-3H-imida...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc(OC)cc1
Show InChI InChI=1S/C37H47N5O5S/c1-5-26(2)34(40-35(43)19-30-20-38-25-42(30)21-27-13-15-31(47-3)16-14-27)23-41(24-36(44)39-33(37(45)46)17-18-48-4)22-29-11-8-10-28-9-6-7-12-32(28)29/h6-16,20,25-26,33-34H,5,17-19,21-24H2,1-4H3,(H,39,44)(H,40,43)(H,45,46)/t26?,33-,34+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079962
PNG
((S)-2-[2-({(S)-3-Methyl-2-[2-(3-pyridin-4-ylmethyl...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccncc1
Show InChI InChI=1S/C35H44N6O4S/c1-4-25(2)32(39-33(42)18-29-19-37-24-41(29)20-26-12-15-36-16-13-26)22-40(23-34(43)38-31(35(44)45)14-17-46-3)21-28-10-7-9-27-8-5-6-11-30(27)28/h5-13,15-16,19,24-25,31-32H,4,14,17-18,20-23H2,1-3H3,(H,38,43)(H,39,42)(H,44,45)/t25?,31-,32+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079963
PNG
((S)-4-Methylsulfanyl-2-{2-[((S)-3-methyl-2-{2-[3-(...)
Show SMILES [#6]-[#6]-[#6](-[#6])-[#6@@H](-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#16]-[#6])-[#6](-[#8])=O)-[#6]-c1cccc2ccccc12)-[#7]-[#6](=O)-[#6]-c1cncn1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]
Show InChI InChI=1S/C45H65N5O4S/c1-8-36(6)42(48-43(51)27-39-28-46-32-50(39)25-23-35(5)17-10-9-16-34(4)18-13-15-33(2)3)30-49(31-44(52)47-41(45(53)54)24-26-55-7)29-38-21-14-20-37-19-11-12-22-40(37)38/h11-12,14-16,19-23,28,32,36,41-42H,8-10,13,17-18,24-27,29-31H2,1-7H3,(H,47,52)(H,48,51)(H,53,54)/b34-16+,35-23+/t36?,41-,42+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560274
PNG
(US11377439, Example 111)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NC1CCC1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))		BDBM50497566
PNG
(CHEMBL3344193)
Show SMILES COc1cc(CNCc2ccncc2)ccc1OCc1ccc(Cl)cc1
Show InChI InChI=1S/C21H21ClN2O2/c1-25-21-12-18(14-24-13-16-8-10-23-11-9-16)4-7-20(21)26-15-17-2-5-19(22)6-3-17/h2-12,24H,13-15H2,1H3
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Johann-Wolfgang-Goethe University of Frankfurt

Curated by ChEMBL


Assay Description
Inhibition of Plk1 immunoprecipitated from human HeLa cells using casein substrate after 12 to 26 hrs by autoradiography

Bioorg Med Chem Lett 24: 5063-9 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.015
BindingDB Entry DOI: 10.7270/Q26Q2171
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560275
PNG
(US11377439, Example 112)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NCC(F)(F)F)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50079964
PNG
((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...)
Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc2ccccc2n1
Show InChI InChI=1S/C39H46N6O4S/c1-4-27(2)36(43-37(46)20-32-21-40-26-45(32)23-31-17-16-29-11-6-8-15-34(29)41-31)24-44(25-38(47)42-35(39(48)49)18-19-50-3)22-30-13-9-12-28-10-5-7-14-33(28)30/h5-17,21,26-27,35-36H,4,18-20,22-25H2,1-3H3,(H,42,47)(H,43,46)(H,48,49)/t27?,35-,36+/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by Farnesyltransferase

J Med Chem 42: 3356-68 (1999)


Article DOI: 10.1021/jm990080l
BindingDB Entry DOI: 10.7270/Q27P9020
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560277
PNG
(US11377439, Example 114)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)N1CC(F)(F)C1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560273
PNG
(US11377439, Example 110)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NCC1CC1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560270
PNG
(US11377439, Example 107)
Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(=O)N[C@H](CC1CCCCC1)C(=O)N1C[C@H](C[C@H]1C(=O)NC1(CCSCC1)C(=O)C(N)=O)n1nncc1C(C)(C)O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560266
PNG
(US11377439, Example 103)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)C(=O)N1CCCC1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560279
PNG
(US11377439, Example 116)
Show SMILES CC(C)(C)C(=O)CNS(=O)(=O)c1ccc(cc1)C(=O)N[C@H](CC1CCCCC1)C(=O)N1C[C@H](C[C@H]1C(=O)NC1(CCSCC1)C(=O)C(N)=O)n1nncc1C(C)(C)O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560251
PNG
(US11377439, Example 88)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2[nH]nnc2c1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560256
PNG
(US11377439, Example 93)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NC1CC(F)(F)C1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560238
PNG
(US11377439, Example 75)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)C(=O)NC1(CCSCC1)C(=O)C(N)=O
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560276
PNG
(US11377439, Example 113)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NC1CCSCC1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560299
PNG
(US11377439, Example 136)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NC1CC2(CCC2)C1)C(=O)NC1(CCS(=O)(=O)CC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50240279
PNG
(CHEMBL4080553)
Show SMILES Fc1cnc(NS(=O)(=O)c2cc(Cl)c(NCC34CCCN3CCC4)cc2F)s1
Show InChI InChI=1S/C17H19ClF2N4O2S2/c18-11-7-14(28(25,26)23-16-21-9-15(20)27-16)12(19)8-13(11)22-10-17-3-1-5-24(17)6-2-4-17/h7-9,22H,1-6,10H2,(H,21,23)
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Department of Discovery Chemistry Merck& Co.

Curated by ChEMBL


Assay Description
Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...

Bioorg Med Chem Lett 27: 2087-2093 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.085
BindingDB Entry DOI: 10.7270/Q29025XB
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560137
PNG
(US11377439, Example 15)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2cc(OC(F)(F)F)ccc2c1)C(=O)NC1(CCOCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560246
PNG
(US11377439, Example 83)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(cc1)S(=O)(=O)NC1CC1)C(=O)NC1(CCSCC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560281
PNG
(US11377439, Example 118)
Show SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)C(=O)NC1(CCS(=O)(=O)CC1)C(=O)C(N)=O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
Serine protease HTRA1


(Homo sapiens (Human))		BDBM560262
PNG
(US11377439, Example 99)
Show SMILES CC(C)S(=O)(=O)c1ccc(cc1)C(=O)N[C@H](CC1CCCCC1)C(=O)N1C[C@H](C[C@H]1C(=O)NC1(CCSCC1)C(=O)C(N)=O)n1nncc1C(C)(C)O |r|
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TBA

Assay Description
Serial dilutions (1/3) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of soluti...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z03CDC
More data for this
Ligand-Target Pair
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