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Compile Data Set for Download or QSAR

Found 87 hits with Last Name = 'gottschlich' and Initial = 'r'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366263
PNG
(CHEMBL45535)
Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(OC(F)(F)F)cc2)CC1)c1ccc2OCOc2c1
Show InChI InChI=1S/C23H23F3N2O6/c24-23(25,26)34-17-4-2-16(3-5-17)28-13-18(33-21(28)29)12-27-9-7-22(30,8-10-27)15-1-6-19-20(11-15)32-14-31-19/h1-6,11,18,30H,7-10,12-14H2/t18-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366358
PNG
(CHEMBL559010 | EMD-60400)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)Cc1ccccc1N |r|
Show InChI InChI=1S/C21H27N3O2/c1-23(21(26)13-17-9-5-6-10-19(17)22)20(16-7-3-2-4-8-16)15-24-12-11-18(25)14-24/h2-10,18,20,25H,11-15,22H2,1H3/t18-,20+/m0/s1
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1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50000780
PNG
(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m0/s1
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1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366262
PNG
(CHEMBL417353)
Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(OCC3CC3)cc2)CC1)c1ccc2OCOc2c1
Show InChI InChI=1S/C26H30N2O6/c29-25-28(20-4-6-21(7-5-20)31-16-18-1-2-18)15-22(34-25)14-27-11-9-26(30,10-12-27)19-3-8-23-24(13-19)33-17-32-23/h3-8,13,18,22,30H,1-2,9-12,14-17H2/t22-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366356
PNG
(ASIMADOLINE HYDROCHLORIDE | EMD-61753)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H30N2O2/c1-28(25(21-11-5-2-6-12-21)20-29-18-17-24(30)19-29)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,24-26,30H,17-20H2,1H3/t24-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366350
PNG
(CHEMBL555800)
Show SMILES CC(C)C(C(=O)N(C)[C@H](CN1CC[C@H](O)C1)c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C24H32N2O2/c1-18(2)23(20-12-8-5-9-13-20)24(28)25(3)22(19-10-6-4-7-11-19)17-26-15-14-21(27)16-26/h4-13,18,21-23,27H,14-17H2,1-3H3/t21-,22+,23?/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366274
PNG
(CHEMBL47715)
Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(Cl)cc2)CC1)c1ccc2OCOc2c1
Show InChI InChI=1S/C22H23ClN2O5/c23-16-2-4-17(5-3-16)25-13-18(30-21(25)26)12-24-9-7-22(27,8-10-24)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,27H,7-10,12-14H2/t18-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366350
PNG
(CHEMBL555800)
Show SMILES CC(C)C(C(=O)N(C)[C@H](CN1CC[C@H](O)C1)c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C24H32N2O2/c1-18(2)23(20-12-8-5-9-13-20)24(28)25(3)22(19-10-6-4-7-11-19)17-26-15-14-21(27)16-26/h4-13,18,21-23,27H,14-17H2,1-3H3/t21-,22+,23?/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366349
PNG
(CHEMBL543707)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1cccs1)c1cccs1 |r|
Show InChI InChI=1S/C23H26N2O2S2/c1-24(23(27)22(20-9-5-13-28-20)21-10-6-14-29-21)19(17-7-3-2-4-8-17)16-25-12-11-18(26)15-25/h2-10,13-14,18-19,22,26H,11-12,15-16H2,1H3/t18-,19+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366361
PNG
(CHEMBL538802)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2Oc2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O3/c1-28(23(19-9-3-2-4-10-19)18-29-16-15-20(30)17-29)27(31)26-21-11-5-7-13-24(21)32-25-14-8-6-12-22(25)26/h2-14,20,23,26,30H,15-18H2,1H3/t20-,23+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366363
PNG
(CHEMBL543236)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2Cc2ccccc12 |r|
Show InChI InChI=1S/C28H30N2O2/c1-29(26(20-9-3-2-4-10-20)19-30-16-15-23(31)18-30)28(32)27-24-13-7-5-11-21(24)17-22-12-6-8-14-25(22)27/h2-14,23,26-27,31H,15-19H2,1H3/t23-,26+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366265
PNG
(CHEMBL47774)
Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccccc2)CC1)c1ccc2OCOc2c1
Show InChI InChI=1S/C22H24N2O5/c25-21-24(17-4-2-1-3-5-17)14-18(29-21)13-23-10-8-22(26,9-11-23)16-6-7-19-20(12-16)28-15-27-19/h1-7,12,18,26H,8-11,13-15H2/t18-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366355
PNG
(CHEMBL543476)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C27H28Cl2N2O2/c1-30(25(19-5-3-2-4-6-19)18-31-16-15-24(32)17-31)27(33)26(20-7-11-22(28)12-8-20)21-9-13-23(29)14-10-21/h2-14,24-26,32H,15-18H2,1H3/t24-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366362
PNG
(CHEMBL540345)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1cccc(NC(C)=O)c1)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H33N3O3/c1-21(33)30-25-15-9-14-24(18-25)27(20-32-17-16-26(34)19-32)31(2)29(35)28(22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-15,18,26-28,34H,16-17,19-20H2,1-2H3,(H,30,33)/t26-,27+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366364
PNG
(CHEMBL543947)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2-c2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O2/c1-28(25(19-9-3-2-4-10-19)18-29-16-15-20(30)17-29)27(31)26-23-13-7-5-11-21(23)22-12-6-8-14-24(22)26/h2-14,20,25-26,30H,15-18H2,1H3/t20-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366360
PNG
(CHEMBL538063)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1cccc(N)c1)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H31N3O2/c1-29(25(19-30-16-15-24(31)18-30)22-13-8-14-23(28)17-22)27(32)26(20-9-4-2-5-10-20)21-11-6-3-7-12-21/h2-14,17,24-26,31H,15-16,18-19,28H2,1H3/t24-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366359
PNG
(CHEMBL543948)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccc(O)cc1)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H30N2O3/c1-28(25(19-29-17-16-24(31)18-29)20-12-14-23(30)15-13-20)27(32)26(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,24-26,30-31H,16-19H2,1H3/t24-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366357
PNG
(CHEMBL542036)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccc(F)cc1)c1ccc(F)cc1 |r|
Show InChI InChI=1S/C27H28F2N2O2/c1-30(25(19-5-3-2-4-6-19)18-31-16-15-24(32)17-31)27(33)26(20-7-11-22(28)12-8-20)21-9-13-23(29)14-10-21/h2-14,24-26,32H,15-18H2,1H3/t24-,25+/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366273
PNG
(CHEMBL417357)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccccc2)OC1=O
Show InChI InChI=1S/C22H26N2O4/c1-27-19-9-7-18(8-10-19)24-16-20(28-21(24)25)15-23-13-11-22(26,12-14-23)17-5-3-2-4-6-17/h2-10,20,26H,11-16H2,1H3/t20-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366365
PNG
(CHEMBL540335)
Show SMILES COc1ccc(cc1)[C@@H](CN1CC[C@H](O)C1)N(C)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H32N2O3/c1-29(28(32)27(22-9-5-3-6-10-22)23-11-7-4-8-12-23)26(20-30-18-17-24(31)19-30)21-13-15-25(33-2)16-14-21/h3-16,24,26-27,31H,17-20H2,1-2H3/t24-,26+/m0/s1
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7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366351
PNG
(CHEMBL545346)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(C1CCCCC1)c1ccccc1 |r|
Show InChI InChI=1S/C27H36N2O2/c1-28(25(21-11-5-2-6-12-21)20-29-18-17-24(30)19-29)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-3,5-8,11-14,23-26,30H,4,9-10,15-20H2,1H3/t24-,25+,26?/m0/s1
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366351
PNG
(CHEMBL545346)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(C1CCCCC1)c1ccccc1 |r|
Show InChI InChI=1S/C27H36N2O2/c1-28(25(21-11-5-2-6-12-21)20-29-18-17-24(30)19-29)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-3,5-8,11-14,23-26,30H,4,9-10,15-20H2,1H3/t24-,25+,26?/m0/s1
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366352
PNG
(CHEMBL553085)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2Sc2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O2S/c1-28(23(19-9-3-2-4-10-19)18-29-16-15-20(30)17-29)27(31)26-21-11-5-7-13-24(21)32-25-14-8-6-12-22(25)26/h2-14,20,23,26,30H,15-18H2,1H3/t20-,23+/m0/s1
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366269
PNG
(CHEMBL47714)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(OC)cc2)OC1=O
Show InChI InChI=1S/C23H28N2O5/c1-28-19-7-3-17(4-8-19)23(27)11-13-24(14-12-23)15-21-16-25(22(26)30-21)18-5-9-20(29-2)10-6-18/h3-10,21,27H,11-16H2,1-2H3/t21-/m0/s1
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12n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366258
PNG
(CHEMBL44604)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(F)cc2)OC1=O
Show InChI InChI=1S/C22H25FN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m0/s1
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14n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366253
PNG
(CHEMBL50771)
Show SMILES CCOc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O
Show InChI InChI=1S/C24H28N2O6/c1-2-29-19-6-4-18(5-7-19)26-15-20(32-23(26)27)14-25-11-9-24(28,10-12-25)17-3-8-21-22(13-17)31-16-30-21/h3-8,13,20,28H,2,9-12,14-16H2,1H3/t20-/m0/s1
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366275
PNG
(CHEMBL417181)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(Cl)c(c2)C(F)(F)F)OC1=O
Show InChI InChI=1S/C23H24ClF3N2O4/c1-32-17-5-3-16(4-6-17)29-14-18(33-21(29)30)13-28-10-8-22(31,9-11-28)15-2-7-20(24)19(12-15)23(25,26)27/h2-7,12,18,31H,8-11,13-14H2,1H3/t18-/m0/s1
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366254
PNG
(CHEMBL296504)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC(C)(C)Oc3c2)OC1=O
Show InChI InChI=1S/C25H30N2O6/c1-24(2)32-21-9-4-17(14-22(21)33-24)25(29)10-12-26(13-11-25)15-20-16-27(23(28)31-20)18-5-7-19(30-3)8-6-18/h4-9,14,20,29H,10-13,15-16H2,1-3H3/t20-/m0/s1
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16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366277
PNG
(CHEMBL48075)
Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(F)cc2)CC1)c1ccc2OCOc2c1
Show InChI InChI=1S/C22H23FN2O5/c23-16-2-4-17(5-3-16)25-13-18(30-21(25)26)12-24-9-7-22(27,8-10-24)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,27H,7-10,12-14H2/t18-/m0/s1
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16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366260
PNG
(CHEMBL295891)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCCc3c2)OC1=O
Show InChI InChI=1S/C24H28N2O5/c1-29-20-5-3-19(4-6-20)26-16-21(31-23(26)27)15-25-11-9-24(28,10-12-25)18-2-7-22-17(14-18)8-13-30-22/h2-7,14,21,28H,8-13,15-16H2,1H3/t21-/m0/s1
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17n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366251
PNG
(CHEMBL46438)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(OC)c(OC)c2)OC1=O
Show InChI InChI=1S/C24H30N2O6/c1-29-19-7-5-18(6-8-19)26-16-20(32-23(26)27)15-25-12-10-24(28,11-13-25)17-4-9-21(30-2)22(14-17)31-3/h4-9,14,20,28H,10-13,15-16H2,1-3H3/t20-/m0/s1
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18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366257
PNG
(CHEMBL48124)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(CC2)c2ccc3OCOc3c2)OC1=O
Show InChI InChI=1S/C23H26N2O5/c1-27-19-5-3-18(4-6-19)25-14-20(30-23(25)26)13-24-10-8-16(9-11-24)17-2-7-21-22(12-17)29-15-28-21/h2-7,12,16,20H,8-11,13-15H2,1H3/t20-/m0/s1
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19n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366267
PNG
(CHEMBL45686 | Panamesine)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O
Show InChI InChI=1S/C23H26N2O6/c1-28-18-5-3-17(4-6-18)25-14-19(31-22(25)26)13-24-10-8-23(27,9-11-24)16-2-7-20-21(12-16)30-15-29-20/h2-7,12,19,27H,8-11,13-15H2,1H3/t19-/m0/s1
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19n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366268
PNG
(CHEMBL298492)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(C)cc2)OC1=O
Show InChI InChI=1S/C23H28N2O4/c1-17-3-5-18(6-4-17)23(27)11-13-24(14-12-23)15-21-16-25(22(26)29-21)19-7-9-20(28-2)10-8-19/h3-10,21,27H,11-16H2,1-2H3/t21-/m0/s1
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19n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366353
PNG
(CHEMBL552587)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2CCc2ccccc12 |r|
Show InChI InChI=1S/C29H32N2O2/c1-30(27(23-11-3-2-4-12-23)20-31-18-17-24(32)19-31)29(33)28-25-13-7-5-9-21(25)15-16-22-10-6-8-14-26(22)28/h2-14,24,27-28,32H,15-20H2,1H3/t24-,27+/m0/s1
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20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366366
PNG
(CHEMBL539317)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1cccc(c1)[N+]([O-])=O)C(=O)C(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H29N3O4/c1-28(27(32)26(20-9-4-2-5-10-20)21-11-6-3-7-12-21)25(19-29-16-15-24(31)18-29)22-13-8-14-23(17-22)30(33)34/h2-14,17,24-26,31H,15-16,18-19H2,1H3/t24-,25+/m0/s1
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20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50366354
PNG
(CHEMBL553084)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccc(C)cc1)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C29H34N2O2/c1-21-9-13-24(14-10-21)28(25-15-11-22(2)12-16-25)29(33)30(3)27(23-7-5-4-6-8-23)20-31-18-17-26(32)19-31/h4-16,26-28,32H,17-20H2,1-3H3/t26-,27+/m0/s1
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20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366276
PNG
(CHEMBL45849)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(Cl)cc2)OC1=O
Show InChI InChI=1S/C22H25ClN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m0/s1
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21n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366271
PNG
(CHEMBL45968)
Show SMILES Oc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O
Show InChI InChI=1S/C22H24N2O6/c25-17-4-2-16(3-5-17)24-13-18(30-21(24)26)12-23-9-7-22(27,8-10-23)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,25,27H,7-10,12-14H2/t18-/m0/s1
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24n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366261
PNG
(CHEMBL47678)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCCOc3c2)OC1=O
Show InChI InChI=1S/C24H28N2O6/c1-29-19-5-3-18(4-6-19)26-16-20(32-23(26)27)15-25-10-8-24(28,9-11-25)17-2-7-21-22(14-17)31-13-12-30-21/h2-7,14,20,28H,8-13,15-16H2,1H3/t20-/m0/s1
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31n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366255
PNG
(CHEMBL45962)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccsc2)OC1=O
Show InChI InChI=1S/C20H24N2O4S/c1-25-17-4-2-16(3-5-17)22-13-18(26-19(22)23)12-21-9-7-20(24,8-10-21)15-6-11-27-14-15/h2-6,11,14,18,24H,7-10,12-13H2,1H3/t18-/m0/s1
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34n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366256
PNG
(CHEMBL297634)
Show SMILES COc1ccc(cc1)N1C[C@@H](CN2CCC(O)(CC2)c2ccccc2)OC1=O
Show InChI InChI=1S/C22H26N2O4/c1-27-19-9-7-18(8-10-19)24-16-20(28-21(24)25)15-23-13-11-22(26,12-14-23)17-5-3-2-4-6-17/h2-10,20,26H,11-16H2,1H3/t20-/m1/s1
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34n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50366364
PNG
(CHEMBL543947)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2-c2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O2/c1-28(25(19-9-3-2-4-10-19)18-29-16-15-20(30)17-29)27(31)26-23-13-7-5-11-21(23)22-12-6-8-14-24(22)26/h2-14,20,25-26,30H,15-18H2,1H3/t20-,25+/m0/s1
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40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity to mu opioid receptor determined in the presence of [3H]- PL 017 using membranes prepared from rat cerebrum


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366264
PNG
(CHEMBL295039)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2cccs2)OC1=O
Show InChI InChI=1S/C20H24N2O4S/c1-25-16-6-4-15(5-7-16)22-14-17(26-19(22)23)13-21-10-8-20(24,9-11-21)18-3-2-12-27-18/h2-7,12,17,24H,8-11,13-14H2,1H3/t17-/m0/s1
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41n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50026045
PNG
((R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
Show InChI InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1
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55n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50366364
PNG
(CHEMBL543947)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1c2ccccc2-c2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O2/c1-28(25(19-9-3-2-4-10-19)18-29-16-15-20(30)17-29)27(31)26-23-13-7-5-11-21(23)22-12-6-8-14-24(22)26/h2-14,20,25-26,30H,15-18H2,1H3/t20-,25+/m0/s1
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60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity to delta opioid receptor determined in the presence of [3H]- [D-Pen2,5]enkephalin using membranes prepared from rat cerebrum


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50366270
PNG
(CHEMBL47279)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC4(CCCC4)Oc3c2)OC1=O
Show InChI InChI=1S/C27H32N2O6/c1-32-21-7-5-20(6-8-21)29-18-22(33-25(29)30)17-28-14-12-26(31,13-15-28)19-4-9-23-24(16-19)35-27(34-23)10-2-3-11-27/h4-9,16,22,31H,2-3,10-15,17-18H2,1H3/t22-/m0/s1
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62n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50002238
PNG
((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...)
Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1
Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2
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71n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047


Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50366350
PNG
(CHEMBL555800)
Show SMILES CC(C)C(C(=O)N(C)[C@H](CN1CC[C@H](O)C1)c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C24H32N2O2/c1-18(2)23(20-12-8-5-9-13-20)24(28)25(3)22(19-10-6-4-7-11-19)17-26-15-14-21(27)16-26/h4-13,18,21-23,27H,14-17H2,1-3H3/t21-,22+,23?/m0/s1
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>100n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity to delta opioid receptor determined in the presence of [3H]- [D-Pen2,5]enkephalin using membranes prepared from rat cerebrum


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50366351
PNG
(CHEMBL545346)
Show SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(C1CCCCC1)c1ccccc1 |r|
Show InChI InChI=1S/C27H36N2O2/c1-28(25(21-11-5-2-6-12-21)20-29-18-17-24(30)19-29)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-3,5-8,11-14,23-26,30H,4,9-10,15-20H2,1H3/t24-,25+,26?/m0/s1
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>100n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity to mu opioid receptor determined in the presence of [3H]- PL 017 using membranes prepared from rat cerebrum


Bioorg Med Chem Lett 4: 677-682 (1994)


Article DOI: 10.1016/S0960-894X(01)80179-7
BindingDB Entry DOI: 10.7270/Q28C9WRX
More data for this
Ligand-Target Pair
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