Compile Data Set for Download or QSAR

Found 964 hits with Last Name = 'hahn' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642921 (US20240000767, Example 100 | US20240000767, Exampl...) Show SMILES COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642917 (N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3-met...) Show SMILES C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280009 (CHEMBL88059 | N-((S)-1,2,3-Trimethoxy-10-methylami...) Show SMILES CNc1ccc2-c3c(CC[C@H](NC(C)=O)c2cc1=O)cc(OC)c(OC)c3OC Show InChI InChI=1S/C22H26N2O5/c1-12(25)24-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-17(23-2)18(26)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,26)(H,24,25)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280008 (2-Methylamino-5-(2,3,4-trimethoxy-phenyl)-cyclohep...) Show SMILES CNc1ccc(ccc1=O)-c1ccc(OC)c(OC)c1OC Show InChI InChI=1S/C17H19NO4/c1-18-13-8-5-11(6-9-14(13)19)12-7-10-15(20-2)17(22-4)16(12)21-3/h5-10H,1-4H3,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50279934 (2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...) Show SMILES COc1ccc(c(OC)c1OC)-c1ccc(OC)c(=O)cc1 Show InChI InChI=1S/C17H18O5/c1-19-14-9-6-11(5-8-13(14)18)12-7-10-15(20-2)17(22-4)16(12)21-3/h5-10H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280007 (2-Methylsulfanyl-5-(2,3,4-trimethoxy-phenyl)-cyclo...) Show SMILES COc1ccc(c(OC)c1OC)-c1ccc(SC)c(=O)cc1 Show InChI InChI=1S/C17H18O4S/c1-19-14-9-7-12(16(20-2)17(14)21-3)11-5-8-13(18)15(22-4)10-6-11/h5-10H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574215 (CHEMBL4878875 | US20240000767, Example 102) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574218 (CHEMBL4875484 | US20240000767, Example 135) Show SMILES FC1CN(CCC1N1CCCC2(CC2)C1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574219 (CHEMBL4852159 | US20240000767, Example 140) Show SMILES COc1cccc2CCN(Cc12)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574216 (CHEMBL4876214 | US20240000767, Example 108) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2(F)F)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574220 (CHEMBL4868807 | US20240000767, Example 143) Show SMILES Cc1ccc2CCN(Cc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643032 (US20240000767, Example 111 | diamix-N-[(3,5-Difluo...) Show SMILES C[C@@H]1CCCN(C1)C1CCN(CC1F)c1nc(cs1)C(=O)NCc1ncc(F)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574217 (CHEMBL4866383 | US20240000767, Example 126) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642981 (US20240000767, Example 106 | US20240000767, Exampl...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC(F)(F)F)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643051 (N-[(3,5-Difluoropyridin-2-yl)methyl]-4-ethyl-2-[(3...) Show SMILES CCc1nc(sc1C(=O)NCc1ncc(F)cc1F)N1CCC(CC1)N1CCC[C@@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643034 (US20240000767, Example 113 | diamix-N-(5-Chloro-2-...) Show SMILES C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1cc(Cl)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642991 (US20240000767, Example 115 | US20240000767, Exampl...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3CC3)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643042 (US20240000767, Example 121 | rac-N-[(3,5-Difluorop...) Show SMILES CCCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643038 (US20240000767, Example 117 | diamix-N-[1-(2,5-Difl...) Show SMILES CC(NC(=O)c1cnc(s1)N1CCC(C(F)C1)N1CCC[C@@H](C)C1)c1cc(F)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643060 (US20240000767, Example 139) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3ccc(Cl)cc3C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642987 (US20240000767, Example 131 | US20240000767, Exampl...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3(F)F)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643055 (US20240000767, Example 134 | diamix-2-[4-(1,1-Difl...) Show SMILES FC1CN(CCC1N1CCCC2(CC2(F)F)C1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643024 (US20240000767, Example 103 | rac-N-[(3,5-Difluorop...) Show SMILES CC(C)C1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643030 (US20240000767, Example 109 | rac-2-[3-(Cyclobutylo...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OC2CCC2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643054 (US20240000767, Example 133 | rac-N-[(3,5-Difluorop...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)c2ccccc2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643066 (US20240000767, Example 145) Show SMILES COc1ccc2CN(CCc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM458963 ((4-{[2-(4-Bromophenyl)imidazo[,2-a]pyridin-3-yl]me...) Show SMILES Brc1ccc(cc1)-c1nc2ccccn2c1CN1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C24H27BrN4O/c25-20-10-8-18(9-11-20)23-21(29-12-4-3-7-22(29)26-23)17-27-13-15-28(16-14-27)24(30)19-5-1-2-6-19/h3-4,7-12,19H,1-2,5-6,13-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532051 (3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl]m...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ccccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643033 (US20240000767, Example 112 | diamix-N-[(3,5-Difluo...) Show SMILES C[C@@H]1CCCN(C1)C1CCN(CC1F)c1nc(co1)C(=O)NCc1ncc(F)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643068 (US20240000767, Example 148) Show SMILES COCCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643035 (2-[(3R)-3-(Cyclopropylmethoxy)[1,4′-bipiperi...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCC[C@H](C2)OCC2CC2)c(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532241 (US11208422, Example 82 | US11208422, Example 83) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642986 (2-[4-(5-Azaspiro[2.5]octan-5-yl)piperidin-1-yl]-N-...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515603 (US11098063, Example 109) Show SMILES CCN(CC)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643031 (US20240000767, Example 110 | rac-2-{3-[(3,3-Difluo...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OC2CC(F)(F)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574217 (CHEMBL4866383 | US20240000767, Example 126) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532228 (US11208422, Example 69 | US11208422, Example 88 | ...) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ccccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643067 (US20240000767, Example 146) Show SMILES Cc1ccc2CN(CCc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM643065 (US20240000767, Example 144) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3cccc(F)c3C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515513 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642987 (US20240000767, Example 131 | US20240000767, Exampl...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3(F)F)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM642989 (US20240000767, Example 67 | rac-2-[3-(Cyclopropylm...) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532162 (3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM458968 (US10759794, Example 47) Show SMILES COc1cccc(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C25H24BrN5O2/c1-33-23-7-4-5-20(27-23)25(32)30-15-13-29(14-16-30)17-21-24(18-8-10-19(26)11-9-18)28-22-6-2-3-12-31(21)22/h2-12H,13-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...				US Patent US10759794 (2020) BindingDB Entry DOI: 10.7270/Q2KK9FW6
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574215 (CHEMBL4878875 | US20240000767, Example 102) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50574217 (CHEMBL4866383 | US20240000767, Example 126) Show SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532051 (3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl]m...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ccccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532051 (3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl]m...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ccccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair

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