Compile Data Set for Download or QSAR

Found 27 hits with Last Name = 'harasawa' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022147 (CHEMBL3299117) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc(OCCc2cccc(c2)C(F)(F)F)n1 Show InChI InChI=1S/C23H21F3N2O3/c24-23(25,26)19-7-1-4-16(14-19)10-13-31-21-9-3-8-20(28-21)17-5-2-6-18(15-17)22(30)27-11-12-29/h1-9,14-15,29H,10-13H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at GPR52 (unknown origin)				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460264 (CHEMBL4229128) Show SMILES COCCNC(=O)c1cn(nc1C)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C24H22F3N3O2S/c1-15-20(23(31)28-9-10-32-2)14-30(29-15)21-8-4-6-17-13-19(33-22(17)21)12-16-5-3-7-18(11-16)24(25,26)27/h3-8,11,13-14H,9-10,12H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.60	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022152 (CHEMBL3299018) Show SMILES COc1ccc(cc1)-c1ccnc(NCCc2ccc(OC)c(OC)c2C)n1 Show InChI InChI=1S/C22H25N3O3/c1-15-16(7-10-20(27-3)21(15)28-4)11-13-23-22-24-14-12-19(25-22)17-5-8-18(26-2)9-6-17/h5-10,12,14H,11,13H2,1-4H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022153 (CHEMBL3299119) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2oc(Cc3cccc(c3)C(F)(F)F)cc12 Show InChI InChI=1S/C25H20F3NO3/c26-25(27,28)19-7-1-4-16(12-19)13-20-15-22-21(8-3-9-23(22)32-20)17-5-2-6-18(14-17)24(31)29-10-11-30/h1-9,12,14-15,30H,10-11,13H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022156 (CHEMBL3299120) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)oc12 Show InChI InChI=1S/C25H20F3NO3/c26-25(27,28)20-8-1-4-16(12-20)13-21-15-18-6-3-9-22(23(18)32-21)17-5-2-7-19(14-17)24(31)29-10-11-30/h1-9,12,14-15,30H,10-11,13H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022157 (CHEMBL3299121) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2sc(Cc3cccc(c3)C(F)(F)F)cc12 Show InChI InChI=1S/C25H20F3NO2S/c26-25(27,28)19-7-1-4-16(12-19)13-20-15-22-21(8-3-9-23(22)32-20)17-5-2-6-18(14-17)24(31)29-10-11-30/h1-9,12,14-15,30H,10-11,13H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022158 (CHEMBL3299122) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C25H20F3NO2S/c26-25(27,28)20-8-1-4-16(12-20)13-21-15-18-6-3-9-22(23(18)32-21)17-5-2-7-19(14-17)24(31)29-10-11-30/h1-9,12,14-15,30H,10-11,13H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022159 (CHEMBL3299123) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2nn(Cc3cccc(c3)C(F)(F)F)cc12 Show InChI InChI=1S/C24H20F3N3O2/c25-24(26,27)19-7-1-4-16(12-19)14-30-15-21-20(8-3-9-22(21)29-30)17-5-2-6-18(13-17)23(32)28-10-11-31/h1-9,12-13,15,31H,10-11,14H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022162 (CHEMBL3299124) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2cn(Cc3cccc(c3)C(F)(F)F)nc12 Show InChI InChI=1S/C24H20F3N3O2/c25-24(26,27)20-8-1-4-16(12-20)14-30-15-19-7-3-9-21(22(19)29-30)17-5-2-6-18(13-17)23(32)28-10-11-31/h1-9,12-13,15,31H,10-11,14H2,(H,28,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022164 (CHEMBL3299125) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2OC(Cc3cccc(c3)C(F)(F)F)Cc12 Show InChI InChI=1S/C25H22F3NO3/c26-25(27,28)19-7-1-4-16(12-19)13-20-15-22-21(8-3-9-23(22)32-20)17-5-2-6-18(14-17)24(31)29-10-11-30/h1-9,12,14,20,30H,10-11,13,15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022165 (CHEMBL3297807) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc2CC(Cc3cccc(c3)C(F)(F)F)Oc12 Show InChI InChI=1S/C25H22F3NO3/c26-25(27,28)20-8-1-4-16(12-20)13-21-15-18-6-3-9-22(23(18)32-21)17-5-2-7-19(14-17)24(31)29-10-11-30/h1-9,12,14,21,30H,10-11,13,15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022166 (CHEMBL3297808) Show SMILES Cc1c(Cc2cccc(c2)C(F)(F)F)oc2cccc(-c3cccc(c3)C(=O)NCCO)c12 Show InChI InChI=1S/C26H22F3NO3/c1-16-23(14-17-5-2-8-20(13-17)26(27,28)29)33-22-10-4-9-21(24(16)22)18-6-3-7-19(15-18)25(32)30-11-12-31/h2-10,13,15,31H,11-12,14H2,1H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022169 (CHEMBL3297809) Show SMILES Cc1c(Cc2cccc(c2)C(F)(F)F)oc2c(cccc12)-c1cccc(c1)C(=O)NCCO Show InChI InChI=1S/C26H22F3NO3/c1-16-21-9-4-10-22(18-6-3-7-19(15-18)25(32)30-11-12-31)24(21)33-23(16)14-17-5-2-8-20(13-17)26(27,28)29/h2-10,13,15,31H,11-12,14H2,1H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022170 (CHEMBL3297810) Show SMILES NC(=O)CNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C25H19F3N2O2S/c26-25(27,28)19-8-1-4-15(10-19)11-20-13-17-6-3-9-21(23(17)33-20)16-5-2-7-18(12-16)24(32)30-14-22(29)31/h1-10,12-13H,11,14H2,(H2,29,31)(H,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022189 (CHEMBL3297811) Show SMILES COCCNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C26H22F3NO2S/c1-32-12-11-30-25(31)20-8-3-6-18(15-20)23-10-4-7-19-16-22(33-24(19)23)14-17-5-2-9-21(13-17)26(27,28)29/h2-10,13,15-16H,11-12,14H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022190 (CHEMBL3298233) Show SMILES COCCNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cc(F)cc(Cl)c3)sc12 Show InChI InChI=1S/C25H21ClFNO2S/c1-30-9-8-28-25(29)19-6-2-4-17(13-19)23-7-3-5-18-14-22(31-24(18)23)12-16-10-20(26)15-21(27)11-16/h2-7,10-11,13-15H,8-9,12H2,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022254 (CHEMBL3298234) Show SMILES NC(=O)CNC(=O)c1cccc(c1)-c1ccc(F)c2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C25H18F4N2O2S/c26-21-8-7-19(15-4-2-5-16(11-15)24(33)31-13-22(30)32)23-20(21)12-18(34-23)10-14-3-1-6-17(9-14)25(27,28)29/h1-9,11-12H,10,13H2,(H2,30,32)(H,31,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460255 (CHEMBL4226295) Show SMILES Cc1nn(cc1C(=O)NCCO)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C23H20F3N3O2S/c1-14-19(22(31)27-8-9-30)13-29(28-14)20-7-3-5-16-12-18(32-21(16)20)11-15-4-2-6-17(10-15)23(24,25)26/h2-7,10,12-13,30H,8-9,11H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460256 (CHEMBL4226751) Show SMILES Cc1c(C(=O)NCCO)c(CO)nn1-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C24H22F3N3O3S/c1-14-21(23(33)28-8-9-31)19(13-32)29-30(14)20-7-3-5-16-12-18(34-22(16)20)11-15-4-2-6-17(10-15)24(25,26)27/h2-7,10,12,31-32H,8-9,11,13H2,1H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	146	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460257 (CHEMBL4228912) Show SMILES Cc1nn(c(CO)c1C(=O)NCCO)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C24H22F3N3O3S/c1-14-21(23(33)28-8-9-31)20(13-32)30(29-14)19-7-3-5-16-12-18(34-22(16)19)11-15-4-2-6-17(10-15)24(25,26)27/h2-7,10,12,31-32H,8-9,11,13H2,1H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair				3D Structure (crystal)
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460258 (CHEMBL4228734) Show SMILES Cn1nc(cc1C(=O)NCCO)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C23H20F3N3O2S/c1-29-20(22(31)27-8-9-30)13-19(28-29)18-7-3-5-15-12-17(32-21(15)18)11-14-4-2-6-16(10-14)23(24,25)26/h2-7,10,12-13,30H,8-9,11H2,1H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460259 (CHEMBL4226750) Show SMILES COCCNC(=O)c1cnn(c1C)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C24H22F3N3O2S/c1-15-20(23(31)28-9-10-32-2)14-29-30(15)21-8-4-6-17-13-19(33-22(17)21)12-16-5-3-7-18(11-16)24(25,26)27/h3-8,11,13-14H,9-10,12H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460260 (CHEMBL4226225) Show SMILES OCCNC(=O)c1cnn(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C22H18F3N3O2S/c23-22(24,25)17-5-1-3-14(9-17)10-18-11-15-4-2-6-19(20(15)31-18)28-13-16(12-27-28)21(30)26-7-8-29/h1-6,9,11-13,29H,7-8,10H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460261 (CHEMBL4226253) Show SMILES COCCNC(=O)c1cnn(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C23H20F3N3O2S/c1-31-9-8-27-22(30)17-13-28-29(14-17)20-7-3-5-16-12-19(32-21(16)20)11-15-4-2-6-18(10-15)23(24,25)26/h2-7,10,12-14H,8-9,11H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460262 (CHEMBL4229063) Show SMILES Cc1nn(c(C)c1C(=O)NCCO)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C24H22F3N3O2S/c1-14-21(23(32)28-9-10-31)15(2)30(29-14)20-8-4-6-17-13-19(33-22(17)20)12-16-5-3-7-18(11-16)24(25,26)27/h3-8,11,13,31H,9-10,12H2,1-2H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50460263 (CHEMBL4226695) Show SMILES COCCNC(=O)c1c(C)nn(c1C)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 Show InChI InChI=1S/C25H24F3N3O2S/c1-15-22(24(32)29-10-11-33-3)16(2)31(30-15)21-9-5-7-18-14-20(34-23(18)21)13-17-6-4-8-19(12-17)25(26,27)28/h4-9,12,14H,10-11,13H2,1-3H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR52 expressed in CHO cells assessed as increase in cAMP level after 30 mins by AlphaScreen assay				Bioorg Med Chem 26: 1598-1608 (2018) Article DOI: 10.1016/j.bmc.2018.02.005 BindingDB Entry DOI: 10.7270/Q2377CC3
					More data for this Ligand-Target Pair
G-protein coupled receptor 52 (Homo sapiens (Human))	BDBM50022151 (CHEMBL3299118) Show SMILES OCCNC(=O)c1cccc(c1)-c1cccc(OCCc2cc(F)cc(Cl)c2)n1 Show InChI InChI=1S/C22H20ClFN2O3/c23-18-11-15(12-19(24)14-18)7-10-29-21-6-2-5-20(26-21)16-3-1-4-17(13-16)22(28)25-8-9-27/h1-6,11-14,27H,7-10H2,(H,25,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Agonist activity at GPR52 (unknown origin)				J Med Chem 57: 5226-37 (2014) Article DOI: 10.1021/jm5002919 BindingDB Entry DOI: 10.7270/Q2CR5VZD
					More data for this Ligand-Target Pair