| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 52 |
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| Ligand | BDBM50460257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1769217 (CHEMBL4221329) |
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| EC50 | 21±n/a nM |
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| Citation |  Nakahata, T; Tokumaru, K; Ito, Y; Ishii, N; Setoh, M; Shimizu, Y; Harasawa, T; Aoyama, K; Hamada, T; Kori, M; Aso, K Design and synthesis of 1-(1-benzothiophen-7-yl)-1H-pyrazole, a novel series of G protein-coupled receptor 52 (GPR52) agonists. Bioorg Med Chem26:1598-1608 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 52 |
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| Name: | G-protein coupled receptor 52 |
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| Synonyms: | GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41366.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108391 |
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| Residue: | 361 |
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| Sequence: | MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
I
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| BDBM50460257 |
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| n/a |
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| Name | BDBM50460257 |
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| Synonyms: | CHEMBL4228912 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22F3N3O3S |
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| Mol. Mass. | 489.51 |
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| SMILES | Cc1nn(c(CO)c1C(=O)NCCO)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)sc12 |
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| Structure | 
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