Compile Data Set for Download or QSAR

Found 207 hits with Last Name = 'haubmann' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole was tested				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079644 (2-[4-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...) Show SMILES N#CC(=Cc1cc(CN2CCN(CC2)c2ccccc2)c[nH]1)C#N |(-.67,-3.67,;.64,-4.48,;1.76,-5.54,;3.25,-5.1,;4.37,-6.15,;5.87,-5.87,;6.62,-7.22,;8.09,-7.69,;9.22,-6.66,;9.93,-5.28,;11.59,-5.84,;12.83,-5.39,;12.13,-6.76,;10.37,-6.2,;13.99,-4.37,;13.68,-2.87,;14.83,-1.85,;16.3,-2.34,;16.61,-3.85,;15.44,-4.86,;5.56,-8.34,;4.16,-7.68,;1.41,-7.04,;.98,-8.51,)| Show InChI InChI=1S/C19H19N5/c20-12-16(13-21)10-18-11-17(14-22-18)15-23-6-8-24(9-7-23)19-4-2-1-3-5-19/h1-5,10-11,14,22H,6-9,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079645 (2-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c(C=C(C#N)C#N)c2)CC1 |(17.45,-1.32,;16.3,-2.34,;14.83,-1.85,;13.68,-2.87,;13.99,-4.37,;15.44,-4.86,;16.61,-3.85,;12.83,-5.39,;11.59,-5.84,;9.93,-5.28,;9.22,-6.66,;8.09,-7.69,;6.62,-7.22,;5.56,-8.34,;4.16,-7.68,;4.37,-6.15,;3.25,-5.1,;1.76,-5.54,;.64,-4.48,;-.67,-3.67,;1.41,-7.04,;.98,-8.51,;5.87,-5.87,;10.37,-6.2,;12.13,-6.76,)| Show InChI InChI=1S/C19H18ClN5/c20-17-1-3-19(4-2-17)25-7-5-24(6-8-25)14-16-10-18(23-13-16)9-15(11-21)12-22/h1-4,9-10,13,23H,5-8,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on High Affinity Site of Bovine Dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079642 (2-[5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...) Show SMILES N#CC(=Cc1ccc(CN2CCN(CC2)c2ccccc2)[nH]1)C#N |(-2.04,-8.9,;-.7,-8.14,;.75,-7.65,;1.08,-6.16,;2.55,-5.68,;3.01,-4.22,;4.55,-4.22,;5.03,-5.68,;6.5,-6.16,;7.63,-5.13,;8.34,-3.76,;9.99,-4.32,;11.24,-3.85,;10.53,-5.23,;8.79,-4.67,;12.39,-2.84,;12.08,-1.34,;13.23,-.33,;14.7,-.82,;15,-2.31,;13.85,-3.34,;3.78,-6.59,;1.89,-8.69,;2.99,-9.77,)| Show InChI InChI=1S/C19H19N5/c20-13-16(14-21)12-17-6-7-18(22-17)15-23-8-10-24(11-9-23)19-4-2-1-3-5-19/h1-7,12,22H,8-11,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079646 (2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2ccc(C=C(C#N)C#N)[nH]2)CC1 |(17.42,-1.31,;16.28,-2.34,;14.81,-1.85,;13.66,-2.87,;13.97,-4.37,;15.41,-4.86,;16.58,-3.85,;12.8,-5.38,;11.57,-5.83,;9.91,-5.27,;9.21,-6.65,;8.07,-7.68,;6.6,-7.21,;6.13,-5.74,;4.59,-5.74,;4.11,-7.21,;2.66,-7.68,;2.33,-9.18,;.87,-9.66,;-.47,-10.43,;3.47,-10.22,;4.55,-11.3,;5.36,-8.12,;10.36,-6.18,;12.1,-6.74,)| Show InChI InChI=1S/C19H18ClN5/c20-16-1-5-19(6-2-16)25-9-7-24(8-10-25)14-18-4-3-17(23-18)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]spiperone was te...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D4.4 expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2L				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity on High Affinity Site of Dopamine receptor D2S				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2S				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity on High Affinity Site of Dopamine receptor D2L				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Ability of the compound to displace [3H]-spiperone from the cloned human Dopamine receptor D2S stably expressed in Chinese hamster ovary (CHO) cells ...				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2 .Tested for ability to displace the radioliga...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole at t...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2S				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2S				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioliga...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2L				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Ability of the compound to displace [3H]-spiperone from the cloned human Dopamine receptor D2L stably expressed in Chinese hamster ovary (CHO) cells ...				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioliga...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2L				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioliga...				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]-Spiperone				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50082166 (1-Benzyl-4-(2-oxazol-5-yl-pyrrol-1-yl)-piperidine ...) Show SMILES C(N1CCC(CC1)n1cccc1-c1cnco1)c1ccccc1 Show InChI InChI=1S/C19H21N3O/c1-2-5-16(6-3-1)14-21-11-8-17(9-12-21)22-10-4-7-18(22)19-13-20-15-23-19/h1-7,10,13,15,17H,8-9,11-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D4.4 expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079641 (2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc[nH]c2C=C(C#N)C#N)CC1 |(4.53,1.33,;3.38,.32,;1.91,.81,;.75,-.22,;1.07,-1.71,;2.52,-2.2,;3.69,-1.2,;-.09,-2.74,;.22,-4.23,;-.91,-5.25,;-2.37,-4.78,;-3.5,-5.81,;-4.97,-5.34,;-6.16,-6.3,;-7.46,-5.48,;-7.07,-3.99,;-5.53,-3.9,;-4.69,-2.61,;-5.39,-1.24,;-6.93,-1.17,;-8.46,-1,;-4.56,.05,;-4,1.49,;-2.7,-3.27,;-1.56,-2.26,)| Show InChI InChI=1S/C19H18ClN5/c20-17-1-3-18(4-2-17)25-9-7-24(8-10-25)14-16-5-6-23-19(16)11-15(12-21)13-22/h1-6,11,23H,7-10,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50082170 (1-Benzyl-4-(3-oxazol-5-yl-pyrrol-1-yl)-piperidine ...) Show SMILES C(N1CCC(CC1)n1ccc(c1)-c1cnco1)c1ccccc1 Show InChI InChI=1S/C19H21N3O/c1-2-4-16(5-3-1)13-21-9-7-18(8-10-21)22-11-6-17(14-22)19-12-20-15-23-19/h1-6,11-12,14-15,18H,7-10,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D4.4 expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]-Spiperone				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity on High Affinity Site of Dopamine receptor D2L				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50085333 (CHEMBL163087 | Dipropyl-(4-trimethylsilanylethynyl...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C[Si](C)(C)C |c:10| Show InChI InChI=1S/C17H31NSi/c1-6-13-18(14-7-2)17-10-8-16(9-11-17)12-15-19(3,4)5/h8,17H,6-7,9-11,13-14H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079643 (2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-y...) Show SMILES N#CC(=Cc1[nH]ccc1CN1CCN(CC1)c1ccccc1)C#N |(-8.12,-.83,;-6.59,-.99,;-5.05,-1.07,;-4.35,-2.44,;-5.19,-3.74,;-6.73,-3.82,;-7.13,-5.31,;-5.82,-6.13,;-4.63,-5.17,;-3.15,-5.64,;-2.02,-4.61,;-.56,-5.08,;.57,-4.05,;.26,-2.55,;-1.21,-2.09,;-2.35,-3.11,;1.43,-1.54,;2.87,-2.03,;4.04,-1.01,;3.74,.49,;2.27,.98,;1.11,-.03,;-4.22,.23,;-3.66,1.67,)| Show InChI InChI=1S/C19H19N5/c20-13-16(14-21)12-19-17(6-7-22-19)15-23-8-10-24(11-9-23)18-4-2-1-3-5-18/h1-7,12,22H,8-11,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Erlangen - Nürnberg Curated by ChEMBL					Assay Description Binding affinity of compound towards human cloned Dopamine receptor D4.4 expressed in CHO cells using [3H]-spiperone as radioligand				Bioorg Med Chem Lett 9: 1969-72 (1999) BindingDB Entry DOI: 10.7270/Q2BP020F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50085331 ((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...) Show SMILES CCCN(CCC)C1CCC(=CC1)C#C |c:10| Show InChI InChI=1S/C14H23N/c1-4-11-15(12-5-2)14-9-7-13(6-3)8-10-14/h3,7,14H,4-5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Dissociation constant of compound on one-site model Dopamine receptor D4.4				J Med Chem 43: 756-62 (2000) BindingDB Entry DOI: 10.7270/Q27W6CXP
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50082167 (1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-2-carbaldeh...) Show SMILES O=Cc1cccn1C1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C17H20N2O/c20-14-17-7-4-10-19(17)16-8-11-18(12-9-16)13-15-5-2-1-3-6-15/h1-7,10,14,16H,8-9,11-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human Dopamine receptor D4.4 expressed in CHO cells				Bioorg Med Chem Lett 9: 3143-6 (1999) BindingDB Entry DOI: 10.7270/Q2W0955D
					More data for this Ligand-Target Pair

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