Compile Data Set for Download or QSAR

Found 75 hits with Last Name = 'hirasawa' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552414 (CHEMBL4791592) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50552408 (CHEMBL4750971) Show SMILES Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at rat TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Fluo-...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50207645 (CHEMBL3971179) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C23H20F2N2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM based ...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552420 (CHEMBL4759917) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccc(F)cc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552416 (CHEMBL4763262) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(F)cc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207659 (CHEMBL3944840) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H21ClN2O3/c1-15(17-10-7-11-18(24)14-17)26(23(29)19-12-5-6-13-20(19)27)21(22(25)28)16-8-3-2-4-9-16/h2-15,21,27H,1H3,(H2,25,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552412 (CHEMBL4752955) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(F)cc2F)C(=O)c1cccnc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552413 (CHEMBL4780270) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1N)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552411 (CHEMBL4762495) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1cccnc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552418 (CHEMBL4749804) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cccc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552419 (CHEMBL4785984) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccc(Cl)cc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552410 (CHEMBL4795385) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1cccnc1N)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207647 (CHEMBL3926952) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(Cl)c1 |r| Show InChI InChI=1S/C23H20ClFN2O2/c1-15(18-12-19(24)14-20(25)13-18)27(23(29)17-10-6-3-7-11-17)21(22(26)28)16-8-4-2-5-9-16/h2-15,21H,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207568 (CHEMBL3980601) Show SMILES COC(=O)[C@H](N(Cc1cccc(OC)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H23NO4/c1-28-21-15-9-10-18(16-21)17-25(23(26)20-13-7-4-8-14-20)22(24(27)29-2)19-11-5-3-6-12-19/h3-16,22H,17H2,1-2H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552408 (CHEMBL4750971) Show SMILES Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207657 (CHEMBL3917717) Show SMILES COc1cccc(c1)[C@@H](C)N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C24H24N2O3/c1-17(20-14-9-15-21(16-20)29-2)26(24(28)19-12-7-4-8-13-19)22(23(25)27)18-10-5-3-6-11-18/h3-17,22H,1-2H3,(H2,25,27)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552423 (CHEMBL4748099) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2ccccc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552415 (CHEMBL4749601) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cc(Cl)cc2F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552409 (CHEMBL4785621) Show SMILES COc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207649 (CHEMBL3907933) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1C)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H23ClN2O2/c1-16-9-6-7-14-21(16)24(29)27(17(2)19-12-8-13-20(25)15-19)22(23(26)28)18-10-4-3-5-11-18/h3-15,17,22H,1-2H3,(H2,26,28)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207658 (CHEMBL3898642) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H21ClN2O2/c1-16(19-13-8-14-20(24)15-19)26(23(28)18-11-6-3-7-12-18)21(22(25)27)17-9-4-2-5-10-17/h2-16,21H,1H3,(H2,25,27)/t16-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 Show InChI InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	414	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207670 (CHEMBL3889978) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1N)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H22ClN3O2/c1-15(17-10-7-11-18(24)14-17)27(23(29)19-12-5-6-13-20(19)25)21(22(26)28)16-8-3-2-4-9-16/h2-15,21H,25H2,1H3,(H2,26,28)/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 Show InChI InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium increase by Fluo-4 AM based...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 Show InChI InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	448	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium increase by Fluo-4 AM based...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 Show InChI InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant full length TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced calcium increase preinc...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552417 (CHEMBL4758145) Show SMILES NC(=O)[C@H](N([C@@H]1CCc2c1cccc2Cl)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207688 (CHEMBL3916922) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccc(C)cc1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H23ClN2O2/c1-16-11-13-19(14-12-16)24(29)27(17(2)20-9-6-10-21(25)15-20)22(23(26)28)18-7-4-3-5-8-18/h3-15,17,22H,1-2H3,(H2,26,28)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207646 (CHEMBL3959823) Show SMILES Cc1cccc(CN([C@@H](C(N)=O)c2ccccc2)C(=O)c2ccccc2)c1 |r| Show InChI InChI=1S/C23H22N2O2/c1-17-9-8-10-18(15-17)16-25(23(27)20-13-6-3-7-14-20)21(22(24)26)19-11-4-2-5-12-19/h2-15,21H,16H2,1H3,(H2,24,26)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207651 (CHEMBL3934736) Show SMILES COc1cccc(CN([C@@H](C(N)=O)c2ccccc2)C(=O)c2ccccc2)c1 |r| Show InChI InChI=1S/C23H22N2O3/c1-28-20-14-8-9-17(15-20)16-25(23(27)19-12-6-3-7-13-19)21(22(24)26)18-10-4-2-5-11-18/h2-15,21H,16H2,1H3,(H2,24,26)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552425 (CHEMBL4786793) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552424 (CHEMBL4745090) Show SMILES NC(=O)[C@H](N([C@@H]1CCCc2ccccc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552428 (CHEMBL4764800) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)c(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207662 (CHEMBL3943602) Show SMILES COc1cccc(CN([C@@H](C(N)=O)c2ccccc2)C(=O)c2cccs2)c1 |r| Show InChI InChI=1S/C21H20N2O3S/c1-26-17-10-5-7-15(13-17)14-23(21(25)18-11-6-12-27-18)19(20(22)24)16-8-3-2-4-9-16/h2-13,19H,14H2,1H3,(H2,22,24)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552426 (CHEMBL4777635) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1C |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207664 (CHEMBL3935896) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1cccc(C)c1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H23ClN2O2/c1-16-8-6-12-20(14-16)24(29)27(17(2)19-11-7-13-21(25)15-19)22(23(26)28)18-9-4-3-5-10-18/h3-15,17,22H,1-2H3,(H2,26,28)/t17-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552427 (CHEMBL4751372) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207660 (CHEMBL3898903) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1cccnc1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C22H20ClN3O2/c1-15(17-9-5-11-19(23)13-17)26(22(28)18-10-6-12-25-14-18)20(21(24)27)16-7-3-2-4-8-16/h2-15,20H,1H3,(H2,24,27)/t15-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207573 (CHEMBL3897350) Show SMILES NC(=O)[C@H](N(Cc1cccc(Cl)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H19ClN2O2/c23-19-13-7-8-16(14-19)15-25(22(27)18-11-5-2-6-12-18)20(21(24)26)17-9-3-1-4-10-17/h1-14,20H,15H2,(H2,24,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50552421 (CHEMBL4763338) Show SMILES NC(=O)[C@H](N([C@@H]1COc2ccccc12)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPM8 transfected in HEK293T cells assessed as reduction in menthol-induced calcium influx measured after 60 mins by Flu...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115903 BindingDB Entry DOI: 10.7270/Q2CV4NCZ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207644 (CHEMBL3918002) Show SMILES C[C@@H](N([C@@H](C(N)=O)c1cccnc1)C(=O)c1ccccc1)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C22H20ClN3O2/c1-15(17-9-5-11-19(23)13-17)26(22(28)16-7-3-2-4-8-16)20(21(24)27)18-10-6-12-25-14-18/h2-15,20H,1H3,(H2,24,27)/t15-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207689 (CHEMBL3970879) Show SMILES NC(=O)[C@H](N(Cc1cccc(OC(F)(F)F)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H19F3N2O3/c24-23(25,26)31-19-13-7-8-16(14-19)15-28(22(30)18-11-5-2-6-12-18)20(21(27)29)17-9-3-1-4-10-17/h1-14,20H,15H2,(H2,27,29)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207655 (CHEMBL3899728) Show SMILES NC(=O)[C@H](N(Cc1cccc(c1)C(F)(F)F)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C23H19F3N2O2/c24-23(25,26)19-13-7-8-16(14-19)15-28(22(30)18-11-5-2-6-12-18)20(21(27)29)17-9-3-1-4-10-17/h1-14,20H,15H2,(H2,27,29)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207668 (CHEMBL3908765) Show SMILES NC(=O)[C@H](N(Cc1ccccc1Cl)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H19ClN2O2/c23-19-14-8-7-13-18(19)15-25(22(27)17-11-5-2-6-12-17)20(21(24)26)16-9-3-1-4-10-16/h1-14,20H,15H2,(H2,24,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207661 (CHEMBL3927831) Show SMILES NC(=O)[C@H](N(Cc1cccc(F)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H19FN2O2/c23-19-13-7-8-16(14-19)15-25(22(27)18-11-5-2-6-12-18)20(21(24)26)17-9-3-1-4-10-17/h1-14,20H,15H2,(H2,24,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207665 (CHEMBL3973096) Show SMILES COc1cc(CN(CC(N)=O)C(=O)c2cccs2)ccc1OCc1ccc(F)cc1 Show InChI InChI=1S/C22H21FN2O4S/c1-28-19-11-16(6-9-18(19)29-14-15-4-7-17(23)8-5-15)12-25(13-21(24)26)22(27)20-3-2-10-30-20/h2-11H,12-14H2,1H3,(H2,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207667 (CHEMBL3972562) Show SMILES CNC(=O)[C@H](N(Cc1cccc(OC)c1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H24N2O3/c1-25-23(27)22(19-11-5-3-6-12-19)26(24(28)20-13-7-4-8-14-20)17-18-10-9-15-21(16-18)29-2/h3-16,22H,17H2,1-2H3,(H,25,27)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50207654 (CHEMBL3900408) Show SMILES NC(=O)[C@H](N(Cc1ccccc1)C(=O)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N2O2/c23-21(25)20(18-12-6-2-7-13-18)24(16-17-10-4-1-5-11-17)22(26)19-14-8-3-9-15-19/h1-15,20H,16H2,(H2,23,25)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium increase by Fluo-4 AM base...				Bioorg Med Chem 25: 727-742 (2017) Article DOI: 10.1016/j.bmc.2016.11.049 BindingDB Entry DOI: 10.7270/Q2445PF7
					More data for this Ligand-Target Pair

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