Compile Data Set for Download or QSAR

Found 13 hits with Last Name = 'hour' and Initial = 'tc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM35440 (ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340832 (3-[3-(Piperidin-1-yl)-propoxy]xanthone | CHEMBL176...) Show SMILES O=c1c2ccccc2oc2cc(OCCCN3CCCCC3)ccc12 Show InChI InChI=1S/C21H23NO3/c23-21-17-7-2-3-8-19(17)25-20-15-16(9-10-18(20)21)24-14-6-13-22-11-4-1-5-12-22/h2-3,7-10,15H,1,4-6,11-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340843 (3-Hydroxy-6-[3-(methylpiperazylamino)-propoxy]xant...) Show SMILES CN1CCN(CCCOc2ccc3c(c2)oc2cc(O)ccc2c3=O)CC1 Show InChI InChI=1S/C21H24N2O4/c1-22-8-10-23(11-9-22)7-2-12-26-16-4-6-18-20(14-16)27-19-13-15(24)3-5-17(19)21(18)25/h3-6,13-14,24H,2,7-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340834 (3-[3-(4-Methylpiperazino)-propoxy]xanthone | CHEMB...) Show SMILES CN1CCN(CCCOc2ccc3c(c2)oc2ccccc2c3=O)CC1 Show InChI InChI=1S/C21H24N2O3/c1-22-10-12-23(13-11-22)9-4-14-25-16-7-8-18-20(15-16)26-19-6-3-2-5-17(19)21(18)24/h2-3,5-8,15H,4,9-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340841 (3-[3-(Diethylamino)-propoxy]-6-hydroxyxanthone | C...) Show SMILES CCN(CC)CCCOc1ccc2c(c1)oc1cc(O)ccc1c2=O Show InChI InChI=1S/C20H23NO4/c1-3-21(4-2)10-5-11-24-15-7-9-17-19(13-15)25-18-12-14(22)6-8-16(18)20(17)23/h6-9,12-13,22H,3-5,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340836 (3-[3-(Diethylamino)-propoxy]xanthone | CHEMBL17612...) Show SMILES CCN(CC)CCCOc1ccc2c(c1)oc1ccccc1c2=O Show InChI InChI=1S/C20H23NO3/c1-3-21(4-2)12-7-13-23-15-10-11-17-19(14-15)24-18-9-6-5-8-16(18)20(17)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340839 (3-[3-(Cyclopropylamino)-propoxy]-6-hydroxyxanthone...) Show SMILES Oc1ccc2c(c1)oc1cc(OCCCNC3CC3)ccc1c2=O Show InChI InChI=1S/C19H19NO4/c21-13-4-6-15-17(10-13)24-18-11-14(5-7-16(18)19(15)22)23-9-1-8-20-12-2-3-12/h4-7,10-12,20-21H,1-3,8-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340833 (3-[3-(Pyrrolidin-1-yl)-propoxy]xanthone | CHEMBL17...) Show SMILES O=c1c2ccccc2oc2cc(OCCCN3CCCC3)ccc12 Show InChI InChI=1S/C20H21NO3/c22-20-16-6-1-2-7-18(16)24-19-14-15(8-9-17(19)20)23-13-5-12-21-10-3-4-11-21/h1-2,6-9,14H,3-5,10-13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340838 (3-Hydroxy-6-[3-(pyrrolidin-1-yl)-propoxy]xanthone ...) Show SMILES Oc1ccc2c(c1)oc1cc(OCCCN3CCCC3)ccc1c2=O Show InChI InChI=1S/C20H21NO4/c22-14-4-6-16-18(12-14)25-19-13-15(5-7-17(19)20(16)23)24-11-3-10-21-8-1-2-9-21/h4-7,12-13,22H,1-3,8-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340840 (3-[3-(Cyclohexylamino)-propoxy]-6-hydroxyxanthone ...) Show SMILES Oc1ccc2c(c1)oc1cc(OCCCNC3CCCCC3)ccc1c2=O Show InChI InChI=1S/C22H25NO4/c24-16-7-9-18-20(13-16)27-21-14-17(8-10-19(21)22(18)25)26-12-4-11-23-15-5-2-1-3-6-15/h7-10,13-15,23-24H,1-6,11-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340837 (3-Hydroxy-6-[3-(piperidin-1-yl)-propoxy]xanthone |...) Show SMILES Oc1ccc2c(c1)oc1cc(OCCCN3CCCCC3)ccc1c2=O Show InChI InChI=1S/C21H23NO4/c23-15-5-7-17-19(13-15)26-20-14-16(6-8-18(20)21(17)24)25-12-4-11-22-9-2-1-3-10-22/h5-8,13-14,23H,1-4,9-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340842 (3-Hydroxy-6-[3-(piperazino)-propoxy]xanthone | CHE...) Show SMILES Oc1ccc2c(c1)oc1cc(OCCCN3CCNCC3)ccc1c2=O Show InChI InChI=1S/C20H22N2O4/c23-14-2-4-16-18(12-14)26-19-13-15(3-5-17(19)20(16)24)25-11-1-8-22-9-6-21-7-10-22/h2-5,12-13,21,23H,1,6-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50340835 (3-[3-(Piperazino)-propoxy]xanthone | CHEMBL1761211) Show SMILES O=c1c2ccccc2oc2cc(OCCCN3CCNCC3)ccc12 Show InChI InChI=1S/C20H22N2O3/c23-20-16-4-1-2-5-18(16)25-19-14-15(6-7-17(19)20)24-13-3-10-22-11-8-21-9-12-22/h1-2,4-7,14,21H,3,8-13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 mins				Eur J Med Chem 46: 1222-31 (2011) Article DOI: 10.1016/j.ejmech.2011.01.043 BindingDB Entry DOI: 10.7270/Q2RB74X9
					More data for this Ligand-Target Pair