Compile Data Set for Download or QSAR

Found 492 hits with Last Name = 'huger' and Initial = 'fp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50007692 (8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the presence of Zn				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50452855 (Isoptpo Hyoscine | Scopolamine) Show SMILES [H][C@@]12O[C@@]1([H])[C@]1([H])C[C@@H](C[C@@]2([H])N1C)OC(=O)[C@H](CO)c1ccccc1 |r,TLB:14:8:12:1.3,2:1:12:8.7.9,2:3:12:8.7.9| Show InChI InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15+,16+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the absence of Zn				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) Show SMILES Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225539 (CHEMBL164940) Show SMILES Oc1nc2ccccc2n1CCCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C22H23FN4O2/c23-16-6-7-17-20(14-16)29-25-21(17)15-8-12-26(13-9-15)10-3-11-27-19-5-2-1-4-18(19)24-22(27)28/h1-2,4-7,14-15H,3,8-13H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50048608 (CHEMBL154488 | Indol-1-yl-pyridin-4-yl-amine) Show SMILES N(c1ccncc1)n1ccc2ccccc12 Show InChI InChI=1S/C13H11N3/c1-2-4-13-11(3-1)7-10-16(13)15-12-5-8-14-9-6-12/h1-10H,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10972 ((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...) Show SMILES [H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)NCCCCCCC)ccc1N2C Show InChI InChI=1S/C21H33N3O2/c1-5-6-7-8-9-13-22-20(25)26-16-10-11-18-17(15-16)21(2)12-14-23(3)19(21)24(18)4/h10-11,15,19H,5-9,12-14H2,1-4H3,(H,22,25)/t19-,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase.				Bioorg Med Chem Lett 6: 625-630 (1996) Article DOI: 10.1016/0960-894X(96)00072-8 BindingDB Entry DOI: 10.7270/Q22J6BVC
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50007498 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES O=C1CC2(CCCC2)CCN1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H32N4O2S/c28-21-18-23(8-3-4-9-23)10-12-27(21)29-17-5-11-25-13-15-26(16-14-25)22-19-6-1-2-7-20(19)30-24-22/h1-2,6-7H,3-5,8-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50007483 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES OC1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H32N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7,20,28H,3-5,8-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM9349 ((2Z)-but-2-enedioic acid; 9-amino-6-chloro-1,2,3,4...) Show SMILES Nc1c2C(O)CCCc2nc2cc(Cl)ccc12 Show InChI InChI=1S/C13H13ClN2O/c14-7-4-5-8-10(6-7)16-9-2-1-3-11(17)12(9)13(8)15/h4-6,11,17H,1-3H2,(H2,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.7	n/a	n/a	n/a	n/a	7.4	25
Hoechst-Roussel Pharmaceuticals, Inc.					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman.				J Med Chem 32: 1805-13 (1989) Article DOI: 10.1021/jm00128a024 BindingDB Entry DOI: 10.7270/Q24Q7S6Z
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225526 (CHEMBL350575) Show SMILES Cc1[nH]c2ccccc2c1CCCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C24H26FN3O/c1-16-19(20-5-2-3-7-22(20)26-16)6-4-12-28-13-10-17(11-14-28)24-21-9-8-18(25)15-23(21)29-27-24/h2-3,5,7-9,15,17,26H,4,6,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225528 (CHEMBL168104) Show SMILES Fc1ccc2c(CCCN3CCC(CC3)c3noc4cc(F)ccc34)noc2c1 Show InChI InChI=1S/C22H21F2N3O2/c23-15-3-5-17-19(25-28-20(17)12-15)2-1-9-27-10-7-14(8-11-27)22-18-6-4-16(24)13-21(18)29-26-22/h3-6,12-14H,1-2,7-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007692 (8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50007481 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H30N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7H,3-5,8-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225534 (CHEMBL351954) Show SMILES Fc1ccc(cc1)C(CCCN1CCC(CC1)c1noc2cc(F)ccc12)c1ccc(F)cc1 Show InChI InChI=1S/C28H27F3N2O/c29-22-7-3-19(4-8-22)25(20-5-9-23(30)10-6-20)2-1-15-33-16-13-21(14-17-33)28-26-12-11-24(31)18-27(26)34-32-28/h3-12,18,21,25H,1-2,13-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007692 (8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50048589 (CHEMBL152842 | Indol-1-yl-methyl-pyridin-4-yl-amin...) Show SMILES CN(c1ccncc1)n1ccc2ccccc12 Show InChI InChI=1S/C14H13N3/c1-16(13-6-9-15-10-7-13)17-11-8-12-4-2-3-5-14(12)17/h2-11H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225543 (CHEMBL165301) Show SMILES Oc1nc2ccccc2n1CCCN1CCC(CC1)c1noc2cc(Cl)ccc12 Show InChI InChI=1S/C22H23ClN4O2/c23-16-6-7-17-20(14-16)29-25-21(17)15-8-12-26(13-9-15)10-3-11-27-19-5-2-1-4-18(19)24-22(27)28/h1-2,4-7,14-15H,3,8-13H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007505 (8-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H30F3N3O3/c24-23(25,26)18-5-3-6-19(15-18)28-12-10-27(11-13-28)9-4-14-32-29-20(30)16-22(17-21(29)31)7-1-2-8-22/h3,5-6,15H,1-2,4,7-14,16-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007498 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES O=C1CC2(CCCC2)CCN1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H32N4O2S/c28-21-18-23(8-3-4-9-23)10-12-27(21)29-17-5-11-25-13-15-26(16-14-25)22-19-6-1-2-7-20(19)30-24-22/h1-2,6-7H,3-5,8-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) Show SMILES Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007494 (8-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propoxy}...) Show SMILES Clc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C22H30ClN3O3/c23-18-5-3-6-19(15-18)25-12-10-24(11-13-25)9-4-14-29-26-20(27)16-22(17-21(26)28)7-1-2-8-22/h3,5-6,15H,1-2,4,7-14,16-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225524 (CHEMBL165775) Show SMILES Cc1[nH]c2ccccc2c1CCCN1CCC(CC1)c1noc2ccccc12 Show InChI InChI=1S/C24H27N3O/c1-17-19(20-7-2-4-10-22(20)25-17)9-6-14-27-15-12-18(13-16-27)24-21-8-3-5-11-23(21)28-26-24/h2-5,7-8,10-11,18,25H,6,9,12-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225542 (CHEMBL166095) Show SMILES Fc1ccc2c(CCCN3CCC(CC3)c3noc4ccccc34)noc2c1 Show InChI InChI=1S/C22H22FN3O2/c23-16-7-8-17-19(24-28-21(17)14-16)5-3-11-26-12-9-15(10-13-26)22-18-4-1-2-6-20(18)27-25-22/h1-2,4,6-8,14-15H,3,5,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007496 (8-{3-[4-(3-Methylsulfanyl-phenyl)-piperazin-1-yl]-...) Show SMILES CSc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H33N3O3S/c1-30-20-7-4-6-19(16-20)25-13-11-24(12-14-25)10-5-15-29-26-21(27)17-23(18-22(26)28)8-2-3-9-23/h4,6-7,16H,2-3,5,8-15,17-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007495 (9-Hydroxy-8-{3-[4-(2-methoxy-phenyl)-piperazin-1-y...) Show SMILES COc1ccccc1N1CCN(CCCON2C(O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H35N3O4/c1-29-20-8-3-2-7-19(20)25-14-12-24(13-15-25)11-6-16-30-26-21(27)17-23(18-22(26)28)9-4-5-10-23/h2-3,7-8,21,27H,4-6,9-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50231956 ((Z)-8-bromo-4-methyl-3-(methylimino)-1,2,3,4-tetra...) Show SMILES CN=C1CCc2c1n(C)c1ccc(OC(=O)N(C)C)c(Br)c21 |w:1.0| Show InChI InChI=1S/C16H18BrN3O2/c1-18-10-6-5-9-13-11(20(4)15(9)10)7-8-12(14(13)17)22-16(21)19(2)3/h7-8H,5-6H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase.				Bioorg Med Chem Lett 6: 625-630 (1996) Article DOI: 10.1016/0960-894X(96)00072-8 BindingDB Entry DOI: 10.7270/Q22J6BVC
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225545 (CHEMBL165857) Show SMILES Oc1nc2ccccc2n1CCCN1CCC(CC1)c1noc2cccc(F)c12 Show InChI InChI=1S/C22H23FN4O2/c23-16-5-3-8-19-20(16)21(25-29-19)15-9-13-26(14-10-15)11-4-12-27-18-7-2-1-6-17(18)24-22(27)28/h1-3,5-8,15H,4,9-14H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225538 (CHEMBL166311) Show SMILES Fc1ccc2c(CCCN3CCC(CC3)c3noc4ccc(F)cc34)noc2c1 Show InChI InChI=1S/C22H21F2N3O2/c23-15-4-6-20-18(12-15)22(26-28-20)14-7-10-27(11-8-14)9-1-2-19-17-5-3-16(24)13-21(17)29-25-19/h3-6,12-14H,1-2,7-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007492 (8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy...) Show SMILES COc1ccccc1N1CCN(CCCON2CCC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H35N3O3/c1-28-21-8-3-2-7-20(21)25-16-14-24(15-17-25)12-6-18-29-26-13-11-23(19-22(26)27)9-4-5-10-23/h2-3,7-8H,4-6,9-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225535 (CHEMBL349840) Show SMILES Fc1ccc2c(CCCN3CCC(CC3)c3noc4cc(Cl)ccc34)noc2c1 Show InChI InChI=1S/C22H21ClFN3O2/c23-15-3-5-18-20(12-15)29-26-22(18)14-7-10-27(11-8-14)9-1-2-19-17-6-4-16(24)13-21(17)28-25-19/h3-6,12-14H,1-2,7-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001888 ((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...) Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50004303 (CHEMBL344115 | Phenyl-piperidin-4-yl-methanone) Show SMILES O=C(C1CCNCC1)c1ccccc1 Show InChI InChI=1S/C12H15NO/c14-12(10-4-2-1-3-5-10)11-6-8-13-9-7-11/h1-5,11,13H,6-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50342601 (CHEMBL1255901 | Huperzine A) Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 |r,c:18,TLB:1:2:11.5.4:17.14.15| Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Acetylcholinesterase inhibitory activity in rat striatal homogenates				J Med Chem 38: 3645-51 (1995) BindingDB Entry DOI: 10.7270/Q2X34Z3G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007483 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES OC1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H32N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7,20,28H,3-5,8-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225522 (CHEMBL165576) Show SMILES Cc1[nH]c2ccccc2c1CCCN1CCC(CC1)c1noc2cc(Cl)ccc12 Show InChI InChI=1S/C24H26ClN3O/c1-16-19(20-5-2-3-7-22(20)26-16)6-4-12-28-13-10-17(11-14-28)24-21-9-8-18(25)15-23(21)29-27-24/h2-3,5,7-9,15,17,26H,4,6,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007484 (8-[3-(4-m-Tolyl-piperazin-1-yl)-propoxy]-8-aza-spi...) Show SMILES Cc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H33N3O3/c1-19-6-4-7-20(16-19)25-13-11-24(12-14-25)10-5-15-29-26-21(27)17-23(18-22(26)28)8-2-3-9-23/h4,6-7,16H,2-3,5,8-15,17-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50288976 (CHEMBL155350 | Methyl-carbamic acid 8-chloro-3-[(Z...) Show SMILES CCN=C1CCc2c1n(C)c1ccc(OC(=O)NC)c(Cl)c21 |w:2.1| Show InChI InChI=1S/C16H18ClN3O2/c1-4-19-10-6-5-9-13-11(20(3)15(9)10)7-8-12(14(13)17)22-16(21)18-2/h7-8H,4-6H2,1-3H3,(H,18,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of monoamine oxidase-A(MAO-A).				Bioorg Med Chem Lett 6: 625-630 (1996) Article DOI: 10.1016/0960-894X(96)00072-8 BindingDB Entry DOI: 10.7270/Q22J6BVC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007480 (8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy...) Show SMILES COc1ccccc1N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C23H33N3O4/c1-29-20-8-3-2-7-19(20)25-14-12-24(13-15-25)11-6-16-30-26-21(27)17-23(18-22(26)28)9-4-5-10-23/h2-3,7-8H,4-6,9-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007481 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H30N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7H,3-5,8-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50048600 (CHEMBL154541 | Ethyl-indol-1-yl-pyridin-4-yl-amine) Show SMILES CCN(c1ccncc1)n1ccc2ccccc12 Show InChI InChI=1S/C15H15N3/c1-2-17(14-7-10-16-11-8-14)18-12-9-13-5-3-4-6-15(13)18/h3-12H,2H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225531 (CHEMBL349632) Show SMILES Oc1nc2ccccc2n1CCCN1CCC(CC1)c1noc2ccc(F)cc12 Show InChI InChI=1S/C22H23FN4O2/c23-16-6-7-20-17(14-16)21(25-29-20)15-8-12-26(13-9-15)10-3-11-27-19-5-2-1-4-18(19)24-22(27)28/h1-2,4-7,14-15H,3,8-13H2,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225525 (CHEMBL164973) Show SMILES Fc1ccc(cc1)C(CCCN1CCC(CC1)c1noc2ccc(F)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C28H27F3N2O/c29-22-7-3-19(4-8-22)25(20-5-9-23(30)10-6-20)2-1-15-33-16-13-21(14-17-33)28-26-18-24(31)11-12-27(26)34-32-28/h3-12,18,21,25H,1-2,13-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiroperidol in rat striatal tissue				J Med Chem 28: 761-9 (1985) BindingDB Entry DOI: 10.7270/Q2F47RCQ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50048580 (CHEMBL29835 | Indol-1-yl-propyl-pyridin-4-yl-amine...) Show SMILES CCCN(c1ccncc1)n1ccc2ccccc12 Show InChI InChI=1S/C16H17N3/c1-2-12-18(15-7-10-17-11-8-15)19-13-9-14-5-3-4-6-16(14)19/h3-11,13H,2,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against [3H]idazoxan binding to Alpha-2 adrenergic receptor in rat cortex, in the presence of GPP				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007481 (8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C23H30N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7H,3-5,8-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissue				J Med Chem 34: 1068-72 (1991) BindingDB Entry DOI: 10.7270/Q2D21Z6P
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50288977 (CHEMBL160836 | Methyl-carbamic acid 8-bromo-3-[(Z)...) Show SMILES CCN=C1CCc2c1n(C)c1ccc(OC(=O)NC)c(Br)c21 |w:2.1| Show InChI InChI=1S/C16H18BrN3O2/c1-4-19-10-6-5-9-13-11(20(3)15(9)10)7-8-12(14(13)17)22-16(21)18-2/h7-8H,4-6H2,1-3H3,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of acetylcholinesterase.				Bioorg Med Chem Lett 6: 625-630 (1996) Article DOI: 10.1016/0960-894X(96)00072-8 BindingDB Entry DOI: 10.7270/Q22J6BVC
					More data for this Ligand-Target Pair

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