Compile Data Set for Download or QSAR

Found 65 hits with Last Name = 'iacobazzi' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1 Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423895 (CHEMBL2312702) Show SMILES CC(C)c1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C24H24O3/c1-17(2)21-10-6-7-11-22(21)19-12-14-20(15-13-19)27-23(24(25)26)16-18-8-4-3-5-9-18/h3-15,17,23H,16H2,1-2H3,(H,25,26)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423896 (CHEMBL2312701) Show SMILES CCc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C23H22O3/c1-2-18-10-6-7-11-21(18)19-12-14-20(15-13-19)26-22(23(24)25)16-17-8-4-3-5-9-17/h3-15,22H,2,16H2,1H3,(H,24,25)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423897 (CHEMBL2312700) Show SMILES COc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O4/c1-25-20-10-6-5-9-19(20)17-11-13-18(14-12-17)26-21(22(23)24)15-16-7-3-2-4-8-16/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423898 (CHEMBL2312718) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1-c1ccccc1 |r| Show InChI InChI=1S/C27H22O3/c28-27(29)26(19-20-9-3-1-4-10-20)30-23-17-15-22(16-18-23)25-14-8-7-13-24(25)21-11-5-2-6-12-21/h1-18,26H,19H2,(H,28,29)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423899 (CHEMBL2312717) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C22H17F3O3/c23-22(24,25)19-9-5-4-8-18(19)16-10-12-17(13-11-16)28-20(21(26)27)14-15-6-2-1-3-7-15/h1-13,20H,14H2,(H,26,27)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423900 (CHEMBL2312716) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1F |r| Show InChI InChI=1S/C21H17FO3/c22-19-9-5-4-8-18(19)16-10-12-17(13-11-16)25-20(21(23)24)14-15-6-2-1-3-7-15/h1-13,20H,14H2,(H,23,24)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423901 (CHEMBL2312715) Show SMILES Cc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1C |r| Show InChI InChI=1S/C23H22O3/c1-16-8-6-7-11-20(16)21-13-12-19(14-17(21)2)26-22(23(24)25)15-18-9-4-3-5-10-18/h3-14,22H,15H2,1-2H3,(H,24,25)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423902 (CHEMBL2312714) Show SMILES Cc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-7-5-6-10-20(16)18-11-13-19(14-12-18)25-21(22(23)24)15-17-8-3-2-4-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423903 (CHEMBL2312713) Show SMILES Cc1cccc(c1)-c1ccc(OC(Cc2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C22H20O3/c1-16-6-5-9-19(14-16)18-10-12-20(13-11-18)25-21(22(23)24)15-17-7-3-2-4-8-17/h2-14,21H,15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423904 (CHEMBL2312712) Show SMILES Cc1ccc(cc1)-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-7-9-18(10-8-16)19-11-13-20(14-12-19)25-21(22(23)24)15-17-5-3-2-4-6-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423905 (CHEMBL2312711) Show SMILES Cc1cccc(C)c1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C23H22O3/c1-16-7-6-8-17(2)22(16)19-11-13-20(14-12-19)26-21(23(24)25)15-18-9-4-3-5-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423906 (CHEMBL2312710) Show SMILES Cc1cc(OC(Cc2ccccc2)C(O)=O)cc(C)c1-c1ccccc1 Show InChI InChI=1S/C23H22O3/c1-16-13-20(14-17(2)22(16)19-11-7-4-8-12-19)26-21(23(24)25)15-18-9-5-3-6-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423907 (CHEMBL2312709) Show SMILES Cc1cc(cc(C)c1O[C@@H](Cc1ccccc1)C(O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C23H22O3/c1-16-13-20(19-11-7-4-8-12-19)14-17(2)22(16)26-21(23(24)25)15-18-9-5-3-6-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423908 (CHEMBL2312708) Show SMILES Cc1cc(O[C@@H](Cc2ccccc2)C(O)=O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-14-19(12-13-20(16)18-10-6-3-7-11-18)25-21(22(23)24)15-17-8-4-2-5-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50423909 (CHEMBL2312707) Show SMILES Cc1cc(ccc1O[C@@H](Cc1ccccc1)C(O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-14-19(18-10-6-3-7-11-18)12-13-20(16)25-21(22(23)24)15-17-8-4-2-5-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28759 ((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C21H18O3/c22-21(23)20(15-16-7-3-1-4-8-16)24-19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20H,15H2,(H,22,23)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423910 (CHEMBL2312706) Show SMILES OC(=O)C(Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1CCc1ccccc1 Show InChI InChI=1S/C29H26O3/c30-29(31)28(21-23-11-5-2-6-12-23)32-26-19-17-25(18-20-26)27-14-8-7-13-24(27)16-15-22-9-3-1-4-10-22/h1-14,17-20,28H,15-16,21H2,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423911 (CHEMBL2312705) Show SMILES CCCCCc1ccccc1-c1ccc(OC(Cc2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C26H28O3/c1-2-3-5-12-21-13-8-9-14-24(21)22-15-17-23(18-16-22)29-25(26(27)28)19-20-10-6-4-7-11-20/h4,6-11,13-18,25H,2-3,5,12,19H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423912 (CHEMBL2312704) Show SMILES CCCc1ccccc1-c1ccc(OC(Cc2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C24H24O3/c1-2-8-19-11-6-7-12-22(19)20-13-15-21(16-14-20)27-23(24(25)26)17-18-9-4-3-5-10-18/h3-7,9-16,23H,2,8,17H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423913 (CHEMBL2312703) Show SMILES CC(C)c1ccccc1-c1ccc(O[C@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C24H24O3/c1-17(2)21-10-6-7-11-22(21)19-12-14-20(15-13-19)27-23(24(25)26)16-18-8-4-3-5-9-18/h3-15,17,23H,16H2,1-2H3,(H,25,26)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423895 (CHEMBL2312702) Show SMILES CC(C)c1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C24H24O3/c1-17(2)21-10-6-7-11-22(21)19-12-14-20(15-13-19)27-23(24(25)26)16-18-8-4-3-5-9-18/h3-15,17,23H,16H2,1-2H3,(H,25,26)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423896 (CHEMBL2312701) Show SMILES CCc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C23H22O3/c1-2-18-10-6-7-11-21(18)19-12-14-20(15-13-19)26-22(23(24)25)16-17-8-4-3-5-9-17/h3-15,22H,2,16H2,1H3,(H,24,25)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423897 (CHEMBL2312700) Show SMILES COc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O4/c1-25-20-10-6-5-9-19(20)17-11-13-18(14-12-17)26-21(22(23)24)15-16-7-3-2-4-8-16/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423898 (CHEMBL2312718) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1-c1ccccc1 |r| Show InChI InChI=1S/C27H22O3/c28-27(29)26(19-20-9-3-1-4-10-20)30-23-17-15-22(16-18-23)25-14-8-7-13-24(25)21-11-5-2-6-12-21/h1-18,26H,19H2,(H,28,29)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423899 (CHEMBL2312717) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C22H17F3O3/c23-22(24,25)19-9-5-4-8-18(19)16-10-12-17(13-11-16)28-20(21(26)27)14-15-6-2-1-3-7-15/h1-13,20H,14H2,(H,26,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423900 (CHEMBL2312716) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1F |r| Show InChI InChI=1S/C21H17FO3/c22-19-9-5-4-8-18(19)16-10-12-17(13-11-16)25-20(21(23)24)14-15-6-2-1-3-7-15/h1-13,20H,14H2,(H,23,24)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423901 (CHEMBL2312715) Show SMILES Cc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1C |r| Show InChI InChI=1S/C23H22O3/c1-16-8-6-7-11-20(16)21-13-12-19(14-17(21)2)26-22(23(24)25)15-18-9-4-3-5-10-18/h3-14,22H,15H2,1-2H3,(H,24,25)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423902 (CHEMBL2312714) Show SMILES Cc1ccccc1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-7-5-6-10-20(16)18-11-13-19(14-12-18)25-21(22(23)24)15-17-8-3-2-4-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423903 (CHEMBL2312713) Show SMILES Cc1cccc(c1)-c1ccc(OC(Cc2ccccc2)C(O)=O)cc1 Show InChI InChI=1S/C22H20O3/c1-16-6-5-9-19(14-16)18-10-12-20(13-11-18)25-21(22(23)24)15-17-7-3-2-4-8-17/h2-14,21H,15H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423904 (CHEMBL2312712) Show SMILES Cc1ccc(cc1)-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-7-9-18(10-8-16)19-11-13-20(14-12-19)25-21(22(23)24)15-17-5-3-2-4-6-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423905 (CHEMBL2312711) Show SMILES Cc1cccc(C)c1-c1ccc(O[C@@H](Cc2ccccc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C23H22O3/c1-16-7-6-8-17(2)22(16)19-11-13-20(14-12-19)26-21(23(24)25)15-18-9-4-3-5-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423906 (CHEMBL2312710) Show SMILES Cc1cc(OC(Cc2ccccc2)C(O)=O)cc(C)c1-c1ccccc1 Show InChI InChI=1S/C23H22O3/c1-16-13-20(14-17(2)22(16)19-11-7-4-8-12-19)26-21(23(24)25)15-18-9-5-3-6-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423907 (CHEMBL2312709) Show SMILES Cc1cc(cc(C)c1O[C@@H](Cc1ccccc1)C(O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C23H22O3/c1-16-13-20(19-11-7-4-8-12-19)14-17(2)22(16)26-21(23(24)25)15-18-9-5-3-6-10-18/h3-14,21H,15H2,1-2H3,(H,24,25)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423908 (CHEMBL2312708) Show SMILES Cc1cc(O[C@@H](Cc2ccccc2)C(O)=O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-14-19(12-13-20(16)18-10-6-3-7-11-18)25-21(22(23)24)15-17-8-4-2-5-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50423909 (CHEMBL2312707) Show SMILES Cc1cc(ccc1O[C@@H](Cc1ccccc1)C(O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C22H20O3/c1-16-14-19(18-10-6-3-7-11-18)12-13-20(16)25-21(22(23)24)15-17-8-4-2-5-9-17/h2-14,21H,15H2,1H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28759 ((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) Show SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C21H18O3/c22-21(23)20(15-16-7-3-1-4-8-16)24-19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20H,15H2,(H,22,23)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Universit� degli Studi di Bari&quo Curated by ChEMBL					Assay Description Transactivation of GAL4-fused human PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene assay				J Med Chem 56: 60-72 (2013) Article DOI: 10.1021/jm301018z BindingDB Entry DOI: 10.7270/Q25140HR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50085041 (2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...) Show SMILES CCCc1c(O)c(ccc1OCCCOc1ccc(OCC(O)=O)cc1)C(C)=O Show InChI InChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Binding affinity to PPARdelta (unknown origin) assessed as kinetic dissociation constant by SPR assay				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235984 (CHEMBL4064900) Show SMILES CC(Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235985 (CHEMBL4092600) Show SMILES C[C@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235986 (CHEMBL4073499) Show SMILES C[C@@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50085041 (2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...) Show SMILES CCCc1c(O)c(ccc1OCCCOc1ccc(OCC(O)=O)cc1)C(C)=O Show InChI InChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235985 (CHEMBL4092600) Show SMILES C[C@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.0160	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235986 (CHEMBL4073499) Show SMILES C[C@@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.0250	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	0.360	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50235986 (CHEMBL4073499) Show SMILES C[C@@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.0950	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50235985 (CHEMBL4092600) Show SMILES C[C@H](Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O |r| Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.0990	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50235984 (CHEMBL4064900) Show SMILES CC(Oc1ccc(Cc2ccc(OCc3coc(n3)-c3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C26H23NO5/c1-18(26(28)29)32-24-13-9-20(10-14-24)15-19-7-11-23(12-8-19)30-16-22-17-31-25(27-22)21-5-3-2-4-6-21/h2-14,17-18H,15-16H2,1H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair

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