Compile Data Set for Download or QSAR

Found 156 hits with Last Name = 'jenkins-west' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106179 (CHEMBL125327 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NC[C@H]1CCCC1(C)C Show InChI InChI=1S/C21H29N3O2/c1-4-5-8-18-23-20(26-24-18)16-11-9-15(10-12-16)19(25)22-14-17-7-6-13-21(17,2)3/h9-12,17H,4-8,13-14H2,1-3H3,(H,22,25)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106169 (CHEMBL338973 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NC[C@@H]1CCCC1(C)C Show InChI InChI=1S/C21H29N3O2/c1-4-5-8-18-23-20(26-24-18)16-11-9-15(10-12-16)19(25)22-14-17-7-6-13-21(17,2)3/h9-12,17H,4-8,13-14H2,1-3H3,(H,22,25)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301472 (7-(3,4-dichlorophenyl)-6-(5-fluoro-1-methyl-1H-ben...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2cc(F)ccc2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H16Cl2FN5/c1-11-19(21-27-16-10-13(24)4-6-17(16)28(21)2)20(29-18(26-11)7-8-25-29)12-3-5-14(22)15(23)9-12/h3-10,19-20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106167 (CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1nc(CC2CC2)no1 Show InChI InChI=1S/C21H27N3O2/c1-21(2)11-3-4-17(21)13-22-19(25)15-7-9-16(10-8-15)20-23-18(24-26-20)12-14-5-6-14/h7-10,14,17H,3-6,11-13H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptor				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106167 (CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1nc(CC2CC2)no1 Show InChI InChI=1S/C21H27N3O2/c1-21(2)11-3-4-17(21)13-22-19(25)15-7-9-16(10-8-15)20-23-18(24-26-20)12-14-5-6-14/h7-10,14,17H,3-6,11-13H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106178 (4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...) Show SMILES CCCCc1noc(n1)-c1ccc(cc1)C(=O)NCCC(C)(C)C Show InChI InChI=1S/C19H27N3O2/c1-5-6-7-16-21-18(24-22-16)15-10-8-14(9-11-15)17(23)20-13-12-19(2,3)4/h8-11H,5-7,12-13H2,1-4H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106168 (CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CCCc1noc(n1)-c1ccc(cc1)C(=O)NCC1CCCC1(C)C Show InChI InChI=1S/C20H27N3O2/c1-4-6-17-22-19(25-23-17)15-10-8-14(9-11-15)18(24)21-13-16-7-5-12-20(16,2)3/h8-11,16H,4-7,12-13H2,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptor				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106168 (CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CCCc1noc(n1)-c1ccc(cc1)C(=O)NCC1CCCC1(C)C Show InChI InChI=1S/C20H27N3O2/c1-4-6-17-22-19(25-23-17)15-10-8-14(9-11-15)18(24)21-13-16-7-5-12-20(16,2)3/h8-11,16H,4-7,12-13H2,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301473 (7-(3,4-dichlorophenyl)-6-(5-fluoro-1-methyl-1H-ben...) Show SMILES COCC1=Nc2ccnn2C(C1c1nc2cc(F)ccc2n1C)c1ccc(Cl)c(Cl)c1 |t:3| Show InChI InChI=1S/C22H18Cl2FN5O/c1-29-18-6-4-13(25)10-16(18)28-22(29)20-17(11-31-2)27-19-7-8-26-30(19)21(20)12-3-5-14(23)15(24)9-12/h3-10,20-21H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50061218 ((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)\C=C\c2ccc(Cl)cc2Cl)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C25H19Cl2N3O2/c1-30-21-10-6-5-9-19(21)23(17-7-3-2-4-8-17)29-24(25(30)32)28-22(31)14-12-16-11-13-18(26)15-20(16)27/h2-15,24H,1H3,(H,28,31)/b14-12+/t24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50099581 (CHEMBL288131 | N-((2R,3R)-3-(4-ethylphenylsulfonam...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r| Show InChI InChI=1S/C25H26N2O5S/c1-3-16-7-11-21(12-8-16)33(30,31)27-24-22-15-19(10-9-17(22)14-23(24)28)26-25(29)18-5-4-6-20(13-18)32-2/h4-13,15,23-24,27-28H,3,14H2,1-2H3,(H,26,29)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106176 (CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1noc(CCC(F)(F)F)n1 Show InChI InChI=1S/C20H24F3N3O2/c1-19(2)10-3-4-15(19)12-24-18(27)14-7-5-13(6-8-14)17-25-16(28-26-17)9-11-20(21,22)23/h5-8,15H,3-4,9-12H2,1-2H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Bindind affinity values obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brain				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106176 (CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...) Show SMILES CC1(C)CCCC1CNC(=O)c1ccc(cc1)-c1noc(CCC(F)(F)F)n1 Show InChI InChI=1S/C20H24F3N3O2/c1-19(2)10-3-4-15(19)12-24-18(27)14-7-5-13(6-8-14)17-25-16(28-26-17)9-11-20(21,22)23/h5-8,15H,3-4,9-12H2,1-2H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301471 (7-(3,4-dichlorophenyl)-6-(5-fluoro-1-propyl-1H-ben...) Show SMILES CCCn1c(nc2cc(F)ccc12)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:32| Show InChI InChI=1S/C23H20Cl2FN5/c1-3-10-30-19-7-5-15(26)12-18(19)29-23(30)21-13(2)28-20-8-9-27-31(20)22(21)14-4-6-16(24)17(25)11-14/h4-9,11-12,21-22H,3,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306906 (((R)-7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...) Show SMILES CC1=Nc2ccnn2[C@@H](C1C(=O)N1CCC[C@H]1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3/t20-,22?,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301469 (6-(5-chloro-1-ethyl-1H-benzo[d]imidazol-2-yl)-7-(3...) Show SMILES CCn1c(nc2cc(Cl)ccc12)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:31| Show InChI InChI=1S/C22H18Cl3N5/c1-3-29-18-7-5-14(23)11-17(18)28-22(29)20-12(2)27-19-8-9-26-30(19)21(20)13-4-6-15(24)16(25)10-13/h4-11,20-21H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211550 ((3S,4R)-4-(N-butyl-4-ethylphenylsulfonamido)-3-hyd...) Show SMILES CCCCN([C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)NCCc1ccccc1)S(=O)(=O)c1ccc(CC)cc1 Show InChI InChI=1S/C32H40N2O5S/c1-5-7-21-34(40(37,38)26-16-13-23(6-2)14-17-26)29-27-22-25(15-18-28(27)39-32(3,4)30(29)35)31(36)33-20-19-24-11-9-8-10-12-24/h8-18,22,29-30,35H,5-7,19-21H2,1-4H3,(H,33,36)/t29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301456 (7-(3,4-dichlorophenyl)-6-(4-fluoro-1-methyl-1H-ben...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2c(F)cccc2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H16Cl2FN5/c1-11-18(21-27-19-15(24)4-3-5-16(19)28(21)2)20(29-17(26-11)8-9-25-29)12-6-7-13(22)14(23)10-12/h3-10,18,20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301459 (6-(5-chloro-1-methyl-1H-benzo[d]imidazol-2-yl)-7-(...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2cc(Cl)ccc2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H16Cl3N5/c1-11-19(21-27-16-10-13(22)4-6-17(16)28(21)2)20(29-18(26-11)7-8-25-29)12-3-5-14(23)15(24)9-12/h3-10,19-20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254617 (7-(3,4-dichlorophenyl)-5-methyl-N,N-dipropyl-4,7-d...) Show SMILES CCCN(CCC)C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:26| Show InChI InChI=1S/C20H24Cl2N4O/c1-4-10-25(11-5-2)20(27)18-13(3)24-17-8-9-23-26(17)19(18)14-6-7-15(21)16(22)12-14/h6-9,12,18-19H,4-5,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306891 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306891 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H21Cl2FN4O/c1-14-22(24(32)30-12-2-3-20(30)15-4-7-17(27)8-5-15)23(31-21(29-14)10-11-28-31)16-6-9-18(25)19(26)13-16/h4-11,13,20,22-23H,2-3,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254617 (7-(3,4-dichlorophenyl)-5-methyl-N,N-dipropyl-4,7-d...) Show SMILES CCCN(CCC)C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:26| Show InChI InChI=1S/C20H24Cl2N4O/c1-4-10-25(11-5-2)20(27)18-13(3)24-17-8-9-23-26(17)19(18)14-6-7-15(21)16(22)12-14/h6-9,12,18-19H,4-5,10-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254809 ((R)-(7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropy...) Show SMILES CC1=Nc2ccnn2[C@@H](C1C(=O)N1CCN(CC1)c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C24H22Cl2FN5O/c1-15-22(24(33)31-12-10-30(11-13-31)18-5-3-17(27)4-6-18)23(32-21(29-15)8-9-28-32)16-2-7-19(25)20(26)14-16/h2-9,14,22-23H,10-13H2,1H3/t22?,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301457 (6-(7-chloro-1-methyl-1H-benzo[d]imidazol-2-yl)-7-(...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2cccc(Cl)c2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H16Cl3N5/c1-11-18(21-27-16-5-3-4-14(23)20(16)28(21)2)19(29-17(26-11)8-9-25-29)12-6-7-13(22)15(24)10-12/h3-10,18-19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301452 (7-(3,4-dichlorophenyl)-5-methyl-6-(1-methyl-1H-ben...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2ccccc2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H17Cl2N5/c1-12-19(21-26-16-5-3-4-6-17(16)27(21)2)20(28-18(25-12)9-10-24-28)13-7-8-14(22)15(23)11-13/h3-11,19-20H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211518 ((3S,4R)-N-ethyl-4-(4-ethylphenylsulfonamido)-3-hyd...) Show SMILES CCN(CCNc1ccccc1)C(=O)c1ccc2OC(C)(C)[C@@H](O)[C@H](NS(=O)(=O)c3ccc(CC)cc3)c2c1 Show InChI InChI=1S/C30H37N3O5S/c1-5-21-12-15-24(16-13-21)39(36,37)32-27-25-20-22(14-17-26(25)38-30(3,4)28(27)34)29(35)33(6-2)19-18-31-23-10-8-7-9-11-23/h7-17,20,27-28,31-32,34H,5-6,18-19H2,1-4H3/t27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211521 (CHEMBL388762 | N-((3S,4R)-6-(5-amino-3-phenyl-1H-p...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)n1nc(cc1N)-c1ccccc1 Show InChI InChI=1S/C29H30N4O5S/c1-4-18-10-13-21(14-11-18)39(36,37)32-26-22-16-20(12-15-24(22)38-29(2,3)27(26)34)28(35)33-25(30)17-23(31-33)19-8-6-5-7-9-19/h5-17,26-27,32,34H,4,30H2,1-3H3/t26-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254736 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCN(CC1)c1ccccc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H23Cl2N5O/c1-16-22(24(32)30-13-11-29(12-14-30)18-5-3-2-4-6-18)23(31-21(28-16)9-10-27-31)17-7-8-19(25)20(26)15-17/h2-10,15,22-23H,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211547 (CHEMBL228808 | N-((3R,4S)-6-((R)-2-((2,6-dimethylp...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@@H]1[C@@H](O)C(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@@H]1CNc1c(C)cccc1C Show InChI InChI=1S/C33H41N3O5S/c1-6-23-12-15-26(16-13-23)42(39,40)35-30-27-19-24(14-17-28(27)41-33(4,5)31(30)37)32(38)36-18-8-11-25(36)20-34-29-21(2)9-7-10-22(29)3/h7,9-10,12-17,19,25,30-31,34-35,37H,6,8,11,18,20H2,1-5H3/t25-,30+,31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306905 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES Cc1cc(no1)[C@@H]1CCCN1C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |r,c:32| Show InChI InChI=1S/C22H21Cl2N5O2/c1-12-10-17(27-31-12)18-4-3-9-28(18)22(30)20-13(2)26-19-7-8-25-29(19)21(20)14-5-6-15(23)16(24)11-14/h5-8,10-11,18,20-21H,3-4,9H2,1-2H3/t18-,20?,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254698 (5-(1-cyclohexylvinyl)-4-(3,4-dimethylphenyl)-6-met...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCCC1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C19H20Cl2N4O/c1-12-17(19(26)24-9-3-2-4-10-24)18(25-16(23-12)7-8-22-25)13-5-6-14(20)15(21)11-13/h5-8,11,17-18H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301470 (6-(5-chloro-1-isopropyl-1H-benzo[d]imidazol-2-yl)-...) Show SMILES CC(C)n1c(nc2cc(Cl)ccc12)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |c:32| Show InChI InChI=1S/C23H20Cl3N5/c1-12(2)30-19-7-5-15(24)11-18(19)29-23(30)21-13(3)28-20-8-9-27-31(20)22(21)14-4-6-16(25)17(26)10-14/h4-12,21-22H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254656 (7-(3,4-dichlorophenyl)-5-methyl-N-phenethyl-4,7-di...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)NCCc1ccccc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C22H20Cl2N4O/c1-14-20(22(29)25-11-9-15-5-3-2-4-6-15)21(28-19(27-14)10-12-26-28)16-7-8-17(23)18(24)13-16/h2-8,10,12-13,20-21H,9,11H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306904 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES Cc1cc(on1)[C@@H]1CCCN1C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |r,c:32| Show InChI InChI=1S/C22H21Cl2N5O2/c1-12-10-18(31-27-12)17-4-3-9-28(17)22(30)20-13(2)26-19-7-8-25-29(19)21(20)14-5-6-15(23)16(24)11-14/h5-8,10-11,17,20-21H,3-4,9H2,1-2H3/t17-,20?,21?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211514 (CHEMBL228809 | N-((S)-6-((S)-2-((2,6-dimethylpheny...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1CC(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@H]1CNc1c(C)cccc1C Show InChI InChI=1S/C33H41N3O4S/c1-6-24-12-15-27(16-13-24)41(38,39)35-29-20-33(4,5)40-30-17-14-25(19-28(29)30)32(37)36-18-8-11-26(36)21-34-31-22(2)9-7-10-23(31)3/h7,9-10,12-17,19,26,29,34-35H,6,8,11,18,20-21H2,1-5H3/t26-,29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301460 (7-(3,4-dichlorophenyl)-6-(1,7-dimethyl-1H-benzo[d]...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2cccc(C)c2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C22H19Cl2N5/c1-12-5-4-6-17-20(12)28(3)22(27-17)19-13(2)26-18-9-10-25-29(18)21(19)14-7-8-15(23)16(24)11-14/h4-11,19,21H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211537 ((3S,4R)-4-(4-ethyl-N-neopentylphenylsulfonamido)-3...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N(CC(C)(C)C)[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C33H42N2O5S/c1-7-23-13-16-26(17-14-23)41(38,39)35(22-32(2,3)4)29-27-21-25(15-18-28(27)40-33(5,6)30(29)36)31(37)34-20-19-24-11-9-8-10-12-24/h8-18,21,29-30,36H,7,19-20,22H2,1-6H3,(H,34,37)/t29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254929 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCN(CC1)c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H22Cl2FN5O/c1-15-22(24(33)31-12-10-30(11-13-31)18-5-3-17(27)4-6-18)23(32-21(29-15)8-9-28-32)16-2-7-19(25)20(26)14-16/h2-9,14,22-23H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211535 (CHEMBL387993 | N-((3S,4R)-6-((S)-2-((2,6-dimethylp...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@H]1CNc1c(C)cccc1C Show InChI InChI=1S/C33H41N3O5S/c1-6-23-12-15-26(16-13-23)42(39,40)35-30-27-19-24(14-17-28(27)41-33(4,5)31(30)37)32(38)36-18-8-11-25(36)20-34-29-21(2)9-7-10-22(29)3/h7,9-10,12-17,19,25,30-31,34-35,37H,6,8,11,18,20H2,1-5H3/t25-,30+,31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211525 ((3S,4R)-4-(4-ethyl-N-(pyridin-2-ylmethyl)phenylsul...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N(Cc1ccccn1)[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C34H37N3O5S/c1-4-24-13-16-28(17-14-24)43(40,41)37(23-27-12-8-9-20-35-27)31-29-22-26(15-18-30(29)42-34(2,3)32(31)38)33(39)36-21-19-25-10-6-5-7-11-25/h5-18,20,22,31-32,38H,4,19,21,23H2,1-3H3,(H,36,39)/t31-,32+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50106182 (CHEMBL123085 | N-(3,3-Dimethyl-butyl)-4-(3-phenyl-...) Show SMILES CC(C)(C)CCNC(=O)c1ccc(cc1)-c1nc(no1)-c1ccccc1 Show InChI InChI=1S/C21H23N3O2/c1-21(2,3)13-14-22-19(25)16-9-11-17(12-10-16)20-23-18(24-26-20)15-7-5-4-6-8-15/h4-12H,13-14H2,1-3H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 44: 3764-7 (2001) BindingDB Entry DOI: 10.7270/Q2G1604C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211523 ((3S,4R)-4-(4-ethyl-N-(pyridin-3-ylmethyl)phenylsul...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C34H37N3O5S/c1-4-24-12-15-28(16-13-24)43(40,41)37(23-26-11-8-19-35-22-26)31-29-21-27(14-17-30(29)42-34(2,3)32(31)38)33(39)36-20-18-25-9-6-5-7-10-25/h5-17,19,21-22,31-32,38H,4,18,20,23H2,1-3H3,(H,36,39)/t31-,32+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211542 (CHEMBL230251 | N-((3S,4R)-6-((R)-2-((2,6-dimethylp...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C(=O)N1CCC[C@@H]1CNc1c(C)cccc1C Show InChI InChI=1S/C33H41N3O5S/c1-6-23-12-15-26(16-13-23)42(39,40)35-30-27-19-24(14-17-28(27)41-33(4,5)31(30)37)32(38)36-18-8-11-25(36)20-34-29-21(2)9-7-10-22(29)3/h7,9-10,12-17,19,25,30-31,34-35,37H,6,8,11,18,20H2,1-5H3/t25-,30-,31+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50254966 ((7-(3,5-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCN(CC1)c1ccc(F)cc1)c1cc(Cl)cc(Cl)c1 |t:1| Show InChI InChI=1S/C24H22Cl2FN5O/c1-15-22(24(33)31-10-8-30(9-11-31)20-4-2-19(27)3-5-20)23(32-21(29-15)6-7-28-32)16-12-17(25)14-18(26)13-16/h2-7,12-14,22-23H,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by EP voltage clamp technique				Bioorg Med Chem Lett 18: 6381-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.099 BindingDB Entry DOI: 10.7270/Q2WW7HH7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301454 (7-(3,4-dichlorophenyl)-6-(7-fluoro-1-methyl-1H-ben...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2cccc(F)c2n1C)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H16Cl2FN5/c1-11-18(21-27-16-5-3-4-15(24)20(16)28(21)2)19(29-17(26-11)8-9-25-29)12-6-7-13(22)14(23)10-12/h3-10,18-19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50301453 (7-(3,4-dichlorophenyl)-5-methyl-6-(7-methyl-1H-ben...) Show SMILES CC1=Nc2ccnn2C(C1c1nc2c(C)cccc2[nH]1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H17Cl2N5/c1-11-4-3-5-16-19(11)27-21(26-16)18-12(2)25-17-8-9-24-28(17)20(18)13-6-7-14(22)15(23)10-13/h3-10,18,20H,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 19: 5469-73 (2009) Article DOI: 10.1016/j.bmcl.2009.07.083 BindingDB Entry DOI: 10.7270/Q24M94M6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306893 ((2S)-methyl 1-(7-(3,4-dichlorophenyl)-5-methyl-4,7...) Show SMILES COC(=O)[C@@H]1CCCN1C(=O)C1C(c2ccc(Cl)c(Cl)c2)n2nccc2N=C1C |r,c:29| Show InChI InChI=1S/C20H20Cl2N4O3/c1-11-17(19(27)25-9-3-4-15(25)20(28)29-2)18(26-16(24-11)7-8-23-26)12-5-6-13(21)14(22)10-12/h5-8,10,15,17-18H,3-4,9H2,1-2H3/t15-,17?,18?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50211520 ((3S,4R)-3-hydroxy-2,2-dimethyl-N-phenethyl-4-(2-(t...) Show SMILES CC1(C)Oc2ccc(cc2[C@@H](NS(=O)(=O)c2ccccc2OC(F)(F)F)[C@@H]1O)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C27H27F3N2O6S/c1-26(2)24(33)23(32-39(35,36)22-11-7-6-10-21(22)38-27(28,29)30)19-16-18(12-13-20(19)37-26)25(34)31-15-14-17-8-4-3-5-9-17/h3-13,16,23-24,32-33H,14-15H2,1-2H3,(H,31,34)/t23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 17: 3271-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.020 BindingDB Entry DOI: 10.7270/Q2S75G0V
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50306890 ((7-(3,4-dichlorophenyl)-5-methyl-4,7-dihydropyrazo...) Show SMILES CC1=Nc2ccnn2C(C1C(=O)N1CCCC1c1ccccc1)c1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C24H22Cl2N4O/c1-15-22(24(31)29-13-5-8-20(29)16-6-3-2-4-7-16)23(30-21(28-15)11-12-27-30)17-9-10-18(25)19(26)14-17/h2-4,6-7,9-12,14,20,22-23H,5,8,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells				Bioorg Med Chem Lett 20: 1436-9 (2010) Article DOI: 10.1016/j.bmcl.2009.12.085 BindingDB Entry DOI: 10.7270/Q2MG7PM1
					More data for this Ligand-Target Pair

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