BindingDB PrimarySearch

Found 23 hits with Last Name = 'karasu' and Initial = 'c'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478795 (CHEMBL476908) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2 using NADPH as substrate				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478794 (CHEMBL477942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2 using NADPH as substrate				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478795 (CHEMBL476908) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2 using D,L-glyceraldehyde as substrate				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478794 (CHEMBL477942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2 using D,L-glyceraldehyde as substrate				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM16452 ((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27502 (3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...) Show SMILES O=C1NCCc2c(OCCCCN3CCCCC3)cccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060678 (CHEMBL3394709) Show SMILES OC12N(CCc3cc(Br)ccc13)C(=O)c1ccccc21 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060697 (CHEMBL3394707) Show SMILES COc1cc2CCN3C(=O)c4ccccc4C3(O)c2cc1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060696 (CHEMBL3394712) Show SMILES COc1ccc2C3CCCC(=O)N3CCc2c1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	565	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060762 (CHEMBL3394705) Show SMILES COc1cc2CCN3C(=O)c4ccccc4C3(O)c2cc1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	865	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060677 (CHEMBL3394710) Show SMILES Cc1ccc2c(CCN3C(=O)c4ccccc4C23O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	977	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060701 (CHEMBL3394706) Show SMILES COc1ccc2c(CCN3C(=O)c4ccccc4C23O)c1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	983	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060698 (CHEMBL3394708) Show SMILES COc1ccc2c(CCN3C(=O)c4ccccc4C23O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060676 (CHEMBL3394704) Show SMILES COc1ccc(OC)c2c1CCN1C(=O)c3ccccc3C21O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060702 (CHEMBL3394711) Show SMILES COc1cc2CCN3C(CCC3=O)c2c(OC)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50060743 (CHEMBL3394703) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pondicherry University Curated by ChEMBL					Assay Description Inhibition of PARP1 (unknown origin) in presence of NAD+ by homogenous fluorescence plate assay				Bioorg Med Chem 23: 488-98 (2015) Article DOI: 10.1016/j.bmc.2014.12.017 BindingDB Entry DOI: 10.7270/Q2BV7J9N
Pondicherry University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478795 (CHEMBL476908) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478794 (CHEMBL477942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478791 (CHEMBL477933) Show SMILES CN1CCc2[nH]c3ccc(CC([O-])=O)cc3c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478793 (CHEMBL479175) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478796 (CHEMBL479174) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.81E+5	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478797 (DEHYDROSTOBADINE) Show SMILES CN1CCc2[nH]c3ccc(C)cc3c2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rattus norvegicus)	BDBM50478792 (stobadine) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Wistar rat lens aldose reductase 2				Bioorg Med Chem 16: 4908-20 (2008) Article DOI: 10.1016/j.bmc.2008.03.039 BindingDB Entry DOI: 10.7270/Q2HQ42PT
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair