Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'kosakai' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (RAT)	BDBM50013027 (CHEMBL262655 | Sodium; 3-[4-(4-chloro-benzenesulfo...) Show SMILES CC(C)c1ccc2c(CCCCNS(=O)(=O)c3ccc(Cl)cc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C23H26ClNO5S2/c1-16(2)17-6-12-21-18(15-23(32(28,29)30)22(21)13-7-17)5-3-4-14-25-31(26,27)20-10-8-19(24)9-11-20/h6-13,15-16,25H,3-5,14H2,1-2H3,(H,28,29,30)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381555 (CHEMBL2018097) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2cc3ccccc3s2)c1 |r| Show InChI InChI=1S/C21H21ClO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381554 (CHEMBL2018096) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(F)c(Cc2cc3ccccc3s2)c1 |r| Show InChI InChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436116 (CHEMBL2397452) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2cc3cccccc3c2)c1 |r| Show InChI InChI=1S/C23H23ClO5/c24-18-7-6-16(23-22(28)21(27)20(26)19(12-25)29-23)11-17(18)10-13-8-14-4-2-1-3-5-15(14)9-13/h1-9,11,19-23,25-28H,10,12H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436115 (CHEMBL2397450) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3cccccc3c2)ccc1O |r| Show InChI InChI=1S/C23H24O6/c24-12-19-20(26)21(27)22(28)23(29-19)17-11-13(6-7-18(17)25)8-14-9-15-4-2-1-3-5-16(15)10-14/h1-7,9-11,19-28H,8,12H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381548 (CHEMBL2018090) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3ccccc3s2)ccc1O |r| Show InChI InChI=1S/C21H22O6S/c22-10-16-18(24)19(25)20(26)21(27-16)14-8-11(5-6-15(14)23)7-13-9-12-3-1-2-4-17(12)28-13/h1-6,8-9,16,18-26H,7,10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381537 (CHEMBL2017954) Show SMILES CCc1ccc(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H26O5/c1-2-13-6-8-14(9-7-13)10-15-4-3-5-16(11-15)21-20(25)19(24)18(23)17(12-22)26-21/h3-9,11,17-25H,2,10,12H2,1H3/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381549 (CHEMBL2018091) Show SMILES COc1ccc(Cc2cc3ccccc3s2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H24O6S/c1-27-16-7-6-12(8-14-10-13-4-2-3-5-18(13)29-14)9-15(16)22-21(26)20(25)19(24)17(11-23)28-22/h2-7,9-10,17,19-26H,8,11H2,1H3/t17-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381553 (CHEMBL2018095) Show SMILES COc1ccc(cc1Cc1cc2ccccc2s1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H24O6S/c1-27-16-7-6-13(22-21(26)20(25)19(24)17(11-23)28-22)8-14(16)10-15-9-12-4-2-3-5-18(12)29-15/h2-9,17,19-26H,10-11H2,1H3/t17-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436114 (CHEMBL2397451) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(F)c(Cc2cc3cccccc3c2)c1 |r| Show InChI InChI=1S/C23H23FO5/c24-18-7-6-16(23-22(28)21(27)20(26)19(12-25)29-23)11-17(18)10-13-8-14-4-2-1-3-5-15(14)9-13/h1-9,11,19-23,25-28H,10,12H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436113 (CHEMBL2397449) Show SMILES COc1ccc(Cc2cc3cccccc3c2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C24H26O6/c1-29-19-8-7-14(9-15-10-16-5-3-2-4-6-17(16)11-15)12-18(19)24-23(28)22(27)21(26)20(13-25)30-24/h2-8,10-12,20-28H,9,13H2,1H3/t20-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436112 (CHEMBL2397453) Show SMILES COc1ccc(cc1Cc1cc2cccccc2c1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C24H26O6/c1-29-19-8-7-17(24-23(28)22(27)21(26)20(13-25)30-24)12-18(19)11-14-9-15-5-3-2-4-6-16(15)10-14/h2-10,12,20-28H,11,13H2,1H3/t20-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436111 (CHEMBL2397442) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2cc3cccccc3c2)c1 |r| Show InChI InChI=1S/C23H24O5/c24-13-19-20(25)21(26)22(27)23(28-19)18-8-4-5-14(10-18)9-15-11-16-6-2-1-3-7-17(16)12-15/h1-8,10-12,19-27H,9,13H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381544 (CHEMBL2018084) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2cc3ccccc3s2)c1 |r| Show InChI InChI=1S/C21H22O5S/c22-11-16-18(23)19(24)20(25)21(26-16)14-6-3-4-12(8-14)9-15-10-13-5-1-2-7-17(13)27-15/h1-8,10,16,18-25H,9,11H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436110 (CHEMBL2397447) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3cccccc3c2)ccc1F |r| Show InChI InChI=1S/C23H23FO5/c24-18-7-6-13(8-14-9-15-4-2-1-3-5-16(15)10-14)11-17(18)23-22(28)21(27)20(26)19(12-25)29-23/h1-7,9-11,19-23,25-28H,8,12H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381550 (CHEMBL2018092) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3ccccc3s2)ccc1F |r| Show InChI InChI=1S/C21H21FO5S/c22-15-6-5-11(7-13-9-12-3-1-2-4-17(12)28-13)8-14(15)21-20(26)19(25)18(24)16(10-23)27-21/h1-6,8-9,16,18-21,23-26H,7,10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436109 (CHEMBL2397448) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3cccccc3c2)ccc1Cl |r| Show InChI InChI=1S/C23H23ClO5/c24-18-7-6-13(8-14-9-15-4-2-1-3-5-16(15)10-14)11-17(18)23-22(28)21(27)20(26)19(12-25)29-23/h1-7,9-11,19-23,25-28H,8,12H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381539 (CHEMBL2017956) Show SMILES CCc1ccc(Cc2cc(c[nH]2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C19H25NO5/c1-2-11-3-5-12(6-4-11)7-14-8-13(9-20-14)19-18(24)17(23)16(22)15(10-21)25-19/h3-6,8-9,15-24H,2,7,10H2,1H3/t15-,16-,17+,18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381552 (CHEMBL2018094) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(O)c(Cc2cc3ccccc3s2)c1 |r| Show InChI InChI=1S/C21H22O6S/c22-10-16-18(24)19(25)20(26)21(27-16)12-5-6-15(23)13(7-12)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381551 (CHEMBL2018093) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2cc3ccccc3s2)ccc1Cl |r| Show InChI InChI=1S/C21H21ClO5S/c22-15-6-5-11(7-13-9-12-3-1-2-4-17(12)28-13)8-14(15)21-20(26)19(25)18(24)16(10-23)27-21/h1-6,8-9,16,18-21,23-26H,7,10H2/t16-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436108 (CHEMBL2397441) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2ccc3cccc3cc2)c1 |r| Show InChI InChI=1S/C23H24O5/c24-13-19-20(25)21(26)22(27)23(28-19)18-6-1-3-15(12-18)11-14-7-9-16-4-2-5-17(16)10-8-14/h1-10,12,19-27H,11,13H2/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381538 (CHEMBL2017955) Show SMILES COc1ccc(Cc2cc(cs2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C18H22O6S/c1-23-12-4-2-10(3-5-12)6-13-7-11(9-25-13)18-17(22)16(21)15(20)14(8-19)24-18/h2-5,7,9,14-22H,6,8H2,1H3/t14-,15-,16+,17-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282138 (CHEMBL298462 | Sodium; 3-[4-(4-chloro-phenylsulfam...) Show SMILES CC(C)c1ccc2c(CCCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C23H26ClNO5S2/c1-16(2)17-6-12-21-18(15-23(32(28,29)30)22(21)13-7-17)5-3-4-14-31(26,27)25-20-10-8-19(24)9-11-20/h6-13,15-16,25H,3-5,14H2,1-2H3,(H,28,29,30)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381540 (CHEMBL2018080) Show SMILES CCc1ccc(Cc2cccc(n2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H25NO5/c1-2-12-6-8-13(9-7-12)10-14-4-3-5-15(21-14)20-19(25)18(24)17(23)16(11-22)26-20/h3-9,16-20,22-25H,2,10-11H2,1H3/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381546 (CHEMBL2018087) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2nc3ccccc3s2)c1 |r| Show InChI InChI=1S/C20H21NO5S/c22-10-14-17(23)18(24)19(25)20(26-14)12-5-3-4-11(8-12)9-16-21-13-6-1-2-7-15(13)27-16/h1-8,14,17-20,22-25H,9-10H2/t14-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381545 (CHEMBL2018085) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2cc3ccccc3o2)c1 |r| Show InChI InChI=1S/C21H22O6/c22-11-17-18(23)19(24)20(25)21(27-17)14-6-3-4-12(8-14)9-15-10-13-5-1-2-7-16(13)26-15/h1-8,10,17-25H,9,11H2/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	675	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282141 (CHEMBL46338 | Sodium; 3-[5-(4-chloro-phenylsulfamo...) Show SMILES CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C24H28ClNO5S2/c1-17(2)18-7-13-22-19(16-24(33(29,30)31)23(22)14-8-18)6-4-3-5-15-32(27,28)26-21-11-9-20(25)10-12-21/h7-14,16-17,26H,3-6,15H2,1-2H3,(H,29,30,31)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282135 (CHEMBL430569 | Sodium; 3-[3-(4-chloro-phenylsulfam...) Show SMILES CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C22H24ClNO5S2/c1-15(2)16-5-11-20-17(14-22(31(27,28)29)21(20)12-6-16)4-3-13-30(25,26)24-19-9-7-18(23)8-10-19/h5-12,14-15,24H,3-4,13H2,1-2H3,(H,27,28,29)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436120 (CHEMBL2397445) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2cc3cccccc3c2Cc2ccccc2)c1 |r| Show InChI InChI=1S/C30H30O5/c31-18-26-27(32)28(33)29(34)30(35-26)22-12-7-10-20(14-22)15-23-17-21-11-5-2-6-13-24(21)25(23)16-19-8-3-1-4-9-19/h1-14,17,26-34H,15-16,18H2/t26-,27-,28+,29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282152 (CHEMBL47605 | Sodium; 6-isopropyl-3-(5-phenylsulfa...) Show SMILES CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccccc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C24H29NO5S2/c1-18(2)19-12-14-22-20(17-24(32(28,29)30)23(22)15-13-19)9-5-4-8-16-31(26,27)25-21-10-6-3-7-11-21/h3,6-7,10-15,17-18,25H,4-5,8-9,16H2,1-2H3,(H,28,29,30)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282146 (CHEMBL48013 | Sodium; 6-isopropyl-3-(4-phenylsulfa...) Show SMILES CC(C)c1ccc2c(CCCCS(=O)(=O)Nc3ccccc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C23H27NO5S2/c1-17(2)18-11-13-21-19(16-23(31(27,28)29)22(21)14-12-18)8-6-7-15-30(25,26)24-20-9-4-3-5-10-20/h3-5,9-14,16-17,24H,6-8,15H2,1-2H3,(H,27,28,29)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50002765 (BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...) Show SMILES OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C16H17NO5S/c18-16(19)12-22-14-8-6-13(7-9-14)10-11-17-23(20,21)15-4-2-1-3-5-15/h1-9,17H,10-12H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282136 (6-Isopropyl-3-(5-phenylsulfamoyl-pentyl)-azulene-1...) Show SMILES CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C25H29NO4S/c1-18(2)19-12-14-22-20(17-24(25(27)28)23(22)15-13-19)9-5-4-8-16-31(29,30)26-21-10-6-3-7-11-21/h3,6-7,10-15,17-18,26H,4-5,8-9,16H2,1-2H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282156 (3-[5-(4-Chloro-phenylsulfamoyl)-pentyl]-6-isopropy...) Show SMILES CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C25H28ClNO4S/c1-17(2)18-7-13-22-19(16-24(25(28)29)23(22)14-8-18)6-4-3-5-15-32(30,31)27-21-11-9-20(26)10-12-21/h7-14,16-17,27H,3-6,15H2,1-2H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381547 (CHEMBL2018088) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2nc3ccccc3o2)c1 |r| Show InChI InChI=1S/C20H21NO6/c22-10-15-17(23)18(24)19(25)20(27-15)12-5-3-4-11(8-12)9-16-21-13-6-1-2-7-14(13)26-16/h1-8,15,17-20,22-25H,9-10H2/t15-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282139 (3-[4-(4-Chloro-phenylsulfamoyl)-butyl]-6-isopropyl...) Show SMILES CC(C)c1ccc2c(CCCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C24H26ClNO4S/c1-16(2)17-6-12-21-18(15-23(24(27)28)22(21)13-7-17)5-3-4-14-31(29,30)26-20-10-8-19(25)9-11-20/h6-13,15-16,26H,3-5,14H2,1-2H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381541 (CHEMBL2018081) Show SMILES CCc1ccc(Cc2cncc(n2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C19H24N2O5/c1-2-11-3-5-12(6-4-11)7-13-8-20-9-14(21-13)19-18(25)17(24)16(23)15(10-22)26-19/h3-6,8-9,15-19,22-25H,2,7,10H2,1H3/t15-,16-,17+,18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436119 (CHEMBL2397444) Show SMILES CCc1c(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2cccccc12 |r| Show InChI InChI=1S/C25H28O5/c1-2-19-18(13-16-8-4-3-5-10-20(16)19)12-15-7-6-9-17(11-15)25-24(29)23(28)22(27)21(14-26)30-25/h3-11,13,21-29H,2,12,14H2,1H3/t21-,22-,23+,24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50381556 (CHEMBL2018086) Show SMILES Cn1c(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2ccccc12 |r| Show InChI InChI=1S/C22H25NO5/c1-23-16(11-14-6-2-3-8-17(14)23)10-13-5-4-7-15(9-13)22-21(27)20(26)19(25)18(12-24)28-22/h2-9,11,18-22,24-27H,10,12H2,1H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting				Bioorg Med Chem 20: 3263-79 (2012) Article DOI: 10.1016/j.bmc.2012.03.051 BindingDB Entry DOI: 10.7270/Q2W66MSS
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282133 (CHEMBL47510 | Sodium; 6-isopropyl-3-(3-phenylsulfa...) Show SMILES CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccccc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C22H25NO5S2/c1-16(2)17-10-12-20-18(15-22(30(26,27)28)21(20)13-11-17)7-6-14-29(24,25)23-19-8-4-3-5-9-19/h3-5,8-13,15-16,23H,6-7,14H2,1-2H3,(H,26,27,28)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282154 (6-Isopropyl-3-(4-phenylsulfamoyl-butyl)-azulene-1-...) Show SMILES CC(C)c1ccc2c(CCCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C24H27NO4S/c1-17(2)18-11-13-21-19(16-23(24(26)27)22(21)14-12-18)8-6-7-15-30(28,29)25-20-9-4-3-5-10-20/h3-5,9-14,16-17,25H,6-8,15H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282147 (3-[3-(4-Chloro-phenylsulfamoyl)-propyl]-6-isopropy...) Show SMILES CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C23H24ClNO4S/c1-15(2)16-5-11-20-17(14-22(23(26)27)21(20)12-6-16)4-3-13-30(28,29)25-19-9-7-18(24)8-10-19/h5-12,14-15,25H,3-4,13H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282134 (6-Isopropyl-3-(3-phenylsulfamoyl-propyl)-azulene-1...) Show SMILES CC(C)c1ccc2c(CCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C23H25NO4S/c1-16(2)17-10-12-20-18(15-22(23(25)26)21(20)13-11-17)7-6-14-29(27,28)24-19-8-4-3-5-9-19/h3-5,8-13,15-16,24H,6-7,14H2,1-2H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436118 (CHEMBL2397446) Show SMILES CC(=O)c1c(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2cccccc12 |r| Show InChI InChI=1S/C25H26O6/c1-14(27)21-18(12-16-7-3-2-4-9-19(16)21)11-15-6-5-8-17(10-15)25-24(30)23(29)22(28)20(13-26)31-25/h2-10,12,20,22-26,28-30H,11,13H2,1H3/t20-,22-,23+,24-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282144 (3-[4-(4-Chloro-benzenesulfonylamino)-4-oxo-butyl]-...) Show SMILES CC(C)c1ccc2c(CCCC(=O)NS(=O)(=O)c3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C24H24ClNO5S/c1-15(2)16-6-12-20-17(14-22(24(28)29)21(20)13-7-16)4-3-5-23(27)26-32(30,31)19-10-8-18(25)9-11-19/h6-15H,3-5H2,1-2H3,(H,26,27)(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50436117 (CHEMBL2397443) Show SMILES Cc1cc(Cc2cccc(c2)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2cccccc12 |r| Show InChI InChI=1S/C24H26O5/c1-14-10-17(19-9-4-2-3-8-18(14)19)12-15-6-5-7-16(11-15)24-23(28)22(27)21(26)20(13-25)29-24/h2-11,20-28H,12-13H2,1H3/t20-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation				Bioorg Med Chem 21: 3934-48 (2013) Article DOI: 10.1016/j.bmc.2013.03.067 BindingDB Entry DOI: 10.7270/Q2ZC848C
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282148 (CHEMBL297989 | Sodium; 3-[4-(4-chloro-benzenesulfo...) Show SMILES CC(C)c1ccc2c(CCCC(=O)NS(=O)(=O)c3ccc(Cl)cc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C23H24ClNO6S2/c1-15(2)16-6-12-20-17(14-22(33(29,30)31)21(20)13-7-16)4-3-5-23(26)25-32(27,28)19-10-8-18(24)9-11-19/h6-15H,3-5H2,1-2H3,(H,25,26)(H,29,30,31)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282140 (CHEMBL45623 | Sodium; 3-(4-benzenesulfonylamino-4-...) Show SMILES CC(C)c1ccc2c(CCCC(=O)NS(=O)(=O)c3ccccc3)cc(c2cc1)S([O-])(=O)=O Show InChI InChI=1S/C23H25NO6S2/c1-16(2)17-11-13-20-18(15-22(32(28,29)30)21(20)14-12-17)7-6-10-23(25)24-31(26,27)19-8-4-3-5-9-19/h3-5,8-9,11-16H,6-7,10H2,1-2H3,(H,24,25)(H,28,29,30)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282143 (3-{[2-(4-Chloro-benzoylamino)-acetylamino]-methyl}...) Show SMILES CC(C)c1ccc2c(CNC(=O)CNC(=O)c3ccc(Cl)cc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C24H23ClN2O4/c1-14(2)15-5-9-19-17(11-21(24(30)31)20(19)10-6-15)12-26-22(28)13-27-23(29)16-3-7-18(25)8-4-16/h3-11,14H,12-13H2,1-2H3,(H,26,28)(H,27,29)(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (RAT)	BDBM50282142 (3-[(2-Benzoylamino-acetylamino)-methyl]-6-isopropy...) Show SMILES CC(C)c1ccc2c(CNC(=O)CNC(=O)c3ccccc3)cc(C(O)=O)c2cc1 Show InChI InChI=1S/C24H24N2O4/c1-15(2)16-8-10-19-18(12-21(24(29)30)20(19)11-9-16)13-25-22(27)14-26-23(28)17-6-4-3-5-7-17/h3-12,15H,13-14H2,1-2H3,(H,25,27)(H,26,28)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for antagonistic activity on isolated rat thoracic aorta (TXA2 receptor) precontracted by U-46619 (3 x 10 e-8 M)				Bioorg Med Chem Lett 3: 1687-1692 (1993) Article DOI: 10.1016/S0960-894X(00)80043-8 BindingDB Entry DOI: 10.7270/Q2H70FQG
					More data for this Ligand-Target Pair

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