Compile Data Set for Download or QSAR

Found 1343 hits with Last Name = 'kwon' and Initial = 'dy'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50321104 (CHEMBL1163804 | DFGYVAE) Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r| Show InChI InChI=1S/C37H49N7O13/c1-19(2)31(36(55)40-20(3)32(51)42-25(37(56)57)13-14-29(47)48)44-35(54)27(16-22-9-11-23(45)12-10-22)41-28(46)18-39-34(53)26(15-21-7-5-4-6-8-21)43-33(52)24(38)17-30(49)50/h4-12,19-20,24-27,31,45H,13-18,38H2,1-3H3,(H,39,53)(H,40,55)(H,41,46)(H,42,51)(H,43,52)(H,44,54)(H,47,48)(H,49,50)(H,56,57)/t20-,24-,25-,26-,27-,31-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of the Chemistry of Plant Substances Curated by ChEMBL					Assay Description Competitive inhibition of HMG-CoA reductase by Dixon plot analysis				Bioorg Med Chem 18: 4300-9 (2010) Article DOI: 10.1016/j.bmc.2010.04.090 BindingDB Entry DOI: 10.7270/Q2VM4CFG
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50321100 (CHEMBL1164546 | GF(4-fluro)PTGG) Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CN)C(=O)NCC(=O)NCC(O)=O |r| Show InChI InChI=1S/C24H33FN6O8/c1-13(32)21(23(38)28-11-19(34)27-12-20(35)36)30-22(37)17-3-2-8-31(17)24(39)16(29-18(33)10-26)9-14-4-6-15(25)7-5-14/h4-7,13,16-17,21,32H,2-3,8-12,26H2,1H3,(H,27,34)(H,28,38)(H,29,33)(H,30,37)(H,35,36)/t13-,16+,17+,21+/m1/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of the Chemistry of Plant Substances Curated by ChEMBL					Assay Description Competitive inhibition of HMG-CoA reductase by Dixon plot analysis				Bioorg Med Chem 18: 4300-9 (2010) Article DOI: 10.1016/j.bmc.2010.04.090 BindingDB Entry DOI: 10.7270/Q2VM4CFG
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604246 (Preparation of (S)—N-(4-carbamimidoylbenzyl)-1-((2...) Show SMILES CN1CC[C@@H](C[C@@H]1C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604249 (Preparation of (2R,4S)—N—((S)-1-((4-carbamimidoylb...) Show SMILES CCN1CC[C@@H](C[C@@H]1C(=O)N[C@@H](C)C(=O)NCc1ccc(cc1)C(N)=N)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604250 (Preparation of (2R,4S)-4-(3-(1H-pyrazol-1-yl)pheny...) Show SMILES CCN1CC[C@@H](C[C@@H]1C(=O)N[C@@H](C)C(=O)NCc1cc(Cl)ccc1-n1cnnn1)c1cccc(c1)-n1cccn1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604251 (Preparation of (2R,4S)—N—((S)-1-(((5-((Z)—N-hydrox...) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](CCN1)c1ccccc1)C(=O)NCc1ccc(s1)C(\N)=N\O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595064 (US11584714, Compound 1092) Show SMILES C[C@H](NC(=O)[C@H](N)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595064 (US11584714, Compound 1092) Show SMILES C[C@H](NC(=O)[C@H](N)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595064 (US11584714, Compound 1092) Show SMILES C[C@H](NC(=O)[C@H](N)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595401 (US11584714, Compound 1489) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595402 (US11584714, Compound 1490) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cnc2[nH]cc(Cl)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595402 (US11584714, Compound 1490) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cnc2[nH]cc(Cl)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595403 (US11584714, Compound 1491) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2c(N)nccc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595403 (US11584714, Compound 1491) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2c(N)nccc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595404 (US11584714, Compound 1492) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2nc(N)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595404 (US11584714, Compound 1492) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2nc(N)[nH]c2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM595404 (US11584714, Compound 1492) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2nc(N)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595406 (US11584714, Compound 1494) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccc(F)c(Cl)c2)CN1)C(=O)NCc1cc2cnccc2[nH]1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595406 (US11584714, Compound 1494) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccc(F)c(Cl)c2)CN1)C(=O)NCc1cc2cnccc2[nH]1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595408 (US11584714, Compound 1496) Show SMILES CCN1CC[C@@H](C[C@@H]1C(=O)N[C@@H](C)C(=O)NCc1ccc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595409 (US11584714, Compound 1497) Show SMILES C[C@H](N(C)C(=O)[C@H]1C[C@H](Cc2ccc(Br)cc2)CN1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604240 (Preparation of (2R,4S)—N—((S)-1-((4-((Z)—N′-...) Show SMILES CC(C)[C@H](N)C(=O)O\N=C(/N)c1ccc(CNC(=O)[C@H](C)NC(=O)[C@H]2C[C@H](CCN2)c2ccccc2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604241 (Preparation of (2R,4S)-2-(((S)-1-((4-carbamimidoyl...) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](CC[N+]1(C)C)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604242 (Preparation of ethyl 3-((2R,4S)-2-(((S)-1-((4-carb...) Show SMILES CCOC(=O)CCN1CC[C@@H](C[C@@H]1C(=O)N[C@@H](C)C(=O)NCc1ccc(cc1)C(N)=N)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604243 (Preparation of 3-((2R,4S)-2-(((S)-1-((4-carbamimid...) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](CCN1CCC(O)=O)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604244 (US11661418, Compound I-15) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](CCN1CCP(O)(O)=O)c1ccccc1)C(=O)NCc1cc2cnccc2[nH]1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM604245 (US11661418, Compound I-16) Show SMILES CN1CC[C@@H](C[C@@H]1C(=O)N1CC[C@H]1C(=O)NCc1ccc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2P2733R
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595388 (US11584714, Compound 1476) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595388 (US11584714, Compound 1476) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(C)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595389 (US11584714, Compound 1477) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(Cl)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595389 (US11584714, Compound 1477) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cccc(Cl)c2)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595390 (US11584714, Compound 1478) Show SMILES COc1cc2ccccc2cc1C[C@@H]1CN[C@H](C1)C(=O)N[C@@H](C)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595390 (US11584714, Compound 1478) Show SMILES COc1cc2ccccc2cc1C[C@@H]1CN[C@H](C1)C(=O)N[C@@H](C)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595391 (US11584714, Compound 1479) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccc(C)c3ccccc23)CN1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595392 (US11584714, Compound 1480) Show SMILES C[C@H](NC(=O)[C@H]1CC(Cc2ccc(F)cc2)(Cc2ccc(F)cc2)CN1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595393 (US11584714, Compound 1481) Show SMILES C[C@H](NC(=O)[C@H]1C[C@@H](CN1)C1(CC1)c1ccccc1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595393 (US11584714, Compound 1481) Show SMILES C[C@H](NC(=O)[C@H]1C[C@@H](CN1)C1(CC1)c1ccccc1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595394 (US11584714, Compound 1482) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccccc2Br)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595394 (US11584714, Compound 1482) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccccc2Br)CN1)C(=O)NCc1cnc2n(C)cc(Cl)c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595395 (US11584714, Compound 1483) Show SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2cc(Br)c(Cl)s2)CN1)C(=O)NCc1ccc(N)nc1C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595397 (US11584714, Compound 1485) Show SMILES C[C@H](NC(=O)[C@H]1C[C@@H](CCN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595397 (US11584714, Compound 1485) Show SMILES C[C@H](NC(=O)[C@H]1C[C@@H](CCN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595398 (US11584714, Compound 1486) Show SMILES C[C@H](NC(=O)[C@@H]1C[C@H](CCN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM50067797 (CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...) Show SMILES Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCCc2ccccc2)c1=O Show InChI InChI=1S/C22H26N6O2/c1-15-12-26-21(24-11-10-17-6-4-3-5-7-17)22(30)28(15)14-20(29)25-13-18-8-9-19(23)27-16(18)2/h3-9,12H,10-11,13-14H2,1-2H3,(H2,23,27)(H,24,26)(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
thrombin (Homo sapiens (Human))	BDBM50067797 (CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...) Show SMILES Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCCc2ccccc2)c1=O Show InChI InChI=1S/C22H26N6O2/c1-15-12-26-21(24-11-10-17-6-4-3-5-7-17)22(30)28(15)14-20(29)25-13-18-8-9-19(23)27-16(18)2/h3-9,12H,10-11,13-14H2,1-2H3,(H2,23,27)(H,24,26)(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595401 (US11584714, Compound 1489) Show SMILES Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595035 (US11584714, Compound 1063 | US11584714, Compound 1...) Show SMILES C[C@H](NC(=O)C1CC(CCN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595039 (US11584714, Compound 1067 | US11584714, Compound 1...) Show SMILES C[C@H](NC(=O)C1CCC(CN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Mouse)	BDBM595039 (US11584714, Compound 1067 | US11584714, Compound 1...) Show SMILES C[C@H](NC(=O)C1CCC(CN1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair
Mannan-binding lectin serine protease 2 (Homo sapiens)	BDBM595041 (US11584714, Compound 1069) Show SMILES N[C@H](CCCc1ccccc1)C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SRT
					More data for this Ligand-Target Pair

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