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Compile Data Set for Download or QSAR

Found 341 hits with Last Name = 'larson' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 3


(Mus musculus)
BDBM50574259
PNG
(CHEMBL4865888)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574231
PNG
(CHEMBL4850510)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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1.60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574246
PNG
(CHEMBL4852297)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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2n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574230
PNG
(CHEMBL4851302)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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2.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574244
PNG
(CHEMBL4852476)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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2.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574236
PNG
(CHEMBL4848948)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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3.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574238
PNG
(CHEMBL4848870)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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3.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574229
PNG
(CHEMBL4848905)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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3.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574253
PNG
(CHEMBL4863587)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574242
PNG
(CHEMBL4859395)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574245
PNG
(CHEMBL4861645)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574240
PNG
(CHEMBL4872732)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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6.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574239
PNG
(CHEMBL4866219)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574259
PNG
(CHEMBL4865888)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574243
PNG
(CHEMBL4863637)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574228
PNG
(CHEMBL4870667)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(N)=O |r|
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20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574235
PNG
(CHEMBL4866496)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(N)=O |r|
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25n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574262
PNG
(CHEMBL4876953)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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25n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574236
PNG
(CHEMBL4848948)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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32n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574238
PNG
(CHEMBL4848870)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574246
PNG
(CHEMBL4852297)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574244
PNG
(CHEMBL4852476)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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63n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574230
PNG
(CHEMBL4851302)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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79n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574231
PNG
(CHEMBL4850510)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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100n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574261
PNG
(CHEMBL4878799)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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100n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549822
PNG
(CHEMBL4795352)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O |r|
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125n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574245
PNG
(CHEMBL4861645)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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130n/an/an/an/an/an/an/an/a


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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574229
PNG
(CHEMBL4848905)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574253
PNG
(CHEMBL4863587)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549823
PNG
(CHEMBL4748317)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574239
PNG
(CHEMBL4866219)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574248
PNG
(CHEMBL4846677)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574264
PNG
(CHEMBL4858442)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574265
PNG
(CHEMBL4877266)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574258
PNG
(CHEMBL4868611)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549819
PNG
(CHEMBL4791112)
Show SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r|
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250n/an/an/an/an/an/an/an/a


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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574237
PNG
(CHEMBL4860080)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574255
PNG
(CHEMBL4862028)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549814
PNG
(CHEMBL4794484)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549815
PNG
(CHEMBL4754987)
Show SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50266756
PNG
(CHEMBL4068777)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50549818
PNG
(CHEMBL4783292)
Show SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O |r|
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400n/an/an/an/an/an/an/an/a


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Assay Description
Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00561
BindingDB Entry DOI: 10.7270/Q2N301KK
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574237
PNG
(CHEMBL4860080)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574241
PNG
(CHEMBL4860703)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574254
PNG
(CHEMBL4872238)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574235
PNG
(CHEMBL4866496)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCCN)C(N)=O |r|
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630n/an/an/an/an/an/an/an/a


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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574243
PNG
(CHEMBL4863637)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](CCCCN)C(N)=O |r|
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630n/an/an/an/an/an/an/an/a


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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50266756
PNG
(CHEMBL4068777)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1
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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574264
PNG
(CHEMBL4858442)
Show SMILES CC(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Mus musculus)
BDBM50574242
PNG
(CHEMBL4859395)
Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
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Assay Description
Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01417
BindingDB Entry DOI: 10.7270/Q2RR231G
More data for this
Ligand-Target Pair
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