Found 1774 hits with Last Name = 'lewis' and Initial = 'i' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474224
(CHEMBL3349523)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C57H70N12O9S2/c1-32(2)49-57(78)68-48(55(76)64-44(50(60)71)26-35-28-61-41-16-8-6-14-38(35)41)31-80-79-30-47(67-51(72)40(59)24-33-12-4-3-5-13-33)56(77)65-45(25-34-19-21-37(70)22-20-34)53(74)66-46(27-36-29-62-42-17-9-7-15-39(36)42)54(75)63-43(52(73)69-49)18-10-11-23-58/h3-9,12-17,19-22,28-29,32,40,43-49,61-62,70H,10-11,18,23-27,30-31,58-59H2,1-2H3,(H2,60,71)(H,63,75)(H,64,76)(H,65,77)(H,66,74)(H,67,72)(H,68,78)(H,69,73)/t40-,43+,44+,45+,46-,47+,48+,49+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474230
(CHEMBL3349516)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C76H105N19O17S2/c1-41(79)65(101)83-38-61(99)85-59-40-114-113-39-58(64(81)100)93-66(102)42(2)84-75(111)62(43(3)96)95-73(109)55(34-47-24-12-7-13-25-47)92-76(112)63(44(4)97)94-68(104)52(29-17-19-31-78)86-71(107)56(35-48-37-82-50-27-15-14-26-49(48)50)90-70(106)54(33-46-22-10-6-11-23-46)88-69(105)53(32-45-20-8-5-9-21-45)89-72(108)57(36-60(80)98)91-67(103)51(87-74(59)110)28-16-18-30-77/h5-15,20-27,37,41-44,51-59,62-63,82,96-97H,16-19,28-36,38-40,77-79H2,1-4H3,(H2,80,98)(H2,81,100)(H,83,101)(H,84,111)(H,85,99)(H,86,107)(H,87,110)(H,88,105)(H,89,108)(H,90,106)(H,91,103)(H,92,112)(H,93,102)(H,94,104)(H,95,109)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50051568
((3S,6S,9S,12R,15S,18S)-9-(4-Amino-butyl)-3-benzyl-...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O Show InChI InChI=1S/C44H56N8O7/c1-26(2)38-43(58)50-37(23-28-12-6-5-7-13-28)44(59)52(4)27(3)39(54)48-35(22-29-17-19-31(53)20-18-29)41(56)49-36(24-30-25-46-33-15-9-8-14-32(30)33)42(57)47-34(40(55)51-38)16-10-11-21-45/h5-9,12-15,17-20,25-27,34-38,46,53H,10-11,16,21-24,45H2,1-4H3,(H,47,57)(H,48,54)(H,49,56)(H,50,58)(H,51,55)/t27-,34-,35-,36+,37-,38-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474230
(CHEMBL3349516)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C76H105N19O17S2/c1-41(79)65(101)83-38-61(99)85-59-40-114-113-39-58(64(81)100)93-66(102)42(2)84-75(111)62(43(3)96)95-73(109)55(34-47-24-12-7-13-25-47)92-76(112)63(44(4)97)94-68(104)52(29-17-19-31-78)86-71(107)56(35-48-37-82-50-27-15-14-26-49(48)50)90-70(106)54(33-46-22-10-6-11-23-46)88-69(105)53(32-45-20-8-5-9-21-45)89-72(108)57(36-60(80)98)91-67(103)51(87-74(59)110)28-16-18-30-77/h5-15,20-27,37,41-44,51-59,62-63,82,96-97H,16-19,28-36,38-40,77-79H2,1-4H3,(H2,80,98)(H2,81,100)(H,83,101)(H,84,111)(H,85,99)(H,86,107)(H,87,110)(H,88,105)(H,89,108)(H,90,106)(H,91,103)(H,92,112)(H,93,102)(H,94,104)(H,95,109)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474235
(CHEMBL3349606)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN(C)C Show InChI InChI=1S/C61H72N10O9/c1-70(2)31-30-63-61(78)80-46-36-54-59(76)68-51(32-40-16-6-3-7-17-40)56(73)67-52(35-44-37-64-48-23-13-12-22-47(44)48)58(75)65-49(24-14-15-29-62)55(72)66-50(33-42-25-27-45(28-26-42)79-39-43-20-10-5-11-21-43)57(74)69-53(60(77)71(54)38-46)34-41-18-8-4-9-19-41/h3-13,16-23,25-28,37,46,49-54,64H,14-15,24,29-36,38-39,62H2,1-2H3,(H,63,78)(H,65,75)(H,66,72)(H,67,73)(H,68,76)(H,69,74)/t46-,49+,50+,51+,52-,53+,54+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474236
(CHEBI:72312 | CHEMBL3349607)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@@H](NC2=O)c1ccccc1)OC(=O)NCCN Show InChI InChI=1S/C58H66N10O9/c59-27-13-12-22-46-52(69)64-47(30-38-23-25-42(26-24-38)76-36-39-16-6-2-7-17-39)53(70)66-49(31-37-14-4-1-5-15-37)57(74)68-35-43(77-58(75)61-29-28-60)33-50(68)55(72)67-51(40-18-8-3-9-19-40)56(73)65-48(54(71)63-46)32-41-34-62-45-21-11-10-20-44(41)45/h1-11,14-21,23-26,34,43,46-51,62H,12-13,22,27-33,35-36,59-60H2,(H,61,75)(H,63,71)(H,64,69)(H,65,73)(H,66,70)(H,67,72)/t43-,46+,47+,48-,49+,50+,51+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 0.126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474221
(CHEMBL3349521)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C75H104N18O17S2/c1-41(78)64(99)81-37-60(97)83-59-40-112-111-39-58(63(79)98)91-72(107)57(38-94)90-75(110)62(44(4)96)93-71(106)55(34-47-24-12-7-13-25-47)89-74(109)61(43(3)95)92-67(102)52(29-17-19-31-77)84-70(105)56(35-48-36-80-50-27-15-14-26-49(48)50)88-69(104)54(33-46-22-10-6-11-23-46)87-68(103)53(32-45-20-8-5-9-21-45)86-65(100)42(2)82-66(101)51(85-73(59)108)28-16-18-30-76/h5-15,20-27,36,41-44,51-59,61-62,80,94-96H,16-19,28-35,37-40,76-78H2,1-4H3,(H2,79,98)(H,81,99)(H,82,101)(H,83,97)(H,84,105)(H,85,108)(H,86,100)(H,87,103)(H,88,104)(H,89,109)(H,90,110)(H,91,107)(H,92,102)(H,93,106)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474221
(CHEMBL3349521)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C75H104N18O17S2/c1-41(78)64(99)81-37-60(97)83-59-40-112-111-39-58(63(79)98)91-72(107)57(38-94)90-75(110)62(44(4)96)93-71(106)55(34-47-24-12-7-13-25-47)89-74(109)61(43(3)95)92-67(102)52(29-17-19-31-77)84-70(105)56(35-48-36-80-50-27-15-14-26-49(48)50)88-69(104)54(33-46-22-10-6-11-23-46)87-68(103)53(32-45-20-8-5-9-21-45)86-65(100)42(2)82-66(101)51(85-73(59)108)28-16-18-30-76/h5-15,20-27,36,41-44,51-59,61-62,80,94-96H,16-19,28-35,37-40,76-78H2,1-4H3,(H2,79,98)(H,81,99)(H,82,101)(H,83,97)(H,84,105)(H,85,108)(H,86,100)(H,87,103)(H,88,104)(H,89,109)(H,90,110)(H,91,107)(H,92,102)(H,93,106)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474230
(CHEMBL3349516)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C76H105N19O17S2/c1-41(79)65(101)83-38-61(99)85-59-40-114-113-39-58(64(81)100)93-66(102)42(2)84-75(111)62(43(3)96)95-73(109)55(34-47-24-12-7-13-25-47)92-76(112)63(44(4)97)94-68(104)52(29-17-19-31-78)86-71(107)56(35-48-37-82-50-27-15-14-26-49(48)50)90-70(106)54(33-46-22-10-6-11-23-46)88-69(105)53(32-45-20-8-5-9-21-45)89-72(108)57(36-60(80)98)91-67(103)51(87-74(59)110)28-16-18-30-77/h5-15,20-27,37,41-44,51-59,62-63,82,96-97H,16-19,28-36,38-40,77-79H2,1-4H3,(H2,80,98)(H2,81,100)(H,83,101)(H,84,111)(H,85,99)(H,86,107)(H,87,110)(H,88,105)(H,89,108)(H,90,106)(H,91,103)(H,92,112)(H,93,102)(H,94,104)(H,95,109)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474219
(CHEMBL3349522)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C77H107N19O18S2/c1-41(80)65(102)84-42(2)66(103)94-60-40-116-115-39-59(64(82)101)93-74(111)58(38-97)92-77(114)63(44(4)99)96-73(110)55(34-47-24-12-7-13-25-47)91-76(113)62(43(3)98)95-68(105)52(29-17-19-31-79)85-71(108)56(35-48-37-83-50-27-15-14-26-49(48)50)89-70(107)54(33-46-22-10-6-11-23-46)87-69(106)53(32-45-20-8-5-9-21-45)88-72(109)57(36-61(81)100)90-67(104)51(86-75(60)112)28-16-18-30-78/h5-15,20-27,37,41-44,51-60,62-63,83,97-99H,16-19,28-36,38-40,78-80H2,1-4H3,(H2,81,100)(H2,82,101)(H,84,102)(H,85,108)(H,86,112)(H,87,106)(H,88,109)(H,89,107)(H,90,104)(H,91,113)(H,92,114)(H,93,111)(H,94,103)(H,95,105)(H,96,110)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,62-,63-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474219
(CHEMBL3349522)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C77H107N19O18S2/c1-41(80)65(102)84-42(2)66(103)94-60-40-116-115-39-59(64(82)101)93-74(111)58(38-97)92-77(114)63(44(4)99)96-73(110)55(34-47-24-12-7-13-25-47)91-76(113)62(43(3)98)95-68(105)52(29-17-19-31-79)85-71(108)56(35-48-37-83-50-27-15-14-26-49(48)50)89-70(107)54(33-46-22-10-6-11-23-46)87-69(106)53(32-45-20-8-5-9-21-45)88-72(109)57(36-61(81)100)90-67(104)51(86-75(60)112)28-16-18-30-78/h5-15,20-27,37,41-44,51-60,62-63,83,97-99H,16-19,28-36,38-40,78-80H2,1-4H3,(H2,81,100)(H2,82,101)(H,84,102)(H,85,108)(H,86,112)(H,87,106)(H,88,109)(H,89,107)(H,90,104)(H,91,113)(H,92,114)(H,93,111)(H,94,103)(H,95,105)(H,96,110)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,62-,63-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474232
(CHEMBL3349600)Show SMILES [H][C@@]12C[C@@H](O)CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)[C@@H](C)O Show InChI InChI=1S/C44H54N8O8/c1-26(53)38-43(59)50-36(21-28-14-6-3-7-15-28)44(60)52-25-30(54)23-37(52)42(58)49-34(20-27-12-4-2-5-13-27)40(56)48-35(22-29-24-46-32-17-9-8-16-31(29)32)41(57)47-33(39(55)51-38)18-10-11-19-45/h2-9,12-17,24,26,30,33-38,46,53-54H,10-11,18-23,25,45H2,1H3,(H,47,57)(H,48,56)(H,49,58)(H,50,59)(H,51,55)/t26-,30-,33+,34+,35-,36+,37+,38+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474219
(CHEMBL3349522)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C77H107N19O18S2/c1-41(80)65(102)84-42(2)66(103)94-60-40-116-115-39-59(64(82)101)93-74(111)58(38-97)92-77(114)63(44(4)99)96-73(110)55(34-47-24-12-7-13-25-47)91-76(113)62(43(3)98)95-68(105)52(29-17-19-31-79)85-71(108)56(35-48-37-83-50-27-15-14-26-49(48)50)89-70(107)54(33-46-22-10-6-11-23-46)87-69(106)53(32-45-20-8-5-9-21-45)88-72(109)57(36-61(81)100)90-67(104)51(86-75(60)112)28-16-18-30-78/h5-15,20-27,37,41-44,51-60,62-63,83,97-99H,16-19,28-36,38-40,78-80H2,1-4H3,(H2,81,100)(H2,82,101)(H,84,102)(H,85,108)(H,86,112)(H,87,106)(H,88,109)(H,89,107)(H,90,104)(H,91,113)(H,92,114)(H,93,111)(H,94,103)(H,95,105)(H,96,110)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,62-,63-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM81767
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474221
(CHEMBL3349521)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C75H104N18O17S2/c1-41(78)64(99)81-37-60(97)83-59-40-112-111-39-58(63(79)98)91-72(107)57(38-94)90-75(110)62(44(4)96)93-71(106)55(34-47-24-12-7-13-25-47)89-74(109)61(43(3)95)92-67(102)52(29-17-19-31-77)84-70(105)56(35-48-36-80-50-27-15-14-26-49(48)50)88-69(104)54(33-46-22-10-6-11-23-46)87-68(103)53(32-45-20-8-5-9-21-45)86-65(100)42(2)82-66(101)51(85-73(59)108)28-16-18-30-76/h5-15,20-27,36,41-44,51-59,61-62,80,94-96H,16-19,28-35,37-40,76-78H2,1-4H3,(H2,79,98)(H,81,99)(H,82,101)(H,83,97)(H,84,105)(H,85,108)(H,86,100)(H,87,103)(H,88,104)(H,89,109)(H,90,110)(H,91,107)(H,92,102)(H,93,106)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM81767
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474221
(CHEMBL3349521)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C75H104N18O17S2/c1-41(78)64(99)81-37-60(97)83-59-40-112-111-39-58(63(79)98)91-72(107)57(38-94)90-75(110)62(44(4)96)93-71(106)55(34-47-24-12-7-13-25-47)89-74(109)61(43(3)95)92-67(102)52(29-17-19-31-77)84-70(105)56(35-48-36-80-50-27-15-14-26-49(48)50)88-69(104)54(33-46-22-10-6-11-23-46)87-68(103)53(32-45-20-8-5-9-21-45)86-65(100)42(2)82-66(101)51(85-73(59)108)28-16-18-30-76/h5-15,20-27,36,41-44,51-59,61-62,80,94-96H,16-19,28-35,37-40,76-78H2,1-4H3,(H2,79,98)(H,81,99)(H,82,101)(H,83,97)(H,84,105)(H,85,108)(H,86,100)(H,87,103)(H,88,104)(H,89,109)(H,90,110)(H,91,107)(H,92,102)(H,93,106)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474229
(CHEMBL3349605)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccc(O)cc1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C59H68N10O10/c60-26-10-9-17-47-53(71)65-48(30-39-20-24-43(25-21-39)78-36-40-13-5-2-6-14-40)55(73)68-51(31-37-11-3-1-4-12-37)58(76)69-35-44(79-59(77)62-28-27-61)33-52(69)57(75)67-49(29-38-18-22-42(70)23-19-38)54(72)66-50(56(74)64-47)32-41-34-63-46-16-8-7-15-45(41)46/h1-8,11-16,18-25,34,44,47-52,63,70H,9-10,17,26-33,35-36,60-61H2,(H,62,77)(H,64,74)(H,65,71)(H,66,72)(H,67,75)(H,68,73)/t44-,47+,48+,49+,50-,51+,52+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474235
(CHEMBL3349606)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN(C)C Show InChI InChI=1S/C61H72N10O9/c1-70(2)31-30-63-61(78)80-46-36-54-59(76)68-51(32-40-16-6-3-7-17-40)56(73)67-52(35-44-37-64-48-23-13-12-22-47(44)48)58(75)65-49(24-14-15-29-62)55(72)66-50(33-42-25-27-45(28-26-42)79-39-43-20-10-5-11-21-43)57(74)69-53(60(77)71(54)38-46)34-41-18-8-4-9-19-41/h3-13,16-23,25-28,37,46,49-54,64H,14-15,24,29-36,38-39,62H2,1-2H3,(H,63,78)(H,65,75)(H,66,72)(H,67,73)(H,68,76)(H,69,74)/t46-,49+,50+,51+,52-,53+,54+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474231
(CHEMBL3349513)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C73H97N17O19S2/c1-38(75)61(96)78-34-58(95)80-55-36-110-111-37-56(73(108)109)88-69(104)54(35-91)87-72(107)60(41(4)93)90-68(103)51(30-44-22-12-7-13-23-44)86-71(106)59(40(3)92)89-63(98)48(26-16-17-27-74)81-66(101)52(31-45-33-77-47-25-15-14-24-46(45)47)85-65(100)50(29-43-20-10-6-11-21-43)83-64(99)49(28-42-18-8-5-9-19-42)84-67(102)53(32-57(76)94)82-62(97)39(2)79-70(55)105/h5-15,18-25,33,38-41,48-56,59-60,77,91-93H,16-17,26-32,34-37,74-75H2,1-4H3,(H2,76,94)(H,78,96)(H,79,105)(H,80,95)(H,81,101)(H,82,97)(H,83,99)(H,84,102)(H,85,100)(H,86,106)(H,87,107)(H,88,104)(H,89,98)(H,90,103)(H,108,109)/t38-,39-,40+,41+,48-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 | PDB
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PubMed
| <0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474218
(CHEMBL3349599)Show SMILES [H][C@@]12C[C@@H](O)CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O Show InChI InChI=1S/C56H62N8O8/c57-27-13-12-22-45-51(66)60-46(29-38-23-25-42(26-24-38)72-35-39-18-8-3-9-19-39)53(68)63-49(30-37-16-6-2-7-17-37)56(71)64-34-41(65)32-50(64)55(70)62-47(28-36-14-4-1-5-15-36)52(67)61-48(54(69)59-45)31-40-33-58-44-21-11-10-20-43(40)44/h1-11,14-21,23-26,33,41,45-50,58,65H,12-13,22,27-32,34-35,57H2,(H,59,69)(H,60,66)(H,61,67)(H,62,70)(H,63,68)/t41-,45+,46+,47+,48-,49+,50+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50192018
(CHEMBL3350037)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](CO)[C@@H](C)O)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O |r| Show InChI InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29-,34-,36+,37+,38-,39+,40+,41+,42+/m1/s1 | PDB
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CHEMBL
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| Article
PubMed
| 0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474222
(CHEMBL3349604)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](CCCN=C(N)N)NC2=O)OC(=O)NCCN |wU:8.9,19.21,38.42,61.67,wD:47.51,3.78,1.0,(7.1,-8.97,;8.78,-8.16,;8.29,-9.63,;9.55,-10.54,;10.8,-9.63,;10.32,-8.16,;11.76,-7.63,;12.53,-8.96,;12.94,-6.65,;14.12,-7.63,;13.86,-9.15,;15.04,-10.14,;14.77,-11.66,;13.32,-12.2,;12.13,-11.2,;12.41,-9.68,;13.72,-5.3,;13.98,-3.79,;15.53,-3.79,;13.72,-2.27,;15.17,-1.73,;16.65,-2.13,;17.72,-1.06,;19.19,-1.45,;19.6,-2.92,;21.07,-3.32,;22.16,-2.24,;23.65,-2.64,;24.73,-1.55,;26.21,-1.94,;26.62,-3.43,;25.52,-4.51,;24.04,-4.11,;18.52,-4.01,;17.03,-3.61,;12.94,-.93,;11.76,.06,;12.53,1.4,;10.32,.6,;10.59,2.11,;12.03,2.64,;12.3,4.15,;13.74,4.68,;14.02,6.22,;8.78,.6,;7.32,.06,;6.54,1.4,;6.14,-.93,;4.95,.06,;4.18,1.4,;2.64,1.2,;1.99,2.6,;3.11,3.65,;3.09,5.2,;4.42,5.99,;5.76,5.25,;5.78,3.71,;4.46,2.91,;5.36,-2.27,;5.09,-3.79,;3.55,-3.79,;5.36,-5.3,;3.92,-5.84,;2.43,-5.43,;1.33,-6.51,;-.16,-6.11,;-1.25,-7.19,;-.85,-8.68,;-2.74,-6.79,;6.14,-6.65,;7.32,-7.63,;6.54,-8.96,;9.55,-12.06,;8.21,-12.83,;6.88,-12.06,;8.21,-14.37,;9.55,-15.14,;9.55,-16.68,;10.87,-17.47,)| Show InChI InChI=1S/C56H71N13O9/c57-24-10-9-18-43-49(70)66-45(28-36-20-22-39(23-21-36)77-34-37-14-5-2-6-15-37)51(72)68-47(29-35-12-3-1-4-13-35)54(75)69-33-40(78-56(76)62-27-25-58)31-48(69)53(74)65-44(19-11-26-61-55(59)60)50(71)67-46(52(73)64-43)30-38-32-63-42-17-8-7-16-41(38)42/h1-8,12-17,20-23,32,40,43-48,63H,9-11,18-19,24-31,33-34,57-58H2,(H,62,76)(H,64,73)(H,65,74)(H,66,70)(H,67,71)(H,68,72)(H4,59,60,61)/t40-,43+,44+,45+,46-,47+,48+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM81767
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474228
(CHEMBL3349602)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C59H68N10O9/c60-27-13-12-22-47-53(70)65-48(31-40-23-25-43(26-24-40)77-37-41-18-8-3-9-19-41)55(72)68-51(32-39-16-6-2-7-17-39)58(75)69-36-44(78-59(76)62-29-28-61)34-52(69)57(74)67-49(30-38-14-4-1-5-15-38)54(71)66-50(56(73)64-47)33-42-35-63-46-21-11-10-20-45(42)46/h1-11,14-21,23-26,35,44,47-52,63H,12-13,22,27-34,36-37,60-61H2,(H,62,76)(H,64,73)(H,65,70)(H,66,71)(H,67,74)(H,68,72)/t44-,47+,48+,49+,50-,51+,52+/m1/s1 | Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474220
(CHEMBL3349517)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C75H103N19O17S2/c1-41(78)64(100)82-37-61(98)84-59-40-113-112-39-58(63(80)99)93-73(109)57(38-95)92-65(101)42(2)83-68(104)52(31-44-19-7-4-8-20-44)91-75(111)62(43(3)96)94-67(103)51(28-16-18-30-77)85-71(107)55(34-47-36-81-49-26-14-13-25-48(47)49)89-70(106)54(33-46-23-11-6-12-24-46)87-69(105)53(32-45-21-9-5-10-22-45)88-72(108)56(35-60(79)97)90-66(102)50(86-74(59)110)27-15-17-29-76/h4-14,19-26,36,41-43,50-59,62,81,95-96H,15-18,27-35,37-40,76-78H2,1-3H3,(H2,79,97)(H2,80,99)(H,82,100)(H,83,104)(H,84,98)(H,85,107)(H,86,110)(H,87,105)(H,88,108)(H,89,106)(H,90,102)(H,91,111)(H,92,101)(H,93,109)(H,94,103)/t41-,42-,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474235
(CHEMBL3349606)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN(C)C Show InChI InChI=1S/C61H72N10O9/c1-70(2)31-30-63-61(78)80-46-36-54-59(76)68-51(32-40-16-6-3-7-17-40)56(73)67-52(35-44-37-64-48-23-13-12-22-47(44)48)58(75)65-49(24-14-15-29-62)55(72)66-50(33-42-25-27-45(28-26-42)79-39-43-20-10-5-11-21-43)57(74)69-53(60(77)71(54)38-46)34-41-18-8-4-9-19-41/h3-13,16-23,25-28,37,46,49-54,64H,14-15,24,29-36,38-39,62H2,1-2H3,(H,63,78)(H,65,75)(H,66,72)(H,67,73)(H,68,76)(H,69,74)/t46-,49+,50+,51+,52-,53+,54+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474231
(CHEMBL3349513)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C73H97N17O19S2/c1-38(75)61(96)78-34-58(95)80-55-36-110-111-37-56(73(108)109)88-69(104)54(35-91)87-72(107)60(41(4)93)90-68(103)51(30-44-22-12-7-13-23-44)86-71(106)59(40(3)92)89-63(98)48(26-16-17-27-74)81-66(101)52(31-45-33-77-47-25-15-14-24-46(45)47)85-65(100)50(29-43-20-10-6-11-21-43)83-64(99)49(28-42-18-8-5-9-19-42)84-67(102)53(32-57(76)94)82-62(97)39(2)79-70(55)105/h5-15,18-25,33,38-41,48-56,59-60,77,91-93H,16-17,26-32,34-37,74-75H2,1-4H3,(H2,76,94)(H,78,96)(H,79,105)(H,80,95)(H,81,101)(H,82,97)(H,83,99)(H,84,102)(H,85,100)(H,86,106)(H,87,107)(H,88,104)(H,89,98)(H,90,103)(H,108,109)/t38-,39-,40+,41+,48-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474220
(CHEMBL3349517)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C75H103N19O17S2/c1-41(78)64(100)82-37-61(98)84-59-40-113-112-39-58(63(80)99)93-73(109)57(38-95)92-65(101)42(2)83-68(104)52(31-44-19-7-4-8-20-44)91-75(111)62(43(3)96)94-67(103)51(28-16-18-30-77)85-71(107)55(34-47-36-81-49-26-14-13-25-48(47)49)89-70(106)54(33-46-23-11-6-12-24-46)87-69(105)53(32-45-21-9-5-10-22-45)88-72(108)56(35-60(79)97)90-66(102)50(86-74(59)110)27-15-17-29-76/h4-14,19-26,36,41-43,50-59,62,81,95-96H,15-18,27-35,37-40,76-78H2,1-3H3,(H2,79,97)(H2,80,99)(H,82,100)(H,83,104)(H,84,98)(H,85,107)(H,86,110)(H,87,105)(H,88,108)(H,89,106)(H,90,102)(H,91,111)(H,92,101)(H,93,109)(H,94,103)/t41-,42-,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM82470
(3-(2-Naphtyl)-D-Ala-L-Cys(1)-L-Tyr-D-Trp-L-Lys-L-V...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C54H69N11O10S2/c1-29(2)45-54(75)63-44(53(74)65-46(30(3)66)47(57)68)28-77-76-27-43(62-48(69)38(56)23-32-15-18-33-10-4-5-11-34(33)22-32)52(73)60-41(24-31-16-19-36(67)20-17-31)50(71)61-42(25-35-26-58-39-13-7-6-12-37(35)39)51(72)59-40(49(70)64-45)14-8-9-21-55/h4-7,10-13,15-20,22,26,29-30,38,40-46,58,66-67H,8-9,14,21,23-25,27-28,55-56H2,1-3H3,(H2,57,68)(H,59,72)(H,60,73)(H,61,71)(H,62,69)(H,63,75)(H,64,70)(H,65,74)/t30-,38-,40+,41+,42-,43+,44+,45+,46+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474225
(CHEMBL3349524)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C75H103N19O17S2/c1-41(78)64(100)82-37-61(98)84-59-40-113-112-39-58(63(80)99)93-73(109)57(38-95)92-75(111)62(43(3)96)94-72(108)54(33-46-23-11-6-12-24-46)87-65(101)42(2)83-66(102)50(27-15-17-29-76)85-70(106)55(34-47-36-81-49-26-14-13-25-48(47)49)90-69(105)53(32-45-21-9-5-10-22-45)88-68(104)52(31-44-19-7-4-8-20-44)89-71(107)56(35-60(79)97)91-67(103)51(86-74(59)110)28-16-18-30-77/h4-14,19-26,36,41-43,50-59,62,81,95-96H,15-18,27-35,37-40,76-78H2,1-3H3,(H2,79,97)(H2,80,99)(H,82,100)(H,83,102)(H,84,98)(H,85,106)(H,86,110)(H,87,101)(H,88,104)(H,89,107)(H,90,105)(H,91,103)(H,92,111)(H,93,109)(H,94,108)/t41-,42-,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474233
(CHEMBL3349603)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCCCCN Show InChI InChI=1S/C62H74N10O9/c63-30-14-4-16-32-65-62(79)81-47-37-55-60(77)70-52(33-41-17-5-1-6-18-41)57(74)69-53(36-45-38-66-49-24-12-11-23-48(45)49)59(76)67-50(25-13-15-31-64)56(73)68-51(34-43-26-28-46(29-27-43)80-40-44-21-9-3-10-22-44)58(75)71-54(61(78)72(55)39-47)35-42-19-7-2-8-20-42/h1-3,5-12,17-24,26-29,38,47,50-55,66H,4,13-16,25,30-37,39-40,63-64H2,(H,65,79)(H,67,76)(H,68,73)(H,69,74)(H,70,77)(H,71,75)/t47-,50+,51+,52+,53-,54+,55+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50065453
((5S,8S,11S,14R,17S,19aS)-11-(4-Amino-butyl)-5,17-d...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O Show InChI InChI=1S/C44H54N8O7/c1-27(53)38-43(58)50-36(24-29-15-6-3-7-16-29)44(59)52-22-12-20-37(52)42(57)49-34(23-28-13-4-2-5-14-28)40(55)48-35(25-30-26-46-32-18-9-8-17-31(30)32)41(56)47-33(39(54)51-38)19-10-11-21-45/h2-9,13-18,26-27,33-38,46,53H,10-12,19-25,45H2,1H3,(H,47,56)(H,48,55)(H,49,57)(H,50,58)(H,51,54)/t27-,33+,34+,35-,36+,37+,38+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474220
(CHEMBL3349517)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C75H103N19O17S2/c1-41(78)64(100)82-37-61(98)84-59-40-113-112-39-58(63(80)99)93-73(109)57(38-95)92-65(101)42(2)83-68(104)52(31-44-19-7-4-8-20-44)91-75(111)62(43(3)96)94-67(103)51(28-16-18-30-77)85-71(107)55(34-47-36-81-49-26-14-13-25-48(47)49)89-70(106)54(33-46-23-11-6-12-24-46)87-69(105)53(32-45-21-9-5-10-22-45)88-72(108)56(35-60(79)97)90-66(102)50(86-74(59)110)27-15-17-29-76/h4-14,19-26,36,41-43,50-59,62,81,95-96H,15-18,27-35,37-40,76-78H2,1-3H3,(H2,79,97)(H2,80,99)(H,82,100)(H,83,104)(H,84,98)(H,85,107)(H,86,110)(H,87,105)(H,88,108)(H,89,106)(H,90,102)(H,91,111)(H,92,101)(H,93,109)(H,94,103)/t41-,42-,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474230
(CHEMBL3349516)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C76H105N19O17S2/c1-41(79)65(101)83-38-61(99)85-59-40-114-113-39-58(64(81)100)93-66(102)42(2)84-75(111)62(43(3)96)95-73(109)55(34-47-24-12-7-13-25-47)92-76(112)63(44(4)97)94-68(104)52(29-17-19-31-78)86-71(107)56(35-48-37-82-50-27-15-14-26-49(48)50)90-70(106)54(33-46-22-10-6-11-23-46)88-69(105)53(32-45-20-8-5-9-21-45)89-72(108)57(36-60(80)98)91-67(103)51(87-74(59)110)28-16-18-30-77/h5-15,20-27,37,41-44,51-59,62-63,82,96-97H,16-19,28-36,38-40,77-79H2,1-4H3,(H2,80,98)(H2,81,100)(H,83,101)(H,84,111)(H,85,99)(H,86,107)(H,87,110)(H,88,105)(H,89,108)(H,90,106)(H,91,103)(H,92,112)(H,93,102)(H,94,104)(H,95,109)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474229
(CHEMBL3349605)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccc(O)cc1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C59H68N10O10/c60-26-10-9-17-47-53(71)65-48(30-39-20-24-43(25-21-39)78-36-40-13-5-2-6-14-40)55(73)68-51(31-37-11-3-1-4-12-37)58(76)69-35-44(79-59(77)62-28-27-61)33-52(69)57(75)67-49(29-38-18-22-42(70)23-19-38)54(72)66-50(56(74)64-47)32-41-34-63-46-16-8-7-15-45(41)46/h1-8,11-16,18-25,34,44,47-52,63,70H,9-10,17,26-33,35-36,60-61H2,(H,62,77)(H,64,74)(H,65,71)(H,66,72)(H,67,75)(H,68,73)/t44-,47+,48+,49+,50-,51+,52+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM81767
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r| Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474216
(CHEMBL3349518)Show SMILES [H][C@]1(NC(=O)[C@H](C)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C70H101N19O18S2/c1-36(73)59(96)77-32-55(94)79-53-35-109-108-34-52(58(75)95)87-67(104)51(33-90)86-70(107)57(39(4)92)88-60(97)37(2)78-69(106)56(38(3)91)89-62(99)46(24-14-16-26-72)80-65(102)49(29-42-31-76-44-22-12-11-21-43(42)44)84-64(101)48(28-41-19-9-6-10-20-41)82-63(100)47(27-40-17-7-5-8-18-40)83-66(103)50(30-54(74)93)85-61(98)45(81-68(53)105)23-13-15-25-71/h5-12,17-22,31,36-39,45-53,56-57,76,90-92H,13-16,23-30,32-35,71-73H2,1-4H3,(H2,74,93)(H2,75,95)(H,77,96)(H,78,106)(H,79,94)(H,80,102)(H,81,105)(H,82,100)(H,83,103)(H,84,101)(H,85,98)(H,86,107)(H,87,104)(H,88,97)(H,89,99)/t36-,37-,38+,39+,45-,46-,47-,48-,49-,50-,51-,52-,53-,56-,57-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474221
(CHEMBL3349521)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C75H104N18O17S2/c1-41(78)64(99)81-37-60(97)83-59-40-112-111-39-58(63(79)98)91-72(107)57(38-94)90-75(110)62(44(4)96)93-71(106)55(34-47-24-12-7-13-25-47)89-74(109)61(43(3)95)92-67(102)52(29-17-19-31-77)84-70(105)56(35-48-36-80-50-27-15-14-26-49(48)50)88-69(104)54(33-46-22-10-6-11-23-46)87-68(103)53(32-45-20-8-5-9-21-45)86-65(100)42(2)82-66(101)51(85-73(59)108)28-16-18-30-76/h5-15,20-27,36,41-44,51-59,61-62,80,94-96H,16-19,28-35,37-40,76-78H2,1-4H3,(H2,79,98)(H,81,99)(H,82,101)(H,83,97)(H,84,105)(H,85,108)(H,86,100)(H,87,103)(H,88,104)(H,89,109)(H,90,110)(H,91,107)(H,92,102)(H,93,106)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,61-,62-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474220
(CHEMBL3349517)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C75H103N19O17S2/c1-41(78)64(100)82-37-61(98)84-59-40-113-112-39-58(63(80)99)93-73(109)57(38-95)92-65(101)42(2)83-68(104)52(31-44-19-7-4-8-20-44)91-75(111)62(43(3)96)94-67(103)51(28-16-18-30-77)85-71(107)55(34-47-36-81-49-26-14-13-25-48(47)49)89-70(106)54(33-46-23-11-6-12-24-46)87-69(105)53(32-45-21-9-5-10-22-45)88-72(108)56(35-60(79)97)90-66(102)50(86-74(59)110)27-15-17-29-76/h4-14,19-26,36,41-43,50-59,62,81,95-96H,15-18,27-35,37-40,76-78H2,1-3H3,(H2,79,97)(H2,80,99)(H,82,100)(H,83,104)(H,84,98)(H,85,107)(H,86,110)(H,87,105)(H,88,108)(H,89,106)(H,90,102)(H,91,111)(H,92,101)(H,93,109)(H,94,103)/t41-,42-,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474229
(CHEMBL3349605)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccc(O)cc1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C59H68N10O10/c60-26-10-9-17-47-53(71)65-48(30-39-20-24-43(25-21-39)78-36-40-13-5-2-6-14-40)55(73)68-51(31-37-11-3-1-4-12-37)58(76)69-35-44(79-59(77)62-28-27-61)33-52(69)57(75)67-49(29-38-18-22-42(70)23-19-38)54(72)66-50(56(74)64-47)32-41-34-63-46-16-8-7-15-45(41)46/h1-8,11-16,18-25,34,44,47-52,63,70H,9-10,17,26-33,35-36,60-61H2,(H,62,77)(H,64,74)(H,65,71)(H,66,72)(H,67,75)(H,68,73)/t44-,47+,48+,49+,50-,51+,52+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474219
(CHEMBL3349522)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C77H107N19O18S2/c1-41(80)65(102)84-42(2)66(103)94-60-40-116-115-39-59(64(82)101)93-74(111)58(38-97)92-77(114)63(44(4)99)96-73(110)55(34-47-24-12-7-13-25-47)91-76(113)62(43(3)98)95-68(105)52(29-17-19-31-79)85-71(108)56(35-48-37-83-50-27-15-14-26-49(48)50)89-70(107)54(33-46-22-10-6-11-23-46)87-69(106)53(32-45-20-8-5-9-21-45)88-72(109)57(36-61(81)100)90-67(104)51(86-75(60)112)28-16-18-30-78/h5-15,20-27,37,41-44,51-60,62-63,83,97-99H,16-19,28-36,38-40,78-80H2,1-4H3,(H2,81,100)(H2,82,101)(H,84,102)(H,85,108)(H,86,112)(H,87,106)(H,88,109)(H,89,107)(H,90,104)(H,91,113)(H,92,114)(H,93,111)(H,94,103)(H,95,105)(H,96,110)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,62-,63-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474218
(CHEMBL3349599)Show SMILES [H][C@@]12C[C@@H](O)CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O Show InChI InChI=1S/C56H62N8O8/c57-27-13-12-22-45-51(66)60-46(29-38-23-25-42(26-24-38)72-35-39-18-8-3-9-19-39)53(68)63-49(30-37-16-6-2-7-17-37)56(71)64-34-41(65)32-50(64)55(70)62-47(28-36-14-4-1-5-15-36)52(67)61-48(54(69)59-45)31-40-33-58-44-21-11-10-20-43(40)44/h1-11,14-21,23-26,33,41,45-50,58,65H,12-13,22,27-32,34-35,57H2,(H,59,69)(H,60,66)(H,61,67)(H,62,70)(H,63,68)/t41-,45+,46+,47+,48-,49+,50+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474236
(CHEBI:72312 | CHEMBL3349607)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@@H](NC2=O)c1ccccc1)OC(=O)NCCN Show InChI InChI=1S/C58H66N10O9/c59-27-13-12-22-46-52(69)64-47(30-38-23-25-42(26-24-38)76-36-39-16-6-2-7-17-39)53(70)66-49(31-37-14-4-1-5-15-37)57(74)68-35-43(77-58(75)61-29-28-60)33-50(68)55(72)67-51(40-18-8-3-9-19-40)56(73)65-48(54(71)63-46)32-41-34-62-45-21-11-10-20-44(41)45/h1-11,14-21,23-26,34,43,46-51,62H,12-13,22,27-33,35-36,59-60H2,(H,61,75)(H,63,71)(H,64,69)(H,65,73)(H,66,70)(H,67,72)/t43-,46+,47+,48-,49+,50+,51+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(Homo sapiens (Human)) | BDBM50474226
(CHEMBL3349601)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1c[nH]cn1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C56H66N12O9/c57-22-10-9-17-44-50(69)64-45(25-36-18-20-40(21-19-36)76-33-37-13-5-2-6-14-37)51(70)67-48(26-35-11-3-1-4-12-35)55(74)68-32-41(77-56(75)60-24-23-58)29-49(68)54(73)66-47(28-39-31-59-34-62-39)53(72)65-46(52(71)63-44)27-38-30-61-43-16-8-7-15-42(38)43/h1-8,11-16,18-21,30-31,34,41,44-49,61H,9-10,17,22-29,32-33,57-58H2,(H,59,62)(H,60,75)(H,63,71)(H,64,69)(H,65,72)(H,66,73)(H,67,70)/t41-,44+,45+,46-,47+,48+,49+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474228
(CHEMBL3349602)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C59H68N10O9/c60-27-13-12-22-47-53(70)65-48(31-40-23-25-43(26-24-40)77-37-41-18-8-3-9-19-41)55(72)68-51(32-39-16-6-2-7-17-39)58(75)69-36-44(78-59(76)62-29-28-61)34-52(69)57(74)67-49(30-38-14-4-1-5-15-38)54(71)66-50(56(73)64-47)33-42-35-63-46-21-11-10-20-45(42)46/h1-11,14-21,23-26,35,44,47-52,63H,12-13,22,27-34,36-37,60-61H2,(H,62,76)(H,64,73)(H,65,70)(H,66,71)(H,67,74)(H,68,72)/t44-,47+,48+,49+,50-,51+,52+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 3
(Homo sapiens (Human)) | BDBM50474226
(CHEMBL3349601)Show SMILES [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1c[nH]cn1)NC2=O)OC(=O)NCCN Show InChI InChI=1S/C56H66N12O9/c57-22-10-9-17-44-50(69)64-45(25-36-18-20-40(21-19-36)76-33-37-13-5-2-6-14-37)51(70)67-48(26-35-11-3-1-4-12-35)55(74)68-32-41(77-56(75)60-24-23-58)29-49(68)54(73)66-47(28-39-31-59-34-62-39)53(72)65-46(52(71)63-44)27-38-30-61-43-16-8-7-15-42(38)43/h1-8,11-16,18-21,30-31,34,41,44-49,61H,9-10,17,22-29,32-33,57-58H2,(H,59,62)(H,60,75)(H,63,71)(H,64,69)(H,65,72)(H,66,73)(H,67,70)/t41-,44+,45+,46-,47+,48+,49+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 5
(Homo sapiens (Human)) | BDBM50474230
(CHEMBL3349516)Show SMILES [H][C@]1(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C76H105N19O17S2/c1-41(79)65(101)83-38-61(99)85-59-40-114-113-39-58(64(81)100)93-66(102)42(2)84-75(111)62(43(3)96)95-73(109)55(34-47-24-12-7-13-25-47)92-76(112)63(44(4)97)94-68(104)52(29-17-19-31-78)86-71(107)56(35-48-37-82-50-27-15-14-26-49(48)50)90-70(106)54(33-46-22-10-6-11-23-46)88-69(105)53(32-45-20-8-5-9-21-45)89-72(108)57(36-60(80)98)91-67(103)51(87-74(59)110)28-16-18-30-77/h5-15,20-27,37,41-44,51-59,62-63,82,96-97H,16-19,28-36,38-40,77-79H2,1-4H3,(H2,80,98)(H2,81,100)(H,83,101)(H,84,111)(H,85,99)(H,86,107)(H,87,110)(H,88,105)(H,89,108)(H,90,106)(H,91,103)(H,92,112)(H,93,102)(H,94,104)(H,95,109)/t41-,42-,43+,44+,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1
(Homo sapiens (Human)) | BDBM50474231
(CHEMBL3349513)Show SMILES [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O Show InChI InChI=1S/C73H97N17O19S2/c1-38(75)61(96)78-34-58(95)80-55-36-110-111-37-56(73(108)109)88-69(104)54(35-91)87-72(107)60(41(4)93)90-68(103)51(30-44-22-12-7-13-23-44)86-71(106)59(40(3)92)89-63(98)48(26-16-17-27-74)81-66(101)52(31-45-33-77-47-25-15-14-24-46(45)47)85-65(100)50(29-43-20-10-6-11-21-43)83-64(99)49(28-42-18-8-5-9-19-42)84-67(102)53(32-57(76)94)82-62(97)39(2)79-70(55)105/h5-15,18-25,33,38-41,48-56,59-60,77,91-93H,16-17,26-32,34-37,74-75H2,1-4H3,(H2,76,94)(H,78,96)(H,79,105)(H,80,95)(H,81,101)(H,82,97)(H,83,99)(H,84,102)(H,85,100)(H,86,106)(H,87,107)(H,88,104)(H,89,98)(H,90,103)(H,108,109)/t38-,39-,40+,41+,48-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 4
(Homo sapiens (Human)) | BDBM50474216
(CHEMBL3349518)Show SMILES [H][C@]1(NC(=O)[C@H](C)NC(=O)[C@@]([H])(NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(N)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O Show InChI InChI=1S/C70H101N19O18S2/c1-36(73)59(96)77-32-55(94)79-53-35-109-108-34-52(58(75)95)87-67(104)51(33-90)86-70(107)57(39(4)92)88-60(97)37(2)78-69(106)56(38(3)91)89-62(99)46(24-14-16-26-72)80-65(102)49(29-42-31-76-44-22-12-11-21-43(42)44)84-64(101)48(28-41-19-9-6-10-20-41)82-63(100)47(27-40-17-7-5-8-18-40)83-66(103)50(30-54(74)93)85-61(98)45(81-68(53)105)23-13-15-25-71/h5-12,17-22,31,36-39,45-53,56-57,76,90-92H,13-16,23-30,32-35,71-73H2,1-4H3,(H2,74,93)(H2,75,95)(H,77,96)(H,78,106)(H,79,94)(H,80,102)(H,81,105)(H,82,100)(H,83,103)(H,84,101)(H,85,98)(H,86,107)(H,87,104)(H,88,97)(H,89,99)/t36-,37-,38+,39+,45-,46-,47-,48-,49-,50-,51-,52-,53-,56-,57-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma
Curated by ChEMBL
| Assay Description
Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells |
J Med Chem 46: 2334-44 (2003)
Article DOI: 10.1021/jm021093t
BindingDB Entry DOI: 10.7270/Q2CR5X31 |
More data for this
Ligand-Target Pair | |
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