BindingDB PrimarySearch

Found 52 hits with Last Name = 'leyers' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation counting				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294038 (CHEMBL116734 \| LY-329146 \| N-(4-(6-hydroxy-3-(4-(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation counting				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294036 (2-(3,3-Diethylthioureido)benzo[b]thiophene-3-carbo...) Show SMILES CCN(CC)C(=S)Nc1sc2ccccc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	932	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50084979 (3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50244521 ((4-[(5,6,7,8-tetrahydro-4-oxo-4H-[1]benzothieno[2,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294037 (2-(3-Cyclohexyl-3-methylthioureido)benzo[b]thiophe...) Show SMILES CN(C1CCCCC1)C(=S)Nc1sc2ccccc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50111915 (2-(3-(9-chloro-3-methyl-4-oxoisoxazolo[4,3-c]quino...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation counting				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294032 (2-(3,3-Diethylthioureido)-5,6-dihydro-4H-cyclopent...) Show SMILES CCN(CC)C(=S)Nc1sc2CCCc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294033 (2-(3,3-Diethylthioureido)-4,5,6,7-tetrahydrobenzo[...) Show SMILES CCN(CC)C(=S)Nc1sc2CCCCc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of recombinant MRP1 expressed in human HeLa T5 cells assessed as ATP-dependent transport of [3H]para-aminohippurate				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294034 ((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...) Show SMILES CCN(CC)C(=S)Nc1sc2CCCC(C)c2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294041 (3-(3,3-Diethylthioureido)thiophene-2-carboxylic Ac...) Show SMILES CCN(CC)C(=O)Nc1ccsc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294048 (2-(3-Cyclohexyl-3-methylthioureido)-4,5-dimethylth...) Show SMILES CN(C1CCCCC1)C(=S)Nc1sc(C)c(C)c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294042 (2-(3,3-Diethylthioureido)thiophene-3-carboxylic Ac...) Show SMILES CCN(CC)C(=S)Nc1sccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294043 (2-(3-Cyclohexyl-3-methylthioureido)thiophene-3-car...) Show SMILES CN(C1CCCCC1)C(=S)Nc1sccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50022815 ((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294055 (3-(3,3-Diethylureido)-2-naphthoic Acid \| CHEMBL552...) Show SMILES CCN(CC)C(=O)Nc1cc2ccccc2cc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294035 (2-(3,3-Diethylthioureido)-5,6,7,8-tetrahydro-4H-cy...) Show SMILES CCN(CC)C(=S)Nc1sc2CCCCCc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50294036 (2-(3,3-Diethylthioureido)benzo[b]thiophene-3-carbo...) Show SMILES CCN(CC)C(=S)Nc1sc2ccccc2c1C(O)=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 staining				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50052019 (CHEMBL89768 \| L-660771 \| MK-571 \| Sodium; 3-[{3-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294040 (2-(3,3-Diethylureido)-4,5,6,7-tetrahydrobenzo[b]th...) Show SMILES CCN(CC)C(=O)Nc1sc2CCCCc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50294034 ((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...) Show SMILES CCN(CC)C(=S)Nc1sc2CCCC(C)c2c1C(O)=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 staining				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50338982 ((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50294043 (2-(3-Cyclohexyl-3-methylthioureido)thiophene-3-car...) Show SMILES CN(C1CCCCC1)C(=S)Nc1sccc1C(O)=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 staining				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294039 (2-(3,3-Diethylureido)-5,6-dihydro-4H-cyclopenta[b]...) Show SMILES CCN(CC)C(=O)Nc1sc2CCCc2c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294050 (2-(3-Cyclohexyl-3-methylureido)benzoic Acid \| CHEM...) Show SMILES CN(C1CCCCC1)C(=O)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50022815 ((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP2 expressed in dog MDCK2 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294045 (2-(3,3-Diethylthioureido)-5-phenylthiophene-3-carb...) Show SMILES CCN(CC)C(=S)Nc1sc(cc1C(O)=O)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294044 (2-(3,3-Diethylthioureido)-4-isopropylthiophene-3-c...) Show SMILES CCN(CC)C(=S)Nc1scc(C(C)C)c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294057 (2-(3-Cyclohexyl-3-methylthioureido)benzoic Acid \| ...) Show SMILES CN(C1CCCCC1)C(=S)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294030 (4,5-Dimethyl-2-[(4-morpholinylthiocarbonyl)amino]t...) Show SMILES Cc1sc(NC(=S)N2CCOCC2)c(C(O)=O)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294061 (2-[(1-Pyrrolidinylthiocarbonyl)amino]benzoic Acid ...) Show SMILES OC(=O)c1ccccc1NC(=S)N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50244522 (4-(3-(3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP1 in human 2008 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294047 (2-(3,3-Diethylthioureido)-4,5-dimethylthiophene-3-...) Show SMILES CCN(CC)C(=S)Nc1sc(C)c(C)c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294062 (2-[(1-Piperidinylthiocarbonyl)amino]benzoic Acid \|...) Show SMILES OC(=O)c1ccccc1NC(=S)N1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50052019 (CHEMBL89768 \| L-660771 \| MK-571 \| Sodium; 3-[{3-[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP2 expressed in dog MDCK2 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50244521 ((4-[(5,6,7,8-tetrahydro-4-oxo-4H-[1]benzothieno[2,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP2 expressed in dog MDCK2 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294056 (2-(3,3-Diethylthioureido)benzoic Acid \| CHEMBL5696...) Show SMILES CCN(CC)C(=S)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294053 (2-(3-Cyclohexyl-3-methylureido)-5-methylbenzoic Ac...) Show SMILES CN(C1CCCCC1)C(=O)Nc1ccc(C)cc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294060 (2-[3-Methyl-3-(2-phenylethyl)thioureido]benzoic Ac...) Show SMILES CN(CCc1ccccc1)C(=S)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294049 (2-(3,3-diethylureido)benzoic acid \| CHEMBL558351) Show SMILES CCN(CC)C(=O)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294046 (2-[(4-Morpholinylthiocarbonyl)amino]-5-phenylthiop...) Show SMILES OC(=O)c1cc(sc1NC(=S)N1CCOCC1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294059 (2-(3-Benzyl-3-methylthioureido)benzoic Acid \| CHEM...) Show SMILES CN(Cc1ccccc1)C(=S)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294051 (2-(3-Benzyl-3-methylureido)benzoic Acid \| CHEMBL55...) Show SMILES CN(Cc1ccccc1)C(=O)Nc1ccccc1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294052 (2-[(1-Pyrrolidinylcarbonyl)amino]benzoic Acid \| CH...) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294054 (4,5-Dimethyl-2-[(4-morpholinylcarbonyl)amino]benzo...) Show SMILES Cc1cc(NC(=O)N2CCOCC2)c(cc1C)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294031 (5-Carbamoyl-2-(3,3-diethylthioureido)-4-methylthio...) Show SMILES CCN(CC)C(=S)Nc1sc(C(N)=O)c(C)c1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 1 (Homo sapiens (Human))	BDBM50294058 (2-(3-Methyl-3-phenylthioureido)benzoic Acid \| CHEM...) Show SMILES CN(C(=S)Nc1ccccc1C(O)=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...				J Med Chem 52: 4586-95 (2009) Article DOI: 10.1021/jm900688v BindingDB Entry DOI: 10.7270/Q22V2G46
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50244522 (4-(3-(3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human MRP2 expressed in dog MDCK2 cells				Bioorg Med Chem Lett 18: 4761-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.127 BindingDB Entry DOI: 10.7270/Q2QZ2BWB
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair

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