Compile Data Set for Download or QSAR

Found 214 hits with Last Name = 'lim' and Initial = 'km'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222640 (CHEMBL415543) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H32N2O2S/c1-31-26-21-24(14-15-25(26)30)13-8-19-29(20-17-23-11-6-3-7-12-23)27(32)28-18-16-22-9-4-2-5-10-22/h2-7,9-12,14-15,21,30H,8,13,16-20H2,1H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222640 (CHEMBL415543) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H32N2O2S/c1-31-26-21-24(14-15-25(26)30)13-8-19-29(20-17-23-11-6-3-7-12-23)27(32)28-18-16-22-9-4-2-5-10-22/h2-7,9-12,14-15,21,30H,8,13,16-20H2,1H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222695 (CHEMBL155433) Show SMILES COc1cc(CCCN(C(c2ccccc2)c2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C32H34N2O2S/c1-36-30-24-26(19-20-29(30)35)14-11-23-34(32(37)33-22-21-25-12-5-2-6-13-25)31(27-15-7-3-8-16-27)28-17-9-4-10-18-28/h2-10,12-13,15-20,24,31,35H,11,14,21-23H2,1H3,(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222637 (CHEMBL154743) Show SMILES COc1cc(CCCN(CCc2ccc(cc2)[N+]([O-])=O)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31N3O4S/c1-34-26-20-23(11-14-25(26)31)8-5-18-29(19-16-22-9-12-24(13-10-22)30(32)33)27(35)28-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,28,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222696 (CHEMBL156041) Show SMILES COc1cc(CCCN(CCc2ccc(Cl)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31ClN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-22-9-12-24(28)13-10-22)27(33)29-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222635 (CHEMBL267205) Show SMILES COc1ccc(CCN(CCCc2ccc(O)c(OC)c2)C(\S)=N\CCc2ccccc2)cc1 Show InChI InChI=1S/C28H34N2O3S/c1-32-25-13-10-23(11-14-25)17-20-30(28(34)29-18-16-22-7-4-3-5-8-22)19-6-9-24-12-15-26(31)27(21-24)33-2/h3-5,7-8,10-15,21,31H,6,9,16-20H2,1-2H3,(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222649 (CHEMBL155730) Show SMILES COc1cc(CCCN(Cc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C26H30N2O2S/c1-30-25-19-22(14-15-24(25)29)13-8-18-28(20-23-11-6-3-7-12-23)26(31)27-17-16-21-9-4-2-5-10-21/h2-7,9-12,14-15,19,29H,8,13,16-18,20H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222647 (CHEMBL154990) Show SMILES COc1cc(CCCN(CCc2ccc(C)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-22-10-12-24(13-11-22)17-20-30(28(33)29-18-16-23-7-4-3-5-8-23)19-6-9-25-14-15-26(31)27(21-25)32-2/h3-5,7-8,10-15,21,31H,6,9,16-20H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222641 (CHEMBL157962) Show SMILES COc1cc(CCCN(CCc2ccc(F)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31FN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-22-9-12-24(28)13-10-22)27(33)29-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222638 (CHEMBL422702) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C27H31ClN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-21-6-3-2-4-7-21)27(33)29-17-15-22-9-12-24(28)13-10-22/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222644 (CHEMBL434295) Show SMILES COc1cc(CCCN(C(C)C)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C22H30N2O2S/c1-17(2)24(22(27)23-14-13-18-8-5-4-6-9-18)15-7-10-19-11-12-20(25)21(16-19)26-3/h4-6,8-9,11-12,16-17,25H,7,10,13-15H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222648 (CHEMBL156693) Show SMILES COc1cc(CCCN(C2CCCCC2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C25H34N2O2S/c1-29-24-19-21(14-15-23(24)28)11-8-18-27(22-12-6-3-7-13-22)25(30)26-17-16-20-9-4-2-5-10-20/h2,4-5,9-10,14-15,19,22,28H,3,6-8,11-13,16-18H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222639 (CHEMBL356682) Show SMILES COc1cc(CCCN(CCCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-32-27-22-25(16-17-26(27)31)15-9-21-30(20-8-14-23-10-4-2-5-11-23)28(33)29-19-18-24-12-6-3-7-13-24/h2-7,10-13,16-17,22,31H,8-9,14-15,18-21H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474740 (CHEMBL355074) Show SMILES CCCCc1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O |t:11| Show InChI InChI=1S/C23H26O4S/c1-5-6-7-16-8-10-17(11-9-16)20-21(27-23(2,3)22(20)24)18-12-14-19(15-13-18)28(4,25)26/h8-15H,5-7H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.02	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222646 (CHEMBL157917) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccc(F)cc2)ccc1O Show InChI InChI=1S/C27H31FN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-21-6-3-2-4-7-21)27(33)29-17-15-22-9-12-24(28)13-10-22/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222694 (CHEMBL158189) Show SMILES COc1cc(CCCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-32-27-22-25(15-16-26(27)31)14-8-9-20-30(21-18-24-12-6-3-7-13-24)28(33)29-19-17-23-10-4-2-5-11-23/h2-7,10-13,15-16,22,31H,8-9,14,17-21H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474747 (CHEMBL167357) Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1F)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H14F3NO4S/c1-18(2)17(23)15(9-5-10(19)7-11(20)6-9)16(26-18)13-4-3-12(8-14(13)21)27(22,24)25/h3-8H,1-2H3,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.55	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474743 (CHEMBL353935) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1F)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H15F2NO4S/c1-18(2)17(22)15(10-4-3-5-11(19)8-10)16(25-18)13-7-6-12(9-14(13)20)26(21,23)24/h3-9H,1-2H3,(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.91	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474760 (CG-100649 | CG100649 | Polmacoxib) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222691 (CHEMBL156927) Show SMILES CC(C)N(CCCc1ccc(O)c(O)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2O2S/c1-16(2)23(14-6-9-18-10-11-19(24)20(25)15-18)21(26)22-13-12-17-7-4-3-5-8-17/h3-5,7-8,10-11,15-16,24-25H,6,9,12-14H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222690 (CHEMBL345157) Show SMILES CCCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C23H32N2O2S/c1-3-4-16-25(23(28)24-15-14-19-9-6-5-7-10-19)17-8-11-20-12-13-21(26)22(18-20)27-2/h5-7,9-10,12-13,18,26H,3-4,8,11,14-17H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222645 (CHEMBL157918) Show SMILES COc1ccc(CCCN(C(C)C)C(\S)=N\CCc2ccccc2)cc1OC Show InChI InChI=1S/C23H32N2O2S/c1-18(2)25(23(28)24-15-14-19-9-6-5-7-10-19)16-8-11-20-12-13-21(26-3)22(17-20)27-4/h5-7,9-10,12-13,17-18H,8,11,14-16H2,1-4H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222693 (CHEMBL157579) Show SMILES CCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C22H30N2O2S/c1-3-15-24(22(27)23-14-13-18-8-5-4-6-9-18)16-7-10-19-11-12-20(25)21(17-19)26-2/h4-6,8-9,11-12,17,25H,3,7,10,13-16H2,1-2H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474737 (CHEMBL167011) Show SMILES CC1(C)OC(=C(C1=O)c1ccc(F)c(F)c1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H15F2NO4S/c1-18(2)17(22)15(11-5-8-13(19)14(20)9-11)16(25-18)10-3-6-12(7-4-10)26(21,23)24/h3-9H,1-2H3,(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474742 (CHEMBL166295) Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H17NO4S/c1-18(2)17(20)15(12-6-4-3-5-7-12)16(23-18)13-8-10-14(11-9-13)24(19,21)22/h3-11H,1-2H3,(H2,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23.3	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	26.2	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical& Health Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Prostaglandin G/H synthase 2 from freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 14: 2195-8 (2004) BindingDB Entry DOI: 10.7270/Q2K939PT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218963 (CHEMBL297626) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages				Bioorg Med Chem Lett 14: 1757-60 (2004) BindingDB Entry DOI: 10.7270/Q2ZK5JVW
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218963 (CHEMBL297626) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218963 (CHEMBL297626) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
Pacific Corporation R&D Center Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 11: 165-8 (2001) BindingDB Entry DOI: 10.7270/Q2Z03BB2
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474770 (CHEMBL353965) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C19H16F3NO4S/c1-18(2)17(24)15(12-4-3-5-13(10-12)19(20,21)22)16(27-18)11-6-8-14(9-7-11)28(23,25)26/h3-10H,1-2H3,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26.7	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222643 (CHEMBL157688) Show SMILES CC(C)N(CCCc1ccc(O)cc1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2OS/c1-17(2)23(16-6-9-19-10-12-20(24)13-11-19)21(25)22-15-14-18-7-4-3-5-8-18/h3-5,7-8,10-13,17,24H,6,9,14-16H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222634 (CHEMBL157473) Show SMILES CCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2O2S/c1-3-23(21(26)22-14-13-17-8-5-4-6-9-17)15-7-10-18-11-12-19(24)20(16-18)25-2/h4-6,8-9,11-12,16,24H,3,7,10,13-15H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222692 (CHEMBL348634) Show SMILES CCCCCCCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C27H40N2O2S/c1-3-4-5-6-7-11-20-29(27(32)28-19-18-23-13-9-8-10-14-23)21-12-15-24-16-17-25(30)26(22-24)31-2/h8-10,13-14,16-17,22,30H,3-7,11-12,15,18-21H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474765 (CHEMBL353959) Show SMILES CC(=O)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(N)(=O)=O |t:10| Show InChI InChI=1S/C20H19NO5S/c1-12(22)13-4-6-14(7-5-13)17-18(26-20(2,3)19(17)23)15-8-10-16(11-9-15)27(21,24)25/h4-11H,1-3H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33.7	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474746 (CHEMBL423083) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H16ClNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37.1	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474771 (CHEMBL352602) Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(c(F)c1)S(N)(=O)=O |c:4| Show InChI InChI=1S/C18H14F3NO4S/c1-18(2)17(23)15(10-5-11(19)8-12(20)6-10)16(26-18)9-3-4-14(13(21)7-9)27(22,24)25/h3-8H,1-2H3,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50.3	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474766 (CHEMBL166720) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1F)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H16ClFO4S/c1-19(2)18(22)16(11-5-4-6-12(20)9-11)17(25-19)14-8-7-13(10-15(14)21)26(3,23)24/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50.7	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218974 (CHEMBL296206) Show SMILES CCCc1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O |t:10| Show InChI InChI=1S/C22H24O4S/c1-5-6-15-7-9-16(10-8-15)19-20(26-22(2,3)21(19)23)17-11-13-18(14-12-17)27(4,24)25/h7-14H,5-6H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Pacific Corporation R&D Center Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 11: 165-8 (2001) BindingDB Entry DOI: 10.7270/Q2Z03BB2
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	52.4	n/a	n/a	n/a	n/a	n/a	n/a
Pacific Corporation R&D Center Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 11: 165-8 (2001) BindingDB Entry DOI: 10.7270/Q2Z03BB2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	52.4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218964 (CHEMBL44223) Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52.9	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages				Bioorg Med Chem Lett 14: 1757-60 (2004) BindingDB Entry DOI: 10.7270/Q2ZK5JVW
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218973 (CHEMBL44001) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17FO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55.5	n/a	n/a	n/a	n/a	n/a	n/a
Pacific Corporation R&D Center Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 11: 165-8 (2001) BindingDB Entry DOI: 10.7270/Q2Z03BB2
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218973 (CHEMBL44001) Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17FO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55.5	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474741 (CHEMBL355729) Show SMILES CCC1(CC)OC(=C(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O |c:6| Show InChI InChI=1S/C22H21F3O4S/c1-4-21(5-2)20(26)18(14-6-10-16(11-7-14)22(23,24)25)19(29-21)15-8-12-17(13-9-15)30(3,27)28/h6-13H,4-5H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68.4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474762 (CHEMBL166378) Show SMILES CCC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:5| Show InChI InChI=1S/C20H18Cl2O4S/c1-4-20(2)19(23)17(13-9-14(21)11-15(22)10-13)18(26-20)12-5-7-16(8-6-12)27(3,24)25/h5-11H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70.5	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50474774 (CHEMBL352430) Show SMILES CC1(C)OC(=C(C1=O)c1ccc(Br)cc1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17BrO4S/c1-19(2)18(21)16(12-4-8-14(20)9-5-12)17(24-19)13-6-10-15(11-7-13)25(3,22)23/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71.2	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474774 (CHEMBL352430) Show SMILES CC1(C)OC(=C(C1=O)c1ccc(Br)cc1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H17BrO4S/c1-19(2)18(21)16(12-4-8-14(20)9-5-12)17(24-19)13-6-10-15(11-7-13)25(3,22)23/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71.2	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218970 (CHEMBL43893) Show SMILES CC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H16Cl2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	72.9	n/a	n/a	n/a	n/a	n/a	n/a
Pacific Corporation R&D Center Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages				Bioorg Med Chem Lett 11: 165-8 (2001) BindingDB Entry DOI: 10.7270/Q2Z03BB2
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50218970 (CHEMBL43893) Show SMILES CC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H16Cl2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	72.9	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50474752 (CHEMBL352329) Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1F)S(C)(=O)=O |c:4| Show InChI InChI=1S/C19H15F3O4S/c1-19(2)18(23)16(10-6-11(20)8-12(21)7-10)17(26-19)14-5-4-13(9-15(14)22)27(3,24)25/h4-9H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	75.7	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
					More data for this Ligand-Target Pair

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