Compile Data Set for Download or QSAR

Found 221 hits with Last Name = 'lin' and Initial = 'sj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Homo sapiens (Human))	BDBM50548088 (CHEMBL3040038) Show SMILES CCc1nc(N)nc(N)c1OCCCOc1ccccc1CCC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DHFR				Citation and Details Article DOI: 10.1039/d0md00303d BindingDB Entry DOI: 10.7270/Q26H4N1G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563825 (CHEMBL4794859) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(C)(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50110355 (CHEMBL3605457) Show SMILES CCS(=O)(=O)N1CCC(CC1)[C@@H](C)n1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563820 (CHEMBL4779123) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C(=O)OC(C)C)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563825 (CHEMBL4794859) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(C)(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563818 (CHEMBL4781657) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(C)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563823 (CHEMBL4799137) Show SMILES CCOC(=O)CN1CCC(CC1)[C@@H](C)n1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563822 (CHEMBL4779426) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C2COC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519290 (CHEMBL4525926) Show SMILES COc1ccc(cc1OC)N(Cc1ccc(F)cc1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C23H27FN4O2S/c1-17-14-25-16-27(17)12-4-11-26-23(31)28(15-18-5-7-19(24)8-6-18)20-9-10-21(29-2)22(13-20)30-3/h5-10,13-14,16H,4,11-12,15H2,1-3H3,(H,26,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563826 (CHEMBL4782143) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)(F)C(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519285 (CHEMBL4445407) Show SMILES COc1ccc(cc1OC)N(CCCCc1ccnc(NCCN)c1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C27H39N7O3/c1-21-19-29-20-33(21)15-6-12-32-27(35)34(23-8-9-24(36-2)25(18-23)37-3)16-5-4-7-22-10-13-30-26(17-22)31-14-11-28/h8-10,13,17-20H,4-7,11-12,14-16,28H2,1-3H3,(H,30,31)(H,32,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563822 (CHEMBL4779426) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C2COC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563818 (CHEMBL4781657) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(C)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563827 (CHEMBL4797333) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563817 (CHEMBL4787149) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCNCC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50541920 (Cpi-1205 | Lirametostat) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)(F)F)CC2)c2ccccc12 Show InChI InChI=1S/C27H33F3N4O3/c1-16-13-23(37-4)21(25(35)32-16)14-31-26(36)24-18(3)34(22-8-6-5-7-20(22)24)17(2)19-9-11-33(12-10-19)15-27(28,29)30/h5-8,13,17,19H,9-12,14-15H2,1-4H3,(H,31,36)(H,32,35)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563824 (CHEMBL4777385) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CCC(F)(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563823 (CHEMBL4799137) Show SMILES CCOC(=O)CN1CCC(CC1)[C@@H](C)n1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563819 (CHEMBL4800227) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C(=O)C(C)C)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50110355 (CHEMBL3605457) Show SMILES CCS(=O)(=O)N1CCC(CC1)[C@@H](C)n1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519280 (CHEMBL4464130) Show SMILES COc1ccc(cc1OC)N(C(C)C)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C19H28N4O2S/c1-14(2)23(16-7-8-17(24-4)18(11-16)25-5)19(26)21-9-6-10-22-13-20-12-15(22)3/h7-8,11-14H,6,9-10H2,1-5H3,(H,21,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50541920 (Cpi-1205 | Lirametostat) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)(F)F)CC2)c2ccccc12 Show InChI InChI=1S/C27H33F3N4O3/c1-16-13-23(37-4)21(25(35)32-16)14-31-26(36)24-18(3)34(22-8-6-5-7-20(22)24)17(2)19-9-11-33(12-10-19)15-27(28,29)30/h5-8,13,17,19H,9-12,14-15H2,1-4H3,(H,31,36)(H,32,35)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563821 (CHEMBL4780697) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C(=O)N(C)C)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type EZH2 in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins follow...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563826 (CHEMBL4782143) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)(F)C(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519269 (CHEMBL4539841) Show SMILES COc1ccc(cc1OC)N(Cc1cccc(F)c1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C23H27FN4O2S/c1-17-14-25-16-27(17)11-5-10-26-23(31)28(15-18-6-4-7-19(24)12-18)20-8-9-21(29-2)22(13-20)30-3/h4,6-9,12-14,16H,5,10-11,15H2,1-3H3,(H,26,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519268 (CHEMBL4586501) Show SMILES COc1ccc(cc1OC)N(Cc1cccc(Cl)c1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C23H27ClN4O2S/c1-17-14-25-16-27(17)11-5-10-26-23(31)28(15-18-6-4-7-19(24)12-18)20-8-9-21(29-2)22(13-20)30-3/h4,6-9,12-14,16H,5,10-11,15H2,1-3H3,(H,26,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519240 (CHEMBL4547037) Show SMILES COc1ccc(cc1OC)N(CCCCc1ccnc(N)c1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C25H34N6O3/c1-19-17-27-18-30(19)13-6-11-29-25(32)31(21-8-9-22(33-2)23(16-21)34-3)14-5-4-7-20-10-12-28-24(26)15-20/h8-10,12,15-18H,4-7,11,13-14H2,1-3H3,(H2,26,28)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563827 (CHEMBL4797333) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563817 (CHEMBL4787149) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCNCC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519259 (CHEMBL4448303) Show SMILES COc1ccc(cc1OC)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C23H27FN4O3/c1-17-14-25-16-27(17)12-4-11-26-23(29)28(15-18-5-7-19(24)8-6-18)20-9-10-21(30-2)22(13-20)31-3/h5-10,13-14,16H,4,11-12,15H2,1-3H3,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Institute of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of ovine COX1				Bioorg Med Chem Lett 16: 4440-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.036 BindingDB Entry DOI: 10.7270/Q2ZS2W33
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519272 (CHEMBL4445143) Show SMILES COc1ccc(cc1OC)N(CC1CCCC1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C22H32N4O2S/c1-17-14-23-16-25(17)12-6-11-24-22(29)26(15-18-7-4-5-8-18)19-9-10-20(27-2)21(13-19)28-3/h9-10,13-14,16,18H,4-8,11-12,15H2,1-3H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563820 (CHEMBL4779123) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC2)C(=O)OC(C)C)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50237457 (CHEMBL4097599) Show SMILES COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 Show InChI InChI=1S/C24H32N6O2S/c1-18-16-26-17-30(18)12-5-10-28-24(33)29-20-7-8-21(22(15-20)31-2)32-13-4-3-6-19-9-11-27-23(25)14-19/h7-9,11,14-17H,3-6,10,12-13H2,1-2H3,(H2,25,27)(H2,28,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519261 (CHEMBL4549443) Show SMILES COc1ccc(cc1OC)N(C1CCCCC1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C22H32N4O3/c1-17-15-23-16-25(17)13-7-12-24-22(27)26(18-8-5-4-6-9-18)19-10-11-20(28-2)21(14-19)29-3/h10-11,14-16,18H,4-9,12-13H2,1-3H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519298 (CHEMBL4459792) Show SMILES COc1ccc(cc1OC)N(Cc1ccccc1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C23H28N4O2S/c1-18-15-24-17-26(18)13-7-12-25-23(30)27(16-19-8-5-4-6-9-19)20-10-11-21(28-2)22(14-20)29-3/h4-6,8-11,14-15,17H,7,12-13,16H2,1-3H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519274 (CHEMBL4462968) Show SMILES COc1ccc(cc1OC)N(C1CCCCC1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C22H32N4O2S/c1-17-15-23-16-25(17)13-7-12-24-22(29)26(18-8-5-4-6-9-18)19-10-11-20(27-2)21(14-19)28-3/h10-11,14-16,18H,4-9,12-13H2,1-3H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50563824 (CHEMBL4777385) Show SMILES COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CCC(F)(F)F)CC2)c2ccccc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EZH2 Y641F mutant in PRC2 complex (unknown origin) using RKQLATKAARK(Me3)SAPATGGVKKP-NH2 peptide substrate preincubated for 30 mins fol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FQB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
National Research Institute of Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of COX1 assessed as TBX2 production in human whole blood				Bioorg Med Chem Lett 16: 4440-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.036 BindingDB Entry DOI: 10.7270/Q2ZS2W33
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519267 (CHEMBL4590359) Show SMILES COc1ccc(cc1OC)N(Cc1ccc(Cl)cc1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C23H27ClN4O2S/c1-17-14-25-16-27(17)12-4-11-26-23(31)28(15-18-5-7-19(24)8-6-18)20-9-10-21(29-2)22(13-20)30-3/h5-10,13-14,16H,4,11-12,15H2,1-3H3,(H,26,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519266 (CHEMBL4472311) Show SMILES COc1ccc(cc1OC)N(Cc1cccnc1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C22H27N5O2S/c1-17-13-24-16-26(17)11-5-10-25-22(30)27(15-18-6-4-9-23-14-18)19-7-8-20(28-2)21(12-19)29-3/h4,6-9,12-14,16H,5,10-11,15H2,1-3H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519265 (CHEMBL4459555) Show SMILES COc1ccc(cc1OC)N(Cc1ccncc1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C22H27N5O2S/c1-17-14-24-16-26(17)12-4-9-25-22(30)27(15-18-7-10-23-11-8-18)19-5-6-20(28-2)21(13-19)29-3/h5-8,10-11,13-14,16H,4,9,12,15H2,1-3H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519243 (CHEMBL4589039) Show SMILES COc1ccc(cc1OC)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C22H33N5O3/c1-17-15-23-16-26(17)11-5-10-24-22(28)27(18-8-12-25(2)13-9-18)19-6-7-20(29-3)21(14-19)30-4/h6-7,14-16,18H,5,8-13H2,1-4H3,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519297 (CHEMBL4446821) Show SMILES COc1ccc(cc1OC)N(CC1CCCC1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C22H32N4O3/c1-17-14-23-16-25(17)12-6-11-24-22(27)26(15-18-7-4-5-8-18)19-9-10-20(28-2)21(13-19)29-3/h9-10,13-14,16,18H,4-8,11-12,15H2,1-3H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519293 (CHEMBL4582369) Show SMILES COc1ccc(cc1OC)N(C1CCCC1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C21H30N4O2S/c1-16-14-22-15-24(16)12-6-11-23-21(28)25(17-7-4-5-8-17)18-9-10-19(26-2)20(13-18)27-3/h9-10,13-15,17H,4-8,11-12H2,1-3H3,(H,23,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519271 (CHEMBL4520303) Show SMILES COc1ccc(cc1OC)N(CC(C)C)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C20H30N4O2S/c1-15(2)13-24(17-7-8-18(25-4)19(11-17)26-5)20(27)22-9-6-10-23-14-21-12-16(23)3/h7-8,11-12,14-15H,6,9-10,13H2,1-5H3,(H,22,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519239 (CHEMBL4448862) Show SMILES COc1ccc(cc1OC)N(C1CCN(Cc2ccccc2)CC1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C28H37N5O3/c1-22-19-29-21-32(22)15-7-14-30-28(34)33(25-10-11-26(35-2)27(18-25)36-3)24-12-16-31(17-13-24)20-23-8-5-4-6-9-23/h4-6,8-11,18-19,21,24H,7,12-17,20H2,1-3H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519263 (CHEMBL4578714) Show SMILES COc1ccc(cc1OC)N(CC(C)C)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C20H30N4O3/c1-15(2)13-24(17-7-8-18(26-4)19(11-17)27-5)20(25)22-9-6-10-23-14-21-12-16(23)3/h7-8,11-12,14-15H,6,9-10,13H2,1-5H3,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519284 (CHEMBL4471709) Show SMILES COc1ccc(cc1OC)N(C1CCNCC1)C(=O)NCCCn1cncc1C Show InChI InChI=1S/C21H31N5O3/c1-16-14-23-15-25(16)12-4-9-24-21(27)26(17-7-10-22-11-8-17)18-5-6-19(28-2)20(13-18)29-3/h5-6,13-15,17,22H,4,7-12H2,1-3H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50519237 (CHEMBL4434757) Show SMILES COc1ccc(cc1OC)N(C1CCC1)C(=S)NCCCn1cncc1C Show InChI InChI=1S/C20H28N4O2S/c1-15-13-21-14-23(15)11-5-10-22-20(27)24(16-6-4-7-16)17-8-9-18(25-2)19(12-17)26-3/h8-9,12-14,16H,4-7,10-11H2,1-3H3,(H,22,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...				J Med Chem 62: 8011-8027 (2019) Article DOI: 10.1021/acs.jmedchem.9b00751 BindingDB Entry DOI: 10.7270/Q2W0999V
					More data for this Ligand-Target Pair

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