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Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'luca' and Initial = 'vc'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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B.MOAD
DrugBank
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PC sid
UniChem
Article
PubMed
760n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577932
PNG
(CHEMBL4853982)
Show SMILES Cl.CCOCCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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UniChem
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1.90E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577931
PNG
(CHEMBL4863751)
Show SMILES Cl.CCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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UniChem
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2.10E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577917
PNG
(CHEMBL4874860)
Show SMILES Cl.CC(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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2.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577920
PNG
(CHEMBL4857780)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccc1)C1CC1)C(=O)N1CCNCC1 |r|
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4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577916
PNG
(CHEMBL4851887)
Show SMILES Cl.CC(C)N(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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UniChem
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4.60E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577919
PNG
(CHEMBL4869003)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)C1CCCCC1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
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4.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577921
PNG
(CHEMBL4860362)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccsc1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
Article
PubMed
5.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577912
PNG
(CHEMBL4852661)
Show SMILES Cl.CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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UniChem
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5.80E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577927
PNG
(CHEMBL4876911)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccn[nH]1)C1CC1)C(=O)N1CCNCC1 |r|
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8.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
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PubMed
8.90E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin R1C domain (138 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-termi...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577915
PNG
(CHEMBL4852707)
Show SMILES Cl.CCN(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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UniChem
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1.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577918
PNG
(CHEMBL4869538)
Show SMILES Cl.CC(C)(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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UniChem
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1.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577911
PNG
(CHEMBL4862286)
Show SMILES Cl.CC(C)c1ccc(CN(C)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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1.40E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577929
PNG
(CHEMBL4847343)
Show SMILES CN1CCN(CC1)C(=O)C(C)(C)Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1 |r|
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UniChem
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PubMed
3.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577926
PNG
(CHEMBL4871689)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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3.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577930
PNG
(CHEMBL4855433)
Show SMILES CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCCCC1 |r|
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UniChem
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PubMed
4.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577913
PNG
(CHEMBL4873635)
Show SMILES CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r|
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UniChem
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4.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577922
PNG
(CHEMBL4869034)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccn1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
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5.40E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577923
PNG
(CHEMBL4868531)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cccnc1)C1CC1)C(=O)N1CCNCC1 |r|
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6.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577928
PNG
(CHEMBL4864467)
Show SMILES Cl.Cn1cc(cn1)-c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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6.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577924
PNG
(CHEMBL4858087)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccncc1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
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7.40E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577914
PNG
(CHEMBL4868665)
Show SMILES CC(C)c1ccc(CNC(=O)[C@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r|
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>9.00E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 870n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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UniChem
Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-interact...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577932
PNG
(CHEMBL4853982)
Show SMILES Cl.CCOCCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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n/an/a 2.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577931
PNG
(CHEMBL4863751)
Show SMILES Cl.CCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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n/an/a 2.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577917
PNG
(CHEMBL4874860)
Show SMILES Cl.CC(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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n/an/a 3.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577920
PNG
(CHEMBL4857780)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccc1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 4.50E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577916
PNG
(CHEMBL4851887)
Show SMILES Cl.CC(C)N(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577919
PNG
(CHEMBL4869003)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)C1CCCCC1)C1CC1)C(=O)N1CCNCC1 |r|
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TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577921
PNG
(CHEMBL4860362)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccsc1)C1CC1)C(=O)N1CCNCC1 |r|
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TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577912
PNG
(CHEMBL4852661)
Show SMILES Cl.CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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n/an/a 6.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577927
PNG
(CHEMBL4876911)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccn[nH]1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 8.90E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 9.80E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin R1C domain (138 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-termi...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
Catenin beta-1


(Homo sapiens (Human))
BDBM50577925
PNG
(CHEMBL4846565)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 1.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of beta-catenin (unknown origin) transfected in HEK293 cells cotransfected with pCMV-RL assessed as reduction in luciferase activity measu...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577915
PNG
(CHEMBL4852707)
Show SMILES Cl.CCN(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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n/an/a 1.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577918
PNG
(CHEMBL4869538)
Show SMILES Cl.CC(C)(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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n/an/a 1.40E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577911
PNG
(CHEMBL4862286)
Show SMILES Cl.CC(C)c1ccc(CN(C)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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n/an/a 1.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
Catenin beta-1


(Homo sapiens (Human))
BDBM50577931
PNG
(CHEMBL4863751)
Show SMILES Cl.CCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r|
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n/an/a 1.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of beta-catenin (unknown origin) transfected in HEK293 cells cotransfected with pCMV-RL assessed as reduction in luciferase activity measu...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577926
PNG
(CHEMBL4871689)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 3.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577929
PNG
(CHEMBL4847343)
Show SMILES CN1CCN(CC1)C(=O)C(C)(C)Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1 |r|
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n/an/a 3.90E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577913
PNG
(CHEMBL4873635)
Show SMILES CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r|
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n/an/a 5.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577930
PNG
(CHEMBL4855433)
Show SMILES CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCCCC1 |r|
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n/an/a 5.30E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577922
PNG
(CHEMBL4869034)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccn1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 5.90E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577923
PNG
(CHEMBL4868531)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cccnc1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 7.30E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577928
PNG
(CHEMBL4864467)
Show SMILES Cl.Cn1cc(cn1)-c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r|
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n/an/a 7.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577924
PNG
(CHEMBL4858087)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccncc1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a 8.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
B-cell CLL/lymphoma 9 protein


(Homo sapiens)
BDBM50577914
PNG
(CHEMBL4868665)
Show SMILES CC(C)c1ccc(CNC(=O)[C@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r|
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n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
More data for this
Ligand-Target Pair
Catenin beta-1


(Homo sapiens (Human))
BDBM50577926
PNG
(CHEMBL4871689)
Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r|
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n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of beta-catenin (unknown origin) transfected in HEK293 cells cotransfected with pCMV-RL assessed as reduction in luciferase activity measu...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00742
BindingDB Entry DOI: 10.7270/Q2SN0DSK
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Ligand-Target Pair
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