Compile Data Set for Download or QSAR

Found 1864 hits with Last Name = 'mönning' and Initial = 'u'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555116 (3-[(3,5-difluorophenyl)amino]-2-[3-(2-methoxy-2-me...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cc(F)cc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555115 (3-[(3,5-difluorophenyl)amino]-2-[3-(2-methoxyethox...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cc(F)cc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555112 (3-[(3-fluorophenyl)amino]-2-[3-(2-methoxy-2-methyl...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555110 (3-[(3-fluorophenyl)amino]-2-[3-(2-hydroxy-2-methyl...) Show SMILES CC(C)(O)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555118 (3-[(2-bromo-3-fluorophenyl)amino]-2-[3-(2-methoxye...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0860	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555136 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cc(F)cc(F)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0970	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555137 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) Show SMILES COc1c(F)cc(F)cc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0990	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555123 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COc1c(F)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.113	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555124 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555110 (3-[(3-fluorophenyl)amino]-2-[3-(2-hydroxy-2-methyl...) Show SMILES CC(C)(O)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.131	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555122 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.138	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555127 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.138	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555126 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.149	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555125 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.155	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555137 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) Show SMILES COc1c(F)cc(F)cc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.161	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555128 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1CC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.176	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555123 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COc1c(F)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.177	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555136 (3-[(3,5-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cc(F)cc(F)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.209	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555112 (3-[(3-fluorophenyl)amino]-2-[3-(2-methoxy-2-methyl...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.212	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555122 (3-[(3-fluoro-2-methoxyphenyl)amino]-2-[3-(2-methox...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.212	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555127 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.213	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555118 (3-[(2-bromo-3-fluorophenyl)amino]-2-[3-(2-methoxye...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.218	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555117 (3-{[2-(difluoromethoxy)phenyl]amino}-2-[3-(2-metho...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1ccccc1OC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555125 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.239	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555135 (3-[(3,4-difluoro-2-methoxyphenyl)amino]-2-[3-(2-me...) Show SMILES COc1c(F)c(F)ccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.246	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555129 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1CC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.259	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571467 ((+)-4-chloro-15-(2-hydroxyethyl)-2,3-dimethyl-7-{3...) Show SMILES Cc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555132 (3-[(2-ethoxy-3-fluorophenyl)amino]-2-[3-(2-methoxy...) Show SMILES CCOc1c(F)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCC(C)(C)OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.268	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555103 (2-[3-(benzyloxy)pyridin-4-yl]-3-[(3-fluorophenyl)a...) Show SMILES Fc1cccc(Nc2c([nH]c3CCNC(=O)c23)-c2ccncc2OCc2ccccc2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555124 (3-{[2-(difluoromethoxy)-3-fluorophenyl]amino}-2-[3...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1OC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555128 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1CC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.309	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555114 (3-[(3-fluorophenyl)amino]-2-(3-{[(2S)-1-methylpyrr...) Show SMILES CN1CCC[C@H]1COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] (Homo sapiens (Human))	BDBM562371 ((rac)-2,3,14-trimethyl-15-[2-(rac)-(morpholin-4-yl...) Show SMILES CN1C(CCN2CCOCC2)c2nn(C)c(C)c2-c2cccc3c(CCCOc4cccc5ccccc45)c(C(O)=O)n(CCCS1(=O)=O)c23 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930XCJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555126 (3-[(3-fluoro-2-methylphenyl)amino]-2-[3-(2-methoxy...) Show SMILES COCCOc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.322	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571478 ((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...) Show SMILES CCc1c-2c(nn1C)C(CCOC)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] (Homo sapiens (Human))	BDBM562369 ((−)-4-chloro-14-cyclopropyl-7-{3-[(6-fluoro-...) Show SMILES Cc1c-2c(CN(C3CC3)S(=O)(=O)CCCn3c(C(O)=O)c(CCCOc4cccc5cc(F)ccc45)c4ccc(Cl)c-2c34)nn1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930XCJ
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] (Homo sapiens (Human))	BDBM562401 (4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-yl)ox...) Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)N(C)S(=O)CCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930XCJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [669-770,'SVD',771-1210] (Homo sapiens (Human))	BDBM555129 (3-{[2-(2,2-difluoroethyl)-3-fluorophenyl]amino}-2-...) Show SMILES COC(C)(C)COc1cnccc1-c1[nH]c2CCNC(=O)c2c1Nc1cccc(F)c1CC(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.342	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H70K0Q
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571511 ((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...) Show SMILES CCc1c-2c(nn1C)C(CCC(C)(C)O)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571483 ((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...) Show SMILES CCc1c-2c(nn1C)[C@@H](CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571480 ((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...) Show SMILES CCc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] (Homo sapiens (Human))	BDBM562377 ((rac)-4-chloro-7-{3-[(6-fluoro-1-naphthyl)oxy]prop...) Show SMILES CN1C(CCN2CCOCC2)c2nn(C)c(C)c2-c2c(Cl)ccc3c(CCCOc4cccc5cc(F)ccc45)c(C(O)=O)n(CCCS1(=O)=O)c23 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930XCJ
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571489 ((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...) Show SMILES CCc1c-2c(nn1C)C(CC(C)(C)O)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571514 ((+)-4-chloro-15-[2-(3,3-difluoroazetidin-1-yl)ethy...) Show SMILES CCc1c-2c(nn1C)C(CCN1CC(F)(F)C1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM544485 ((rac)-12-ethyl-13-fluoro-1-(3-((6-fluoronaphthalen...) Show SMILES CCc1c-2c(COCCCCn3c(C(O)=O)c(CCCOc4cccc5cc(F)ccc45)c4ccc(F)c-2c34)nn1C Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1 Assay: In the assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1....				Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MWD
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571525 ((+)-4-chloro-3-ethyl-12,12-difluoro-7-{3-[(6-fluor...) Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCC(F)(F)CCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571497 (4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-yl)ox...) Show SMILES CCc1c-2c(nn1C)C(CCC1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571473 ((rac)-4-chloro-(15-rac)-(2-methoxyethyl)-2,3-dimet...) Show SMILES COCCC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-321]/Noxa BH3 Peptide (Homo sapiens (Human))	BDBM571486 ((+)-3-ethyl-4-fluoro-7-{3-[(6-fluoronaphthalen-1-y...) Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(F)c-2c13 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The dose-dependent inhibition by the compounds described in this invention of the interaction between MCL-1 and the BH3 domain of Noxa (both human) w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J38WT5
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43] (Homo sapiens (Human))	BDBM562386 ((+)-4-chloro-3,14-diethyl-7-{3-[(6-fluoronaphthale...) Show SMILES CCN1Cc2nn(C)c(CC)c2-c2c(Cl)ccc3c(CCCOc4cccc5cc(F)ccc45)c(C(O)=O)n(CCCS1(=O)=O)c23 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2930XCJ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1864 total )  |  Next  |  Last  >>

Jump to: