Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat)) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level incubated... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat)) | BDBM50285610 (CBV | CHEMBL4170268) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level incubated... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Displacement of 3H-CP-55940 from recombinant full length human CB2 receptor expressed in HEK293 cell membranes after 90 mins by topcount scintillatio... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50285610 (CBV | CHEMBL4170268) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus) | BDBM50285610 (CBV | CHEMBL4170268) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Displacement of 3H-CP-55940 from recombinant full length human CB1 receptor expressed in HEK293 cell membranes after 90 mins by topcount scintillatio... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50285610 (CBV | CHEMBL4170268) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.78E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Displacement of 3H-CP-55940 from recombinant full length human CB2 receptor expressed in HEK293 cell membranes after 90 mins by topcount scintillatio... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50285610 (CBV | CHEMBL4170268) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus) | BDBM50285610 (CBV | CHEMBL4170268) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluorescence as... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel, subfamily V, member 3 (Rattus norvegicus) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50285610 (CBV | CHEMBL4170268) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluorescence as... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus) | BDBM50061117 (6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Agonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50285610 (CBV | CHEMBL4170268) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 565 | n/a | n/a | n/a | n/a |
University of Eastern Piedmont Curated by ChEMBL | Assay Description Displacement of 3H-CP-55940 from recombinant full length human CB1 receptor expressed in HEK293 cell membranes after 90 mins by topcount scintillatio... | J Nat Prod 81: 630-633 (2018) Article DOI: 10.1021/acs.jnatprod.7b00946 BindingDB Entry DOI: 10.7270/Q26D5WJF | |||||||||||
More data for this Ligand-Target Pair |