Found 141 hits with Last Name = 'mayfield' and Initial = 'ca' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM16312
((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)Show InChI InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
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| PDB PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description The compound was tested for the inhibition of Aldose reductase in rat lens assay. |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM16312
((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)Show InChI InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
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| PDB PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM) |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016618
(CHEMBL8370 | [(3-Nitro-benzoyl)-(4-nitro-phenyl)-a...)Show SMILES OC(=O)CN(C(=O)c1cccc(c1)[N+]([O-])=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O7/c19-14(20)9-16(11-4-6-12(7-5-11)17(22)23)15(21)10-2-1-3-13(8-10)18(24)25/h1-8H,9H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.02 -0.64 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM16312
((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)Show InChI InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
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| PDB PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM16312
((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)Show InChI InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
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| PDB PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM16312
((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)Show InChI InChI=1S/C11H9FN2O3/c12-6-1-2-8-7(5-6)11(3-4-17-8)9(15)13-10(16)14-11/h1-2,5H,3-4H2,(H2,13,14,15,16)/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PDB PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.07 - 1.2 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50010002
(CHEMBL302057 | [(4-Benzoylamino-benzoyl)-phenyl-am...)Show SMILES OC(=O)CN(C(=O)c1ccc(NC(=O)c2ccccc2)cc1)c1ccccc1 Show InChI InChI=1S/C22H18N2O4/c25-20(26)15-24(19-9-5-2-6-10-19)22(28)17-11-13-18(14-12-17)23-21(27)16-7-3-1-4-8-16/h1-14H,15H2,(H,23,27)(H,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016553
(CHEMBL36108 | [(4-Benzoylamino-benzenesulfonyl)-ph...)Show SMILES OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C21H18N2O5S/c24-20(25)15-23(18-9-5-2-6-10-18)29(27,28)19-13-11-17(12-14-19)22-21(26)16-7-3-1-4-8-16/h1-14H,15H2,(H,22,26)(H,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016557
((Naphthalene-2-sulfonylamino)-acetic acid | CHEMBL...)Show InChI InChI=1S/C12H11NO4S/c14-12(15)8-13-18(16,17)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,13H,8H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016550
((4-Benzoylamino-benzenesulfonylamino)-acetic acid ...)Show InChI InChI=1S/C15H14N2O5S/c18-14(19)10-16-23(21,22)13-8-6-12(7-9-13)17-15(20)11-4-2-1-3-5-11/h1-9,16H,10H2,(H,17,20)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
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| PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009985
(CHEMBL69716 | [(4-Nitro-benzoyl)-phenyl-amino]-ace...)Show SMILES OC(=O)CN(C(=O)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C15H12N2O5/c18-14(19)10-16(12-4-2-1-3-5-12)15(20)11-6-8-13(9-7-11)17(21)22/h1-9H,10H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016609
((2-Oxo-2H-benzo[cd]indol-1-yl)-acetic acid | CHEMB...)Show InChI InChI=1S/C13H9NO3/c15-11(16)7-14-10-6-2-4-8-3-1-5-9(12(8)10)13(14)17/h1-6H,7H2,(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.15 - 3.3 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022333
(CHEMBL41232 | [4-(3-Phenyl-acryloylamino)-benzenes...)Show SMILES OC(=O)CNS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O5S/c20-16(11-6-13-4-2-1-3-5-13)19-14-7-9-15(10-8-14)25(23,24)18-12-17(21)22/h1-11,18H,12H2,(H,19,20)(H,21,22)/b11-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016598
(CHEMBL8786 | [Benzoyl-(3-nitro-phenyl)-amino]-acet...)Show SMILES OC(=O)CN(C(=O)c1ccccc1)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C15H12N2O5/c18-14(19)10-16(15(20)11-5-2-1-3-6-11)12-7-4-8-13(9-12)17(21)22/h1-9H,10H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.3 - 2.3 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016550
((4-Benzoylamino-benzenesulfonylamino)-acetic acid ...)Show InChI InChI=1S/C15H14N2O5S/c18-14(19)10-16-23(21,22)13-8-6-12(7-9-13)17-15(20)11-4-2-1-3-5-11/h1-9,16H,10H2,(H,17,20)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016604
(CHEMBL267531 | [Benzoyl-(4-methoxy-phenyl)-amino]-...)Show InChI InChI=1S/C16H15NO4/c1-21-14-9-7-13(8-10-14)17(11-15(18)19)16(20)12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.1 - 7 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016572
(CHEMBL286389 | [(3-Nitro-benzenesulfonyl)-phenyl-a...)Show SMILES OC(=O)CN(c1ccccc1)S(=O)(=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C14H12N2O6S/c17-14(18)10-15(11-5-2-1-3-6-11)23(21,22)13-8-4-7-12(9-13)16(19)20/h1-9H,10H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016549
(CHEMBL37072 | [(4-Methoxy-benzenesulfonyl)-phenyl-...)Show InChI InChI=1S/C15H15NO5S/c1-21-13-7-9-14(10-8-13)22(19,20)16(11-15(17)18)12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022337
((4-Phenylacetylamino-benzenesulfonylamino)-acetic ...)Show InChI InChI=1S/C16H16N2O5S/c19-15(10-12-4-2-1-3-5-12)18-13-6-8-14(9-7-13)24(22,23)17-11-16(20)21/h1-9,17H,10-11H2,(H,18,19)(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50367835
(CHEMBL1907953)Show SMILES OC(=O)[C@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1 |r| Show InChI InChI=1S/C18H15NO4S/c20-18(21)17(14-7-2-1-3-8-14)19-24(22,23)16-11-10-13-6-4-5-9-15(13)12-16/h1-12,17,19H,(H,20,21)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022338
(CHEMBL417523 | [4-(2-Phenoxy-acetylamino)-benzenes...)Show SMILES OC(=O)CNS(=O)(=O)c1ccc(NC(=O)COc2ccccc2)cc1 Show InChI InChI=1S/C16H16N2O6S/c19-15(11-24-13-4-2-1-3-5-13)18-12-6-8-14(9-7-12)25(22,23)17-10-16(20)21/h1-9,17H,10-11H2,(H,18,19)(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022334
(CHEMBL40666 | [4-(3-Phenyl-ureido)-benzenesulfonyl...)Show InChI InChI=1S/C15H15N3O5S/c19-14(20)10-16-24(22,23)13-8-6-12(7-9-13)18-15(21)17-11-4-2-1-3-5-11/h1-9,16H,10H2,(H,19,20)(H2,17,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009990
(CHEMBL305251 | [(4-Benzoylamino-benzoyl)-methyl-am...)Show InChI InChI=1S/C17H16N2O4/c1-19(11-15(20)21)17(23)13-7-9-14(10-8-13)18-16(22)12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H,18,22)(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016596
((Benzoyl-p-tolyl-amino)-acetic acid | CHEMBL275007)Show InChI InChI=1S/C16H15NO3/c1-12-7-9-14(10-8-12)17(11-15(18)19)16(20)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.5 - 16 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009983
(CHEMBL308898 | [(4-Methoxy-benzoyl)-phenyl-amino]-...)Show InChI InChI=1S/C16H15NO4/c1-21-14-9-7-12(8-10-14)16(20)17(11-15(18)19)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022342
(CHEMBL40681 | [4-(2-Benzyloxy-acetylamino)-benzene...)Show SMILES OC(=O)CNS(=O)(=O)c1ccc(NC(=O)COCc2ccccc2)cc1 Show InChI InChI=1S/C17H18N2O6S/c20-16(12-25-11-13-4-2-1-3-5-13)19-14-6-8-15(9-7-14)26(23,24)18-10-17(21)22/h1-9,18H,10-12H2,(H,19,20)(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016591
(CHEMBL34976 | [(2-Nitro-benzenesulfonyl)-phenyl-am...)Show SMILES OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C14H12N2O6S/c17-14(18)10-15(11-6-2-1-3-7-11)23(21,22)13-9-5-4-8-12(13)16(19)20/h1-9H,10H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009992
(CHEMBL69549 | [(4-Methyl-benzoyl)-phenyl-amino]-ac...)Show InChI InChI=1S/C16H15NO3/c1-12-7-9-13(10-8-12)16(20)17(11-15(18)19)14-5-3-2-4-6-14/h2-10H,11H2,1H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022345
((4-Acetylamino-benzenesulfonylamino)-acetic acid |...)Show InChI InChI=1S/C10H12N2O5S/c1-7(13)12-8-2-4-9(5-3-8)18(16,17)11-6-10(14)15/h2-5,11H,6H2,1H3,(H,12,13)(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016551
(CHEMBL37003 | [(4-Nitro-benzenesulfonyl)-phenyl-am...)Show SMILES OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H12N2O6S/c17-14(18)10-15(11-4-2-1-3-5-11)23(21,22)13-8-6-12(7-9-13)16(19)20/h1-9H,10H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016576
(CHEMBL35870 | [(Naphthalene-2-sulfonyl)-phenyl-ami...)Show InChI InChI=1S/C18H15NO4S/c20-18(21)13-19(16-8-2-1-3-9-16)24(22,23)17-11-10-14-6-4-5-7-15(14)12-17/h1-12H,13H2,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016600
(CHEMBL274433 | [Benzoyl-(4-chloro-phenyl)-amino]-a...)Show InChI InChI=1S/C15H12ClNO3/c16-12-6-8-13(9-7-12)17(10-14(18)19)15(20)11-4-2-1-3-5-11/h1-9H,10H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 1.5 - 16 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016582
(2-(Naphthalene-2-sulfonylamino)-benzoic acid | CHE...)Show InChI InChI=1S/C17H13NO4S/c19-17(20)15-7-3-4-8-16(15)18-23(21,22)14-10-9-12-5-1-2-6-13(12)11-14/h1-11,18H,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016594
(CHEMBL8607 | [Acetyl-(4-nitro-phenyl)-amino]-aceti...)Show InChI InChI=1S/C10H10N2O5/c1-7(13)11(6-10(14)15)8-2-4-9(5-3-8)12(16)17/h2-5H,6H2,1H3,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 0.6 - 47 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009980
(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(15-9-2-1-3-10-15)19(23)17-12-6-8-14-7-4-5-11-16(14)17/h1-12H,13H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibition of aldose reductase from rat lens. Value ranges from 1.0 - 34 |
J Med Chem 32: 1033-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CV4GQC |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022336
((4-Benzyloxycarbonylamino-benzenesulfonylamino)-ac...)Show SMILES OC(=O)CNS(=O)(=O)c1ccc(NOC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C16H16N2O6S/c19-15(20)11-17-25(22,23)14-8-6-13(7-9-14)18-24-16(21)10-12-4-2-1-3-5-12/h1-9,17-18H,10-11H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 6.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009997
((Benzoyl-phenyl-amino)-acetic acid | CHEMBL273228)Show InChI InChI=1S/C15H13NO3/c17-14(18)11-16(13-9-5-2-6-10-13)15(19)12-7-3-1-4-8-12/h1-10H,11H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009978
(CHEMBL66711 | [(4-Methoxy-benzoyl)-methyl-amino]-a...)Show InChI InChI=1S/C11H13NO4/c1-12(7-10(13)14)11(15)8-3-5-9(16-2)6-4-8/h3-6H,7H2,1-2H3,(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022339
((4-Benzylamino-benzenesulfonylamino)-acetic acid |...)Show InChI InChI=1S/C15H16N2O4S/c18-15(19)11-17-22(20,21)14-8-6-13(7-9-14)16-10-12-4-2-1-3-5-12/h1-9,16-17H,10-11H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50367829
(CHEMBL1907951)Show SMILES OC(=O)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C14H12ClNO4S/c15-11-6-8-12(9-7-11)21(19,20)16-13(14(17)18)10-4-2-1-3-5-10/h1-9,13,16H,(H,17,18)/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022343
((3-Benzoylamino-benzenesulfonylamino)-acetic acid ...)Show InChI InChI=1S/C15H14N2O5S/c18-14(19)10-16-23(21,22)13-8-4-7-12(9-13)17-15(20)11-5-2-1-3-6-11/h1-9,16H,10H2,(H,17,20)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 7.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016593
(CHEMBL37193 | [Benzenesulfonyl-(2-chloro-phenyl)-a...)Show InChI InChI=1S/C14H12ClNO4S/c15-12-8-4-5-9-13(12)16(10-14(17)18)21(19,20)11-6-2-1-3-7-11/h1-9H,10H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016585
(2-(4-Amino-benzenesulfonylamino)-benzoic acid | CH...)Show InChI InChI=1S/C13H12N2O4S/c14-9-5-7-10(8-6-9)20(18,19)15-12-4-2-1-3-11(12)13(16)17/h1-8,15H,14H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009984
(CHEMBL66216 | [(4-Fluoro-benzoyl)-phenyl-amino]-ac...)Show InChI InChI=1S/C15H12FNO3/c16-12-8-6-11(7-9-12)15(20)17(10-14(18)19)13-4-2-1-3-5-13/h1-9H,10H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016571
(2-(Naphthalene-1-sulfonylamino)-benzoic acid | CHE...)Show InChI InChI=1S/C17H13NO4S/c19-17(20)14-9-3-4-10-15(14)18-23(21,22)16-11-5-7-12-6-1-2-8-13(12)16/h1-11,18H,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50022340
(CHEMBL39090 | [4-(3-Phenyl-thioureido)-benzenesulf...)Show InChI InChI=1S/C15H15N3O4S2/c19-14(20)10-16-24(21,22)13-8-6-12(7-9-13)18-15(23)17-11-4-2-1-3-5-11/h1-9,16H,10H2,(H,19,20)(H2,17,18,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat aldose reductase enzyme. |
J Med Chem 30: 1595-8 (1987)
BindingDB Entry DOI: 10.7270/Q2G15ZTJ |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009980
(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)Show InChI InChI=1S/C19H15NO3/c21-18(22)13-20(15-9-2-1-3-10-15)19(23)17-12-6-8-14-7-4-5-11-16(14)17/h1-12H,13H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50367837
(CHEMBL1907773)Show SMILES OC(=O)[C@@H](NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |r| Show InChI InChI=1S/C14H12N2O6S/c17-14(18)13(10-4-2-1-3-5-10)15-23(21,22)12-8-6-11(7-9-12)16(19)20/h1-9,13,15H,(H,17,18)/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50016556
(CHEMBL284603 | [Benzenesulfonyl-(3-nitro-phenyl)-a...)Show SMILES OC(=O)CN(c1cccc(c1)[N+]([O-])=O)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H12N2O6S/c17-14(18)10-15(11-5-4-6-12(9-11)16(19)20)23(21,22)13-7-2-1-3-8-13/h1-9H,10H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory concentration against aldose reductase obtained from rat lens |
J Med Chem 32: 145-51 (1989)
BindingDB Entry DOI: 10.7270/Q2GM87WR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member B1
(Rattus norvegicus) | BDBM50009988
(CHEMBL308007 | [(4-Fluoro-benzoyl)-methyl-amino]-a...)Show InChI InChI=1S/C10H10FNO3/c1-12(6-9(13)14)10(15)7-2-4-8(11)5-3-7/h2-5H,6H2,1H3,(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PubMed
| n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Auburn University
Curated by ChEMBL
| Assay Description Inhibitory activity against aldose reductase in rat lens |
J Med Chem 34: 2120-6 (1991)
BindingDB Entry DOI: 10.7270/Q2N29VX2 |
More data for this Ligand-Target Pair | |