| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 |
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| Ligand | BDBM50022334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_31932 |
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| IC50 | 2750±n/a nM |
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| Citation |  Mayfield, CA; DeRuiter, J Novel inhibitors of rat lens aldose reductase: N-[[(substituted amino)phenyl]sulfonyl]glycines. J Med Chem30:1595-8 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Aldo-keto reductase family 1 member B1 |
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| Name: | Aldo-keto reductase family 1 member B1 |
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| Synonyms: | ALDR_RAT | Akr1b1 | Akr1b4 | Aldose reductase | Aldr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35797.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1512484 |
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| Residue: | 316 |
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| Sequence: | MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ
EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP
DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP
AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK
YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV
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| BDBM50022334 |
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| n/a |
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| Name | BDBM50022334 |
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| Synonyms: | CHEMBL40666 | [4-(3-Phenyl-ureido)-benzenesulfonylamino]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15N3O5S |
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| Mol. Mass. | 349.362 |
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| SMILES | OC(=O)CNS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 |
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| Structure | 
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