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Compile Data Set for Download or QSAR

Found 680 hits with Last Name = 'moreno' and Initial = 'j'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104394
PNG
((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Show SMILES CC1NC[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3?,4-,5?,6+/m1/s1
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 5n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104394
PNG
((4S,5R)-2-Methyl-piperidine-3,4,5-triol | CHEMBL87...)
Show SMILES CC1NC[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3?,4-,5?,6+/m1/s1
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 6n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104387
PNG
((4R,5R)-6-Hydroxymethyl-2-methyl-2,3,4,5-tetrahydr...)
Show SMILES CC1NC(CO)C(=O)[C@H](O)C1O
Show InChI InChI=1S/C7H13NO4/c1-3-5(10)7(12)6(11)4(2-9)8-3/h3-5,7-10,12H,2H2,1H3/t3?,4?,5?,7-/m1/s1
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 7n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104405
PNG
(3,4-Dihydroxy-5-methyl-pyrrolidine-2-sulfonic acid...)
Show SMILES CC1NC(C(O)C1O)S(O)(=O)=O
Show InChI InChI=1S/C5H11NO5S/c1-2-3(7)4(8)5(6-2)12(9,10)11/h2-8H,1H3,(H,9,10,11)
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 10n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104403
PNG
((2R,3S)-2-Amino-5-methyl-piperidine-3,4-diol | CHE...)
Show SMILES CC1CN[C@@H](N)[C@H](O)C1O
Show InChI InChI=1S/C6H14N2O2/c1-3-2-8-6(7)5(10)4(3)9/h3-6,8-10H,2,7H2,1H3/t3?,4?,5-,6-/m1/s1
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 16n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104402
PNG
(2-Methyl-3,4-dihydro-2H-pyrrole-3,4-diol | CHEMBL8...)
Show SMILES CC1NCC(O)C1=O
Show InChI InChI=1S/C5H9NO2/c1-3-5(8)4(7)2-6-3/h3-4,6-7H,2H2,1H3
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 160n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Alpha-galactosidase A


(Homo sapiens (Human))		BDBM50564233
PNG
(CHEMBL4792854)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 200n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104390
PNG
((R)-2-((R)-2-Allyloxy-4,5-dihydroxy-6-hydroxymethy...)
Show SMILES CC1SC(O[C@H]2C(OCC=C)OC(CO)C(O)C2O)C(O)[C@H](O)C1O
Show InChI InChI=1S/C15H26O9S/c1-3-4-22-14-13(11(20)9(18)7(5-16)23-14)24-15-12(21)10(19)8(17)6(2)25-15/h3,6-21H,1,4-5H2,2H3/t6?,7?,8?,9?,10-,11?,12?,13-,14?,15?/m1/s1
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 210n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-fucosidase of bacillus species (K40T) expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104410
PNG
((2R,3R)-4-Amino-6-methyl-cyclohexane-1,2,3-triol |...)
Show SMILES CC1CC(N)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3?,4?,5?,6-,7-/m1/s1
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 230n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104399
PNG
((R)-4-Benzylamino-5-methyl-cyclopentane-1,2,3-trio...)
Show SMILES CC1C(O)[C@@H](O)C(O)C1NCc1ccccc1
Show InChI InChI=1S/C13H19NO3/c1-8-10(12(16)13(17)11(8)15)14-7-9-5-3-2-4-6-9/h2-6,8,10-17H,7H2,1H3/t8?,10?,11?,12?,13-/m1/s1
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 680n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564233
PNG
(CHEMBL4792854)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 770n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104395
PNG
((4R,5R)-6-Hydrazino-2-methyl-2,3,4,5-tetrahydro-py...)
Show SMILES CC1N=C(NN)[C@@H](O)[C@H](O)C1O |t:2|
Show InChI InChI=1S/C6H13N3O3/c1-2-3(10)4(11)5(12)6(8-2)9-7/h2-5,10-12H,7H2,1H3,(H,8,9)/t2?,3?,4-,5+/m1/s1
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 820n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)		BDBM50321922
PNG
((3S,4S,5R,6S)-3-(p-Phenylbenzoylaminomethyl)-6-met...)
Show SMILES C[C@@H]1NN[C@@H](CNC(=O)c2ccc(cc2)-c2ccccc2)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C19H23N3O3/c1-12-17(23)18(24)16(22-21-12)11-20-19(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10,12,16-18,21-24H,11H2,1H3,(H,20,25)/t12-,16-,17+,18-/m0/s1
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 1.00E+3n/an/an/an/an/an/an/an/a



University of Seville

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha L-fucosidase

Bioorg Med Chem 18: 4648-60 (2011)


Article DOI: 10.1016/j.bmc.2010.05.026
BindingDB Entry DOI: 10.7270/Q2G161TR
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564234
PNG
(CHEMBL4783905)
Show SMILES O[C@@H]1CN[C@@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 1.10E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564237
PNG
(CHEMBL4793095)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)CCCCC(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 1.20E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50403111
PNG
(CHEMBL1289015)
Show SMILES C[C@@H]1N[C@@H](CO)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(2-8)7-3/h3-10H,2H2,1H3/t3-,4-,5+,6-/m0/s1
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 1.40E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Alpha-galactosidase A


(Homo sapiens (Human))		BDBM50564237
PNG
(CHEMBL4793095)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)CCCCC(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 1.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564238
PNG
(CHEMBL4791125)
Show SMILES O[C@@H]1CN[C@@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(COCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cnnn4CCOCCOc4ccc(cc4)-c4cn(C[C@@H]5NC[C@@H](O)[C@H]5O)nn4)nn3)cc2)[C@@H]1O |r|
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 1.60E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104401
PNG
(2-Methyl-pyrrolidine-3,4-diol | CHEMBL314405)
Show SMILES CC1NCC(O)C1O
Show InChI InChI=1S/C5H11NO2/c1-3-5(8)4(7)2-6-3/h3-8H,2H2,1H3
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 2.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564236
PNG
(CHEMBL4782789)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(COCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cnnn4CCOCCOc4ccc(cc4)-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)nn3)cc2)[C@@H]1O |r|
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 2.60E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564239
PNG
(CHEMBL4779198)
Show SMILES O[C@@H]1CN[C@@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)CCCCC(=O)NC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)cc2)[C@@H]1O |r|
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 2.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104392
PNG
((6S,7R)-2-Butylamino-4,7-bis-hydroxymethyl-[1,3]di...)
Show SMILES CCCCNC1N[C@H](CO)[C@H](O)C(O)[C@H](CO)N1
Show InChI InChI=1S/C11H25N3O4/c1-2-3-4-12-11-13-7(5-15)9(17)10(18)8(6-16)14-11/h7-18H,2-6H2,1H3/t7-,8+,9+,10?,11?/m1/s1
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 2.80E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104397
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CC(C)NC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C13H20N2O4/c1-6(2)15-13(18)8-4-10(19-7(8)3)11-12(17)9(16)5-14-11/h4,6,9,11-12,14,16-17H,5H2,1-3H3,(H,15,18)
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 3.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50403938
PNG
(CHEMBL2114150)
Show SMILES CC(C)NC(=O)c1cc(oc1C)[C@@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C13H20N2O4/c1-6(2)15-13(18)8-4-10(19-7(8)3)11-12(17)9(16)5-14-11/h4,6,9,11-12,14,16-17H,5H2,1-3H3,(H,15,18)/t9-,11+,12-/m1/s1
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 3.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive)of the compound against alpha-L-Fucosidase from Human placenta

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104396
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CCNC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C12H18N2O4/c1-3-13-12(17)7-4-9(18-6(7)2)10-11(16)8(15)5-14-10/h4,8,10-11,14-16H,3,5H2,1-2H3,(H,13,17)
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 3.20E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104398
PNG
((R)-2-Methyl-6-(4-nitro-phenylsulfanyl)-tetrahydro...)
Show SMILES CC1SC(Sc2ccc(cc2)[N+]([O-])=O)C(O)[C@H](O)C1O
Show InChI InChI=1S/C12H15NO5S2/c1-6-9(14)10(15)11(16)12(19-6)20-8-4-2-7(3-5-8)13(17)18/h2-6,9-12,14-16H,1H3/t6?,9?,10-,11?,12?/m1/s1
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 3.30E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Alpha-galactosidase A


(Homo sapiens (Human))		BDBM50564249
PNG
(CHEMBL4789325)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(CCCn3cc(COCC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)NC(=O)c4cc(cc(c4)C(=O)NC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)C(=O)NC(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cn(CCCc5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)nn3)nn2)[C@@H]1O |r|
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 3.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104406
PNG
(CHEMBL431802 | N-((3R,4R)-3,4,5-Trihydroxy-piperid...)
Show SMILES CC(=O)NCC1NCC(O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C8H16N2O4/c1-4(11)9-2-5-7(13)8(14)6(12)3-10-5/h5-8,10,12-14H,2-3H2,1H3,(H,9,11)/t5?,6?,7-,8-/m1/s1
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 4.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)		BDBM50321921
PNG
((3S,4S,5R,6S)-3-Hydroxymethyl-6-methylhexahydropyr...)
Show SMILES C[C@@H]1NN[C@@H](CO)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H14N2O3/c1-3-5(10)6(11)4(2-9)8-7-3/h3-11H,2H2,1H3/t3-,4-,5+,6-/m0/s1
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 4.20E+3n/an/an/an/an/an/an/an/a



University of Seville

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha L-fucosidase

Bioorg Med Chem 18: 4648-60 (2011)


Article DOI: 10.1016/j.bmc.2010.05.026
BindingDB Entry DOI: 10.7270/Q2G161TR
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104396
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CCNC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C12H18N2O4/c1-3-13-12(17)7-4-9(18-6(7)2)10-11(16)8(15)5-14-10/h4,8,10-11,14-16H,3,5H2,1-2H3,(H,13,17)
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 4.80E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-Fucosidase of human placenta expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104386
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CC(C)OC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C13H19NO5/c1-6(2)18-13(17)8-4-10(19-7(8)3)11-12(16)9(15)5-14-11/h4,6,9,11-12,14-16H,5H2,1-3H3
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 4.90E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory concentration against alpha-L-Fucosidase of human placenta

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50403938
PNG
(CHEMBL2114150)
Show SMILES CC(C)NC(=O)c1cc(oc1C)[C@@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C13H20N2O4/c1-6(2)15-13(18)8-4-10(19-7(8)3)11-12(17)9(16)5-14-11/h4,6,9,11-12,14,16-17H,5H2,1-3H3,(H,15,18)/t9-,11+,12-/m1/s1
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 5.30E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive) of the compound against alpha-l-Fucosidase from Human placenta

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104397
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CC(C)NC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C13H20N2O4/c1-6(2)15-13(18)8-4-10(19-7(8)3)11-12(17)9(16)5-14-11/h4,6,9,11-12,14,16-17H,5H2,1-3H3,(H,15,18)
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 5.30E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory concentration against alpha-L-Fucosidase of bovine epididymis

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Lysosomal acid glucosylceramidase


(Homo sapiens (Human))		BDBM50564235
PNG
(CHEMBL4793871)
Show SMILES NC(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1 |r|
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 5.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))		BDBM50468278
PNG
(CHEMBL4294263)
Show SMILES Cc1oc(cc1C(=O)NCc1cn(CCCCCCCCCCCCn2cc(CNC(=O)c3cc(oc3C)[C@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C38H56N10O8/c1-23-27(15-31(55-23)33-35(51)29(49)19-39-33)37(53)41-17-25-21-47(45-43-25)13-11-9-7-5-3-4-6-8-10-12-14-48-22-26(44-46-48)18-42-38(54)28-16-32(56-24(28)2)34-36(52)30(50)20-40-34/h15-16,21-22,29-30,33-36,39-40,49-52H,3-14,17-20H2,1-2H3,(H,41,53)(H,42,54)/t29-,30-,33-,34-,35-,36-/m1/s1
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 5.80E+3n/an/an/an/an/an/an/an/a



University of Seville

Curated by ChEMBL


Assay Description
Competitive inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycopyranoside as substrate preincubated for 5 mins followed by substr...

Eur J Med Chem 151: 765-776 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.008
BindingDB Entry DOI: 10.7270/Q24B341J
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens (Human))		BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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 6.40E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant against Beta-galactosidase from Jack beans; Mixed (Non competitive and competitive)

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104389
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES COC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C11H15NO5/c1-5-6(11(15)16-2)3-8(17-5)9-10(14)7(13)4-12-9/h3,7,9-10,12-14H,4H2,1-2H3
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 6.50E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory concentration against alpha-L-Fucosidase of bovine epididymis

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens (Human))		BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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 6.60E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitor concentration of the compound against alpha-L-Fucosidase from Bovine epididymis

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Alpha-galactosidase A


(Homo sapiens (Human))		BDBM50564236
PNG
(CHEMBL4782789)
Show SMILES O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccc(OCCOCCn3cc(COCC(COCc4cn(CCOCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)(COCc4cn(COCCOc5ccc(cc5)-c5cn(C[C@H]6NC[C@@H](O)[C@H]6O)nn5)nn4)COCc4cnnn4CCOCCOc4ccc(cc4)-c4cn(C[C@H]5NC[C@@H](O)[C@H]5O)nn4)nn3)cc2)[C@@H]1O |r|
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MMDB

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 7.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112173
BindingDB Entry DOI: 10.7270/Q2H998X6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104412
PNG
((S)-5-Methyl-piperidine-3,4-diol | CHEMBL86305)
Show SMILES CC1CNC[C@H](O)C1O
Show InChI InChI=1S/C6H13NO2/c1-4-2-7-3-5(8)6(4)9/h4-9H,2-3H2,1H3/t4?,5-,6?/m0/s1
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 8.40E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104386
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CC(C)OC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C13H19NO5/c1-6(2)18-13(17)8-4-10(19-7(8)3)11-12(16)9(15)5-14-11/h4,6,9,11-12,14-16H,5H2,1-3H3
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 8.60E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-Fucosidase of human placenta expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104388
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CCOC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3
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 9.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50403870
PNG
(CHEMBL1289017)
Show SMILES C[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(2-8)7-3/h3-10H,2H2,1H3/t3-,4-,5-,6+/m1/s1
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 9.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney.

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50220499
PNG
(CHEMBL3350284)
Show SMILES CCOC(=O)c1cc(oc1C)[C@@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10+,11-/m1/s1
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 9.00E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive) against alpha-L-Fucosidase from Bovine epididymis

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50220501
PNG
(CHEMBL3350285)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12+,13-/m1/s1
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 9.10E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant of the compound against Beta-galactosidase from Bovine liver; Mixed(Competitive and Non Competitive)

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104393
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3
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 9.10E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-L-Fucosidase of bovine epididymis expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
Beta-galactosidase


(Aspergillus niger)		BDBM50403936
PNG
(CHEMBL2114148)
Show SMILES CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C12H17NO5/c1-3-17-12(16)7-4-9(18-6(7)2)10-11(15)8(14)5-13-10/h4,8,10-11,13-15H,3,5H2,1-2H3/t8-,10-,11-/m1/s1
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 9.80E+3n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Non competitive) of compound against Beta-galactosidase from Aspergillus niger

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Beta-galactosidase


(Bos taurus (Bovine))		BDBM50403937
PNG
(CHEMBL2114149)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12-,13-/m1/s1
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 1.30E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive) against Beta-galactosidase from Bovine liver

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens (Human))		BDBM50403937
PNG
(CHEMBL2114149)
Show SMILES CCN(CC)C(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H22N2O4/c1-4-16(5-2)14(19)9-6-11(20-8(9)3)12-13(18)10(17)7-15-12/h6,10,12-13,15,17-18H,4-5,7H2,1-3H3/t10-,12-,13-/m1/s1
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 1.30E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibition constant (Competitive) of the compound against Beta-galactosidasee from Aspergillus niger was tested at a dose of 1 mM

Bioorg Med Chem Lett 12: 2335-9 (2002)


BindingDB Entry DOI: 10.7270/Q2GB23CB
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Homo sapiens (Human))		BDBM50104389
PNG
(5-(3,4-Dihydroxy-pyrrolidin-2-yl)-2-methyl-furan-3...)
Show SMILES COC(=O)c1cc(oc1C)C1NCC(O)C1O
Show InChI InChI=1S/C11H15NO5/c1-5-6(11(15)16-2)3-8(17-5)9-10(14)7(13)4-12-9/h3,7,9-10,12-14H,4H2,1-2H3
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 1.38E+4n/an/an/an/an/an/an/an/a



Universidad de Sevilla

Curated by ChEMBL


Assay Description
Inhibitory activity against Beta-D-galactosidase of Aspergillus niger expressed as Ki

Bioorg Med Chem Lett 11: 2555-9 (2001)


BindingDB Entry DOI: 10.7270/Q23X8751
More data for this
Ligand-Target Pair
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