Found 120 hits with Last Name = 'morgan' and Initial = 'tm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230790
(CHEMBL292892)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C23H23N3O6S/c1-2-3-6-21-24-13-18(10-17(23(29)30)11-19-5-4-9-33-19)25(21)14-16-8-7-15(22(27)28)12-20(16)26(31)32/h4-5,7-10,12-13H,2-3,6,11,14H2,1H3,(H,27,28)(H,29,30)/b17-10+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230779
(CHEMBL294686)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)c2nn[nH]n2)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H24N6O2S/c1-2-3-6-21-24-14-19(29(21)15-16-7-9-17(10-8-16)23(30)31)12-18(22-25-27-28-26-22)13-20-5-4-11-32-20/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,30,31)(H,25,26,27,28)/b18-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230811
(CHEMBL293091)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)-c1nn[nH]n1 Show InChI InChI=1S/C23H24N6O2S/c1-2-3-6-21-24-14-19(12-18(23(30)31)13-20-5-4-11-32-20)29(21)15-16-7-9-17(10-8-16)22-25-27-28-26-22/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,30,31)(H,25,26,27,28)/b18-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230778
(CHEMBL56211)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(N)=O Show InChI InChI=1S/C23H25N3O3S/c1-2-3-6-21-25-14-19(12-18(23(28)29)13-20-5-4-11-30-20)26(21)15-16-7-9-17(10-8-16)22(24)27/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H2,24,27)(H,28,29)/b18-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230771
(CHEMBL55510)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C23H24N2O5S/c1-2-3-6-21-24-13-17(11-16(22(27)28)12-18-5-4-9-31-18)25(21)14-15-7-8-19(23(29)30)20(26)10-15/h4-5,7-11,13,26H,2-3,6,12,14H2,1H3,(H,27,28)(H,29,30)/b16-11+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230806
(CHEMBL294415)Show SMILES CCCCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H28N2O4S/c1-2-3-4-5-8-23-26-16-21(14-20(25(30)31)15-22-7-6-13-32-22)27(23)17-18-9-11-19(12-10-18)24(28)29/h6-7,9-14,16H,2-5,8,15,17H2,1H3,(H,28,29)(H,30,31)/b20-14+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50048078
(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(C(O)=O)c(Cl)c1 Show InChI InChI=1S/C23H23ClN2O4S/c1-2-3-6-21-25-13-17(11-16(22(27)28)12-18-5-4-9-31-18)26(21)14-15-7-8-19(23(29)30)20(24)10-15/h4-5,7-11,13H,2-3,6,12,14H2,1H3,(H,27,28)(H,29,30)/b16-11+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50011975
(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1Cl)C(O)=O Show InChI InChI=1S/C23H23ClN2O4S/c1-2-3-6-21-25-13-18(10-17(23(29)30)11-19-5-4-9-31-19)26(21)14-16-8-7-15(22(27)28)12-20(16)24/h4-5,7-10,12-13H,2-3,6,11,14H2,1H3,(H,27,28)(H,29,30)/b17-10+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230787
(CHEMBL54421)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(C(O)=O)c(c1)-c1ccccc1 Show InChI InChI=1S/C29H28N2O4S/c1-2-3-11-27-30-18-23(16-22(28(32)33)17-24-10-7-14-36-24)31(27)19-20-12-13-25(29(34)35)26(15-20)21-8-5-4-6-9-21/h4-10,12-16,18H,2-3,11,17,19H2,1H3,(H,32,33)(H,34,35)/b22-16+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230799
(CHEMBL56333)Show SMILES CCCCc1ncc(\C=C(/CCc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H26N2O4S/c1-2-3-6-22-25-15-20(14-19(24(29)30)11-12-21-5-4-13-31-21)26(22)16-17-7-9-18(10-8-17)23(27)28/h4-5,7-10,13-15H,2-3,6,11-12,16H2,1H3,(H,27,28)(H,29,30)/b19-14+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230792
(CHEMBL56497)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C23H24N2O4S/c1-2-3-9-21-24-14-19(12-18(23(28)29)13-20-8-5-10-30-20)25(21)15-16-6-4-7-17(11-16)22(26)27/h4-8,10-12,14H,2-3,9,13,15H2,1H3,(H,26,27)(H,28,29)/b18-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230774
(CHEMBL291955)Show SMILES CCCCc1ncc(\C=C(/Cc2ccccc2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H26N2O4/c1-2-3-9-23-26-16-22(15-21(25(30)31)14-18-7-5-4-6-8-18)27(23)17-19-10-12-20(13-11-19)24(28)29/h4-8,10-13,15-16H,2-3,9,14,17H2,1H3,(H,28,29)(H,30,31)/b21-15+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230762
(CHEMBL56160)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C22H25N3O4S2/c1-2-3-6-21-24-14-18(12-17(22(26)27)13-19-5-4-11-30-19)25(21)15-16-7-9-20(10-8-16)31(23,28)29/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H2,23,28,29)/b17-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230810
(CHEMBL299064)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(C(O)=O)c(c1)C(O)=O Show InChI InChI=1S/C24H24N2O6S/c1-2-3-6-21-25-13-17(11-16(22(27)28)12-18-5-4-9-33-18)26(21)14-15-7-8-19(23(29)30)20(10-15)24(31)32/h4-5,7-11,13H,2-3,6,12,14H2,1H3,(H,27,28)(H,29,30)(H,31,32)/b16-11+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230764
(CHEMBL299954)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(=O)NCC(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H27N3O5S/c1-2-3-6-22-26-14-20(28(22)16-17-7-9-18(10-8-17)25(32)33)12-19(13-21-5-4-11-34-21)24(31)27-15-23(29)30/h4-5,7-12,14H,2-3,6,13,15-16H2,1H3,(H,27,31)(H,29,30)(H,32,33)/b19-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230767
(CHEMBL56522)Show SMILES CCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H22N2O4S/c1-2-4-20-23-13-18(11-17(22(27)28)12-19-5-3-10-29-19)24(20)14-15-6-8-16(9-7-15)21(25)26/h3,5-11,13H,2,4,12,14H2,1H3,(H,25,26)(H,27,28)/b17-11+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230796
(CHEMBL56690)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H28N2O4S/c1-2-3-10-27-30-18-23(16-22(28(32)33)17-24-7-6-15-36-24)31(27)19-20-11-13-21(14-12-20)25-8-4-5-9-26(25)29(34)35/h4-9,11-16,18H,2-3,10,17,19H2,1H3,(H,32,33)(H,34,35)/b22-16+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230772
(CHEMBL59043)Show SMILES CCCc1cccc(\C=C(/Cc2cccs2)C(O)=O)c1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H24O4S/c1-2-5-18-6-3-7-20(15-21(25(28)29)16-22-8-4-13-30-22)23(18)14-17-9-11-19(12-10-17)24(26)27/h3-4,6-13,15H,2,5,14,16H2,1H3,(H,26,27)(H,28,29)/b21-15+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230805
(CHEMBL54645)Show SMILES CCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C21H21N3O4S/c1-2-6-20-22-13-17(11-16(21(25)26)12-18-8-5-10-29-18)23(20)14-15-7-3-4-9-19(15)24(27)28/h3-5,7-11,13H,2,6,12,14H2,1H3,(H,25,26)/b16-11+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50011978
(3-[2-Butyl-3-(4-hydroxy-3-methyl-benzyl)-3H-imidaz...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(O)c(C)c1 Show InChI InChI=1S/C23H26N2O3S/c1-3-4-7-22-24-14-19(12-18(23(27)28)13-20-6-5-10-29-20)25(22)15-17-8-9-21(26)16(2)11-17/h5-6,8-12,14,26H,3-4,7,13,15H2,1-2H3,(H,27,28)/b18-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230785
(CHEMBL300566)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(N)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H25N3O3S/c1-2-3-6-21-25-14-19(12-18(22(24)27)13-20-5-4-11-30-20)26(21)15-16-7-9-17(10-8-16)23(28)29/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H2,24,27)(H,28,29)/b18-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230783
(CHEMBL54711)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1C#N Show InChI InChI=1S/C23H23N3O2S/c1-2-3-10-22-25-15-20(12-19(23(27)28)13-21-9-6-11-29-21)26(22)16-18-8-5-4-7-17(18)14-24/h4-9,11-12,15H,2-3,10,13,16H2,1H3,(H,27,28)/b19-12+ | PDB
UniProtKB/SwissProt
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SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230809
(CHEMBL57620)Show SMILES CCCC\C(=C/c1cnc(CCCC)n1Cc1ccc(cc1)C(O)=O)C(O)=O Show InChI InChI=1S/C22H28N2O4/c1-3-5-7-18(22(27)28)13-19-14-23-20(8-6-4-2)24(19)15-16-9-11-17(12-10-16)21(25)26/h9-14H,3-8,15H2,1-2H3,(H,25,26)(H,27,28)/b18-13+ | PDB
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230791
(CHEMBL55950)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(=O)OCC Show InChI InChI=1S/C25H28N2O4S/c1-3-5-8-23-26-16-21(14-20(24(28)29)15-22-7-6-13-32-22)27(23)17-18-9-11-19(12-10-18)25(30)31-4-2/h6-7,9-14,16H,3-5,8,15,17H2,1-2H3,(H,28,29)/b20-14+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50011974
(3-[2-Butyl-3-(2-nitro-benzyl)-3H-imidazol-4-yl]-2-...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C22H23N3O4S/c1-2-3-10-21-23-14-18(12-17(22(26)27)13-19-8-6-11-30-19)24(21)15-16-7-4-5-9-20(16)25(28)29/h4-9,11-12,14H,2-3,10,13,15H2,1H3,(H,26,27)/b17-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50011971
(3-[2-Butyl-3-(2-hydroxy-benzyl)-3H-imidazol-4-yl]-...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1O Show InChI InChI=1S/C22H24N2O3S/c1-2-3-10-21-23-14-18(24(21)15-16-7-4-5-9-20(16)25)12-17(22(26)27)13-19-8-6-11-28-19/h4-9,11-12,14,25H,2-3,10,13,15H2,1H3,(H,26,27)/b17-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230781
(CHEMBL291688)Show SMILES CCCCc1ncc(\C=C(/CC2CCCS2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H28N2O4S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27/h7-10,12,14,20H,2-6,11,13,15H2,1H3,(H,26,27)(H,28,29)/b18-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230795
(CHEMBL59580)Show SMILES CC(C)CCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H26N2O4S/c1-16(2)5-10-22-25-14-20(12-19(24(29)30)13-21-4-3-11-31-21)26(22)15-17-6-8-18(9-7-17)23(27)28/h3-4,6-9,11-12,14,16H,5,10,13,15H2,1-2H3,(H,27,28)(H,29,30)/b19-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50048076
(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cc(Cl)c(cc1Cl)C(O)=O Show InChI InChI=1S/C23H22Cl2N2O4S/c1-2-3-6-21-26-12-16(8-14(22(28)29)9-17-5-4-7-32-17)27(21)13-15-10-20(25)18(23(30)31)11-19(15)24/h4-5,7-8,10-12H,2-3,6,9,13H2,1H3,(H,28,29)(H,30,31)/b14-8+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230804
(CHEMBL293706)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(=O)OC Show InChI InChI=1S/C24H26N2O4S/c1-3-4-7-22-25-15-20(13-19(23(27)28)14-21-6-5-12-31-21)26(22)16-17-8-10-18(11-9-17)24(29)30-2/h5-6,8-13,15H,3-4,7,14,16H2,1-2H3,(H,27,28)/b19-13+ | PDB
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| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230770
(CHEMBL55216)Show SMILES CCCCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C24H27N3O4S/c1-2-3-4-5-12-23-25-16-20(14-19(24(28)29)15-21-10-8-13-32-21)26(23)17-18-9-6-7-11-22(18)27(30)31/h6-11,13-14,16H,2-5,12,15,17H2,1H3,(H,28,29)/b19-14+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230768
(CHEMBL417752)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cccc(Cl)c1Cl Show InChI InChI=1S/C22H22Cl2N2O2S/c1-2-3-9-20-25-13-17(11-16(22(27)28)12-18-7-5-10-29-18)26(20)14-15-6-4-8-19(23)21(15)24/h4-8,10-11,13H,2-3,9,12,14H2,1H3,(H,27,28)/b16-11+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230801
(CHEMBL301632)Show SMILES CCCCc1ncc(CC(Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H26N2O4S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27/h4-5,7-11,14,18H,2-3,6,12-13,15H2,1H3,(H,26,27)(H,28,29) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230088
(CHEMBL125786)Show SMILES CCCCc1ncc(\C=C(/Cc2ccc(O)c(O)c2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C24H25ClN2O4/c1-2-3-8-23-26-14-19(27(23)15-17-6-4-5-7-20(17)25)13-18(24(30)31)11-16-9-10-21(28)22(29)12-16/h4-7,9-10,12-14,28-29H,2-3,8,11,15H2,1H3,(H,30,31)/b18-13+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase II |
J Med Chem 35: 3858-72 (1992)
BindingDB Entry DOI: 10.7270/Q23T9G4T |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230769
(CHEMBL56085)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C24H26N2O4S/c1-2-3-6-22-25-15-20(13-19(24(29)30)14-21-5-4-11-31-21)26(22)16-18-9-7-17(8-10-18)12-23(27)28/h4-5,7-11,13,15H,2-3,6,12,14,16H2,1H3,(H,27,28)(H,29,30)/b19-13+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230773
(CHEMBL55357)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H26N2O4S/c1-2-3-6-22-25-16-20(14-19(24(29)30)15-21-5-4-13-31-21)26(22)12-11-17-7-9-18(10-8-17)23(27)28/h4-5,7-10,13-14,16H,2-3,6,11-12,15H2,1H3,(H,27,28)(H,29,30)/b19-14+ | PDB
UniProtKB/SwissProt
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UniChem
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| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230776
(CHEMBL54982)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(OC)c(C)c1 Show InChI InChI=1S/C24H28N2O3S/c1-4-5-8-23-25-15-20(13-19(24(27)28)14-21-7-6-11-30-21)26(23)16-18-9-10-22(29-3)17(2)12-18/h6-7,9-13,15H,4-5,8,14,16H2,1-3H3,(H,27,28)/b19-13+ | PDB
UniProtKB/SwissProt
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UniChem
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| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor B
(RAT) | BDBM50003292
(3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2...)Show SMILES CCCCc1ncc(\C=C(/Cc2ccc(OC)s2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C23H25ClN2O3S/c1-3-4-9-21-25-14-18(26(21)15-16-7-5-6-8-20(16)24)12-17(23(27)28)13-19-10-11-22(29-2)30-19/h5-8,10-12,14H,3-4,9,13,15H2,1-2H3,(H,27,28)/b17-12+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]-Angiotensin II receptor specific binding to rat mesenteric arteries |
J Med Chem 35: 3858-72 (1992)
BindingDB Entry DOI: 10.7270/Q23T9G4T |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230777
(CHEMBL54446)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(N)=O)n1Cc1ccc(cc1)C(N)=O Show InChI InChI=1S/C23H26N4O2S/c1-2-3-6-21-26-14-19(12-18(23(25)29)13-20-5-4-11-30-20)27(21)15-16-7-9-17(10-8-16)22(24)28/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H2,24,28)(H2,25,29)/b18-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230808
(CHEMBL54576)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C#N Show InChI InChI=1S/C23H23N3O2S/c1-2-3-6-22-25-15-20(12-19(23(27)28)13-21-5-4-11-29-21)26(22)16-18-9-7-17(14-24)8-10-18/h4-5,7-12,15H,2-3,6,13,16H2,1H3,(H,27,28)/b19-12+ | PDB
UniProtKB/SwissProt
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| CHEMBL
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UniChem
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| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230079
(CHEMBL126594)Show SMILES CCCCc1ncc(\C=C(/Cc2ccc(O)cc2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C24H25ClN2O3/c1-2-3-8-23-26-15-20(27(23)16-18-6-4-5-7-22(18)25)14-19(24(29)30)13-17-9-11-21(28)12-10-17/h4-7,9-12,14-15,28H,2-3,8,13,16H2,1H3,(H,29,30)/b19-14+ | PDB
UniProtKB/SwissProt
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| CHEMBL
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UniChem
| PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]angiotensin II specific binding to rat mesenteric arteries |
J Med Chem 35: 3858-72 (1992)
BindingDB Entry DOI: 10.7270/Q23T9G4T |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230803
(CHEMBL54459)Show SMILES CCCCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C24H27ClN2O2S/c1-2-3-4-5-12-23-26-16-20(27(23)17-18-9-6-7-11-22(18)25)14-19(24(28)29)15-21-10-8-13-30-21/h6-11,13-14,16H,2-5,12,15,17H2,1H3,(H,28,29)/b19-14+ | PDB
UniProtKB/SwissProt
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| CHEMBL
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UniChem
| PubMed
| n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230775
(CHEMBL57677)Show SMILES CCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O2S/c1-2-6-20-23-13-17(24(20)14-15-7-3-4-9-19(15)22)11-16(21(25)26)12-18-8-5-10-27-18/h3-5,7-11,13H,2,6,12,14H2,1H3,(H,25,26)/b16-11+ | PDB
UniProtKB/SwissProt
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| CHEMBL
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| n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230794
(CHEMBL59157)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cccc(OC)c1[N+]([O-])=O Show InChI InChI=1S/C23H25N3O5S/c1-3-4-10-21-24-14-18(12-17(23(27)28)13-19-8-6-11-32-19)25(21)15-16-7-5-9-20(31-2)22(16)26(29)30/h5-9,11-12,14H,3-4,10,13,15H2,1-2H3,(H,27,28)/b17-12+ | PDB
UniProtKB/SwissProt
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UniChem
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| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230114
(CHEMBL339961)Show SMILES CCCCc1ncc(\C=C(/Cc2ccncc2)C(O)=O)n1Cc1ccccc1Cl Show InChI InChI=1S/C23H24ClN3O2/c1-2-3-8-22-26-15-20(27(22)16-18-6-4-5-7-21(18)24)14-19(23(28)29)13-17-9-11-25-12-10-17/h4-7,9-12,14-15H,2-3,8,13,16H2,1H3,(H,28,29)/b19-14+ | PDB
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| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase II |
J Med Chem 35: 3858-72 (1992)
BindingDB Entry DOI: 10.7270/Q23T9G4T |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230759
(CHEMBL291329)Show SMILES CC(C)Cc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H24N2O4S/c1-15(2)10-21-24-13-19(11-18(23(28)29)12-20-4-3-9-30-20)25(21)14-16-5-7-17(8-6-16)22(26)27/h3-9,11,13,15H,10,12,14H2,1-2H3,(H,26,27)(H,28,29)/b18-11+ | PDB
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| n/a | n/a | 163 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230807
(CHEMBL292165)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cccc(OC)c1 Show InChI InChI=1S/C23H26N2O3S/c1-3-4-10-22-24-15-19(13-18(23(26)27)14-21-9-6-11-29-21)25(22)16-17-7-5-8-20(12-17)28-2/h5-9,11-13,15H,3-4,10,14,16H2,1-2H3,(H,26,27)/b18-13+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230786
(CHEMBL58981)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C22H23N3O4S/c1-2-3-9-21-23-14-19(12-17(22(26)27)13-20-8-5-10-30-20)24(21)15-16-6-4-7-18(11-16)25(28)29/h4-8,10-12,14H,2-3,9,13,15H2,1H3,(H,26,27)/b17-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230798
(CHEMBL54696)Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)c2nn[nH]n2)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C22H23N7O2S/c1-2-3-10-21-23-14-18(28(21)15-16-7-4-5-9-20(16)29(30)31)12-17(22-24-26-27-25-22)13-19-8-6-11-32-19/h4-9,11-12,14H,2-3,10,13,15H2,1H3,(H,24,25,26,27)/b17-12+ | PDB
UniProtKB/SwissProt
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| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor
(RAT) | BDBM50230765
(CHEMBL59094)Show SMILES CCCCc1cnc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H24N2O4S/c1-2-3-5-19-14-24-21(13-18(23(28)29)12-20-6-4-11-30-20)25(19)15-16-7-9-17(10-8-16)22(26)27/h4,6-11,13-14H,2-3,5,12,15H2,1H3,(H,26,27)(H,28,29)/b18-13+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
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PC cid
PC sid
UniChem
Similars
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| n/a | n/a | 248 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries |
J Med Chem 36: 1880-92 (1993)
BindingDB Entry DOI: 10.7270/Q2PK0JC7 |
More data for this
Ligand-Target Pair | |
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